FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6353, 266 aa 1>>>pF1KB6353 266 - 266 aa - 266 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0725+/-0.000371; mu= 16.1868+/- 0.023 mean_var=76.6657+/-15.767, 0's: 0 Z-trim(113.2): 133 B-trim: 33 in 1/54 Lambda= 0.146478 statistics sampled from 22242 (22426) to 22242 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.263), width: 16 Scan time: 6.880 The best scores are: opt bits E(85289) NP_002116 (OMIM: 604776) major histocompatibility ( 266) 1801 390.1 2.3e-108 XP_011512864 (OMIM: 604776) PREDICTED: major histo ( 276) 1782 386.1 3.8e-107 NP_002115 (OMIM: 126200,142857,180300,181000) majo ( 266) 1599 347.4 1.6e-95 XP_011546040 (OMIM: 126200,142857,180300,181000) P ( 266) 1591 345.7 5.3e-95 NP_001230894 (OMIM: 126200,142857,180300,181000) m ( 266) 1567 340.6 1.8e-93 NP_072049 (OMIM: 612735) major histocompatibility ( 266) 1553 337.7 1.4e-92 NP_001230891 (OMIM: 123400,126200,212750,604305) H ( 261) 1137 249.7 3.9e-66 NP_001230890 (OMIM: 123400,126200,212750,604305) H ( 269) 1136 249.5 4.7e-66 NP_001287719 (OMIM: 615161) HLA class II histocomp ( 264) 1125 247.2 2.3e-65 XP_005249108 (OMIM: 615161) PREDICTED: HLA class I ( 275) 1124 247.0 2.7e-65 NP_002114 (OMIM: 123400,126200,212750,604305) HLA ( 261) 1112 244.4 1.5e-64 XP_011512862 (OMIM: 615161) PREDICTED: HLA class I ( 256) 1102 242.3 6.5e-64 NP_002112 (OMIM: 142858) HLA class II histocompati ( 258) 1036 228.4 1e-59 NP_002111 (OMIM: 600629) HLA class II histocompati ( 273) 960 212.3 7.4e-55 XP_011512863 (OMIM: 615161) PREDICTED: HLA class I ( 219) 914 202.5 5.3e-52 NP_001185787 (OMIM: 615161) HLA class II histocomp ( 227) 914 202.6 5.5e-52 NP_620576 (OMIM: 104300,176100,176200,235200,61263 ( 260) 276 67.8 2.3e-11 NP_620578 (OMIM: 104300,176100,176200,235200,61263 ( 325) 276 67.9 2.7e-11 XP_011512845 (OMIM: 104300,176100,176200,235200,61 ( 348) 276 67.9 2.9e-11 NP_000401 (OMIM: 104300,176100,176200,235200,61263 ( 348) 276 67.9 2.9e-11 NP_001287678 (OMIM: 104300,176100,176200,235200,61 ( 337) 274 67.5 3.8e-11 XP_011507765 (OMIM: 600764) PREDICTED: major histo ( 254) 268 66.1 7.4e-11 NP_002109 (OMIM: 142856) HLA class II histocompati ( 263) 262 64.8 1.8e-10 NP_001522 (OMIM: 600764) major histocompatibility ( 341) 255 63.4 6.2e-10 NP_002110 (OMIM: 142930) HLA class II histocompati ( 250) 249 62.1 1.2e-09 NP_001229453 (OMIM: 142880) HLA class II histocomp ( 260) 243 60.8 2.9e-09 NP_291032 (OMIM: 142880) HLA class II histocompati ( 260) 243 60.8 2.9e-09 NP_001229454 (OMIM: 142880) HLA class II histocomp ( 260) 243 60.8 2.9e-09 NP_620573 (OMIM: 104300,176100,176200,235200,61263 ( 256) 236 59.3 8.1e-09 XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 236 59.4 1e-08 NP_620577 (OMIM: 104300,176100,176200,235200,61263 ( 246) 234 58.9 1e-08 NP_620572 (OMIM: 104300,176100,176200,235200,61263 ( 242) 233 58.7 1.2e-08 NP_620579 (OMIM: 104300,176100,176200,235200,61263 ( 168) 231 58.1 1.2e-08 NP_620575 (OMIM: 104300,176100,176200,235200,61263 ( 334) 234 59.0 1.3e-08 NP_002113 (OMIM: 146880,212750) HLA class II histo ( 255) 232 58.5 1.4e-08 NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 233 58.8 1.6e-08 NP_001176 (OMIM: 194460) zinc-alpha-2-glycoprotein ( 298) 231 58.3 1.9e-08 