FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6327, 261 aa 1>>>pF1KB6327 261 - 261 aa - 261 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6997+/-0.000418; mu= 7.2380+/- 0.026 mean_var=324.6228+/-70.262, 0's: 0 Z-trim(120.4): 234 B-trim: 0 in 0/56 Lambda= 0.071184 statistics sampled from 35378 (35705) to 35378 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.419), width: 16 Scan time: 7.350 The best scores are: opt bits E(85289) NP_006139 (OMIM: 602920) LIM and SH3 domain protei ( 261) 1822 200.1 3.3e-51 NP_001258537 (OMIM: 602920) LIM and SH3 domain pro ( 205) 1224 138.5 9e-33 NP_998734 (OMIM: 605491) nebulette isoform 2 [Homo ( 270) 1102 126.2 6.2e-29 NP_001166955 (OMIM: 605491) nebulette isoform 3 [H ( 224) 818 96.9 3.4e-20 XP_005252400 (OMIM: 605491) PREDICTED: nebulette i ( 933) 501 65.3 4.6e-10 XP_005252399 (OMIM: 605491) PREDICTED: nebulette i ( 980) 367 51.6 6.6e-06 XP_016870957 (OMIM: 605491) PREDICTED: nebulette i ( 998) 367 51.6 6.7e-06 XP_011517593 (OMIM: 605491) PREDICTED: nebulette i ( 998) 367 51.6 6.7e-06 XP_016870956 (OMIM: 605491) PREDICTED: nebulette i ( 998) 367 51.6 6.7e-06 NP_006384 (OMIM: 605491) nebulette isoform 1 [Homo (1014) 367 51.6 6.7e-06 XP_005269924 (OMIM: 602873) PREDICTED: nebulin-rel (1627) 351 50.2 2.7e-05 NP_001309874 (OMIM: 602873) nebulin-related-anchor (1694) 351 50.3 2.8e-05 XP_011538134 (OMIM: 602873) PREDICTED: nebulin-rel (1695) 351 50.3 2.8e-05 XP_005269922 (OMIM: 602873) PREDICTED: nebulin-rel (1695) 351 50.3 2.8e-05 NP_006166 (OMIM: 602873) nebulin-related-anchoring (1695) 351 50.3 2.8e-05 XP_005269921 (OMIM: 602873) PREDICTED: nebulin-rel (1696) 351 50.3 2.8e-05 XP_006717933 (OMIM: 602873) PREDICTED: nebulin-rel (1696) 351 50.3 2.8e-05 NP_932326 (OMIM: 602873) nebulin-related-anchoring (1730) 351 50.3 2.8e-05 NP_001248392 (OMIM: 602873) nebulin-related-anchor (1731) 351 50.3 2.8e-05 NP_004534 (OMIM: 161650,256030) nebulin isoform 3 (6669) 342 50.2 0.00011 XP_011509529 (OMIM: 161650,256030) PREDICTED: nebu (7067) 342 50.3 0.00012 XP_005246674 (OMIM: 161650,256030) PREDICTED: nebu (7553) 342 50.3 0.00012 XP_011509528 (OMIM: 161650,256030) PREDICTED: nebu (7796) 342 50.3 0.00012 XP_016859674 (OMIM: 161650,256030) PREDICTED: nebu (8184) 342 50.4 0.00013 XP_011509527 (OMIM: 161650,256030) PREDICTED: nebu (8277) 342 50.4 0.00013 XP_016859673 (OMIM: 161650,256030) PREDICTED: nebu (8277) 342 50.4 0.00013 XP_005246672 (OMIM: 161650,256030) PREDICTED: nebu (8277) 342 50.4 0.00013 XP_016859672 (OMIM: 161650,256030) PREDICTED: nebu (8277) 342 50.4 0.00013 XP_005246670 (OMIM: 161650,256030) PREDICTED: nebu (8282) 342 50.4 0.00013 XP_005246669 (OMIM: 161650,256030) PREDICTED: nebu (8282) 342 50.4 0.00013 XP_005246668 (OMIM: 161650,256030) PREDICTED: nebu (8308) 342 50.4 0.00013 XP_016859671 (OMIM: 161650,256030) PREDICTED: nebu (8308) 342 50.4 0.00013 XP_005246667 (OMIM: 161650,256030) PREDICTED: nebu (8308) 342 50.4 0.00013 XP_005246665 (OMIM: 161650,256030) PREDICTED: nebu (8339) 342 50.4 0.00013 XP_016859670 (OMIM: 161650,256030) PREDICTED: nebu (8339) 342 50.4 0.00013 XP_016859668 (OMIM: 161650,256030) PREDICTED: nebu (8370) 342 50.4 0.00013 XP_016859669 (OMIM: 161650,256030) PREDICTED: nebu (8370) 342 50.4 0.00013 XP_005246661 (OMIM: 161650,256030) PREDICTED: nebu (8370) 342 50.4 0.00013 XP_006712604 (OMIM: 161650,256030) PREDICTED: nebu (8370) 342 50.4 0.00013 XP_005246663 (OMIM: 161650,256030) PREDICTED: nebu (8370) 342 50.4 0.00013 XP_005246660 (OMIM: 161650,256030) PREDICTED: nebu (8370) 342 50.4 0.00013 XP_006712605 (OMIM: 161650,256030) PREDICTED: nebu (8370) 342 50.4 0.00013 XP_005246658 (OMIM: 161650,256030) PREDICTED: nebu (8401) 342 50.4 0.00013 XP_005246659 (OMIM: 161650,256030) PREDICTED: nebu (8401) 342 50.4 0.00013 XP_005246657 (OMIM: 161650,256030) PREDICTED: nebu (8432) 342 50.4 0.00013 XP_005246656 (OMIM: 161650,256030) PREDICTED: nebu (8432) 342 50.4 0.00013 XP_005246655 (OMIM: 161650,256030) PREDICTED: nebu (8463) 342 50.4 0.00013 XP_005246653 (OMIM: 161650,256030) PREDICTED: nebu (8463) 342 50.4 0.00013 XP_016859667 (OMIM: 161650,256030) PREDICTED: nebu (8463) 342 50.4 0.00013 XP_005246654 (OMIM: 161650,256030) PREDICTED: nebu (8463) 342 50.4 0.00013 >>NP_006139 (OMIM: 602920) LIM and SH3 domain protein 1 (261 aa) initn: 1822 init1: 1822 opt: 1822 Z-score: 1040.2 bits: 200.1 E(85289): 3.3e-51 Smith-Waterman score: 1822; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261) 10 20 30 40 50 60 pF1KB6 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM 190 200 210 220 230 240 250 260 pF1KB6 YGTVERTGDTGMLPANYVEAI ::::::::::::::::::::: NP_006 YGTVERTGDTGMLPANYVEAI 250 260 >>NP_001258537 (OMIM: 602920) LIM and SH3 domain protein (205 aa) initn: 1218 init1: 1218 opt: 1224 Z-score: 709.4 bits: 138.5 E(85289): 9e-33 Smith-Waterman score: 1224; 96.3% identity (98.9% similar) in 188 aa overlap (74-261:19-205) 50 60 70 80 90 100 pF1KB6 YKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVAD :.... :: .:::::::::::::::::::: NP_001 MLPLRDLQDDTEHEELQGLREEALLQ-RVRYKEEFEKNKGKGFSVVAD 10 20 30 40 110 120 130 140 150 160 pF1KB6 TPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHH 50 60 70 80 90 100 170 180 190 200 210 220 pF1KB6 IPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSF 110 120 130 140 150 160 230 240 250 260 pF1KB6 QDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI :::::::::::::::::::::::::::::::::::::: NP_001 QDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 170 180 190 200 >>NP_998734 (OMIM: 605491) nebulette isoform 2 [Homo sap (270 aa) initn: 1153 init1: 813 opt: 1102 Z-score: 640.5 bits: 126.2 E(85289): 6.2e-29 Smith-Waterman score: 1130; 62.8% identity (81.2% similar) in 277 aa overlap (1-261:1-269) 10 20 30 40 50 60 pF1KB6 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ :::.::::::.::::::::::::.:::.:::::.:::.:::.:::::::::::::::::: NP_998 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI ::: ::::::::::::::::::::.::..::..::.:::.:.:::::::.:.::.::::. NP_998 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 70 80 90 100 110 120 130 140 150 160 pF1KB6 KYHEEFEKSRMGPSGGEGMEPE---------RRDSQ--DGSSYR--RP--LEQQQPHHIP ::::.:::.. :.:. : :...: . ..:. .: .:... : NP_998 KYHEDFEKTK-----GRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGII 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 TSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR-YRAVYDYSAADEDEVSFQ . ::: :: .:.:: ... . :: .:: . . : :::.::::: :::::::. NP_998 V-APVLPGAYQQSHSQGYGYMHQTS--VSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFR 180 