FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6315, 259 aa 1>>>pF1KB6315 259 - 259 aa - 259 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3634+/-0.000901; mu= 14.5071+/- 0.054 mean_var=66.9145+/-13.156, 0's: 0 Z-trim(105.0): 19 B-trim: 51 in 1/50 Lambda= 0.156789 statistics sampled from 8176 (8191) to 8176 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.252), width: 16 Scan time: 2.190 The best scores are: opt bits E(32554) CCDS3240.1 DCUN1D1 gene_id:54165|Hs108|chr3 ( 259) 1753 405.4 2.1e-113 CCDS77862.1 DCUN1D1 gene_id:54165|Hs108|chr3 ( 244) 1658 383.9 5.8e-107 CCDS32013.1 DCUN1D2 gene_id:55208|Hs108|chr13 ( 259) 1459 338.9 2.2e-93 CCDS10592.1 DCUN1D3 gene_id:123879|Hs108|chr16 ( 304) 564 136.4 2.2e-32 CCDS8325.1 DCUN1D5 gene_id:84259|Hs108|chr11 ( 237) 484 118.3 4.9e-27 CCDS33982.1 DCUN1D4 gene_id:23142|Hs108|chr4 ( 292) 466 114.3 9.8e-26 CCDS75123.1 DCUN1D4 gene_id:23142|Hs108|chr4 ( 336) 466 114.3 1.1e-25 CCDS3487.2 DCUN1D4 gene_id:23142|Hs108|chr4 ( 257) 260 67.6 9.4e-12 >>CCDS3240.1 DCUN1D1 gene_id:54165|Hs108|chr3 (259 aa) initn: 1753 init1: 1753 opt: 1753 Z-score: 2149.6 bits: 405.4 E(32554): 2.1e-113 Smith-Waterman score: 1753; 100.0% identity (100.0% similar) in 259 aa overlap (1-259:1-259) 10 20 30 40 50 60 pF1KB6 MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 EFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 YWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLI 190 200 210 220 230 240 250 pF1KB6 DDFVEFARPQIAGTKSTTV ::::::::::::::::::: CCDS32 DDFVEFARPQIAGTKSTTV 250 >>CCDS77862.1 DCUN1D1 gene_id:54165|Hs108|chr3 (244 aa) initn: 1658 init1: 1658 opt: 1658 Z-score: 2033.8 bits: 383.9 E(32554): 5.8e-107 Smith-Waterman score: 1658; 100.0% identity (100.0% similar) in 244 aa overlap (16-259:1-244) 10 20 30 40 50 60 pF1KB6 MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSL ::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSL 10 20 30 40 70 80 90 100 110 120 pF1KB6 DRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQ 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 EFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 EFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIA 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 YWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 YWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLI 170 180 190 200 210 220 250 pF1KB6 DDFVEFARPQIAGTKSTTV ::::::::::::::::::: CCDS77 DDFVEFARPQIAGTKSTTV 230 240 >>CCDS32013.1 DCUN1D2 gene_id:55208|Hs108|chr13 (259 aa) initn: 1496 init1: 1451 opt: 1459 Z-score: 1790.2 bits: 338.9 E(32554): 2.2e-93 Smith-Waterman score: 1459; 78.2% identity (94.9% similar) in 257 aa overlap (1-257:1-257) 10 20 30 40 50 60 pF1KB6 MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSL :.:::::::::::::: ::..:.::. ::.::.:.:: :::.:::::. :::..... CCDS32 MHKLKSSQKDKVRQFMACTQAGERTAIYCLTQNEWRLDEATDSFFQNPDSLHRESMRNAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQ :.::::.::.::::::::::::.::::::::::.:::::::::.::::::::::::::.. CCDS32 