FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6356, 295 aa 1>>>pF1KB6356 295 - 295 aa - 295 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.4862+/-0.000364; mu= -6.7241+/- 0.023 mean_var=353.5136+/-73.076, 0's: 0 Z-trim(124.8): 45 B-trim: 841 in 1/58 Lambda= 0.068214 statistics sampled from 47135 (47183) to 47135 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.839), E-opt: 0.2 (0.553), width: 16 Scan time: 8.750 The best scores are: opt bits E(85289) NP_065093 (OMIM: 607611) phospholipid scramblase 3 ( 295) 2118 221.3 1.8e-57 NP_001188505 (OMIM: 607611) phospholipid scramblas ( 295) 2118 221.3 1.8e-57 XP_011511207 (OMIM: 604170) PREDICTED: phospholipi ( 311) 1038 115.1 1.8e-25 XP_016862118 (OMIM: 604170) PREDICTED: phospholipi ( 318) 1038 115.1 1.8e-25 XP_011511206 (OMIM: 604170) PREDICTED: phospholipi ( 318) 1038 115.1 1.8e-25 NP_066928 (OMIM: 604170) phospholipid scramblase 1 ( 318) 1038 115.1 1.8e-25 XP_016862117 (OMIM: 604170) PREDICTED: phospholipi ( 319) 996 110.9 3.2e-24 NP_001186908 (OMIM: 607610) phospholipid scramblas ( 293) 913 102.7 8.7e-22 XP_016862394 (OMIM: 607610) PREDICTED: phospholipi ( 297) 913 102.7 8.8e-22 NP_001186907 (OMIM: 607610) phospholipid scramblas ( 297) 913 102.7 8.8e-22 XP_016862398 (OMIM: 607610) PREDICTED: phospholipi ( 297) 913 102.7 8.8e-22 XP_016862395 (OMIM: 607610) PREDICTED: phospholipi ( 297) 913 102.7 8.8e-22 XP_016862397 (OMIM: 607610) PREDICTED: phospholipi ( 297) 913 102.7 8.8e-22 XP_016862396 (OMIM: 607610) PREDICTED: phospholipi ( 297) 913 102.7 8.8e-22 XP_011511315 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_016862392 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_016862391 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_016862388 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_016862393 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_016862387 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_011511323 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_011511321 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_011511322 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_011511324 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_016862389 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_016862390 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_011511325 (OMIM: 607610) PREDICTED: phospholipi ( 325) 913 102.8 9.4e-22 XP_016862399 (OMIM: 607610) PREDICTED: phospholipi ( 224) 894 100.8 2.6e-21 XP_016862400 (OMIM: 607610) PREDICTED: phospholipi ( 224) 894 100.8 2.6e-21 XP_016862404 (OMIM: 607610) PREDICTED: phospholipi ( 224) 894 100.8 2.6e-21 NP_065092 (OMIM: 607610) phospholipid scramblase 2 ( 224) 894 100.8 2.6e-21 XP_016862403 (OMIM: 607610) PREDICTED: phospholipi ( 224) 894 100.8 2.6e-21 XP_005247595 (OMIM: 604170) PREDICTED: phospholipi ( 237) 894 100.8 2.7e-21 XP_011511208 (OMIM: 604170) PREDICTED: phospholipi ( 237) 894 100.8 2.7e-21 XP_011511209 (OMIM: 604170) PREDICTED: phospholipi ( 237) 894 100.8 2.7e-21 XP_016862401 (OMIM: 607610) PREDICTED: phospholipi ( 222) 845 95.9 7.4e-20 XP_005247712 (OMIM: 607612) PREDICTED: phospholipi ( 329) 724 84.2 3.8e-16 XP_005247711 (OMIM: 607612) PREDICTED: phospholipi ( 329) 724 84.2 3.8e-16 NP_065086 (OMIM: 607612) phospholipid scramblase 4 ( 329) 724 84.2 3.8e-16 XP_011511333 (OMIM: 607612) PREDICTED: phospholipi ( 329) 724 84.2 3.8e-16 NP_001121777 (OMIM: 607612) phospholipid scramblas ( 329) 724 84.2 3.8e-16 NP_001121776 (OMIM: 607612) phospholipid scramblas ( 329) 724 84.2 3.8e-16 NP_001170775 (OMIM: 607612) phospholipid scramblas ( 224) 437 55.8 9.1e-08 NP_001121778 (OMIM: 607612) phospholipid scramblas ( 239) 437 55.8 9.5e-08 XP_016862410 (OMIM: 607612) PREDICTED: phospholipi ( 239) 437 55.8 9.5e-08 >>NP_065093 (OMIM: 607611) phospholipid scramblase 3 [Ho (295 aa) initn: 2118 init1: 2118 opt: 2118 Z-score: 1153.0 bits: 221.3 E(85289): 1.8e-57 Smith-Waterman score: 2118; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295) 10 20 30 40 50 60 pF1KB6 