FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6356, 295 aa 1>>>pF1KB6356 295 - 295 aa - 295 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.8283+/-0.000903; mu= -2.4311+/- 0.054 mean_var=336.7306+/-68.466, 0's: 0 Z-trim(117.2): 12 B-trim: 182 in 1/53 Lambda= 0.069893 statistics sampled from 17941 (17951) to 17941 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.839), E-opt: 0.2 (0.551), width: 16 Scan time: 3.090 The best scores are: opt bits E(32554) CCDS42253.1 PLSCR3 gene_id:57048|Hs108|chr17 ( 295) 2118 226.3 2.2e-59 CCDS3135.1 PLSCR1 gene_id:5359|Hs108|chr3 ( 318) 1038 117.4 1.4e-26 CCDS75029.1 PLSCR2 gene_id:57047|Hs108|chr3 ( 293) 913 104.8 8.1e-23 CCDS56284.1 PLSCR2 gene_id:57047|Hs108|chr3 ( 297) 913 104.8 8.2e-23 CCDS3134.1 PLSCR2 gene_id:57047|Hs108|chr3 ( 224) 894 102.7 2.6e-22 CCDS46931.1 PLSCR5 gene_id:389158|Hs108|chr3 ( 271) 851 98.5 5.9e-21 CCDS82853.1 PLSCR5 gene_id:389158|Hs108|chr3 ( 259) 812 94.5 8.7e-20 CCDS3133.1 PLSCR4 gene_id:57088|Hs108|chr3 ( 329) 724 85.8 4.8e-17 >>CCDS42253.1 PLSCR3 gene_id:57048|Hs108|chr17 (295 aa) initn: 2118 init1: 2118 opt: 2118 Z-score: 1179.7 bits: 226.3 E(32554): 2.2e-59 Smith-Waterman score: 2118; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295) 10 20 30 40 50 60 pF1KB6 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQVPAPAPGFALFPSPGPVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQVPAPAPGFALFPSPGPVAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRSGAGQPLGQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRSGAGQPLGQAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDESRSVGRISKQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDESRSVGRISKQW 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 GGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGPSAVTS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGPSAVTS 250 260 270 280 290 >>CCDS3135.1 PLSCR1 gene_id:5359|Hs108|chr3 (318 aa) initn: 1090 init1: 956 opt: 1038 Z-score: 590.8 bits: 117.4 E(32554): 1.4e-26 Smith-Waterman score: 1038; 51.5% identity (73.6% similar) in 299 aa overlap (3-286:20-309) 10 20 30 pF1KB6 MAGYLPPKGYAPSP---PPPYPVTPG----YPEP-ALHPGPGQ :: ::. : :. :: : :: :: : : : ::: CCDS31 MDKQNSQMNASHPETNLPVGY-PPQ-YPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGP 10 20 30 40 50 40 50 60 70 80 pF1KB6 A--PVPAQVPAPAPGFALFPSPGPVALGSAA-PFLPLP----GVPSGLEFLVQIDQILIH : ::: : :. . .. .: .:.:. :..: : . : :::.: :::::::: CCDS31 AGFPVPNQ---PVYNQPVYNQP----VGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIH 60 70 80 90 100 110 90 100 110 120 130 140 pF1KB6 QKAERVETFLGWETCNRYELRSGAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDRE :. : .:.. :.:: :.::.... :: . :::...::.: ::: ::. .:. : .: CCDS31 QQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQE 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB6 VLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVV :. : :::.:. :::: :::.:.:::::. ::.:.::::: ::::.::. :. ::.. CCDS31 VITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKIS 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB6 GPCWTCGCGTDTNFEVKTRDESRSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKA ::: .:.: :..::.:. ::. ::.:::.: :..:::.::::.::.::::::::..:: CCDS31 GPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKA 240 250 260 270 280 290 270 280 290 pF1KB6 VLLGATFLIDYMFFEKRGGAGPSAVTS :..:: ::::.::::. : CCDS31 VMIGACFLIDFMFFESTGSQEQKSGVW 300 310 >>CCDS75029.1 PLSCR2 gene_id:57047|Hs108|chr3 (293 aa) initn: 963 init1: 876 opt: 913 Z-score: 523.1 bits: 104.8 E(32554): 8.1e-23 Smith-Waterman score: 932; 50.0% identity (73.5% similar) in 264 aa overlap (22-284:39-291) 10 20 30 40 50 pF1KB6 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQV-PAPAPGFA :: . : : : : .:.: :. : CCDS75 PGPPGHIVYPKHQAGHTGKQADHLGSQAFYPGRQHDYLVPPAGTAGIPVQNQPGRPEGVP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 LFPSPGPVALGSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRS .:.: : :: . : :::.: :::.:::::. : .:.....:. : ::... CCDS75 WMPAPPP----------PL-NCPPGLEYLSQIDMILIHQQIELLEVLFSFESSNMYEIKN 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 GAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEM . :: . :::..: : : ::: ::. .:..: :::. : :::.:.: :::: :::. CCDS75 SFGQRIYFAAEDTNFCIRNCCGRSRPFTLRITDNVGREVITLERPLRCNCCCCPCCLQEI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 EVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDES :.:::::. .:.: ::::: : ::.:.. :. ::.. ::: .:.: . ..::. . ::. CCDS75 EIQAPPGVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCIVCSCIAGVDFEITSLDEQ 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 RSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGP ::::::.:.:..:::.::::.::.::: ::::..:::..:: :::::::::. CCDS75 IVVGRISKHWSGFLREAFTDADNFGIQFPRDLDVKMKAVMIGACFLIDYMFFERTR 240 250 260 270 280 290 pF1KB6 SAVTS >>CCDS56284.1 PLSCR2 gene_id:57047|Hs108|chr3 (297 aa) initn: 963 init1: 876 opt: 913 Z-score: 523.0 bits: 104.8 E(32554): 8.2e-23 Smith-Waterman score: 932; 50.0% identity (73.5% similar) in 264 aa overlap (22-284:43-295) 10 20 30 40 50 pF1KB6 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQV-PAPAPGFA :: . : : : : .:.: :. : CCDS56 SRPPGHIVYPKHQAGHTGKQADHLGSQAFYPGRQHDYLVPPAGTAGIPVQNQPGRPEGVP 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB6 LFPSPGPVALGSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRS .:.: : :: . : :::.: :::.:::::. : .:.....:. : ::... CCDS56 WMPAPPP----------PL-NCPPGLEYLSQIDMILIHQQIELLEVLFSFESSNMYEIKN 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 GAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEM . :: . :::..: : : ::: ::. .:..: :::. : :::.:.: :::: :::. CCDS56 SFGQRIYFAAEDTNFCIRNCCGRSRPFTLRITDNVGREVITLERPLRCNCCCCPCCLQEI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 EVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDES :.:::::. .:.: ::::: : ::.:.. :. ::.. ::: .:.: . ..::. . ::. CCDS56 EIQAPPGVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCIVCSCIAGVDFEITSLDEQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 RSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGP ::::::.:.:..:::.::::.::.::: ::::..:::..:: :::::::::. CCDS56 IVVGRISKHWSGFLREAFTDADNFGIQFPRDLDVKMKAVMIGACFLIDYMFFERTR 250 260 270 280 290 pF1KB6 SAVTS >>CCDS3134.1 PLSCR2 gene_id:57047|Hs108|chr3 (224 aa) initn: 979 init1: 876 opt: 894 Z-score: 514.2 bits: 102.7 E(32554): 2.6e-22 Smith-Waterman score: 894; 54.8% identity (80.1% similar) in 221 aa overlap (64-284:3-222) 40 50 60 70 80 90 pF1KB6 GQAPVPAQVPAPAPGFALFPSPGPVALGSAAPFLPLPGVPSGLEFLVQIDQILIHQKAER :: :: . : :::.: :::.:::::. : CCDS31 MPAPPPPL-NCPPGLEYLSQIDMILIHQQIEL 10 20 30 100 110 120 130 140 150 pF1KB6 VETFLGWETCNRYELRSGAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDREVLRLL .:.....:. : ::.... :: . :::..: : : ::: ::. .:..: :::. : CCDS31 LEVLFSFESSNMYEIKNSFGQRIYFAAEDTNFCIRNCCGRSRPFTLRITDNVGREVITLE 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 RPLHCGCSCCPCGLQEMEVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWT :::.:.: :::: :::.:.:::::. .:.: ::::: : ::.:.. :. ::.. ::: . CCDS31 RPLRCNCCCCPCCLQEIEIQAPPGVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCIV 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 CGCGTDTNFEVKTRDESRSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKAVLLGA :.: . ..::. . ::. ::::::.:.:..:::.::::.::.::: ::::..:::..:: CCDS31 CSCIAGVDFEITSLDEQIVVGRISKHWSGFLREAFTDADNFGIQFPRDLDVKMKAVMIGA 160 170 180 190 200 210 280 290 pF1KB6 TFLIDYMFFEKRGGAGPSAVTS :::::::::. CCDS31 CFLIDYMFFERTR 220 >>CCDS46931.1 PLSCR5 gene_id:389158|Hs108|chr3 (271 aa) initn: 827 init1: 827 opt: 851 Z-score: 489.7 bits: 98.5 E(32554): 5.9e-21 Smith-Waterman score: 851; 49.2% identity (74.0% similar) in 258 aa overlap (31-283:14-265) 10 20 30 40 50 pF1KB6 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPG--PGQAPVPAQ-VPAPA-PGFALFPSPG :: :: :: : : .:: . :: . CCDS46 MASKDAQNQRRGLPGFLPG-APDPDQSLPASSNPGNQAWQLSL 10 20 30 40 60 70 80 90 100 110 pF1KB6 PVALGSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRSGAGQPL :. . ::: ..: :::.: :.: :.:::..: . .:: :: :.::.... :: . CCDS46 PLP----SSFLPTVSLPPGLEYLSQLDLIIIHQQVELLGMILGTETSNKYEIKNSLGQRI 50 60 70 80 90 120 130 140 150 160 170 pF1KB6 GQAAEESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSC-CPCGLQEMEVQAP :.::: : : :.. : .:..: . :::. . :::.:. :: ::: :::.:.::: CCDS46 YFAVEESICFNRTFCSTLRSCTLRITDNSGREVITVNRPLRCN-SCWCPCYLQELEIQAP 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB6 PGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDESRSVGR ::: .:.: : : ::::::.::.:... .:..:::: :::: :..::::: .:. ..:. CCDS46 PGTIVGYVTQKWDPFLPKFTIQNANKEDILKIVGPCVTCGCFGDVDFEVKTINEKLTIGK 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB6 ISKQWGGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGPSAVTS ::: :.:.: ...:.::.::.. : :::: :::...:: ::.:.:::: CCDS46 ISKYWSGFVNDVFTNADNFGIHVPADLDVTVKAAMIGACFLFDFMFFEHSLAGL 220 230 240 250 260 270 >>CCDS82853.1 PLSCR5 