FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6347, 266 aa 1>>>pF1KB6347 266 - 266 aa - 266 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2396+/-0.000386; mu= 15.5924+/- 0.024 mean_var=86.5053+/-17.884, 0's: 0 Z-trim(113.9): 128 B-trim: 68 in 1/54 Lambda= 0.137896 statistics sampled from 23327 (23478) to 23327 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.275), width: 16 Scan time: 7.180 The best scores are: opt bits E(85289) NP_072049 (OMIM: 612735) major histocompatibility ( 266) 1734 354.8 9.1e-98 NP_001230894 (OMIM: 126200,142857,180300,181000) m ( 266) 1679 343.9 1.8e-94 XP_011546040 (OMIM: 126200,142857,180300,181000) P ( 266) 1640 336.1 3.9e-92 NP_002115 (OMIM: 126200,142857,180300,181000) majo ( 266) 1607 329.6 3.7e-90 NP_002116 (OMIM: 604776) major histocompatibility ( 266) 1541 316.5 3.3e-86 XP_011512864 (OMIM: 604776) PREDICTED: major histo ( 276) 1526 313.5 2.7e-85 NP_001230890 (OMIM: 123400,126200,212750,604305) H ( 269) 1104 229.5 4.9e-60 NP_001287719 (OMIM: 615161) HLA class II histocomp ( 264) 1100 228.7 8.5e-60 XP_005249108 (OMIM: 615161) PREDICTED: HLA class I ( 275) 1097 228.1 1.3e-59 NP_001230891 (OMIM: 123400,126200,212750,604305) H ( 261) 1089 226.5 3.8e-59 NP_002114 (OMIM: 123400,126200,212750,604305) HLA ( 261) 1079 224.5 1.5e-58 XP_011512862 (OMIM: 615161) PREDICTED: HLA class I ( 256) 1076 223.9 2.3e-58 NP_002112 (OMIM: 142858) HLA class II histocompati ( 258) 1041 217.0 2.8e-56 NP_002111 (OMIM: 600629) HLA class II histocompati ( 273) 947 198.3 1.3e-50 NP_001185787 (OMIM: 615161) HLA class II histocomp ( 227) 896 188.1 1.2e-47 XP_011512863 (OMIM: 615161) PREDICTED: HLA class I ( 219) 890 186.9 2.8e-47 XP_011507765 (OMIM: 600764) PREDICTED: major histo ( 254) 289 67.4 3e-11 NP_002109 (OMIM: 142856) HLA class II histocompati ( 263) 286 66.8 4.7e-11 NP_001522 (OMIM: 600764) major histocompatibility ( 341) 283 66.3 8.6e-11 NP_620576 (OMIM: 104300,176100,176200,235200,61263 ( 260) 271 63.8 3.7e-10 NP_620578 (OMIM: 104300,176100,176200,235200,61263 ( 325) 271 63.9 4.4e-10 NP_000401 (OMIM: 104300,176100,176200,235200,61263 ( 348) 271 63.9 4.6e-10 XP_011512845 (OMIM: 104300,176100,176200,235200,61 ( 348) 271 63.9 4.6e-10 NP_001287678 (OMIM: 104300,176100,176200,235200,61 ( 337) 269 63.5 5.9e-10 NP_001176 (OMIM: 194460) zinc-alpha-2-glycoprotein ( 298) 252 60.1 5.6e-09 NP_002110 (OMIM: 142930) HLA class II histocompati ( 250) 242 58.0 2e-08 NP_001229453 (OMIM: 142880) HLA class II histocomp ( 260) 241 57.8 2.3e-08 NP_291032 (OMIM: 142880) HLA class II histocompati ( 260) 241 57.8 2.3e-08 NP_001229454 (OMIM: 142880) HLA class II histocomp ( 260) 241 57.8 2.3e-08 NP_001181928 (OMIM: 600764) major histocompatibili ( 296) 239 57.5 3.4e-08 NP_620573 (OMIM: 104300,176100,176200,235200,61263 ( 256) 234 56.4 6e-08 NP_620577 (OMIM: 104300,176100,176200,235200,61263 ( 246) 231 55.8 8.9e-08 NP_002113 (OMIM: 146880,212750) HLA class II histo ( 255) 231 55.8 9.1e-08 NP_620572 (OMIM: 104300,176100,176200,235200,61263 ( 242) 230 55.6 1e-07 NP_620579 (OMIM: 104300,176100,176200,235200,61263 ( 168) 228 55.1 1e-07 NP_620575 (OMIM: 104300,176100,176200,235200,61263 ( 334) 231 55.9 1.1e-07 NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 230 55.8 1.4e-07 XP_016866307 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 226 54.8 1.8e-07 XP_016866306 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 