FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6337, 262 aa 1>>>pF1KB6337 262 - 262 aa - 262 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2969+/-0.000837; mu= 14.5487+/- 0.050 mean_var=66.5419+/-13.850, 0's: 0 Z-trim(106.8): 164 B-trim: 33 in 1/48 Lambda= 0.157227 statistics sampled from 9029 (9205) to 9029 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.283), width: 16 Scan time: 2.280 The best scores are: opt bits E(32554) CCDS3965.1 GZMA gene_id:3001|Hs108|chr5 ( 262) 1777 411.8 2.4e-115 CCDS3964.1 GZMK gene_id:3003|Hs108|chr5 ( 264) 722 172.5 2.7e-43 CCDS12046.1 CFD gene_id:1675|Hs108|chr19 ( 253) 621 149.6 2e-36 CCDS82261.1 CFD gene_id:1675|Hs108|chr19 ( 260) 621 149.6 2.1e-36 CCDS9633.1 GZMB gene_id:3002|Hs108|chr14 ( 247) 582 140.7 9.1e-34 CCDS9632.1 GZMH gene_id:2999|Hs108|chr14 ( 246) 567 137.3 9.6e-33 CCDS12823.2 KLK14 gene_id:43847|Hs108|chr19 ( 267) 559 135.5 3.6e-32 CCDS12813.1 KLK8 gene_id:11202|Hs108|chr19 ( 260) 539 131.0 8.2e-31 CCDS42600.1 KLK8 gene_id:11202|Hs108|chr19 ( 305) 539 131.0 9.4e-31 CCDS9630.1 CMA1 gene_id:1215|Hs108|chr14 ( 247) 528 128.5 4.4e-30 CCDS12807.1 KLK3 gene_id:354|Hs108|chr19 ( 261) 507 123.7 1.3e-28 CCDS5872.1 PRSS1 gene_id:5644|Hs108|chr7 ( 247) 504 123.0 1.9e-28 CCDS12822.1 KLK13 gene_id:26085|Hs108|chr19 ( 277) 504 123.1 2.1e-28 CCDS12821.1 KLK12 gene_id:43849|Hs108|chr19 ( 248) 499 121.9 4.2e-28 CCDS9631.1 CTSG gene_id:1511|Hs108|chr14 ( 255) 499 121.9 4.3e-28 CCDS12819.1 KLK11 gene_id:11012|Hs108|chr19 ( 250) 494 120.8 9.4e-28 CCDS12818.1 KLK11 gene_id:11012|Hs108|chr19 ( 282) 494 120.8 1e-27 CCDS12031.1 GZMM gene_id:3004|Hs108|chr19 ( 257) 493 120.6 1.1e-27 CCDS77203.1 PRSS57 gene_id:400668|Hs108|chr19 ( 282) 492 120.3 1.4e-27 CCDS12811.1 KLK6 gene_id:5653|Hs108|chr19 ( 244) 486 119.0 3.2e-27 CCDS62766.1 KLK15 gene_id:55554|Hs108|chr19 ( 255) 485 118.7 3.9e-27 CCDS12805.1 KLK15 gene_id:55554|Hs108|chr19 ( 256) 485 118.7 3.9e-27 CCDS12041.1 PRSS57 gene_id:400668|Hs108|chr19 ( 283) 485 118.8 4.3e-27 CCDS12804.1 KLK1 gene_id:3816|Hs108|chr19 ( 262) 481 117.8 7.5e-27 CCDS12808.1 KLK2 gene_id:3817|Hs108|chr19 ( 261) 479 117.4 1e-26 CCDS12809.1 KLK4 gene_id:9622|Hs108|chr19 ( 254) 477 116.9 1.4e-26 CCDS12820.1 KLK12 gene_id:43849|Hs108|chr19 ( 254) 476 116.7 1.6e-26 CCDS12816.1 KLK9 gene_id:284366|Hs108|chr19 ( 250) 470 115.3 4.1e-26 CCDS56571.1 PRSS3 gene_id:5646|Hs108|chr9 ( 261) 469 115.1 5e-26 CCDS6545.1 PRSS3 gene_id:5646|Hs108|chr9 ( 247) 467 114.6 6.5e-26 CCDS56570.1 PRSS3 gene_id:5646|Hs108|chr9 ( 240) 463 113.7 1.2e-25 CCDS47958.1 PRSS3 gene_id:5646|Hs108|chr9 ( 304) 463 113.8 1.4e-25 CCDS13571.1 TMPRSS15 gene_id:5651|Hs108|chr21 (1019) 466 114.8 2.5e-25 CCDS45469.1 PRSS8 gene_id:5652|Hs108|chr16 ( 343) 460 113.1 2.6e-25 CCDS83236.1 PRSS2 gene_id:5645|Hs108|chr7 ( 247) 457 112.4 3.1e-25 CCDS74669.1 PRSS56 gene_id:646960|Hs108|chr2 ( 603) 456 112.4 7.7e-25 CCDS8812.1 CELA1 gene_id:1990|Hs108|chr12 ( 258) 446 109.9 1.8e-24 CCDS3518.1 TMPRSS11D gene_id:9407|Hs108|chr4 ( 418) 447 110.2 2.3e-24 CCDS73391.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 413) 445 109.8 3.2e-24 CCDS73392.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 448) 445 109.8 3.4e-24 CCDS44735.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 457) 445 109.8 3.4e-24 CCDS53579.1 HABP2 gene_id:3026|Hs108|chr10 ( 534) 443 109.4 5.4e-24 CCDS32490.1 CTRB1 gene_id:1504|Hs108|chr16 ( 263) 439 108.3 5.6e-24 CCDS7577.1 HABP2 gene_id:3026|Hs108|chr10 ( 560) 443 109.4 5.6e-24 CCDS12810.1 KLK5 gene_id:25818|Hs108|chr19 ( 293) 438 108.1 7.1e-24 CCDS55788.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 532) 439 108.5 1e-23 CCDS41721.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 567) 439 108.5 1.1e-23 CCDS83235.1 PRSS2 gene_id:5645|Hs108|chr7 ( 261) 432 106.7 1.7e-23 CCDS58185.