DKKKLERLYGRYKDPQDENKIGVDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIA ::.::::::::::.::::: .:..:::::. ..:::::::::.:::::::::::::::.: CCDS32 EFLDGMTELGCDSMEKLKALLPRLEQELKDTAKFKDFYQFTFTFAKNPGQKGLDLEMAVA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLI ::.:::.:::::::::: ::.::::::::.:::::::::..::::::::::::::::::: CCDS32 YWKLVLSGRFKFLDLWNTFLMEHHKRSIPRDTWNLLLDFGNMIADDMSNYDEEGAWPVLI 190 200 210 220 230 240 250 pF1KB6 DDFVEFARPQIAGTKSTTV :::::.::: ..: : . CCDS32 DDFVEYARPVVTGGKRSLF 250 >>CCDS10592.1 DCUN1D3 gene_id:123879|Hs108|chr16 (304 aa) initn: 556 init1: 295 opt: 564 Z-score: 695.0 bits: 136.4 E(32554): 2.2e-32 Smith-Waterman score: 564; 43.9% identity (77.2% similar) in 189 aa overlap (63-246:89-276) 40 50 60 70 80 90 pF1KB6 NDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDD ..::.:. :::: . :. : .:...::.: CCDS10 AEAATEACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDER-EDAILEEGMERFCND 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 LALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPG : .::. . ::..::::.:::.:.:...::.:: .. :::. . :..:.. : :. CCDS10 LCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQED 120 130 140 150 160 170 160 170 180 190 200 pF1KB6 RFKDFYQFTFNFA--KNPGQKGLDLEMAIAYWNLVLN-GRFKFLDLWNKFLLEHHK--RS .:::.:.:::.:. .. ::..: :.::: :.::.. . :: : .:: :. . .. CCDS10 KFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKG 180 190 200 210 220 230 210 220 230 240 250 pF1KB6 IPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV : .::::..:.:. .:. :.:::.:. ::: :.: :::. CCDS10 ISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREGEGRGALSSGPEG 240 250 260 270 280 290 CCDS10 LCPEEQT 300 >>CCDS8325.1 DCUN1D5 gene_id:84259|Hs108|chr11 (237 aa) initn: 481 init1: 450 opt: 484 Z-score: 598.9 bits: 118.3 E(32554): 4.9e-27 Smith-Waterman score: 484; 36.0% identity (73.7% similar) in 186 aa overlap (63-248:49-232) 40 50 60 70 80 90 pF1KB6 NDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDD :: . .: : :: .: .:...::.: CCDS83 DGGLKKCKISSYCRSQPPARLISGEEHFSSKKCLAWFYEYAGP-DEV-VGPEGMEKFCED 20 30 40 50 60 70 100 110 120 130 140 150 pF1KB6 LALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPG ....: .: .:..:::..: .. :.:.:.. ::: : :: :::. .. ....:.. . CCDS83 IGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQNKFDFLRSQLNDIS 80 90 100 110 120 130 160 170 180 190 200 210 pF1KB6 RFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDT ::..:...:.::.. :..::.. : .. :.:. . ..... ..: . . : . :: CCDS83 SFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLLGRTWPLFSVFYQYLEQSKYRVMNKDQ 140 150 160 170 180 190 220 230 240 250 pF1KB6 WNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV : .:.:: . :.:::::.::::::.:.:::. . CCDS83 WYNVLEFSRTVHADLSNYDEDGAWPVLLDEFVEWQKVRQTS 200 210 220 230 >>CCDS33982.1 DCUN1D4 gene_id:23142|Hs108|chr4 (292 aa) initn: 462 init1: 435 opt: 466 Z-score: 575.5 bits: 114.3 E(32554): 9.8e-26 Smith-Waterman score: 466; 35.4% identity (71.4% similar) in 189 aa overlap (62-250:104-289) 40 50 60 70 80 90 pF1KB6 QNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCD .. :: .:. : .: .: .:...::. CCDS33 DLSAKKSRHDSMYRKYDSTRIKTEEEAFSSKRCLEWFYE-YAGTDDV--VGPEGMEKFCE 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 DLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEP :....: .. .:..:::. : .. :. ::.. ::: : ::. :::. . ... :.. CCDS33 DIGVEPENVVMLVLAWKLDAQNMGYFTLQEWLKGMTSLQCDTTEKLRNTLDYLRSFLNDS 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB6 GRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKD :: .:...:.::.. :..::.. : . .:.:. . .. ....:: . . . : :: CCDS33 TNFKLIYRYAFDFAREKDQRSLDINTAKCMLGLLLGKIWPLFPVFHQFLEQSKYKVINKD 200 210 220 230 240 250 220 230 240 250 pF1KB6 TWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV : .:.:: : :.:::::.::::::.:.:::. . . CCDS33 QWCNVLEFSRTINLDLSNYDEDGAWPVLLDEFVEWYKDKQMS 260 270 280 290 >>CCDS75123.1 DCUN1D4 gene_id:23142|Hs108|chr4 (336 aa) initn: 462 init1: 435 opt: 466 Z-score: 574.6 bits: 114.3 E(32554): 1.1e-25 Smith-Waterman score: 466; 35.4% identity (71.4% similar) in 189 aa overlap (62-250:148-333) 40 50 60 70 80 90 pF1KB6 QNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCD .. :: .:. : .: .: .:...::. CCDS75 DLSAKKSRHDSMYRKYDSTRIKTEEEAFSSKRCLEWFYE-YAGTDDV--VGPEGMEKFCE 120 130 140 150 160 170 100 110 120 130 140 150 pF1KB6 DLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEP :....: .. .:..:::. : .. :. ::.. ::: : ::. :::. . ... :.. CCDS75 DIGVEPENVVMLVLAWKLDAQNMGYFTLQEWLKGMTSLQCDTTEKLRNTLDYLRSFLNDS 180 190 200 210 220 230 160 170 180 190 200 210 pF1KB6 GRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKD :: .:...:.::.. :..::.. : . .:.:. . .. ....:: . . . : :: CCDS75 TNFKLIYRYAFDFAREKDQRSLDINTAKCMLGLLLGKIWPLFPVFHQFLEQSKYKVINKD 240 250 260 270 280 290 220 230 240 250 pF1KB6 TWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV : .:.:: : :.:::::.::::::.:.:::. . . CCDS75 QWCNVLEFSRTINLDLSNYDEDGAWPVLLDEFVEWYKDKQMS 300 310 320 330 >>CCDS3487.2 DCUN1D4 gene_id:23142|Hs108|chr4 (257 aa) initn: 405 init1: 222 opt: 260 Z-score: 324.5 bits: 67.6 E(32554): 9.4e-12 Smith-Waterman score: 347; 32.3% identity (59.3% similar) in 189 aa overlap (62-250:104-254) 40 50 60 70 80 90 pF1KB6 QNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCD .. :: .:. : .: .: .:...::. CCDS34 DLSAKKSRHDSMYRKYDSTRIKTEEEAFSSKRCLEWFYE-YAGTDDV--VGPEGMEKFCE 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 DLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEP :....: .. .:..:::. : .. :. ::.. ::: : ::. :::. . ... :.. CCDS34 DIGVEPENVVMLVLAWKLDAQNMGYFTLQEWLKGMTSLQCDTTEKLRNTLDYLRSFLNDS 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB6 GRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKD :: .:...:.::.. : :.: :: CCDS34 TNFKLIYRYAFDFARQSKYK-------------VIN----------------------KD 200 210 220 230 240 250 pF1KB6 TWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV : .:.:: : :.:::::.::::::.:.:::. . . CCDS34 QWCNVLEFSRTINLDLSNYDEDGAWPVLLDEFVEWYKDKQMS 220 230 240 250 259 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:36:52 2016 done: Sat Nov 5 16:36:52 2016 Total Scan time: 2.190 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]