190 200 210 220 230 230 240 250 260 pF1KB6 DGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI ::: ::::: ::::::::::.::: ::::::::.: . NP_998 DGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN 240 250 260 270 >>NP_001166955 (OMIM: 605491) nebulette isoform 3 [Homo (224 aa) initn: 846 init1: 813 opt: 818 Z-score: 483.7 bits: 96.9 E(85289): 3.4e-20 Smith-Waterman score: 830; 60.1% identity (80.8% similar) in 213 aa overlap (1-198:1-205) 10 20 30 40 50 60 pF1KB6 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ :::.::::::.::::::::::::.:::.:::::.:::.:::.:::::::::::::::::: NP_001 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI ::: ::::::::::::::::::::.::..::..::.:::.:.:::::::.:.::.::::. NP_001 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 70 80 90 100 110 120 130 140 150 160 pF1KB6 KYHEEFEKSRMGPSGGEGMEPE---------RRDSQ--DGSSYR--RP--LEQQQPHHIP ::::.:::.. :.:. : :...: . ..:. .: .:... : NP_001 KYHEDFEKTK-----GRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGII 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 TSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQD . ::: :: .:.:: ... . :: .:: NP_001 V-APVLPGAYQQSHSQGYGYMHQTS--VSSMRSMQHSPNLDLPSHVRLQCPG 180 190 200 210 220 230 240 250 260 pF1KB6 GDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI >>XP_005252400 (OMIM: 605491) PREDICTED: nebulette isofo (933 aa) initn: 561 init1: 321 opt: 501 Z-score: 301.6 bits: 65.3 E(85289): 4.6e-10 Smith-Waterman score: 506; 42.4% identity (67.5% similar) in 231 aa overlap (49-261:711-932) 20 30 40 50 60 70 pF1KB6 NCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ--SFTMVADTPENLRLKQ .: :..: : : .. ::: :.:. XP_005 EQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKK 690 700 710 720 730 740 80 90 100 110 120 130 pF1KB6 QSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGG ..: :.:.: .. .. ::. :.. ::: ....:..:..:: .::::.:::.. : XP_005 NQENISSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKYHEDFEKTK-----G 750 760 770 780 790 140 150 160 170 180 pF1KB6 EGMEPE---------RRDSQ--DGSSYR--RP--LEQQQPHHIPTSAPVYQQPQQQPVAQ .:. : :...: . ..:. .: .:... : ::: :: .: XP_005 RGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGI-IVAPVLPGAYQQSHSQ 800 810 820 830 840 850 190 200 210 220 230 240 pF1KB6 SYGGYKEPAAPVSIQRSAPGGGGKR-YRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM .:: ... . :: .:: . . : :::.::::: :::::::.::: ::::: :::::: XP_005 GYGYMHQTS--VSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWM 860 870 880 890 900 910 250 260 pF1KB6 YGTVERTGDTGMLPANYVEAI ::::.::: ::::::::.: . XP_005 YGTVQRTGRTGMLPANYIEFVN 920 930 >>XP_005252399 (OMIM: 605491) PREDICTED: nebulette isofo (980 aa) initn: 663 init1: 321 opt: 367 Z-score: 227.0 bits: 51.6 E(85289): 6.6e-06 Smith-Waterman score: 425; 35.1% identity (55.8% similar) in 276 aa overlap (42-261:706-979) 20 30 40 50 60 70 pF1KB6 VYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYP-KQSFTMVADTPE :: .. . : . : : ... ::: XP_005 NQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPA 680 690 700 710 720 730 80 90 100 110 120 pF1KB6 NLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HE--- ..:. .. :.:.:.:.:::.::.::. :.: : .:..:. . .:. : : XP_005 MRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIV 740 750 760 770 780 790 130 140 