FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6344, 291 aa
1>>>pF1KB6344 291 - 291 aa - 291 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3456+/-0.000831; mu= 15.6823+/- 0.050
mean_var=80.5990+/-15.557, 0's: 0 Z-trim(108.5): 51 B-trim: 100 in 1/48
Lambda= 0.142860
statistics sampled from 10205 (10259) to 10205 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.315), width: 16
Scan time: 2.540
The best scores are: opt bits E(32554)
CCDS31224.1 DUSP13 gene_id:51207|Hs108|chr10 ( 248) 1311 279.5 1.7e-75
CCDS7346.1 DUSP13 gene_id:51207|Hs108|chr10 ( 198) 1294 276.0 1.6e-74
CCDS31223.1 DUPD1 gene_id:338599|Hs108|chr10 ( 220) 609 134.8 5.5e-32
CCDS6092.1 DUSP26 gene_id:78986|Hs108|chr8 ( 211) 590 130.9 8e-31
CCDS53542.1 DUSP13 gene_id:51207|Hs108|chr10 ( 188) 513 115.0 4.4e-26
CCDS30932.1 DUSP27 gene_id:92235|Hs108|chr1 (1158) 502 113.3 8.5e-25
CCDS11469.1 DUSP3 gene_id:1845|Hs108|chr17 ( 185) 433 98.5 4e-21
CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 ( 303) 269 64.8 8.7e-11
CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 ( 198) 266 64.1 9.6e-11
>>CCDS31224.1 DUSP13 gene_id:51207|Hs108|chr10 (248 aa)
initn: 1312 init1: 1294 opt: 1311 Z-score: 1469.0 bits: 279.5 E(32554): 1.7e-75
Smith-Waterman score: 1311; 91.4% identity (94.6% similar) in 222 aa overlap (72-291:28-248)
50 60 70 80 90
pF1KB6 SIWLLLAPTPPLSHCLQSPQKQHQVCGDRRLKAGSTNCPSEKCTAWARY--SHRMDSLQK
:.::...: :. .: . ::::::
CCDS31 MAETSLPELGGEDKATPCPSILELEELLRAGKSSC-SRVDEVWPNLFIGDAMDSLQK
10 20 30 40 50
100 110 120 130 140 150
pF1KB6 QDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 QDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSK
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB6 LIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAA
120 130 140 150 160 170
220 230 240 250 260 270
pF1KB6 LSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQLQV
::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
CCDS31 LSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQV
180 190 200 210 220 230
280 290
pF1KB6 LDNRLGRETGRF
::::::::::::
CCDS31 LDNRLGRETGRF
240
>>CCDS7346.1 DUSP13 gene_id:51207|Hs108|chr10 (198 aa)
initn: 1294 init1: 1294 opt: 1294 Z-score: 1451.4 bits: 276.0 E(32554): 1.6e-74
Smith-Waterman score: 1294; 99.5% identity (99.5% similar) in 198 aa overlap (94-291:1-198)
70 80 90 100 110 120
pF1KB6 HQVCGDRRLKAGSTNCPSEKCTAWARYSHRMDSLQKQDLRRPKIHGAVQASPYQPPTLAS
::::::::::::::::::::::::::::::
CCDS73 MDSLQKQDLRRPKIHGAVQASPYQPPTLAS
10 20 30
130 140 150 160 170 180
pF1KB6 LQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAK
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB6 FYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 FYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVL
100 110 120 130 140 150
250 260 270 280 290
pF1KB6 AFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF
::::: ::::::::::::::::::::::::::::::::::::::::::
CCDS73 AFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF
160 170 180 190
>>CCDS31223.1 DUPD1 gene_id:338599|Hs108|chr10 (220 aa)
initn: 596 init1: 554 opt: 609 Z-score: 687.8 bits: 134.8 E(32554): 5.5e-32
Smith-Waterman score: 609; 48.9% identity (75.3% similar) in 186 aa overlap (105-290:22-206)
80 90 100 110 120 130
pF1KB6 GSTNCPSEKCTAWARYSHRMDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAA
::.. . : : :.::.: . .