226 54.8 1.8e-07 NP_005505 (OMIM: 106300,142830,608579) major histo ( 362) 228 55.4 1.8e-07 NP_061984 (OMIM: 142860) HLA class II histocompati ( 254) 224 54.4 2.4e-07 NP_064440 (OMIM: 613503) HLA class II histocompati ( 255) 221 53.8 3.6e-07 NP_001229687 (OMIM: 142800,608579) HLA class I his ( 365) 221 54.0 4.7e-07 XP_006715142 (OMIM: 146880,212750) PREDICTED: HLA ( 206) 218 53.1 4.7e-07 NP_002118 (OMIM: 142871,600807) HLA class I histoc ( 338) 219 53.5 5.8e-07 XP_016866305 (OMIM: 142871,600807) PREDICTED: HLA ( 343) 219 53.6 5.9e-07 XP_016866304 (OMIM: 143110) PREDICTED: HLA class I ( 228) 214 52.4 8.7e-07 XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 215 52.8 1e-06 XP_016866303 (OMIM: 143110) PREDICTED: HLA class I ( 324) 214 52.5 1.1e-06 NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 214 52.6 1.2e-06 >>NP_072049 (OMIM: 612735) major histocompatibility comp (266 aa) initn: 1734 init1: 1734 opt: 1734 Z-score: 1876.2 bits: 354.8 E(85289): 9.1e-98 Smith-Waterman score: 1734; 96.6% identity (98.9% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERYF ::::::::::::::::::::::::::::::::::::::: ::::::::::::::.:.::: NP_072 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVESFTV ::::::.:::::::::::::::::::::::::::::::::::.::::::::::: ::::: NP_072 HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::.:: NP_072 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: NP_072 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFRNQKGHSGLQPTGFLS :::::::::::::::::::::::::: NP_072 FLGAGLFIYFRNQKGHSGLQPTGFLS 250 260 >>NP_001230894 (OMIM: 126200,142857,180300,181000) major (266 aa) initn: 1679 init1: 1679 opt: 1679 Z-score: 1817.1 bits: 343.9 E(85289): 1.8e-94 Smith-Waterman score: 1679; 92.9% identity (96.6% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERYF ::::.::::: .:.:::::::::: ::.:::::::::: :::::::::::::.:.::: NP_001 MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEYSTSECHFFNGTERVRYLDRYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVESFTV ::::: :::::::::.::::::::: :: :::::::::::::.::::::::::::::::: NP_001 HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG ::::::.:::::.::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFRNQKGHSGLQPTGFLS ::::::::::::::::::::: :::: NP_001 FLGAGLFIYFRNQKGHSGLQPRGFLS 250 260 >>XP_011546040 (OMIM: 126200,142857,180300,181000) PREDI (266 aa) initn: 1640 init1: 1640 opt: 1640 Z-score: 1775.1 bits: 336.1 E(85289): 3.9e-92 Smith-Waterman score: 1640; 91.4% identity (96.2% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERYF :::::::::: .:::::::::::: ::.::::.:::: : .::::::::::.:::: : XP_011 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVESFTV .::::::::::::::::::::::::::::::::::.::..:::::. ::::::: ::::: XP_011 YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG ::::::.:::::::::::::::::::::::::::::::::::::::::.::::::::.:: XP_011 QRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_011 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFRNQKGHSGLQPTGFLS :::::::::::::::::::::::::: XP_011 FLGAGLFIYFRNQKGHSGLQPTGFLS 250 260 >>NP_002115 (OMIM: 126200,142857,180300,181000) major hi (266 aa) initn: 1607 init1: 1607 opt: 1607 Z-score: 1739.6 bits: 329.6 E(85289): 3.7e-90 Smith-Waterman score: 1607; 89.5% identity (95.5% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERYF :::::::::: ..::::::::::: ::..:::::::: : ::::::::::::::.::: NP_002 MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECHFFNGTERVRFLDRYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVESFTV .:::: :::::::::.::::::::: :: ::::::.::: :. ::.:::::::::::::: NP_002 YNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAVDTYCRHNYGVVESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG ::::.:.:::::.:::::::::::::::::::::::::::: ::::::.:.::::::.:: NP_002 QRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLNGQEEKAGMVSTGLIQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFRNQKGHSGLQPTGFLS :::::::::::::::::::::::::: NP_002 FLGAGLFIYFRNQKGHSGLQPTGFLS 250 260 >>NP_002116 (OMIM: 604776) major histocompatibility comp (266 aa) initn: 1562 init1: 1541 opt: 1541 Z-score: 1668.7 bits: 316.5 E(85289): 3.3e-86 Smith-Waterman score: 1541; 86.1% identity (95.1% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERYF :::::::::: .: :::::::::: ::.:::::::::. : ::::::::::::::.: . NP_002 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVESFTV .:::: .:::::::::::::::::: :: ::::::.::..:. ::.:::::::: ::::: NP_002 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG ::::.:.::::::.:: :::::::::::.::::::::::::::.::::.::::::::.:: NP_002 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_002 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFRNQKGHSGLQPTGFLS ::::::::::.::::::::.:::..: NP_002 FLGAGLFIYFKNQKGHSGLHPTGLVS 250 260 >>XP_011512864 (OMIM: 604776) PREDICTED: major histocomp (276 aa) initn: 1526 init1: 1526 opt: 1526 Z-score: 1652.3 bits: 313.5 E(85289): 2.7e-85 Smith-Waterman score: 1526; 86.6% identity (95.0% similar) in 262 aa overlap (1-262:1-262) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERYF :::::::::: .: :::::::::: ::.:::::::::. : ::::::::::::::.: . XP_011 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVESFTV .:::: .:::::::::::::::::: :: ::::::.::..:. ::.:::::::: ::::: XP_011 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG ::::.:.::::::.:: :::::::::::.::::::::::::::.::::.::::::::.:: XP_011 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: XP_011 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFRNQKGHSGLQPTGFLS ::::::::::.::::::::.:: XP_011 FLGAGLFIYFKNQKGHSGLHPTVLSSESLKERKRSC 250 260 270 >>NP_001230890 (OMIM: 123400,126200,212750,604305) HLA c (269 aa) initn: 1095 init1: 1075 opt: 1104 Z-score: 1198.8 bits: 229.5 E(85289): 4.9e-60 Smith-Waterman score: 1104; 62.6% identity (82.4% similar) in 262 aa overlap (4-265:7-268) 10 20 30 40 50 pF1KB6 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLE :..:: .:..:. : .::: :: . :. :. .:. :.: :::::::.. NP_001 MSWKKALRIPGDLRVATVTLMLAMLSSLLAEGRDSPEDFVFQFKGMCYFTNGTERVRLVT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 RYFHNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVES ::..:.::..::::::: ::::: ::: :: :::::..:: :...:. ::::: :. NP_001 RYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 FTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLI .::::.: ::. :..:. :.:::::::::. ::::.:.:::::: ::: .::::: :: NP_001 GILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 HNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVL .::::::: ::::: .:. :.::::.:::::. ::.::::::.::::::::::::::::: NP_001 RNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGVGGFVL 190 200 210 220 230 240 240 250 260 pF1KB6 GLLFLGAGLFIYFRNQKGHSGLQPTGFLS ::.::: ::.: :.::: .: :.:.: NP_001 GLIFLGLGLIIRQRSQKGPQGPPPAGLLH 