150 160 pF1KB6 EFEKS----------RMGPSGGEGMEP-----ERRD----SQDGSSYRRPLEQQQPHHI- :... : :.. ..: . :. :. .: ::: ... XP_005 EMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSRSLHMLSEKASHYRRHWSRSHSSSTF 800 810 820 830 840 850 170 180 190 pF1KB6 --------------------------PTS--APVYQQPQQQPVAQSYGGYKEPAAPVSIQ :.. ::: :: .:.:: ... . :: . XP_005 GTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVLPGAYQQSHSQGYGYMHQTS--VSSM 860 870 880 890 900 910 200 210 220 230 240 250 pF1KB6 RSAPGGGGKR-YRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPA :: . . : :::.::::: :::::::.::: ::::: ::::::::::.::: :::::: XP_005 RSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPA 920 930 940 950 960 970 260 pF1KB6 NYVEAI ::.: . XP_005 NYIEFVN 980 >>XP_016870957 (OMIM: 605491) PREDICTED: nebulette isofo (998 aa) initn: 663 init1: 321 opt: 367 Z-score: 227.0 bits: 51.6 E(85289): 6.7e-06 Smith-Waterman score: 425; 35.1% identity (55.8% similar) in 276 aa overlap (42-261:724-997) 20 30 40 50 60 70 pF1KB6 VYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYP-KQSFTMVADTPE :: .. . : . : : ... ::: XP_016 NQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPA 700 710 720 730 740 750 80 90 100 110 120 pF1KB6 NLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HE--- ..:. .. :.:.:.:.:::.::.::. :.: : .:..:. . .:. : : XP_016 MRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIV 760 770 780 790 800 810 130 140 150 160 pF1KB6 EFEKS----------RMGPSGGEGMEP-----ERRD----SQDGSSYRRPLEQQQPHHI- :... : :.. ..: . :. :. .: ::: ... XP_016 EMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSRSLHMLSEKASHYRRHWSRSHSSSTF 820 830 840 850 860 870 170 180 190 pF1KB6 --------------------------PTS--APVYQQPQQQPVAQSYGGYKEPAAPVSIQ :.. ::: :: .:.:: ... . :: . XP_016 GTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVLPGAYQQSHSQGYGYMHQTS--VSSM 880 890 900 910 920 930 200 210 220 230 240 250 pF1KB6 RSAPGGGGKR-YRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPA :: . . : :::.::::: :::::::.::: ::::: ::::::::::.::: :::::: XP_016 RSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPA 940 950 960 970 980 990 260 pF1KB6 NYVEAI ::.: . XP_016 NYIEFVN >>XP_011517593 (OMIM: 605491) PREDICTED: nebulette isofo (998 aa) initn: 663 init1: 321 opt: 367 Z-score: 227.0 bits: 51.6 E(85289): 6.7e-06 Smith-Waterman score: 425; 35.1% identity (55.8% similar) in 276 aa overlap (42-261:724-997) 20 30 40 50 60 70 pF1KB6 VYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYP-KQSFTMVADTPE :: .. . : . : : ... ::: XP_011 NQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPA 700 710 720 730 740 750 80 90 100 110 120 pF1KB6 NLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HE--- ..:. .. :.:.:.:.:::.::.::. :.: : .:..:. . .:. : : XP_011 MRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIV 760 770 780 790 800 810 130 140 150 160 pF1KB6 EFEKS----------RMGPSGGEGMEP-----ERRD----SQDGSSYRRPLEQQQPHHI- :... : :.. ..: . :. :. .: ::: ... XP_011 EMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSRSLHMLSEKASHYRRHWSRSHSSSTF 820 830 840 850 860 870 170 180 190 pF1KB6 --------------------------PTS--APVYQQPQQQPVAQSYGGYKEPAAPVSIQ :.. ::: :: .:.:: ... . :: . XP_011 GTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVLPGAYQQSHSQGYGYMHQTS--VSSM 880 890 900 910 920 930 