FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6333, 261 aa 1>>>pF1KB6333 261 - 261 aa - 261 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5817+/-0.000341; mu= 13.3019+/- 0.021 mean_var=71.9945+/-14.347, 0's: 0 Z-trim(116.0): 305 B-trim: 0 in 0/51 Lambda= 0.151156 statistics sampled from 26497 (26817) to 26497 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.314), width: 16 Scan time: 7.010 The best scores are: opt bits E(85289) NP_001639 (OMIM: 176820) prostate-specific antigen ( 261) 1839 409.9 2.3e-114 NP_001025218 (OMIM: 176820) prostate-specific anti ( 238) 1473 330.1 2.3e-90 NP_005542 (OMIM: 147960) kallikrein-2 isoform 1 pr ( 261) 1446 324.2 1.5e-88 NP_002248 (OMIM: 147910,615953) kallikrein-1 prepr ( 262) 1130 255.3 8.2e-68 NP_001002231 (OMIM: 147960) kallikrein-2 isoform 2 ( 223) 1103 249.4 4.2e-66 NP_001025219 (OMIM: 176820) prostate-specific anti ( 218) 1052 238.3 9.2e-63 NP_001243009 (OMIM: 147960) kallikrein-2 isoform 3 ( 159) 930 211.6 7.2e-55 NP_056411 (OMIM: 605505) kallikrein-13 precursor [ ( 277) 772 177.2 2.7e-44 NP_001129504 (OMIM: 604434) kallikrein-11 isoform ( 250) 749 172.2 8e-43 NP_006844 (OMIM: 604434) kallikrein-11 isoform 1 p ( 250) 749 172.2 8e-43 NP_659196 (OMIM: 604434) kallikrein-11 isoform 2 [ ( 282) 749 172.2 8.9e-43 XP_011525244 (OMIM: 147910,615953) PREDICTED: kall ( 160) 715 164.7 9.4e-41 NP_036447 (OMIM: 605504) kallikrein-9 precursor [H ( 250) 707 163.1 4.6e-40 NP_001290343 (OMIM: 167800,601564) trypsin-2 isofo ( 261) 602 140.2 3.7e-33 XP_006723328 (OMIM: 610601) PREDICTED: kallikrein- ( 256) 560 131.0 2.1e-30 NP_059979 (OMIM: 610601) kallikrein-15 isoform 4 p ( 256) 560 131.0 2.1e-30 XP_011524674 (OMIM: 604434) PREDICTED: kallikrein- ( 275) 554 129.7 5.5e-30 XP_011524672 (OMIM: 604434) PREDICTED: kallikrein- ( 275) 554 129.7 5.5e-30 XP_011524675 (OMIM: 604434) PREDICTED: kallikrein- ( 275) 554 129.7 5.5e-30 XP_011524673 (OMIM: 604434) PREDICTED: kallikrein- ( 275) 554 129.7 5.5e-30 NP_001161077 (OMIM: 604434) kallikrein-11 isoform ( 275) 554 129.7 5.5e-30 XP_011524671 (OMIM: 604434) PREDICTED: kallikrein- ( 307) 554 129.7 6e-30 XP_011525387 (OMIM: 610601) PREDICTED: kallikrein- ( 255) 550 128.8 9.5e-30 NP_001264010 (OMIM: 610601) kallikrein-15 isoform ( 255) 550 128.8 9.5e-30 XP_016882482 (OMIM: 602673) PREDICTED: kallikrein- ( 276) 525 123.4 4.4e-28 NP_001070968 (OMIM: 602673) kallikrein-10 prepropr ( 276) 525 123.4 4.4e-28 XP_005259119 (OMIM: 602673) PREDICTED: kallikrein- ( 276) 525 123.4 4.4e-28 XP_005259118 (OMIM: 602673) PREDICTED: kallikrein- ( 276) 525 123.4 4.4e-28 XP_006723352 (OMIM: 602673) PREDICTED: kallikrein- ( 276) 525 123.4 4.4e-28 XP_006723350 (OMIM: 602673) PREDICTED: kallikrein- ( 276) 525 123.4 4.4e-28 NP_002767 (OMIM: 602673) kallikrein-10 preproprote ( 276) 525 123.4 4.4e-28 NP_665895 (OMIM: 602673) kallikrein-10 preproprote ( 276) 525 123.4 4.4e-28 NP_002095 (OMIM: 600784) granzyme K precursor [Hom ( 264) 520 122.3 9.1e-28 NP_006135 (OMIM: 140050) granzyme A precursor [Hom ( 262) 507 119.4 6.4e-27 NP_001304264 (OMIM: 134350,613912) complement fact ( 260) 500 117.9 1.8e-26 NP_001919 (OMIM: 134350,613912) complement factor ( 253) 494 116.6 4.5e-26 NP_001275679 (OMIM: 606751) transmembrane protease ( 413) 496 117.2 5e-26 NP_001275680 (OMIM: 606751) transmembrane protease ( 448) 496 117.2 5.3e-26 NP_110397 (OMIM: 