FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6329, 261 aa 1>>>pF1KB6329 261 - 261 aa - 261 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0222+/-0.000699; mu= 16.3821+/- 0.042 mean_var=60.5207+/-12.229, 0's: 0 Z-trim(108.7): 14 B-trim: 6 in 1/47 Lambda= 0.164863 statistics sampled from 10384 (10396) to 10384 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.319), width: 16 Scan time: 2.050 The best scores are: opt bits E(32554) CCDS2416.1 CTDSP1 gene_id:58190|Hs108|chr2 ( 261) 1765 427.8 3.7e-120 CCDS56166.1 CTDSP1 gene_id:58190|Hs108|chr2 ( 260) 1630 395.7 1.7e-110 CCDS33735.1 CTDSPL gene_id:10217|Hs108|chr3 ( 265) 1203 294.1 6.5e-80 CCDS33734.1 CTDSPL gene_id:10217|Hs108|chr3 ( 276) 1048 257.3 8.4e-69 CCDS41801.1 CTDSP2 gene_id:10106|Hs108|chr12 ( 271) 981 241.3 5.2e-64 CCDS10110.1 CTDSPL2 gene_id:51496|Hs108|chr15 ( 466) 508 129.0 6e-30 CCDS11093.1 CTDNEP1 gene_id:23399|Hs108|chr17 ( 244) 432 110.7 9.7e-25 CCDS33023.1 TIMM50 gene_id:92609|Hs108|chr19 ( 456) 268 71.9 9e-13 >>CCDS2416.1 CTDSP1 gene_id:58190|Hs108|chr2 (261 aa) initn: 1765 init1: 1765 opt: 1765 Z-score: 2270.7 bits: 427.8 E(32554): 3.7e-120 Smith-Waterman score: 1765; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261) 10 20 30 40 50 60 pF1KB6 MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 PLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 DGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 DGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 CVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 CVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPF 190 200 210 220 230 240 250 260 pF1KB6 FEQLSRVDDVYSVLRQPRPGS ::::::::::::::::::::: CCDS24 FEQLSRVDDVYSVLRQPRPGS 250 260 >>CCDS56166.1 CTDSP1 gene_id:58190|Hs108|chr2 (260 aa) initn: 1275 init1: 1275 opt: 1630 Z-score: 2097.2 bits: 395.7 E(32554): 1.7e-110 Smith-Waterman score: 1630; 96.8% identity (98.0% similar) in 251 aa overlap (12-261:11-260) 10 20 30 40 50 pF1KB6 MDSSAVITQISKEEARGPLRG-KGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSG .::.:: : .::::::::::::::::::::::::::::::::::::: CCDS56 MVAAPWATQEQEEGRGIQPGDRGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSG 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 APLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVE ::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: CCDS56 APLLVEENGAIPK-TPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 IDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 IDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 SCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLP 180 190 200 210 220 230 240 250 260 pF1KB6 FFEQLSRVDDVYSVLRQPRPGS :::::::::::::::::::::: CCDS56 FFEQLSRVDDVYSVLRQPRPGS 240 250 260 >>CCDS33735.1 CTDSPL gene_id:10217|Hs108|chr3 (265 aa) initn: 1185 init1: 1034 opt: 1203 Z-score: 1548.2 bits: 294.1 E(32554): 6.5e-80 Smith-Waterman score: 1203; 70.0% identity (85.6% similar) in 263 aa overlap (1-256:1-261) 10 20 30 40 50 pF1KB6 MDSSAVITQISK-EEARGPLRGKGDQKSAAS---QKPRSRGILHSLFCCVCRD-DGEALP ::. :.:::... .: .: : : :.. : . .: :::.:: :.::: :: . :: : CCDS33 MDGPAIITQVTNPKEDEGRLPGAGEKASQCNVSLKKQRSRSILSSFFCCF-RDYNVEAPP 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 AHSGA--PLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNAD : . : ::::::.. : :..:::::. . : : :::::::::::::::::..::: CCDS33 PSSPSVLPPLVEENGGLQKP-PAKYLLPEVTVLDYGKKCVVIDLDETLVHSSFKPISNAD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 FIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFR ::.::::::..:::::::::::::::::::.:::::::::::::::::::::::.::.:: CCDS33 FIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLDRWGVFR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 ARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTE ::::::::::::::::::::::::.: .:.:.:::::::.:::.::::: ::::.:.::: CCDS33 ARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTE 180 190 200 210 220 230 240 250 260 pF1KB6 LHDLLPFFEQLSRVDDVYSVLRQPRPGS : ::.:::: ::: :::::.:.. CCDS33 LLDLIPFFEGLSREDDVYSMLHRLCNR 240 250 260 >>CCDS33734.1 CTDSPL gene_id:10217|Hs108|chr3 (276 aa) initn: 1185 init1: 1034 opt: 1048 Z-score: 1348.7 bits: 257.3 E(32554): 8.4e-69 Smith-Waterman score: 1185; 67.4% identity (82.8% similar) in 273 aa overlap (1-256:1-272) 10 20 30 40 50 pF1KB6 MDSSAVITQISK-EEARGPLRGKGDQKSAAS---QKPRSRGILHSLFCCVCRD-DGEALP ::. :.:::... .: .: : : :.. : . .: :::.:: :.::: :: . :: : CCDS33 MDGPAIITQVTNPKEDEGRLPGAGEKASQCNVSLKKQRSRSILSSFFCCF-RDYNVEAPP 10 20 30 40 50 60 70 80 90 100 pF1KB6 AHSGA--PLLVEENGAIPK----------QTPVQYLLPEAKAQDSDKICVVIDLDETLVH : . : ::::::.. : . :..:::::. . : : :::::::::::: CCDS33 PSSPSVLPPLVEENGGLQKGDQRQVIPIPSPPAKYLLPEVTVLDYGKKCVVIDLDETLVH 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 SSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVA :::::..:::::.::::::..:::::::::::::::::::.::::::::::::::::::: CCDS33 SSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVA 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 DLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVA ::::.::.::::::::::::::::::::::::::.: .:.:.:::::::.:::.::::: CCDS33 DLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQ 180 190 200 210 220 230 230 240 250 260 pF1KB6 SWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS ::::.:.:::: ::.:::: ::: :::::.:.. CCDS33 SWFDDMTDTELLDLIPFFEGLSREDDVYSMLHRLCNR 240 250 260 270 >>CCDS41801.1 CTDSP2 gene_id:10106|Hs108|chr12 (271 aa) initn: 1038 init1: 973 opt: 981 Z-score: 1262.7 bits: 241.3 E(32554): 5.2e-64 Smith-Waterman score: 1049; 60.9% identity (80.1% similar) in 271 aa overlap (1-258:1-269) 10 20 30 40 50 pF1KB6 MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCV-CRDDGEALPAHSG :. ...::: .:.: : .: .... .:::.:.:...:::: . :.. . CCDS41 MEHGSIITQARREDAL-VLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTEL 10 20 30 40 50 60 70 80 90 100 pF1KB6 APLLVEENGAIPK------------QTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFK : :: ..: : : : ::::. .:. .::::::::::::::::: CCDS41 AAYK-EEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFK 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 PVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLD :.::::::.:.::.:..:::::::::.:::::.::::::::::::::::::::::.:::: CCDS41 PINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLD 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 KWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFD . :.:::::::::::::.: :::::::::::::..::::::::::.:::.::::: :::: CCDS41 RCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFD 180 190 200 210 220 230 230 240 250 260 pF1KB6 NMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS .:.:::: .:.:.::.:: ..:::. : : : CCDS41 DMADTELLNLIPIFEELSGAEDVYTSLGQLRAP 240 250 260 270 >>CCDS10110.1 CTDSPL2 gene_id:51496|Hs108|chr15 (466 aa) initn: 500 init1: 273 opt: 508 Z-score: 651.2 bits: 129.0 E(32554): 6e-30 Smith-Waterman score: 508; 44.9% identity (75.3% similar) in 178 aa overlap (80-255:278-454) 50 60 70 80 90 100 pF1KB6 DGEALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPV :: :.... .. .:.:::::::: :.. . CCDS10 YEEDWEVFDPYYFIKHVPPLTEEQLNRKPALP-LKTRSTPEFSLVLDLDETLVHCSLNEL 250 260 270 280 290 300 110 120 130 140 150 160 pF1KB6 NNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLD-K ..: . .:: .. :..:::: :: :::.::....: .::::: ::: . ..:: : CCDS10 EDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPK 310 320 330 340 350 360 170 180 190 200 210 220 pF1KB6 WGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDN : ::::: :: .:::.:::. ::::: ...:.:::: ..... .:..:. ::: . CCDS10 KQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMD 370 380 390 400 410 420 230 240 250 260 pF1KB6 MSDTELHDLLPFFEQLSRVD-DVYSVLRQPRPGS .:.:: :.::.:.: ... :: .: CCDS10 KNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD 430 440 450 460 >>CCDS11093.1 CTDNEP1 gene_id:23399|Hs108|chr17 (244 aa) initn: 476 init1: 283 opt: 432 Z-score: 557.7 bits: 110.7 E(32554): 9.7e-25 Smith-Waterman score: 474; 45.3% identity (69.8% similar) in 179 aa overlap (85-254:57-234) 60 70 80 90 100 pF1KB6 PAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHS--------SF :: . :: .:.::::::.:: . CCDS11 LLRRQIRTVIQYQTVRYDILPLSPVSRNRLAQVKRKI-LVLDLDETLIHSHHDGVLRPTV 30 40 50 60 70 80 110 120 130 140 150 160 pF1KB6 KPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLL .: . :::. : :: . .: :::::: ::. ... .: :.::::. :.. ::: : CCDS11 RPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKL 90 100 110 120 130 140 170 180 190 200 210 220 pF1KB6 DK-WGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASW :. . .. : .:. :... :.:.:::: . :: ..::::::..: :::::.:. :: CCDS11 DNSRSILKRRYYRQHCTLELGSYIKDLSVVHSDLSSIVILDNSPGAYRSHPDNAIPIKSW 150 160 170 180 190 200 230 240 250 260 pF1KB6 FDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS :.. ::: : .:::... : . :: ::: CCDS11 FSDPSDTALLNLLPMLDALRFTADVRSVLSRNLHQHRLW 210 220 230 240 >>CCDS33023.1 TIMM50 gene_id:92609|Hs108|chr19 (456 aa) initn: 295 init1: 245 opt: 268 Z-score: 342.8 bits: 71.9 E(32554): 9e-13 Smith-Waterman score: 288; 27.2% identity (55.1% similar) in 265 aa overlap (9-256:139-403) 10 20 30 pF1KB6 MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGI : .. .:: ...: :.. .:. : CCDS33 AVFSRLRSGLRLGSRGLCTRLATPPRRAPDQAAEIGSRGSTKAQGPQQQPGSEGPSYAKK 110 120 130 140 150 160 40 50 60 70 80 90 pF1KB6 LHSLFCCVCRDDGEALPAHSGAPLLVEENGA-IPKQ---TP--VQYLLPEAKAQDSDKIC . . . : . .. . :.:::: :: . : :: : : . . CCDS33 VALWLAGLLGAGGTVSVVYIFGNNPVDENGAKIPDEFDNDPILVQQLRRTYKYFKDYRQM 170 180 190 200 210 220 100 110 120 130 140 pF1KB6 VVIDLDETLVHSSFK-PVNNADFIIPVEIDGVV-HQVYVL-------KRPHVDEFLQRMG .. . :. . .. : . . . .:. ::. : . : ::: .. ..:... CCDS33 IIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLA 230 240 250 260 270 280 150 160 170 180 190 200 pF1KB6 ELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVL :.: :.::. . : :. : .: : . ::::.. . :..:::.: :.:: ::. CCDS33 PLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVV 290 300 310 320 330 340 210 220 230 240 250 260 pF1KB6 ILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQ--LSRVDDVYSVLRQPRPGS ..: . .. ..: :.: . : : .: : :: :.. :. :.:: .::.. CCDS33 VVDCKKEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALED 350 360 370 380 390 400 CCDS33 DPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLGSLTSRLWPRSKQP 410 420 430 440 450 261 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:30:10 2016 done: Sat Nov 5 00:30:10 2016 Total Scan time: 2.050 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]