CCDS31 MTSGEVKTSLKNAYSSAKRLSPKMEEEGEEEDYCTPGAFELERLFW-KGSP
10 20 30 40 50
140 150 160 170 180 190
pF1KB6 TLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYG
.:..::::.:..:: .: :. .: . :.:::.::: :...:::: .:: :...:.:
CCDS31 QYTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHG
60 70 80 90 100 110
200 210 220 230 240 250
pF1KB6 IEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTL
.:::: : :::::.: :.: .: ::: ....::::.:: :::::::::.:::...:::
CCDS31 VEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTL
120 130 140 150 160 170
260 270 280 290
pF1KB6 VEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF
:.::: : .: . :: :::.::. ::..: .. :
CCDS31 VDAIQQVAKNRCVLPNRGFLKQLRELDKQLVQQRRRSQRQDGEEEDGREL
180 190 200 210 220
>>CCDS6092.1 DUSP26 gene_id:78986|Hs108|chr8 (211 aa)
initn: 564 init1: 410 opt: 590 Z-score: 666.9 bits: 130.9 E(32554): 8e-31
Smith-Waterman score: 590; 47.1% identity (73.8% similar) in 210 aa overlap (79-284:2-205)
50 60 70 80 90 100
pF1KB6 PTPPLSHCLQSPQKQHQVCGDRRLKAGSTNCPSEKCTAWARYSHRMDSLQKQDLRRP-KI
::.. :: .. : ..... : : .
CCDS60 MCPGNWL--WASMTF-MARFSRSSSRSPVRT
10 20
110 120 130 140 150 160
pF1KB6 HGAVQASP-YQPPTLA--SLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG
.:... : : : : :.:::.. ..: :: :::::.:.::: : .. .: .::
CCDS60 RGTLEEMPTVQHPFLNVFELERLLYTGKTAC-NHADEVWPGLYLGDQDMANNRRELRRLG
30 40 50 60 70 80
170 180 190 200 210 220
pF1KB6 ITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQ
::::.::. .... : :.:....: :.:: :.: ::.:..: .: .:. ::: :
CCDS60 ITHVLNASHSRWRGTPEA--YEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPG
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB6 GRVLVHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL
:..:::::.:::::::::::.::.:...::::::. :. ::.: :: :::::: .:: ::
CCDS60 GKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRL
150 160 170 180 190 200
290
pF1KB6 GRETGRF
CCDS60 RQGLEA
210
>>CCDS53542.1 DUSP13 gene_id:51207|Hs108|chr10 (188 aa)
initn: 481 init1: 289 opt: 513 Z-score: 581.8 bits: 115.0 E(32554): 4.4e-26
Smith-Waterman score: 513; 45.7% identity (74.2% similar) in 186 aa overlap (105-290:7-187)
80 90 100 110 120 130
pF1KB6 GSTNCPSEKCTAWARYSHRMDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAA
:.. : .:.: :.. :..:: . ...
CCDS53 MAETSLPELGGEDKATPC--PSILELEELLRAGKSS
10 20 30
140 150 160 170 180 190
pF1KB6 TLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYG
...:::::.::.::: .: .. .: .::::::.::: . . : :: : :. : :
CCDS53 C-SRVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFY-GSSVSYLG
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB6 IEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTL
. : : : ::.:.:: .: .:. ::..: ..:::::..:::::::::::.::... ..:
CCDS53 VPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSL
100 110 120 130 140 150
260 270 280 290
pF1KB6 VEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF
.:. ::. :: . :: :::.:: ::..: : .:.
CCDS53 RQAVITVRQHRWVFPNRGFLHQLCRLDQQL-RGAGQS
160 170 180
>>CCDS30932.1 DUSP27 gene_id:92235|Hs108|chr1 (1158 aa)
initn: 481 init1: 337 opt: 502 Z-score: 558.7 bits: 113.3 E(32554): 8.5e-25
Smith-Waterman score: 502; 45.7% identity (76.0% similar) in 175 aa overlap (114-287:108-281)
90 100 110 120 130 140
pF1KB6 CTAWARYSHRMDSLQKQDLRRPKIHGAVQASPYQPPTLASLQR-LLWVRQAATLNHIDEV
: :. : . .::: :. :: : :..:::
CCDS30 DAECPGMLESAEQLLVEDLYNRVREKMDDTSLYNTPCVLDLQRALVQDRQEAPWNEVDEV
80 90 100 110 120 130
150 160 170 180 190 200
pF1KB6 WPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPF
::..:... .: .:..: .:::::..::: : : :: .:: :. ..: :.:.:: :
CCDS30 WPNVFIAEKSVAVNKGRLKRLGITHILNAAHGT-GVYTGPEFYTGLEIQYLGVEVDDFPE
140 150 160 170 180 190
210 220 230 240 250 260
pF1KB6 FDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQ
:.: .: ..... :: . .:.::: ::.::::.::.:.:::..::...::..::.