XP_016866304 (OMIM: 143110) PREDICTED: HLA class I ( 228) 229 57.8 2.1e-08 NP_001181928 (OMIM: 600764) major histocompatibili ( 296) 229 57.9 2.5e-08 XP_016866303 (OMIM: 143110) PREDICTED: HLA class I ( 324) 229 57.9 2.7e-08 NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 229 58.0 2.8e-08 XP_016866302 (OMIM: 143110) PREDICTED: HLA class I ( 388) 229 58.0 3.1e-08 XP_016866301 (OMIM: 143110) PREDICTED: HLA class I ( 420) 229 58.0 3.2e-08 XP_016866300 (OMIM: 143110) PREDICTED: HLA class I ( 431) 229 58.0 3.3e-08 XP_016866299 (OMIM: 143110) PREDICTED: HLA class I ( 435) 229 58.0 3.3e-08 NP_001091949 (OMIM: 143110) HLA class I histocompa ( 442) 229 58.0 3.4e-08 NP_064440 (OMIM: 613503) HLA class II histocompati ( 255) 224 56.8 4.7e-08 NP_005507 (OMIM: 143010) HLA class I histocompatib ( 358) 225 57.1 5.2e-08 XP_016866298 (OMIM: 143010) PREDICTED: HLA class I ( 359) 225 57.1 5.2e-08 XP_016866297 (OMIM: 143010) PREDICTED: HLA class I ( 399) 225 57.2 5.6e-08 >>NP_002116 (OMIM: 604776) major histocompatibility comp (266 aa) initn: 1801 init1: 1801 opt: 1801 Z-score: 2066.5 bits: 390.1 E(85289): 2.3e-108 Smith-Waterman score: 1801; 100.0% identity (100.0% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFKNQKGHSGLHPTGLVS :::::::::::::::::::::::::: NP_002 FLGAGLFIYFKNQKGHSGLHPTGLVS 250 260 >>XP_011512864 (OMIM: 604776) PREDICTED: major histocomp (276 aa) initn: 1782 init1: 1782 opt: 1782 Z-score: 2044.6 bits: 386.1 E(85289): 3.8e-107 Smith-Waterman score: 1782; 99.2% identity (99.2% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFKNQKGHSGLHPTGLVS :::::::::::::::::::::: : : XP_011 FLGAGLFIYFKNQKGHSGLHPTVLSSESLKERKRSC 250 260 270 >>NP_002115 (OMIM: 126200,142857,180300,181000) major hi (266 aa) initn: 1619 init1: 1599 opt: 1599 Z-score: 1835.8 bits: 347.4 E(85289): 1.6e-95 Smith-Waterman score: 1599; 88.7% identity (95.9% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI :::::::::: :. ::::::::::::::.:::::::: : : :::::::::::::: : . NP_002 MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECHFFNGTERVRFLDRYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV :::::..::::::::.:::::::::::::::::::.::. :::::::::::::: ::::: NP_002 YNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAVDTYCRHNYGVVESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG ::::.:::::::..:: :::::::::::.:::::::::::: :.::::::.::::::::: NP_002 QRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLNGQEEKAGMVSTGLIQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_002 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFKNQKGHSGLHPTGLVS ::::::::::.::::::::.:::..: NP_002 FLGAGLFIYFRNQKGHSGLQPTGFLS 250 260 >>XP_011546040 (OMIM: 126200,142857,180300,181000) PREDI (266 aa) initn: 1610 init1: 1591 opt: 1591 Z-score: 1826.6 bits: 345.7 E(85289): 5.3e-95 Smith-Waterman score: 1591; 88.7% identity (95.5% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI :::::::::: :: ::::::::::::::::::.:::: : ::.::::::::::.::.: . XP_011 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV ::::: .:::::::::::::::::: :: ::::::.:::::. ::: ::::::::::::: XP_011 YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG ::::.:.::::::.:: :::::::::::.::::::::::::::.:::::::::::::::: XP_011 QRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL ::::::::::::::::::::::::::::: :::::::::.:::::::::::::::::::: XP_011 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFKNQKGHSGLHPTGLVS ::::::::::.::::::::.:::..: XP_011 FLGAGLFIYFRNQKGHSGLQPTGFLS 250 260 >>NP_001230894 (OMIM: 126200,142857,180300,181000) major (266 aa) initn: 1587 init1: 1567 opt: 1567 Z-score: 1799.2 bits: 340.6 E(85289): 1.8e-93 Smith-Waterman score: 1567; 86.1% identity (95.9% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI ::::.::::: :: :::::::::::::::::::::::. . ::::::::::::.: : . NP_001 MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEYSTSECHFFNGTERVRYLDRYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV .::::..::::::::.:::::::::::::::::::.::..:. ::.:::::::: ::::: NP_001 HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG ::::.:::::::..:: :::::::::::.::::::::::::::.::::.::::::::.:: NP_001 QRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_001 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFKNQKGHSGLHPTGLVS ::::::::::.::::::::.: :..: NP_001 FLGAGLFIYFRNQKGHSGLQPRGFLS 250 260 >>NP_072049 (OMIM: 612735) major histocompatibility comp (266 aa) initn: 1553 init1: 1553 opt: 1553 Z-score: 1783.2 bits: 337.7 E(85289): 1.4e-92 Smith-Waterman score: 1553; 86.8% identity (94.7% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI :::::::::: .: :::::::::: ::.:::::::::. : ::::::::::::.: : . NP_072 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV .:::: ::::::::::::::::::: :: ::::::.::..:. ::.:::::::::::::: NP_072 HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG ::::.:.::::::.:: :::::::::::.::::::::::::::.:::::::::::::::: NP_072 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL ::::::::::::::::::::::::::::::: :::::::.:::::::::::::::::::: NP_072 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 190 200 210 220 230 240 250 260 pF1KB6 FLGAGLFIYFKNQKGHSGLHPTGLVS ::::::::::.::::::::.:::..: NP_072 FLGAGLFIYFRNQKGHSGLQPTGFLS 250 260 >>NP_001230891 (OMIM: 123400,126200,212750,604305) HLA c (261 aa) initn: 1137 init1: 1137 opt: 1137 Z-score: 1308.2 bits: 249.7 E(85289): 3.9e-66 Smith-Waterman score: 1137; 66.7% identity (84.1% similar) in 252 aa overlap (4-255:7-258) 10 20 30 40 50 pF1KB6 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLH :..::: : .:. : .::.:.: . :. :. : : :.: :::::::.. NP_001 MSWKKALRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 RDIYNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGES :.:::.:: .::::::::.:::: :: : :::::::::.:: .::::: ::::: . NP_001 RSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 FTVQRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLI :.:::::: ::. :.::..:.:::::::::. :::..:.::::::.::: :::::: :: NP_001 TTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 QNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVL .::::::: ::::: .:. :.::::.:::::. ::.::::::::::::::::::.::::: NP_001 RNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVL 190 200 210 220 230 240 240 250 260 pF1KB6 GLLFLGAGLFIYFKNQKGHSGLHPTGLVS ::.::: ::.:. ..::: NP_001 GLIFLGLGLIIHHRSQKGLLH 250 260 >>NP_001230890 (OMIM: 123400,126200,212750,604305) HLA c (269 aa) initn: 1172 init1: 1126 opt: 1136 Z-score: 1306.9 bits: 249.5 E(85289): 4.7e-66 Smith-Waterman score: 1136; 66.0% identity (81.3% similar) in 