200 210 220 230 240 250 pF1KB6 RSAPGGGGKR-YRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPA :: . . : :::.::::: :::::::.::: ::::: ::::::::::.::: :::::: XP_011 RSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPA 940 950 960 970 980 990 260 pF1KB6 NYVEAI ::.: . XP_011 NYIEFVN >>XP_016870956 (OMIM: 605491) PREDICTED: nebulette isofo (998 aa) initn: 663 init1: 321 opt: 367 Z-score: 227.0 bits: 51.6 E(85289): 6.7e-06 Smith-Waterman score: 425; 35.1% identity (55.8% similar) in 276 aa overlap (42-261:724-997) 20 30 40 50 60 70 pF1KB6 VYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYP-KQSFTMVADTPE :: .. . : . : : ... ::: XP_016 NQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPA 700 710 720 730 740 750 80 90 100 110 120 pF1KB6 NLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HE--- ..:. .. :.:.:.:.:::.::.::. :.: : .:..:. . .:. : : XP_016 MRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIV 760 770 780 790 800 810 130 140 150 160 pF1KB6 EFEKS----------RMGPSGGEGMEP-----ERRD----SQDGSSYRRPLEQQQPHHI- :... : :.. ..: . :. :. .: ::: ... XP_016 EMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSRSLHMLSEKASHYRRHWSRSHSSSTF 820 830 840 850 860 870 170 180 190 pF1KB6 --------------------------PTS--APVYQQPQQQPVAQSYGGYKEPAAPVSIQ :.. ::: :: .:.:: ... . :: . XP_016 GTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVLPGAYQQSHSQGYGYMHQTS--VSSM 880 890 900 910 920 930 200 210 220 230 240 250 pF1KB6 RSAPGGGGKR-YRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPA :: . . : :::.::::: :::::::.::: ::::: ::::::::::.::: :::::: XP_016 RSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPA 940 950 960 970 980 990 260 pF1KB6 NYVEAI ::.: . XP_016 NYIEFVN >>NP_006384 (OMIM: 605491) nebulette isoform 1 [Homo sap (1014 aa) initn: 663 init1: 321 opt: 367 Z-score: 226.9 bits: 51.6 E(85289): 6.7e-06 Smith-Waterman score: 425; 35.1% identity (55.8% similar) in 276 aa overlap (42-261:740-1013) 20 30 40 50 60 70 pF1KB6 VYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYP-KQSFTMVADTPE :: .. . : . : : ... ::: NP_006 NQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPA 710 720 730 740 750 760 80 90 100 110 120 pF1KB6 NLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HE--- ..:. .. :.:.:.:.:::.::.::. :.: : .:..:. . .:. : : NP_006 MRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIV 770 780 790 800 810 820 130 140 150 160 pF1KB6 EFEKS----------RMGPSGGEGMEP-----ERRD----SQDGSSYRRPLEQQQPHHI- :... : :.. ..: . :. :. .: ::: ... NP_006 EMDRRPGIIVDLKVWRTDPGSIFDLDPLEDNIQSRSLHMLSEKASHYRRHWSRSHSSSTF 830 840 850 860 870 880 170 180 190 pF1KB6 --------------------------PTS--APVYQQPQQQPVAQSYGGYKEPAAPVSIQ :.. ::: :: .:.:: ... . :: . NP_006 GTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAPVLPGAYQQSHSQGYGYMHQTS--VSSM 890 900 910 920 930 940 200 210 220 230 240 250 pF1KB6 RSAPGGGGKR-YRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPA :: . . : :::.::::: :::::::.::: ::::: ::::::::::.::: :::::: NP_006 RSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPA 950 960 970 980 990 1000 260 pF1KB6 NYVEAI ::.: . NP_006 NYIEFVN 1010 261 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:30:50 2016 done: Fri Nov 4 20:30:51 2016 Total Scan time: 7.350 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]