FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6340, 290 aa
  1>>>pF1KB6340 290 - 290 aa - 290 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7010+/-0.000296; mu= 14.2154+/- 0.019
 mean_var=83.6248+/-17.071, 0's: 0 Z-trim(118.8): 6  B-trim: 302 in 2/51
 Lambda= 0.140251
 statistics sampled from 32064 (32070) to 32064 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.376), width:  16
 Scan time:  7.960

The best scores are:                                      opt bits E(85289)
NP_060386 (OMIM: 611480) PIH1 domain-containing pr ( 290) 1923 398.3 9.1e-111
XP_006723317 (OMIM: 611480) PREDICTED: PIH1 domain ( 163) 1068 225.1 6.9e-59


>>NP_060386 (OMIM: 611480) PIH1 domain-containing protei  (290 aa)
 initn: 1923 init1: 1923 opt: 1923  Z-score: 2109.6  bits: 398.3 E(85289): 9.1e-111
Smith-Waterman score: 1923; 99.0% identity (99.7% similar) in 290 aa overlap (1-290:1-290)

               10        20        30        40        50        60
pF1KB6 MANPKLLGLELSEAEAIGADSARFEELLLQASKELQQAQTTRPESTQIQPQPGFCIKTNS
       ::::::::. ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MANPKLLGMGLSEAEAIGADSARFEELLLQASKELQQAQTTRPESTQIQPQPGFCIKTNS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 SEGKVFINICHSPSIPPPADVTEEELLQMLEEDQAGFRIPMSLGEPHAELDAKGQGCTAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SEGKVFINICHSPSIPPPADVTEEELLQMLEEDQAGFRIPMSLGEPHAELDAKGQGCTAY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DVAVNSDFYRRMQNSDFLRELVITIAREGLEDKYNLQLNPEWRMMKNRPFMGSISQQNIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DVAVNSDFYRRMQNSDFLRELVITIAREGLEDKYNLQLNPEWRMMKNRPFMGSISQQNIR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 SEQRPRIQELGDLYTPAPGRAESGPEKPHLNLWLEAPDLLLAEIDLPKLDGALGLSLEIG
       :::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_060 SEQRPRIQELGDLYTPAPGRAESGPEKPHLNLWLEAPDLLLAEVDLPKLDGALGLSLEIG
              190       200       210       220       230       240

              250       260       270       280       290
pF1KB6 ENRLVMGGPQQLYHLDAYIPLQINSHESKAAFHRKRKQLMVAMPLLPVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ENRLVMGGPQQLYHLDAYIPLQINSHESKAAFHRKRKQLMVAMPLLPVPS
              250       260       270       280       290

>>XP_006723317 (OMIM: 611480) PREDICTED: PIH1 domain-con  (163 aa)
 initn: 1068 init1: 1068 opt: 1068  Z-score: 1178.2  bits: 225.1 E(85289): 6.9e-59
Smith-Waterman score: 1068; 99.4% identity (100.0% similar) in 159 aa overlap (132-290:5-163)

             110       120       130       140       150       160 
pF1KB6 SLGEPHAELDAKGQGCTAYDVAVNSDFYRRMQNSDFLRELVITIAREGLEDKYNLQLNPE
                                     ::::::::::::::::::::::::::::::
XP_006                           MQNWMQNSDFLRELVITIAREGLEDKYNLQLNPE
                                         10        20        30    

             170       180       190       200       210       220 
pF1KB6 WRMMKNRPFMGSISQQNIRSEQRPRIQELGDLYTPAPGRAESGPEKPHLNLWLEAPDLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WRMMKNRPFMGSISQQNIRSEQRPRIQELGDLYTPAPGRAESGPEKPHLNLWLEAPDLLL
           40        50        60        70        80        90    

             230       240       250       260       270       280 
pF1KB6 AEIDLPKLDGALGLSLEIGENRLVMGGPQQLYHLDAYIPLQINSHESKAAFHRKRKQLMV
       ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEVDLPKLDGALGLSLEIGENRLVMGGPQQLYHLDAYIPLQINSHESKAAFHRKRKQLMV
          100       110       120       130       140       150    

             290
pF1KB6 AMPLLPVPS
       :::::::::
XP_006 AMPLLPVPS
          160   




290 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:32:25 2016 done: Fri Nov  4 20:32:26 2016
 Total Scan time:  7.960 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]