262 aa overlap (4-265:7-268) 10 20 30 40 50 pF1KB6 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLH :..:: .: .:. : .::: :: . :. :. : : :.: :::::::.. NP_001 MSWKKALRIPGDLRVATVTLMLAMLSSLLAEGRDSPEDFVFQFKGMCYFTNGTERVRLVT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 RDIYNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGES : :::.:: ::::::: ::::: ::::::::::::. :: :: .:: ::::: :. NP_001 RYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 FTVQRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLI .:::::: ::. :.::..:.:::::::::. ::::.:.::::::.::: :::::: :: NP_001 GILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 QNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVL .::::::: ::::: .:. :.::::.:::::. ::.:::::::::::::::::::::::: NP_001 RNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGVGGFVL 190 200 210 220 230 240 240 250 260 pF1KB6 GLLFLGAGLFIYFKNQKGHSGLHPTGLVS ::.::: ::.: ..::: .: :.::. NP_001 GLIFLGLGLIIRQRSQKGPQGPPPAGLLH 250 260 >>NP_001287719 (OMIM: 615161) HLA class II histocompatib (264 aa) initn: 1121 init1: 849 opt: 1125 Z-score: 1294.5 bits: 247.2 E(85289): 2.3e-65 Smith-Waterman score: 1125; 65.3% identity (82.4% similar) in 262 aa overlap (4-265:3-263) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI :..::: . : .:: :..::.:.: : : :: : : :.: ::::::: . : : NP_001 MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYI 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV ::.:: ::::::::..::::::: . : ::. :::::..::::: ::::: . :. NP_001 YNREEYGRFDSDVGEFQAVTELGR-SIEDWNNYKDFLEQERAAVDKVCRHNYEAELRTTL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG ::.::: ::. :.::..:.:::::::::. :::..:.::::::.::: ::::::.::.:: NP_001 QRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL ::::: ::::: .:. :..:::::::::. ::.::::::::::::::::::.:::::::. NP_001 DWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLI 180 190 200 210 220 230 250 260 pF1KB6 FLGAGLFIYFKNQKGHSGLHPTGLVS ::: ::.: ..::: : :.::. NP_001 FLGLGLIIRHRGQKGPRGPPPAGLLH 240 250 260 >>XP_005249108 (OMIM: 615161) PREDICTED: HLA class II hi (275 aa) initn: 1103 init1: 831 opt: 1124 Z-score: 1293.1 bits: 247.0 E(85289): 2.7e-65 Smith-Waterman score: 1124; 65.0% identity (82.1% similar) in 263 aa overlap (4-266:3-264) 10 20 30 40 50 60 pF1KB6 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI :..::: . : .:: :..::.:.: : : :: : : :.: ::::::: . : : XP_005 MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYI 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV ::.:: ::::::::..::::::: . : ::. :::::..::::: ::::: . :. XP_005 YNREEYGRFDSDVGEFQAVTELGR-SIEDWNNYKDFLEQERAAVDKVCRHNYEAELRTTL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG ::.::: ::. :.::..:.:::::::::. :::..:.::::::.::: ::::::.::.:: XP_005 QRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL ::::: ::::: .:. :..:::::::::. ::.::::::::::::::::::.:::::::. XP_005 DWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLI 180 190 200 210 220 230 250 260 pF1KB6 FLGAGLFIYFKNQKGHSGLHPTGLVS ::: ::.: ..::: : :.: .: XP_005 FLGLGLIIRHRGQKGPRGPPPAGNISAMIQSGERAQA 240 250 260 270 266 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:35:16 2016 done: Fri Nov 4 20:35:17 2016 Total Scan time: 6.880 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]