gene_id:389158|Hs108|chr3 (259 aa) initn: 774 init1: 774 opt: 812 Z-score: 468.7 bits: 94.5 E(32554): 8.7e-20 Smith-Waterman score: 812; 49.2% identity (75.0% similar) in 248 aa overlap (38-283:13-253) 10 20 30 40 50 60 pF1KB6 KGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQVP-APAPGFALFPSPGPVALGSAAPF .:. .: :: : .: : .: :. : CCDS82 MASKDAQNQRRGLPGFLPGAPDPDQSLPASSNP---GNQAWQ 10 20 30 70 80 90 100 110 120 pF1KB6 LPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRSGAGQPLGQAAEESNCC : :: .::. :: .: :.:::..: . .:: :: :.::.... :: . :.::: : CCDS82 LSLP-LPSS--FLPTLDLIIIHQQVELLGMILGTETSNKYEIKNSLGQRIYFAVEESICF 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 ARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSC-CPCGLQEMEVQAPPGTTIGHVLQ : :.. : .:..: . :::. . :::.:. :: ::: :::.:.:::::: .:.: : CCDS82 NRTFCSTLRSCTLRITDNSGREVITVNRPLRCN-SCWCPCYLQELEIQAPPGTIVGYVTQ 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 TWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDESRSVGRISKQWGGLVR : ::::::.::.:... .:..:::: :::: :..::::: .:. ..:.::: :.:.: CCDS82 KWDPFLPKFTIQNANKEDILKIVGPCVTCGCFGDVDFEVKTINEKLTIGKISKYWSGFVN 160 170 180 190 200 210 250 260 270 280 290 pF1KB6 EALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGPSAVTS ...:.::.::.. : :::: :::...:: ::.:.:::: CCDS82 DVFTNADNFGIHVPADLDVTVKAAMIGACFLFDFMFFEHSLAGL 220 230 240 250 >>CCDS3133.1 PLSCR4 gene_id:57088|Hs108|chr3 (329 aa) initn: 737 init1: 319 opt: 724 Z-score: 419.5 bits: 85.8 E(32554): 4.8e-17 Smith-Waterman score: 724; 39.2% identity (63.9% similar) in 296 aa overlap (4-284:37-322) 10 20 pF1KB6 MAGYLP-PKGYAPSPPPPYP-------VTPGYP .:: : : : :: :: .: : CCDS31 TAPEQPAGEMENQTKPPDPRPDAPPEYNSHFLPGPPGTAVPPPTGYPGGLPMGYYSPQQP 10 20 30 40 50 60 30 40 50 60 70 80 pF1KB6 E--PALHPGPGQAPV---PAQVPAPAPGFALFPSPGPVALGSAAPFLPLPGVPSGLEFLV : .: : :: :.. : : . . :::. :. . : :::.:: CCDS31 STFPLYQPVGGIHPVRYQPGKYPMPNQSVPITWMPGPT---------PMANCPPGLEYLV 70 80 90 100 110 90 100 110 120 130 140 pF1KB6 QIDQILIHQKAERVETFLGWETCNRYELRSGAGQPLGQAAEESNCCARLCCGARRPLRVR :.:.: . :. : .: . .:: :::...... : . ..:... .: . ::. .: CCDS31 QLDNIHVLQHFEPLEMMTCFETNNRYDIKNNSDQMVYIVTEDTDDFTRNAYRTLRPFVLR 120 130 140 150 160 170 150 160 170 180 190 pF1KB6 LADPGDREVLRLLRPLHCGCSC--CPCGLQEMEVQAPPGTTIGHVLQTWHPFLPKFSIQD ..: ::.. . ::..: : : :: . ::.::: :::.::: : . :. .:::. CCDS31 VTDCMGREIMTMQRPFRCTCCCFCCPSARQELEVQCPPGVTIGFVAEHWNLCRAVYSIQN 180 190 200 210 220 230 200 210 220 230 240 250 pF1KB6 ADRQTVLRVVGPCWTCGCGTDTNFEVKTRDESRSVGRISKQWGGLVREALTDADDFGLQF ...:.:: ::: : :::.:. ::::. : ..: : ..:.::. :..::: : ..: CCDS31 EKKENVMRVRGPCSTYGCGSDSVFEVKSLDGISNIGSIIRKWNGLLS-AMADADHFDIHF 240 250 260 270 280 290 260 270 280 290 pF1KB6 PLDLDVRVKAVLLGATFLIDYMFFEKRGGAGPSAVTS ::::::..::...:: ::::.:.::. CCDS31 PLDLDVKMKAMIFGACFLIDFMYFERSPPQRSR 300 310 320 295 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:37:41 2016 done: Fri Nov 4 20:37:41 2016 Total Scan time: 3.090 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]