606751) transmembrane protease se ( 457) 496 117.2 5.4e-26 NP_077078 (OMIM: 191081) tryptase beta-2 prepropro ( 275) 492 116.2 6.5e-26 NP_001275930 (OMIM: 206200,609862) transmembrane p ( 802) 495 117.1 1e-25 NP_705837 (OMIM: 206200,609862) transmembrane prot ( 811) 495 117.1 1e-25 NP_002760 (OMIM: 167800,276000,614044) trypsin-1 p ( 247) 487 115.1 1.3e-25 NP_003285 (OMIM: 191080) tryptase alpha/beta-1 pre ( 275) 485 114.7 1.9e-25 XP_011514713 (OMIM: 167800,276000,614044) PREDICTE ( 472) 487 115.2 2.2e-25 NP_001184027 (OMIM: 613578) trypsin-3 isoform 4 pr ( 240) 481 113.8 3e-25 NP_002762 (OMIM: 613578) trypsin-3 isoform 2 prepr ( 247) 481 113.8 3.1e-25 NP_001184026 (OMIM: 613578) trypsin-3 isoform 3 pr ( 261) 481 113.8 3.3e-25 NP_001298111 (OMIM: 606135) kallikrein-14 prepropr ( 267) 481 113.8 3.3e-25 NP_071329 (OMIM: 606135) kallikrein-14 preproprote ( 267) 481 113.8 3.3e-25 >>NP_001639 (OMIM: 176820) prostate-specific antigen iso (261 aa) initn: 1839 init1: 1839 opt: 1839 Z-score: 2174.1 bits: 409.9 E(85289): 2.3e-114 Smith-Waterman score: 1839; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261) 10 20 30 40 50 60 pF1KB6 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 190 200 210 220 230 240 250 260 pF1KB6 SLYTKVVHYRKWIKDTIVANP ::::::::::::::::::::: NP_001 SLYTKVVHYRKWIKDTIVANP 250 260 >>NP_001025218 (OMIM: 176820) prostate-specific antigen (238 aa) initn: 1473 init1: 1473 opt: 1473 Z-score: 1743.4 bits: 330.1 E(85289): 2.3e-90 Smith-Waterman score: 1473; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210) 10 20 30 40 50 60 pF1KB6 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP :::::::::::::::::::::::::::::: NP_001 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSWVILITELTMPALPMVLHGSLVPWRGGV 190 200 210 220 230 >>NP_005542 (OMIM: 147960) kallikrein-2 isoform 1 prepro (261 aa) initn: 1446 init1: 1446 opt: 1446 Z-score: 1710.9 bits: 324.2 E(85289): 1.5e-88 Smith-Waterman score: 1446; 77.0% identity (91.2% similar) in 261 aa overlap (1-261:1-261) 10 20 30 40 50 60 pF1KB6 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV :: :. ..::: ::.::: :::::::::::::::::: : :.: : ::::::::::: NP_005 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD ::::::....: . ::::.::.:::::: ::::::::::.:::::.. ::: .::::: NP_005 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS ::::::::::..::.:::. :::::::::::::::::::::::::: :..::::.::..: NP_005 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP ::.::... .:::.:::::: :::::.::.:::::::::::::::::::: :::::::.: NP_005 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 190 200 210 220 230 240 250 260 pF1KB6 SLYTKVVHYRKWIKDTIVANP ..:::::::::::::::.::: NP_005 AVYTKVVHYRKWIKDTIAANP 250 260 >>NP_002248 (OMIM: 147910,615953) kallikrein-1 prepropro (262 aa) initn: 1126 init1: 611 opt: 1130 Z-score: 1338.5 bits: 255.3 E(85289): 8.2e-68 Smith-Waterman score: 1130; 60.5% identity (80.1% similar) in 261 aa overlap (1-260:1-261) 10 20 30 40 50 60 pF1KB6 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV :: :. :.::. :::: : ::::::::::.::::::. . . :::.::: ::: NP_002 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD ::::::: .. . ::::.:: :.:.: .::.::::: ..::::.:. . .: ::: NP_002 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LMLLRLSEPAE-LTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVI ::::::.:::. .::::::..:::.:: .:.:: ::::::::::.: : ::::::... NP_002 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 SNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPER :: : ..: :::: ::::.:. :::.:: :::::::.:.:::::.:::: ::. :.. NP_002 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 190 200 210 220 230 240 240 250 260 pF1KB6 PSLYTKVVHYRKWIKDTIVANP ::. ..:. : :::.:::. : NP_002 PSVAVRVLSYVKWIEDTIAENS 250 260 >>NP_001002231 (OMIM: 147960) kallikrein-2 isoform 2 pre (223 aa) initn: 1103 init1: 1103 opt: 1103 Z-score: 1307.7 bits: 249.4 E(85289): 4.2e-66 Smith-Waterman score: 1103; 74.2% identity (89.5% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB6 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV :: :. ..::: ::.::: :::::::::::::::::: : :.: : ::::::::::: NP_001 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD ::::::....: . ::::.::.:::::: ::::::::::.:::::.. ::: .::::: NP_001 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS ::::::::::..::.:::. :::::::::::::::::::::::::: :..::::.::..: NP_001 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP ::.::... .:::.:::::: :::::.:: NP_001 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGVSHPYSQHLEGKG 190 200 210 220 >>NP_001025219 (OMIM: 176820) prostate-specific antigen (218 aa) initn: 1527 init1: 1052 opt: 1052 Z-score: 1247.8 bits: 238.3 E(85289): 9.2e-63 Smith-Waterman score: 1445; 83.1% identity (83.5% similar) in 261 aa overlap (1-261:1-218) 10 20 30 40 50 60 pF1KB6 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD :::::::: .:::::::: NP_001 LTAAHCIR-------------------------------------------KPGDDSSHD 70 130 140 150 160 170 180 pF1KB6 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 80 90 100 110 120 130 190 200 210 220 230 240 pF1KB6 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 140 150 160 170 180 190 250 260 pF1KB6 SLYTKVVHYRKWIKDTIVANP ::::::::::::::::::::: NP_001 SLYTKVVHYRKWIKDTIVANP 200 210 >>NP_001243009 (OMIM: 147960) kallikrein-2 isoform 3 [Ho (159 aa) initn: 930 init1: 930 opt: 930 Z-score: 1106.1 bits: 211.6 E(85289): 7.2e-55 Smith-Waterman score: 930; 80.5% identity (95.6% similar) in 159 aa overlap (103-261:1-159) 80 90 100 110 120 130 pF1KB6 ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL :::::.. ::: .:::::::::::::::.. NP_001 MSLLKHQSLRPDEDSSHDLMLLRLSEPAKI 10 20 30 140 150 160 170 180 190 pF1KB6 TDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKV ::.:::. :::::::::::::::::::::::::: :..::::.::..:::.::... .:: NP_001 TDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKV 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 TKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKW :.:::::: :::::.::.:::::::::::::::::::: :::::::.:..:::::::::: NP_001 TEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKW 100 110 120 130 140 150 260 pF1KB6 IKDTIVANP :::::.::: NP_001 IKDTIAANP >>NP_056411 (OMIM: 605505) kallikrein-13 precursor [Homo (277 aa) initn: 847 init1: 442 opt: 772 Z-score: 916.2 bits: 177.2 E(85289): 2.7e-44 Smith-Waterman score: 772; 47.6% identity (70.4% similar) in 233 aa overlap (27-257:38-262) 10 20 30 40 50 pF1KB6 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVH ::. : ::::::. . .:: .::::::: NP_056 IASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCGGVLVH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 PQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGD- :.::::::::... . ::.:.: . : :: .: ::.::: : : : NP_056 PKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRS--------PTHL 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 DSSHDLMLLRLSEPAELTDAVKVMDLPTQEPAL-GTTCYASGWGSIEPEEFLTPKKLQCV . .::.:::.:. :..:: .... : .. :::: .::::. . :: :::. NP_056 NHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 DLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPC .... :.. : ::.: :.: ::::: :::..: :::::::::: .: ::.:::. :: NP_056 NIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPC 180 190 200 210 220 230 240 250 260 pF1KB6 ALPERPSLYTKVVHYRKWIKDTIVANP . :.::..::.: .: ::..:: NP_056 GQPDRPGVYTRVSRYVLWIRETIRKYETQQQKWLKGPQ 240 250 260 270 >>NP_001129504 (OMIM: 604434) kallikrein-11 isoform 1 pr (250 aa) initn: 754 init1: 456 opt: 749 Z-score: 889.8 bits: 172.2 E(85289): 8e-43 Smith-Waterman score: 755; 39.5% identity (71.1% similar) in 256 aa overlap (5-260:6-250) 10 20 30 40 50 pF1KB6 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQW ...:.:.. .:. .::. :.::. ::::::. . . : .::..:. :.: NP_001 MRILQLILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRW 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 VLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSH .::::::.. . .. ::.:.: . : :. ...::::: .. :: :. : . NP_001 LLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRN 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 DLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVI :.::.... :. .: ::. . : .. . ::.: ::::: .. :. :.:... .: NP_001 DIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITII 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 SNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPER .. : ...: ..: :.::. :::..:.:::::::::: :::: :::..:::. .. NP_001 EHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRK 170 180 190 200 210 220 240 250 260 pF1KB6 PSLYTKVVHYRKWIKDTIVANP :..:::: .: ::..:. : NP_001 PGVYTKVCKYVDWIQETMKNN 230 240 250 >>NP_006844 (OMIM: 604434) kallikrein-11 isoform 1 precu (250 aa) initn: 754 init1: 456 opt: 749 Z-score: 889.8 bits: 172.2 E(85289): 8e-43 Smith-Waterman score: 755; 39.5% identity (71.1% similar) in 256 aa overlap (5-260:6-250) 10 20 30 40 50 pF1KB6 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQW ...:.:.. .:. .::. :.::. ::::::. . . : .::..:. :.: NP_006 MRILQLILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRW 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 VLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSH .::::::.. . .. ::.:.: . : :. ...::::: .. :: :. : . NP_006 LLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRN 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 DLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVI :.::.... :. .: ::. . : .. . ::.: ::::: .. :. :.:... .: NP_006 DIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITII 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 SNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPER .. : ...: ..: :.::. :::..:.:::::::::: :::: :::..:::. .. NP_006 EHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRK 170 180 190 200 210 220 240 250 260 pF1KB6 PSLYTKVVHYRKWIKDTIVANP :..:::: .: ::..:. : NP_006 PGVYTKVCKYVDWIQETMKNN 230 240 250 261 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:42:38 2016 done: Fri Nov 4 22:42:39 2016 Total Scan time: 7.010 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]