FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6351, 266 aa
  1>>>pF1KB6351 266 - 266 aa - 266 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3221+/-0.000751; mu= 12.0752+/- 0.045
 mean_var=119.1300+/-23.940, 0's: 0 Z-trim(113.1): 8  B-trim: 0 in 0/52
 Lambda= 0.117507
 statistics sampled from 13755 (13761) to 13755 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.423), width:  16
 Scan time:  2.590

The best scores are:                                      opt bits E(32554)
CCDS7246.1 DKK1 gene_id:22943|Hs108|chr10          ( 266) 1896 331.6 3.5e-91
CCDS3675.1 DKK2 gene_id:27123|Hs108|chr4           ( 259)  728 133.6 1.4e-31
CCDS6130.1 DKK4 gene_id:27121|Hs108|chr8           ( 224)  531 100.1 1.4e-21


>>CCDS7246.1 DKK1 gene_id:22943|Hs108|chr10               (266 aa)
 initn: 1896 init1: 1896 opt: 1896  Z-score: 1750.4  bits: 331.6 E(32554): 3.5e-91
Smith-Waterman score: 1896; 100.0% identity (100.0% similar) in 266 aa overlap (1-266:1-266)

               10        20        30        40        50        60
pF1KB6 MMALGAAGATRVFVAMVAAALGGHPLLGVSATLNSVLNSNAIKNLPPPLGGAAGHPGSAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 MMALGAAGATRVFVAMVAAALGGHPLLGVSATLNSVLNSNAIKNLPPPLGGAAGHPGSAV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 SAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 SAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 CMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 CMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 TKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 TKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCG
              190       200       210       220       230       240

              250       260      
pF1KB6 EGLSCRIQKDHHQASNSSRLHTCQRH
       ::::::::::::::::::::::::::
CCDS72 EGLSCRIQKDHHQASNSSRLHTCQRH
              250       260      

>>CCDS3675.1 DKK2 gene_id:27123|Hs108|chr4                (259 aa)
 initn: 595 init1: 436 opt: 728  Z-score: 680.5  bits: 133.6 E(32554): 1.4e-31
Smith-Waterman score: 728; 42.5% identity (68.1% similar) in 273 aa overlap (1-265:1-258)

               10        20        30        40        50        60
pF1KB6 MMALGAAGATRVFVAMVAAALGGHPLLGVSATLNSVLNSNAIKNLPPPLGGAAGHPGSAV
       : ::  .  .   . ..::.:    ..  :   .:  . :.::.    ::: .  ::.:.
CCDS36 MAALMRSKDSSCCLLLLAAVL----MVESSQIGSSRAKLNSIKS---SLGGET--PGQAA
               10        20            30        40             50 

               70           80        90       100       110       
pF1KB6 SAAPGILYPG---GNKYQTIDNYQPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKR
       . . : .: :   :.. .  .  : :::. :.:: . .:: :: .:..:    :..::..
CCDS36 NRSAG-MYQGLAFGGSKKGKNLGQAYPCSSDKECEVGRYCHSPHQGSSA----CMVCRRK
               60        70        80        90           100      

       120       130       140       150          160         170  
pF1KB6 RKRCMRHAMCCPGNYCKNGICVSSDQNHFRGEI---EETITESFGNDH-STLD-GYSRRT
       .::: : .::::.. :.::::.   .. .  .:   . :  .. .. : :. : :..   
CCDS36 KKRCHRDGMCCPSTRCNNGICIPVTESILTPHIPALDGTRHRDRNHGHYSNHDLGWQNLG
        110       120       130       140       150       160      

            180       190       200       210       220       230  
pF1KB6 TLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLE
          .:: : ::.::. :::::::  :.:::::::.:::::::..:.::::.:.:::::::
CCDS36 RPHTKMSHIKGHEGDPCLRSSDCIEGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLE
        170       180       190       200       210       220      

            240       250       260      
pF1KB6 IFQRCYCGEGLSCRIQKDHHQASNSSRLHTCQRH
       ::::: :..::::.. ::   .:.. :::.::. 
CCDS36 IFQRCDCAKGLSCKVWKDATYSSKA-RLHVCQKI
        230       240       250          

>>CCDS6130.1 DKK4 gene_id:27121|Hs108|chr8                (224 aa)
 initn: 500 init1: 257 opt: 531  Z-score: 500.8  bits: 100.1 E(32554): 1.4e-21
Smith-Waterman score: 531; 42.5% identity (64.5% similar) in 186 aa overlap (85-265:41-220)

           60        70        80        90       100       110    
pF1KB6 HPGSAVSAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTRGGDAGVQICLAC
                                     :  : .:.: ..: .:    :    .: .:
CCDS61 WLCSPLGALVLDFNNIRSSADLHGARKGSQCLSDTDCNTRKFCLQPR---DEK-PFCATC
               20        30        40        50           60       

          120       130       140          150       160        170
pF1KB6 RKRRKRCMRHAMCCPGNYCKNGICVSSDQNH---FRGEIEETITESFGND-HSTLDGYSR
       :  :.::.: ::::::. : : .:.. ..      :   :.  :.. :.  : . ..  .
CCDS61 RGLRRRCQRDAMCCPGTLCVNDVCTTMEDATPILERQLDEQDGTHAEGTTGHPVQENQPK
         70        80        90       100       110       120      

              180       190       200       210       220          
pF1KB6 RTTLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGS-H
       :    .:    :::::  :::. ::. :::::::::.::::::: :::::... .: . .
CCDS61 RKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTKICKPVLLEGQVCSRRGHKDTAQ
        130       140       150       160       170       180      

     230       240       250       260         
pF1KB6 GLEIFQRCYCGEGLSCRIQKDHHQASNSSRLHTCQRH   
       . :::::: :: :: :: :   ..  . .::..::.    
CCDS61 APEIFQRCDCGPGLLCRSQLTSNR--QHARLRVCQKIEKL
        190       200       210         220    




266 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 18:37:27 2016 done: Fri Nov  4 18:37:27 2016
 Total Scan time:  2.590 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]