FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6319, 260 aa 1>>>pF1KB6319 260 - 260 aa - 260 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4133+/-0.000344; mu= 14.5921+/- 0.022 mean_var=68.3058+/-13.427, 0's: 0 Z-trim(114.9): 16 B-trim: 63 in 3/55 Lambda= 0.155183 statistics sampled from 24935 (24945) to 24935 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.292), width: 16 Scan time: 6.470 The best scores are: opt bits E(85289) NP_001010844 (OMIM: 615375) interleukin-1 receptor ( 260) 1675 383.6 1.9e-106 XP_011533749 (OMIM: 615375) PREDICTED: interleukin ( 257) 1604 367.7 1.1e-101 XP_006715399 (OMIM: 615375) PREDICTED: interleukin ( 279) 1604 367.8 1.2e-101 XP_016865753 (OMIM: 615375) PREDICTED: interleukin ( 156) 824 193.0 2.7e-49 XP_016865754 (OMIM: 615375) PREDICTED: interleukin ( 150) 805 188.7 5.1e-48 XP_011533750 (OMIM: 615375) PREDICTED: interleukin ( 157) 804 188.5 6.1e-48 >>NP_001010844 (OMIM: 615375) interleukin-1 receptor-ass (260 aa) initn: 1675 init1: 1675 opt: 1675 Z-score: 2032.2 bits: 383.6 E(85289): 1.9e-106 Smith-Waterman score: 1675; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260) 10 20 30 40 50 60 pF1KB6 MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 AYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEGQIDDHQSSRLSSSLTVQQKIKSATIHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEGQIDDHQSSRLSSSLTVQQKIKSATIHA 190 200 210 220 230 240 250 260 pF1KB6 ASKVFITFEVKGKEKRKKHL :::::::::::::::::::: NP_001 ASKVFITFEVKGKEKRKKHL 250 260 >>XP_011533749 (OMIM: 615375) PREDICTED: interleukin-1 r (257 aa) initn: 1604 init1: 1604 opt: 1604 Z-score: 1946.4 bits: 367.7 E(85289): 1.1e-101 Smith-Waterman score: 1604; 100.0% identity (100.0% similar) in 249 aa overlap (1-249:1-249) 10 20 30 40 50 60 pF1KB6 MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 AYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEGQIDDHQSSRLSSSLTVQQKIKSATIHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEGQIDDHQSSRLSSSLTVQQKIKSATIHA 190 200 210 220 230 240 250 260 pF1KB6 ASKVFITFEVKGKEKRKKHL ::::::::: XP_011 ASKVFITFEKLLRRGGV 250 >>XP_006715399 (OMIM: 615375) PREDICTED: interleukin-1 r (279 aa) initn: 1604 init1: 1604 opt: 1604 Z-score: 1945.8 bits: 367.8 E(85289): 1.2e-101 Smith-Waterman score: 1604; 100.0% identity (100.0% similar) in 249 aa overlap (1-249:1-249) 10 20 30 40 50 60 pF1KB6 MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 AYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEGQIDDHQSSRLSSSLTVQQKIKSATIHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEGQIDDHQSSRLSSSLTVQQKIKSATIHA 190 200 210 220 230 240 250 260 pF1KB6 ASKVFITFEVKGKEKRKKHL ::::::::: XP_006 ASKVFITFEQLLESFFNIPTNNYSQIAMSPVNYHESHIK 250 260 270 >>XP_016865753 (OMIM: 615375) PREDICTED: interleukin-1 r (156 aa) initn: 824 init1: 824 opt: 824 Z-score: 1005.9 bits: 193.0 E(85289): 2.7e-49 Smith-Waterman score: 824; 100.0% identity (100.0% similar) in 126 aa overlap (124-249:1-126) 100 110 120 130 140 150 pF1KB6 YITQSLQQQGVQAENITVTKDFRRVENAYHMEAEVCITFTEFGKMQNICNFLVEKLDSSV :::::::::::::::::::::::::::::: XP_016 MEAEVCITFTEFGKMQNICNFLVEKLDSSV 10 20 30 160 170 180 190 200 210 pF1KB6 VISPPQFYHTPGSVENLRRQACLVAVENAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VISPPQFYHTPGSVENLRRQACLVAVENAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEG 40 50 60 70 80 90 220 230 240 250 260 pF1KB6 QIDDHQSSRLSSSLTVQQKIKSATIHAASKVFITFEVKGKEKRKKHL :::::::::::::::::::::::::::::::::::: XP_016 QIDDHQSSRLSSSLTVQQKIKSATIHAASKVFITFEQLLESFFNIPTNNYSQIAMSPVNY 100 110 120 130 140 150 XP_016 HESHIK >>XP_016865754 (OMIM: 615375) PREDICTED: interleukin-1 r (150 aa) initn: 804 init1: 804 opt: 805 Z-score: 983.1 bits: 188.7 E(85289): 5.1e-48 Smith-Waterman score: 805; 92.2% identity (95.0% similar) in 141 aa overlap (1-141:1-140) 10 20 30 40 50 60 pF1KB6 MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 AYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVE ::::::: : .. ::.. XP_016 AYHMEAEKLHIFEKIF-MQSVPLKCISYESI 130 140 150 >>XP_011533750 (OMIM: 615375) PREDICTED: interleukin-1 r (157 aa) initn: 804 init1: 804 opt: 804 Z-score: 981.6 bits: 188.5 E(85289): 6.1e-48 Smith-Waterman score: 804; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KB6 MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 AYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVE ::::::: XP_011 AYHMEAEQLLESFFNIPTNNYSQIAMSPVNYHESHIK 130 140 150 260 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:41:29 2016 done: Fri Nov 4 22:41:30 2016 Total Scan time: 6.470 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]