250 260 >>NP_001287719 (OMIM: 615161) HLA class II histocompatib (264 aa) initn: 1065 init1: 804 opt: 1100 Z-score: 1194.6 bits: 228.7 E(85289): 8.5e-60 Smith-Waterman score: 1100; 62.6% identity (82.8% similar) in 262 aa overlap (4-265:3-263) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERYF :..::: ::.:: :..::. .: : : :: .:. :.: ::::::: . ::. NP_001 MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYI 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVESFTV .:.::. ::::::::..::::::: . :.::. ::.:::.:. ::. ::::: . :. NP_001 YNREEYGRFDSDVGEFQAVTELGRSI-EDWNNYKDFLEQERAAVDKVCRHNYEAELRTTL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG ::.:.: ::. :..:. :.:::::::::. :::..:.:::::: ::: .:::::.::.:: NP_001 QRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL ::::: ::::: .:. :..:::::::::. ::.::::::.:::::::::::.:::::::. NP_001 DWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLI 180 190 200 210 220 230 250 260 pF1KB6 FLGAGLFIYFRNQKGHSGLQPTGFLS ::: ::.: :.::: : :.:.: NP_001 FLGLGLIIRHRGQKGPRGPPPAGLLH 240 250 260 >>XP_005249108 (OMIM: 615161) PREDICTED: HLA class II hi (275 aa) initn: 1065 init1: 804 opt: 1097 Z-score: 1191.1 bits: 228.1 E(85289): 1.3e-59 Smith-Waterman score: 1097; 62.4% identity (82.5% similar) in 263 aa overlap (4-266:3-264) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERYF :..::: ::.:: :..::. .: : : :: .:. :.: ::::::: . ::. XP_005 MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYI 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVESFTV .:.::. ::::::::..::::::: . :.::. ::.:::.:. ::. ::::: . :. XP_005 YNREEYGRFDSDVGEFQAVTELGRSI-EDWNNYKDFLEQERAAVDKVCRHNYEAELRTTL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG ::.:.: ::. :..:. :.:::::::::. :::..:.:::::: ::: .:::::.::.:: XP_005 QRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL ::::: ::::: .:. :..:::::::::. ::.::::::.:::::::::::.:::::::. XP_005 DWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLI 180 190 200 210 220 230 250 260 pF1KB6 FLGAGLFIYFRNQKGHSGLQPTGFLS ::: ::.: :.::: : :.: .: XP_005 FLGLGLIIRHRGQKGPRGPPPAGNISAMIQSGERAQA 240 250 260 270 >>NP_001230891 (OMIM: 123400,126200,212750,604305) HLA c (261 aa) initn: 1089 init1: 1089 opt: 1089 Z-score: 1182.8 bits: 226.5 E(85289): 3.8e-59 Smith-Waterman score: 1089; 63.5% identity (83.7% similar) in 252 aa overlap (4-255:7-258) 10 20 30 40 50 pF1KB6 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLE :..::: :..:. : .::. .: . :. :. .:. :.: :::::::.. NP_001 MSWKKALRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 RYFHNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVES : ..:.::.:::::::::.:::: :: :.:: ::::::.::.::. :: ::::: . NP_001 RSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 FTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLI :.::::.: ::. :..:. :.:::::::::. :::..:.:::::: ::: .::::: :: NP_001 TTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 HNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVL .::::::: ::::: .:. :.::::.:::::. ::.::::::.:::::::::::.::::: NP_001 RNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVL 190 200 210 220 230 240 240 250 260 pF1KB6 GLLFLGAGLFIYFRNQKGHSGLQPTGFLS ::.::: ::.:. :.::: NP_001 GLIFLGLGLIIHHRSQKGLLH 250 260 266 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:52:20 2016 done: Fri Nov 4 18:52:21 2016 Total Scan time: 7.180 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]