FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6320, 282 aa 1>>>pF1KB6320 282 - 282 aa - 282 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.7692+/-0.000457; mu= -10.7773+/- 0.029 mean_var=502.2075+/-104.271, 0's: 0 Z-trim(123.6): 3 B-trim: 813 in 1/56 Lambda= 0.057231 statistics sampled from 43654 (43667) to 43654 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.512), width: 16 Scan time: 7.150 The best scores are: opt bits E(85289) NP_004587 (OMIM: 182285) U1 small nuclear ribonucl ( 282) 1917 171.8 1.3e-42 NP_003083 (OMIM: 603520) U2 small nuclear ribonucl ( 225) 614 64.1 2.8e-10 NP_937863 (OMIM: 603520) U2 small nuclear ribonucl ( 225) 614 64.1 2.8e-10 >>NP_004587 (OMIM: 182285) U1 small nuclear ribonucleopr (282 aa) initn: 1917 init1: 1917 opt: 1917 Z-score: 885.8 bits: 171.8 E(85289): 1.3e-42 Smith-Waterman score: 1917; 100.0% identity (100.0% similar) in 282 aa overlap (1-282:1-282) 10 20 30 40 50 60 pF1KB6 MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLV 190 200 210 220 230 240 250 260 270 280 pF1KB6 PGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK :::::::::::::::::::::::::::::::::::::::::: NP_004 PGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK 250 260 270 280 >>NP_003083 (OMIM: 603520) U2 small nuclear ribonucleopr (225 aa) initn: 634 init1: 597 opt: 614 Z-score: 305.6 bits: 64.1 E(85289): 2.8e-10 Smith-Waterman score: 949; 56.5% identity (72.7% similar) in 278 aa overlap (5-282:2-225) 10 20 30 40 50 60 pF1KB6 MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFK . ::::::::::.:.::::.:::.::::.:::::...::.. ...::::::::::: NP_003 MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFK 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 EVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPA :..:.:::::..:::::: :::::::::::::::.::.:::.....:.::.: :. : : NP_003 ELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 TKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQI : . : .:: . .:: . : : :. NP_003 TTTNKKPGQGTPNSANTQG----------------------------NSTPNP-----QV 120 130 140 190 200 210 220 230 240 pF1KB6 PPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLV : . :::.::::.::::::::.:::::::::::::::::: NP_003 P---------------------DYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLV 150 160 170 180 250 260 270 280 pF1KB6 PGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK :::::::::::.:. ::::::::::::::: ..::::..::: NP_003 PGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK 190 200 210 220 >>NP_937863 (OMIM: 603520) U2 small nuclear ribonucleopr (225 aa) initn: 634 init1: 597 opt: 614 Z-score: 305.6 bits: 64.1 E(85289): 2.8e-10 Smith-Waterman score: 949; 56.5% identity (72.7% similar) in 278 aa overlap (5-282:2-225) 10 20 30 40 50 60 pF1KB6 MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFK . ::::::::::.:.::::.:::.::::.:::::...::.. ...::::::::::: NP_937 MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFK 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 EVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPA :..:.:::::..:::::: :::::::::::::::.::.:::.....:.::.: :. : : NP_937 ELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 TKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQI : . : .:: . .:: . : : :. NP_937 TTTNKKPGQGTPNSANTQG----------------------------NSTPNP-----QV 120 130 140 190 200 210 220 230 240 pF1KB6 PPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLV : . :::.::::.::::::::.:::::::::::::::::: NP_937 P---------------------DYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLV 150 160 170 180 250 260 270 280 pF1KB6 PGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK :::::::::::.:. ::::::::::::::: ..::::..::: NP_937 PGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK 190 200 210 220 282 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:30:16 2016 done: Fri Nov 4 20:30:17 2016 Total Scan time: 7.150 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]