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 563) 436 107.8 1.7e-23 CCDS3369.1 HGFAC gene_id:3083|Hs108|chr4 ( 655) 436 107.9 1.9e-23 >>CCDS3965.1 GZMA gene_id:3001|Hs108|chr5 (262 aa) initn: 1777 init1: 1777 opt: 1777 Z-score: 2184.3 bits: 411.8 E(32554): 2.4e-115 Smith-Waterman score: 1777; 99.6% identity (99.6% similar) in 262 aa overlap (1-262:1-262) 10 20 30 40 50 60 pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 KDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 MEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS39 DRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGP 190 200 210 220 230 240 250 260 pF1KB6 GVYILLSKKHLNWIIMTIKGAV :::::::::::::::::::::: CCDS39 GVYILLSKKHLNWIIMTIKGAV 250 260 >>CCDS3964.1 GZMK gene_id:3003|Hs108|chr5 (264 aa) initn: 646 init1: 405 opt: 722 Z-score: 890.9 bits: 172.5 E(32554): 2.7e-43 Smith-Waterman score: 722; 45.1% identity (73.8% similar) in 237 aa overlap (25-254:21-254) 10 20 30 40 50 pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVC--EKIIGGNEVTPHSRPYMVLLSLDRKTICAGAL :: .::::.::.:::::.:. .. . .:.:.: CCDS39 MTKFSSFSLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVL 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 IAKDWVLTAAHCNL----NKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGD : .::::::::. .. :.:::::....: .:: . .:: .:. . .: CCDS39 IDPQWVLTAAHCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSND 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTH-NSASWSDTLREVNITI . :..: ::.::.: .::. .: ... :: :.:.::: : .: :::::::..:. CCDS39 IMLVKLQTAAKLNKHVKMLHIRSK-TSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 IDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENK ..::.::....:: .: : .:::::. .: .:::.::::.::.:.:::....: : : CCDS39 LSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHE-- 180 190 200 210 220 230 240 250 260 pF1KB6 CGDPRGPGVYILLSKKHLNWIIMTIKGAV :: ::.: ::.::. .:: CCDS39 CGVATKPGIYTLLTKKYQTWIKSNLVPPHTN 240 250 260 >>CCDS12046.1 CFD gene_id:1675|Hs108|chr19 (253 aa) initn: 613 init1: 313 opt: 621 Z-score: 767.4 bits: 149.6 E(32554): 2e-36 Smith-Waterman score: 621; 41.3% identity (70.4% similar) in 230 aa overlap (28-254:25-248) 10 20 30 40 50 60 pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIA .:.:: :. :.::::. ..:. .:.:.:.: CCDS12 MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVA 10 20 30 40 50 70 80 90 100 110 pF1KB6 KDWVLTAAHC---NLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKL ..:::.:::: . . ::.:::::... ::.:... : . :.: .: : . :: : CCDS12 EQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRK :::.::: .. : : . :: :::.:.::::: ..... :.:..: . ..:: CCDS12 LQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 VCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDP .:: :.:. . .: ..:: : : ::::.::::.::.: ::..::.. : ::. CCDS12 TCNRRTHH--DGAITERLMCAESNR--RDSCKGDSGGPLVCGGVLEGVVTSG-SRVCGNR 180 190 200 210 220 230 240 250 260 pF1KB6 RGPGVYILLSKKHLNWIIMTIKGAV . ::.: ... . :: CCDS12 KKPGIYTRVAS-YAAWIDSVLA 240 250 >>CCDS82261.1 CFD gene_id:1675|Hs108|chr19 (260 aa) initn: 613 init1: 313 opt: 621 Z-score: 767.2 bits: 149.6 E(32554): 2.1e-36 Smith-Waterman score: 621; 41.3% identity (70.4% similar) in 230 aa overlap (28-254:32-255) 10 20 30 40 50 pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGA .:.:: :. :.::::. ..:. .:.:. CCDS82 HSWERLAVLVLLGAAACGEEAWAWAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 LIAKDWVLTAAHC---NLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGD :.:..:::.:::: . . ::.:::::... ::.:... : . :.: .: : . : CCDS82 LVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 LKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITII : ::::.::: .. : : . :: :::.:.::::: ..... :.:..: . .. CCDS82 LLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 DRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKC :: .:: :.:. . .: ..:: : : ::::.::::.::.: ::..::.. : : CCDS82 DRATCNRRTHH--DGAITERLMCAESNR--RDSCKGDSGGPLVCGGVLEGVVTSG-SRVC 190 200 210 220 230 240 250 260 pF1KB6 GDPRGPGVYILLSKKHLNWIIMTIKGAV :. . ::.: ... . :: CCDS82 GNRKKPGIYTRVAS-YAAWIDSVLA 240 250 260 >>CCDS9633.1 GZMB gene_id:3002|Hs108|chr14 (247 aa) initn: 553 init1: 296 opt: 582 Z-score: 719.7 bits: 140.7 E(32554): 9.1e-34 Smith-Waterman score: 582; 42.0% identity (70.8% similar) in 250 aa overlap (14-259:6-245) 10 20 30 40 50 pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSL-DRKTI--CAGA .....::.:. .::::.:. :::::::. : . :.:.. :.: CCDS96 MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGF 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 LIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKL :: :.::::::: .. .: ::::.: ..:::.:.. ::. .:.: :.: . .:. : CCDS96 LIRDDFVLTAAHC-WGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIML 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITII-DR ::: .::: .. : :.::.. .:::: :.:::::.: .. : ::.::..:. :: CCDS96 LQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 KVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGD : .: :: .. .: . :.:. . . : .::::.::.:. : .:..:.: .: : CCDS96 KCESDLRHY-YDSTIEL---CVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNN--GM 180 190 200 210 220 240 250 260 pF1KB6 PRGPGVYILLSKKHLNWIIMTIKGAV : : . .:. ..:: :.: CCDS96 P--PRACTKVSS-FVHWIKKTMKRY 230 240 >>CCDS9632.1 GZMH gene_id:2999|Hs108|chr14 (246 aa) initn: 512 init1: 242 opt: 567 Z-score: 701.3 bits: 137.3 E(32554): 9.6e-33 Smith-Waterman score: 585; 41.8% identity (69.9% similar) in 249 aa overlap (14-259:6-244) 10 20 30 40 50 pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLS-LDRKTI--CAGA .....:: : :.::::.:. :::::::.... :..:. :.: CCDS96 MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGI 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 LIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKL :. ::.:::::::. .. .: ::::.: ..: :.:.. ::. .:.: :.: . .:. : CCDS96 LVRKDFVLTAAHCQ-GSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIML 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRK ::: .::: . : :.::.. .:::: .:.::::: . : . . ::.:: .:. CCDS96 LQLERKAKWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMS-TLATTLQEVLLTVQKDC 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 VCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDP :. : :.. . . .:.:. . . . .::::.::.:. : .:. :.: :: : : CCDS96 QCERLFHGNYSRA---TEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYG--NKKGTP 180 190 200 210 220 240 250 260 pF1KB6 RGPGVYILLSKKHLNWIIMTIKGAV ::::: .:. : :: :.: CCDS96 --PGVYIKVSH-FLPWIKRTMKRL 230 240 >>CCDS12823.2 KLK14 gene_id:43847|Hs108|chr19 (267 aa) initn: 518 init1: 175 opt: 559 Z-score: 691.0 bits: 135.5 E(32554): 3.6e-32 Smith-Waterman score: 559; 37.5% identity (67.6% similar) in 256 aa overlap (7-259:19-265) 10 20 30 40 pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYM--VLL .: ..:.:.. . .. .:::::. : :.:.. .: CCDS12 MSLRVLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 SLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCY . :. .:.:::.. .::.:::::. :: :: :.. : : :.:.. : .. .: : CCDS12 GPRRRFLCGGALLSGQWVITAAHCG-RPILQVALGKHNLRRWEATQQVLRVVRQVTHPNY 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 DPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNS-ASWSDT . :...:: :::: . :.:.. : ... . ..::: :.:.::: . : . . CCDS12 NSRTHDNDLMLLQLQQPARIGRAVRPIEVTQAC--ASPGTSCRVSGWGTISSPIARYPAS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 LREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGV :. :::.: .::. ...: .::::: .::.:::.::::.::.:.: ..:. CCDS12 LQCVNINISPDEVCQKAYPRTITP----GMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGL 180 190 200 210 220 230 230 240 250 260 pF1KB6 TSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV .:.:.: .:. : :::: : : . .:: :.. CCDS12 