CCDS30 VDISQHFRKASEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVR
200 210 220 230 240 250
270 280 290
pF1KB6 AHRNICPNSGFLRQLQVLDNRLGRETGRF
.: : :: :::.::. :...: .:
CCDS30 KKRAIYPNEGFLKQLRELNEKLMEEREEDYGREGGSAEAEEGEGTGSMLGARVHALTVEE
260 270 280 290 300 310
>>CCDS11469.1 DUSP3 gene_id:1845|Hs108|chr17 (185 aa)
initn: 433 init1: 304 opt: 433 Z-score: 492.8 bits: 98.5 E(32554): 4e-21
Smith-Waterman score: 433; 47.3% identity (76.0% similar) in 150 aa overlap (140-287:31-180)
110 120 130 140 150 160
pF1KB6 AVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVV
.:: : ...:.: .:.: :: .::::::.
CCDS11 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
10 20 30 40 50 60
170 180 190 200 210 220
pF1KB6 NAAAGK--FQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRV
::: :. ..:.:.:.::. .. : ::.:.:. :.::.:: .: .: ::. .:::
CCDS11 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
70 80 90 100 110 120
230 240 250 260 270 280
pF1KB6 LVHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE
:::: : ::: :::.:.::. ..: . :.. :. .:.: ::.::: :: :..::..:
CCDS11 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
130 140 150 160 170 180
290
pF1KB6 TGRF
CCDS11 GKLKP
>>CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 (303 aa)
initn: 217 init1: 149 opt: 269 Z-score: 307.1 bits: 64.8 E(32554): 8.7e-11
Smith-Waterman score: 271; 32.7% identity (59.4% similar) in 217 aa overlap (74-284:42-243)
50 60 70 80 90 100
pF1KB6 WLLLAPTPPLSHCLQSPQKQHQVCGDRRLKAGSTNCP-SEKCTAWARYSHRMDSLQKQDL
:: . : ::. .. :.: .. . .
CCDS60 FAEHSRSPRRTGRDCKPVRAPSMALGVSQLAGRSRCLCSESQGGYERFSSEYPEFCS---
20 30 40 50 60
110 120 130 140 150
pF1KB6 RRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHID----EVWPSLFLGDAYAARDKS
. : .:. : ::. :. : . .: : . :. : :.::.:: : ..
CCDS60 -KTKALAAIP--PPVPPS-ATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRD
70 80 90 100 110 120
160 170 180 190 200 210
pF1KB6 KLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRA
: :::: ..:... : .: .: .: : ..:: :.: .:. . .:: :
CCDS60 MLDALGITALLNVSS-----DCPNHF-EGH-YQYKCIPVEDNHKADISSWFMEAIEYIDA
130 140 150 160 170
220 230 240 250 260 270
pF1KB6 ALSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQAHRNI-CPNSGFLRQL
. . .::::::: :.:::::. ::.::. . . : ::.. :. .:.: :: .:. ::
CCDS60 VKDC-RGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQL
180 190 200 210 220 230
280 290
pF1KB6 QVLDNRLGRETGRF
.....
CCDS60 LQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSP
240 250 260 270 280 290
>>CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 (198 aa)
initn: 203 init1: 146 opt: 266 Z-score: 306.3 bits: 64.1 E(32554): 9.6e-11
Smith-Waterman score: 266; 38.2% identity (62.5% similar) in 152 aa overlap (139-288:27-170)
110 120 130 140 150 160
pF1KB6 GAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHV
: .. ::::: . .: .. : ::: .
CCDS11 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCI
10 20 30 40 50
170 180 190 200 210 220
pF1KB6 VNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVL
:::. ... . . ..:: . : : ...:: :: :.. .: .: .:
CCDS11 VNAT---IEIPN----FNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHS-VSRKHGATL
60 70 80 90 100
230 240 250 260 270 280
pF1KB6 VHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQAHRNIC-PNSGFLRQLQVLDNRL-GR
:::: :::::::: .:.:: ..:. :.:: . :.:.: . :: :: ::: . .: :.
CCDS11 VHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGK
110 120 130 140 150 160
290
pF1KB6 ETGRF
:
CCDS11 STVKMVQTPYGIVPDVYEKESRHLMPYWGI
170 180 190
291 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:32:53 2016 done: Fri Nov 4 20:32:54 2016
Total Scan time: 2.540 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]