FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6344, 291 aa 1>>>pF1KB6344 291 - 291 aa - 291 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3456+/-0.000831; mu= 15.6823+/- 0.050 mean_var=80.5990+/-15.557, 0's: 0 Z-trim(108.5): 51 B-trim: 100 in 1/48 Lambda= 0.142860 statistics sampled from 10205 (10259) to 10205 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.315), width: 16 Scan time: 2.540 The best scores are: opt bits E(32554) CCDS31224.1 DUSP13 gene_id:51207|Hs108|chr10 ( 248) 1311 279.5 1.7e-75 CCDS7346.1 DUSP13 gene_id:51207|Hs108|chr10 ( 198) 1294 276.0 1.6e-74 CCDS31223.1 DUPD1 gene_id:338599|Hs108|chr10 ( 220) 609 134.8 5.5e-32 CCDS6092.1 DUSP26 gene_id:78986|Hs108|chr8 ( 211) 590 130.9 8e-31 CCDS53542.1 DUSP13 gene_id:51207|Hs108|chr10 ( 188) 513 115.0 4.4e-26 CCDS30932.1 DUSP27 gene_id:92235|Hs108|chr1 (1158) 502 113.3 8.5e-25 CCDS11469.1 DUSP3 gene_id:1845|Hs108|chr17 ( 185) 433 98.5 4e-21 CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 ( 303) 269 64.8 8.7e-11 CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 ( 198) 266 64.1 9.6e-11 >>CCDS31224.1 DUSP13 gene_id:51207|Hs108|chr10 (248 aa) initn: 1312 init1: 1294 opt: 1311 Z-score: 1469.0 bits: 279.5 E(32554): 1.7e-75 Smith-Waterman score: 1311; 91.4% identity (94.6% similar) in 222 aa overlap (72-291:28-248) 50 60 70 80 90 pF1KB6 SIWLLLAPTPPLSHCLQSPQKQHQVCGDRRLKAGSTNCPSEKCTAWARY--SHRMDSLQK :.::...: :. .: . :::::: CCDS31 MAETSLPELGGEDKATPCPSILELEELLRAGKSSC-SRVDEVWPNLFIGDAMDSLQK 10 20 30 40 50 100 110 120 130 140 150 pF1KB6 QDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 QDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSK 60 70 80 90 100 110 160 170 180 190 200 210 pF1KB6 LIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAA 120 130 140 150 160 170 220 230 240 250 260 270 pF1KB6 LSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQLQV ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: CCDS31 LSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQV 180 190 200 210 220 230 280 290 pF1KB6 LDNRLGRETGRF :::::::::::: CCDS31 LDNRLGRETGRF 240 >>CCDS7346.1 DUSP13 gene_id:51207|Hs108|chr10 (198 aa) initn: 1294 init1: 1294 opt: 1294 Z-score: 1451.4 bits: 276.0 E(32554): 1.6e-74 Smith-Waterman score: 1294; 99.5% identity (99.5% similar) in 198 aa overlap (94-291:1-198) 70 80 90 100 110 120 pF1KB6 HQVCGDRRLKAGSTNCPSEKCTAWARYSHRMDSLQKQDLRRPKIHGAVQASPYQPPTLAS :::::::::::::::::::::::::::::: CCDS73 MDSLQKQDLRRPKIHGAVQASPYQPPTLAS 10 20 30 130 140 150 160 170 180 pF1KB6 LQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 LQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAK 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB6 FYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 FYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVL 100 110 120 130 140 150 250 260 270 280 290 pF1KB6 AFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF ::::: :::::::::::::::::::::::::::::::::::::::::: CCDS73 AFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF 160 170 180 190 >>CCDS31223.1 DUPD1 gene_id:338599|Hs108|chr10 (220 aa) initn: 596 init1: 554 opt: 609 Z-score: 687.8 bits: 134.8 E(32554): 5.5e-32 Smith-Waterman score: 609; 48.9% identity (75.3% similar) in 186 aa overlap (105-290:22-206) 80 90 100 110 120 130 pF1KB6 GSTNCPSEKCTAWARYSHRMDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAA ::.. . : : :.::.: . . CCDS31 MTSGEVKTSLKNAYSSAKRLSPKMEEEGEEEDYCTPGAFELERLFW-KGSP 10 20 30 40 50 140 150 160 170 180 190 pF1KB6 TLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYG .:..::::.:..:: .: :. .: . :.:::.::: :...:::: .:: :...:.: CCDS31 QYTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHG 60 70 80 90 100 110 200 210 220 230 240 250 pF1KB6 IEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTL .:::: : :::::.: :.: .: ::: ....::::.:: :::::::::.:::...::: CCDS31 VEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTL 120 130 140 150 160 170 260 270 280 290 pF1KB6 VEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF :.::: : .: . :: :::.::. ::..: .. : CCDS31 VDAIQQVAKNRCVLPNRGFLKQLRELDKQLVQQRRRSQRQDGEEEDGREL 180 190 200 210 220 >>CCDS6092.1 DUSP26 gene_id:78986|Hs108|chr8 (211 aa) initn: 564 init1: 410 opt: 590 Z-score: 666.9 bits: 130.9 E(32554): 8e-31 Smith-Waterman score: 590; 47.1% identity (73.8% similar) in 210 aa overlap (79-284:2-205) 50 60 70 80 90 100 pF1KB6 PTPPLSHCLQSPQKQHQVCGDRRLKAGSTNCPSEKCTAWARYSHRMDSLQKQDLRRP-KI ::.. :: .. : ..... : : . CCDS60 MCPGNWL--WASMTF-MARFSRSSSRSPVRT 10 20 110 120 130 140 150 160 pF1KB6 HGAVQASP-YQPPTLA--SLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG .:... : : : : :.:::.. ..: :: :::::.:.::: : .. .: .:: CCDS60 RGTLEEMPTVQHPFLNVFELERLLYTGKTAC-NHADEVWPGLYLGDQDMANNRRELRRLG 30 40 50 60 70 80 170 180 190 200 210 220 pF1KB6 ITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQ ::::.::. .... : :.:....: :.:: :.: ::.:..: .: .:. ::: : CCDS60 ITHVLNASHSRWRGTPEA--YEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPG 90 100 110 120 130 140 230 240 250 260 270 280 pF1KB6 GRVLVHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL :..:::::.:::::::::::.::.:...::::::. :. ::.: :: :::::: .:: :: CCDS60 GKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRL 150 160 170 180 190 200 290 pF1KB6 GRETGRF CCDS60 RQGLEA 210 >>CCDS53542.1 DUSP13 gene_id:51207|Hs108|chr10 (188 aa) initn: 481 init1: 289 opt: 513 Z-score: 581.8 bits: 115.0 E(32554): 4.4e-26 Smith-Waterman score: 513; 45.7% identity (74.2% similar) in 186 aa overlap (105-290:7-187) 80 90 100 110 120 130 pF1KB6 GSTNCPSEKCTAWARYSHRMDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAA :.. : .:.: :.. :..:: . ... CCDS53 MAETSLPELGGEDKATPC--PSILELEELLRAGKSS 10 20 30 140 150 160 170 180 190 pF1KB6 TLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYG ...:::::.::.::: .: .. .: .::::::.::: . . : :: : :. : : CCDS53 C-SRVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFY-GSSVSYLG 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 IEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTL . : : : ::.:.:: .: .:. ::..: ..:::::..:::::::::::.::... ..: CCDS53 VPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSL 100 110 120 130 140 150 260 270 280 290 pF1KB6 VEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF .:. ::. :: . :: :::.:: ::..: : .:. CCDS53 RQAVITVRQHRWVFPNRGFLHQLCRLDQQL-RGAGQS 160 170 180 >>CCDS30932.1 DUSP27 gene_id:92235|Hs108|chr1 (1158 aa) initn: 481 init1: 337 opt: 502 Z-score: 558.7 bits: 113.3 E(32554): 8.5e-25 Smith-Waterman score: 502; 45.7% identity (76.0% similar) in 175 aa overlap (114-287:108-281) 90 100 110 120 130 140 pF1KB6 CTAWARYSHRMDSLQKQDLRRPKIHGAVQASPYQPPTLASLQR-LLWVRQAATLNHIDEV : :. : . .::: :. :: : :..::: CCDS30 DAECPGMLESAEQLLVEDLYNRVREKMDDTSLYNTPCVLDLQRALVQDRQEAPWNEVDEV 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB6 WPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPF ::..:... .: .:..: .:::::..::: : : :: .:: :. ..: :.:.:: : CCDS30 WPNVFIAEKSVAVNKGRLKRLGITHILNAAHGT-GVYTGPEFYTGLEIQYLGVEVDDFPE 140 150 160 170 180 190 210 220 230 240 250 260 pF1KB6 FDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQ :.: .: ..... :: . .:.::: ::.::::.::.:.:::..::...::..::. CCDS30 VDISQHFRKASEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVR 200 210 220 230 240 250 270 280 290 pF1KB6 AHRNICPNSGFLRQLQVLDNRLGRETGRF .: : :: :::.::. :...: .: CCDS30 KKRAIYPNEGFLKQLRELNEKLMEEREEDYGREGGSAEAEEGEGTGSMLGARVHALTVEE 260 270 280 290 300 310 >>CCDS11469.1 DUSP3 gene_id:1845|Hs108|chr17 (185 aa) initn: 433 init1: 304 opt: 433 Z-score: 492.8 bits: 98.5 E(32554): 4e-21 Smith-Waterman score: 433; 47.3% identity (76.0% similar) in 150 aa overlap (140-287:31-180) 110 120 130 140 150 160 pF1KB6 AVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVV .:: : ...:.: .:.: :: .::::::. CCDS11 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL 10 20 30 40 50 60 170 180 190 200 210 220 pF1KB6 NAAAGK--FQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRV ::: :. ..:.:.:.::. .. : ::.:.:. :.::.:: .: .: ::. .::: CCDS11 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV 70 80 90 100 110 120 230 240 250 260 270 280 pF1KB6 LVHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE :::: : ::: :::.:.::. ..: . :.. :. .:.: ::.::: :: :..::..: CCDS11 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE 130 140 150 160 170 180 290 pF1KB6 TGRF CCDS11 GKLKP >>CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 (303 aa) initn: 217 init1: 149 opt: 269 Z-score: 307.1 bits: 64.8 E(32554): 8.7e-11 Smith-Waterman score: 271; 32.7% identity (59.4% similar) in 217 aa overlap (74-284:42-243) 50 60 70 80 90 100 pF1KB6 WLLLAPTPPLSHCLQSPQKQHQVCGDRRLKAGSTNCP-SEKCTAWARYSHRMDSLQKQDL :: . : ::. .. :.: .. . . CCDS60 FAEHSRSPRRTGRDCKPVRAPSMALGVSQLAGRSRCLCSESQGGYERFSSEYPEFCS--- 20 30 40 50 60 110 120 130 140 150 pF1KB6 RRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHID----EVWPSLFLGDAYAARDKS . : .:. : ::. :. : . .: : . :. : :.::.:: : .. CCDS60 -KTKALAAIP--PPVPPS-ATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRD 70 80 90 100 110 120 160 170 180 190 200 210 pF1KB6 KLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRA : :::: ..:... : .: .: .: : ..:: :.: .:. . .:: : CCDS60 MLDALGITALLNVSS-----DCPNHF-EGH-YQYKCIPVEDNHKADISSWFMEAIEYIDA 130 140 150 160 170 220 230 240 250 260 270 pF1KB6 ALSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQAHRNI-CPNSGFLRQL . . .::::::: :.:::::. ::.::. . . : ::.. :. .:.: :: .:. :: CCDS60 VKDC-RGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQL 180 190 200 210 220 230 280 290 pF1KB6 QVLDNRLGRETGRF ..... CCDS60 LQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSP 240 250 260 270 280 290 >>CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 (198 aa) initn: 203 init1: 146 opt: 266 Z-score: 306.3 bits: 64.1 E(32554): 9.6e-11 Smith-Waterman score: 266; 38.2% identity (62.5% similar) in 152 aa overlap (139-288:27-170) 110 120 130 140 150 160 pF1KB6 GAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHV : .. ::::: . .: .. : ::: . CCDS11 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCI 10 20 30 40 50 170 180 190 200 210 220 pF1KB6 VNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVL :::. ... . . ..:: . : : ...:: :: :.. .: .: .: CCDS11 VNAT---IEIPN----FNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHS-VSRKHGATL 60 70 80 90 100 230 240 250 260 270 280 pF1KB6 VHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQAHRNIC-PNSGFLRQLQVLDNRL-GR :::: :::::::: .:.:: ..:. :.:: . :.:.: . :: :: ::: . .: :. CCDS11 VHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGK 110 120 130 140 150 160 290 pF1KB6 ETGRF : CCDS11 STVKMVQTPYGIVPDVYEKESRHLMPYWGI 170 180 190 291 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:32:53 2016 done: Fri Nov 4 20:32:54 2016 Total Scan time: 2.540 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]