VSWGME-RCALPGYPGVYTNLCK-YRSWIEETMRDK 240 250 260 >>CCDS12813.1 KLK8 gene_id:11202|Hs108|chr19 (260 aa) initn: 354 init1: 206 opt: 539 Z-score: 666.7 bits: 131.0 E(32554): 8.2e-31 Smith-Waterman score: 539; 37.9% identity (65.8% similar) in 240 aa overlap (27-260:31-260) 10 20 30 40 50 pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAG .:..::.: :::.:... : .. .:.: CCDS12 MGRPRPRAAKTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 ALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREG--- .:.. .::::::::. : . : :: ::. .. .: . : . .:.:::. . : CCDS12 VLVGGNWVLTAAHCKKPKYT-VRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNH 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 DLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGR-THNSASWSDTLREVNIT :: :::: ..:.... : . : . ..:: : :.::: : .. ::: ... CCDS12 DLMLLQLRDQASLGSKVKPISLADHC--TQPGQKCTVSGWGTVTSPRENFPDTLNCAEVK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 IIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLEN :. .: :.: . : .:::::: .:. :.:.::::.::.:.:...:.::.: . CCDS12 IFPQKKCED----AYPGQITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWG-SD 180 190 200 210 220 230 240 250 260 pF1KB6 KCGDPRGPGVYILLSKKHLNWI--IMTIKGAV :: :::: . . .:.:: :. :: CCDS12 PCGRSDKPGVYTNICR-YLDWIKKIIGSKG 240 250 260 >>CCDS42600.1 KLK8 gene_id:11202|Hs108|chr19 (305 aa) initn: 354 init1: 206 opt: 539 Z-score: 665.6 bits: 131.0 E(32554): 9.4e-31 Smith-Waterman score: 539; 37.9% identity (65.8% similar) in 240 aa overlap (27-260:76-305) 10 20 30 40 50 pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAG .:..::.: :::.:... : .. .:.: CCDS42 PQWPSQPSHCPRGWRSNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGG 50 60 70 80 90 100 60 70 80 90 100 110 pF1KB6 ALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREG--- .:.. .::::::::. : . : :: ::. .. .: . : . .:.:::. . : CCDS42 VLVGGNWVLTAAHCKKPKYT-VRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNH 110 120 130 140 150 160 120 130 140 150 160 170 pF1KB6 DLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGR-THNSASWSDTLREVNIT :: :::: ..:.... : . : . ..:: : :.::: : .. ::: ... CCDS42 DLMLLQLRDQASLGSKVKPISLADHC--TQPGQKCTVSGWGTVTSPRENFPDTLNCAEVK 170 180 190 200 210 220 180 190 200 210 220 230 pF1KB6 IIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLEN :. .: :.: . : .:::::: .:. :.:.::::.::.:.:...:.::.: . CCDS42 IFPQKKCED----AYPGQITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWG-SD 230 240 250 260 270 240 250 260 pF1KB6 KCGDPRGPGVYILLSKKHLNWI--IMTIKGAV :: :::: . . .:.:: :. :: CCDS42 PCGRSDKPGVYTNICR-YLDWIKKIIGSKG 280 290 300 >>CCDS9630.1 CMA1 gene_id:1215|Hs108|chr14 (247 aa) initn: 524 init1: 292 opt: 528 Z-score: 653.5 bits: 128.5 E(32554): 4.4e-30 Smith-Waterman score: 542; 40.7% identity (67.1% similar) in 231 aa overlap (28-254:21-240) 10 20 30 40 50 pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKT----ICAG .::::.: :::::::. : . .. .:.: CCDS96 MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGG 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 ALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLK :: ...::::::: .. : ::::.::.:: : : . : :.: .: :. .: . :. CCDS96 FLIRRNFVLTAAHCA-GRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDR ::.: :::... : : .:.. . : :: ::.::::::: ::::.::.. ..: CCDS96 LLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 KVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGD ..:. .. : ..:.:. : ... .::::.:::: :: .:..:.: .: CCDS96 QACSHFRDFDHNL-----QLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGR----SD 180 190 200 210 220 240 250 260 pF1KB6 PRGPGVYILLSKKHLNWIIMTIKGAV . :.:. .:. . :: CCDS96 AKPPAVFTRISH-YRPWINQILQAN 230 240 262 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:57:11 2016 done: Sat Nov 5 07:57:11 2016 Total Scan time: 2.280 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]