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQVPAPAPGFALFPSPGPVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQVPAPAPGFALFPSPGPVAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRSGAGQPLGQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRSGAGQPLGQAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDESRSVGRISKQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDESRSVGRISKQW 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 GGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGPSAVTS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGPSAVTS 250 260 270 280 290 >>NP_001188505 (OMIM: 607611) phospholipid scramblase 3 (295 aa) initn: 2118 init1: 2118 opt: 2118 Z-score: 1153.0 bits: 221.3 E(85289): 1.8e-57 Smith-Waterman score: 2118; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295) 10 20 30 40 50 60 pF1KB6 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQVPAPAPGFALFPSPGPVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQVPAPAPGFALFPSPGPVAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRSGAGQPLGQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRSGAGQPLGQAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDESRSVGRISKQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDESRSVGRISKQW 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 GGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGPSAVTS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGPSAVTS 250 260 270 280 290 >>XP_011511207 (OMIM: 604170) PREDICTED: phospholipid sc (311 aa) initn: 1090 init1: 956 opt: 1038 Z-score: 578.3 bits: 115.1 E(85289): 1.8e-25 Smith-Waterman score: 1038; 51.5% identity (73.6% similar) in 299 aa overlap (3-286:13-302) 10 20 30 40 pF1KB6 MAGYLPPKGYAPSP---PPPYPVTPG----YPEP-ALHPGPGQA--PVPA :: ::. : :. :: : :: :: : : : ::: : ::: XP_011 MNASHPETNLPVGY-PPQ-YPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAGFPVPN 10 20 30 40 50 50 60 70 80 90 pF1KB6 QVPAPAPGFALFPSPGPVALGSAA-PFLPLP----GVPSGLEFLVQIDQILIHQKAERVE : :. . .. .: .:.:. :..: : . : :::.: :::::::::. : .: XP_011 Q---PVYNQPVYNQP----VGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIELLE 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 TFLGWETCNRYELRSGAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDREVLRLLRP .. :.:: :.::.... :: . :::...::.: ::: ::. .:. : .::. : :: XP_011 VLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERP 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 LHCGCSCCPCGLQEMEVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCG :.:. :::: :::.:.:::::. ::.:.::::: ::::.::. :. ::.. ::: .:. XP_011 LRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCS 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB6 CGTDTNFEVKTRDESRSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKAVLLGATF : :..::.:. ::. ::.:::.: :..:::.::::.::.::::::::..:::..:: : XP_011 CCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACF 240 250 260 270 280 290 280 290 pF1KB6 LIDYMFFEKRGGAGPSAVTS :::.::::. : XP_011 LIDFMFFESTGSQEQKSGVW 300 310 >>XP_016862118 (OMIM: 604170) PREDICTED: phospholipid sc (318 aa) initn: 1090 init1: 956 opt: 1038 Z-score: 578.1 bits: 115.1 E(85289): 1.8e-25 Smith-Waterman score: 1038; 51.5% identity (73.6% similar) in 299 aa overlap (3-286:20-309) 10 20 30 pF1KB6 MAGYLPPKGYAPSP---PPPYPVTPG----YPEP-ALHPGPGQ :: ::. : :. :: : :: :: : : : ::: XP_016 MDKQNSQMNASHPETNLPVGY-PPQ-YPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGP 10 20 30 40 50 40 50 60 70 80 pF1KB6 A--PVPAQVPAPAPGFALFPSPGPVALGSAA-PFLPLP----GVPSGLEFLVQIDQILIH : ::: : :. . .. .: .:.:. :..: : . : :::.: :::::::: XP_016 AGFPVPNQ---PVYNQPVYNQP----VGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIH 60 70 80 90 100 110 90 100 110 120 130 140 pF1KB6 QKAERVETFLGWETCNRYELRSGAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDRE :. : .:.. :.:: :.::.... :: . :::...::.: ::: ::. .:. : .: XP_016 QQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQE 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB6 VLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVV :. : :::.:. :::: :::.:.:::::. ::.:.::::: ::::.::. :. ::.. XP_016 VITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKIS 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB6 GPCWTCGCGTDTNFEVKTRDESRSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKA ::: .:.: :..::.:. ::. ::.:::.: :..:::.::::.::.::::::::..:: XP_016 GPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKA 240 250 260 270 280 290 270 280 290 pF1KB6 VLLGATFLIDYMFFEKRGGAGPSAVTS :..:: ::::.::::. : XP_016 VMIGACFLIDFMFFESTGSQEQKSGVW 300 310 >>XP_011511206 (OMIM: 604170) PREDICTED: phospholipid sc (318 aa) initn: 1090 init1: 956 opt: 1038 Z-score: 578.1 bits: 115.1 E(85289): 1.8e-25 Smith-Waterman score: 1038; 51.5% identity (73.6% similar) in 299 aa overlap (3-286:20-309) 10 20 30 pF1KB6 MAGYLPPKGYAPSP---PPPYPVTPG----YPEP-ALHPGPGQ :: ::. : :. :: : :: :: : : : ::: XP_011 MDKQNSQMNASHPETNLPVGY-PPQ-YPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGP 10 20 30 40 50 40 50 60 70 80 pF1KB6 A--PVPAQVPAPAPGFALFPSPGPVALGSAA-PFLPLP----GVPSGLEFLVQIDQILIH : ::: : :. . .. .: .:.:. :..: : . : :::.: :::::::: XP_011 AGFPVPNQ---PVYNQPVYNQP----VGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIH 60 70 80 90 100 110 90 100 110 120 130 140 pF1KB6 QKAERVETFLGWETCNRYELRSGAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDRE :. : .:.. :.:: :.::.... :: . :::...::.: ::: ::. .:. : .: XP_011 QQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQE 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB6 VLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVV :. : :::.:. :::: :::.:.:::::. ::.:.::::: ::::.::. :. ::.. XP_011 VITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKIS 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB6 GPCWTCGCGTDTNFEVKTRDESRSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKA ::: .:.: :..::.:. ::. ::.:::.: :..:::.::::.::.::::::::..:: XP_011 GPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKA 240 250 260 270 280 290 270 280 290 pF1KB6 VLLGATFLIDYMFFEKRGGAGPSAVTS :..:: ::::.::::. : XP_011 VMIGACFLIDFMFFESTGSQEQKSGVW 300 310 >>NP_066928 (OMIM: 604170) phospholipid scramblase 1 [Ho (318 aa) initn: 1090 init1: 956 opt: 1038 Z-score: 578.1 bits: 115.1 E(85289): 1.8e-25 Smith-Waterman score: 1038; 51.5% identity (73.6% similar) in 299 aa overlap (3-286:20-309) 10 20 30 pF1KB6 MAGYLPPKGYAPSP---PPPYPVTPG----YPEP-ALHPGPGQ :: ::. : :. :: : :: :: : : : ::: NP_066 MDKQNSQMNASHPETNLPVGY-PPQ-YPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGP 10 20 30 40 50 40 50 60 70 80 pF1KB6 A--PVPAQVPAPAPGFALFPSPGPVALGSAA-PFLPLP----GVPSGLEFLVQIDQILIH : ::: : :. . .. .: .:.:. :..: : . : :::.: :::::::: NP_066 AGFPVPNQ---PVYNQPVYNQP----VGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIH 60 70 80 90 100 110 90 100 110 120 130 140 pF1KB6 QKAERVETFLGWETCNRYELRSGAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDRE :. : .:.. :.:: :.::.... :: . :::...::.: ::: ::. .:. : .: NP_066 QQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQE 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB6 VLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVV :. : :::.:. :::: :::.:.:::::. ::.:.::::: ::::.::. :. ::.. NP_066 VITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKIS 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB6 GPCWTCGCGTDTNFEVKTRDESRSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKA ::: .:.: :..::.:. ::. ::.:::.: :..:::.::::.::.::::::::..:: NP_066 GPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKA 240 250 260 270 280 290 270 280 290 pF1KB6 VLLGATFLIDYMFFEKRGGAGPSAVTS :..:: ::::.::::. : NP_066 VMIGACFLIDFMFFESTGSQEQKSGVW 300 310 >>XP_016862117 (OMIM: 604170) PREDICTED: phospholipid sc (319 aa) initn: 945 init1: 917 opt: 996 Z-score: 555.8 bits: 110.9 E(85289): 3.2e-24 Smith-Waterman score: 996; 50.5% identity (72.9% similar) in 295 aa overlap (3-282:20-305) 10 20 30 pF1KB6 MAGYLPPKGYAPSP---PPPYPVTPG----YPEP-ALHPGPGQ :: ::. : :. :: : :: :: : : : ::: XP_016 MDKQNSQMNASHPETNLPVGY-PPQ-YPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGP 10 20 30 40 50 40 50 60 70 80 pF1KB6 A--PVPAQVPAPAPGFALFPSPGPVALGSAA-PFLPLP----GVPSGLEFLVQIDQILIH : ::: : :. . .. .: .:.:. :..: : . : :::.: :::::::: XP_016 AGFPVPNQ---PVYNQPVYNQP----VGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIH 60 70 80 90 100 110 90 100 110 120 130 140 pF1KB6 QKAERVETFLGWETCNRYELRSGAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDRE :. : .:.. :.:: :.::.... :: . :::...::.: ::: ::. .:. : .: XP_016 QQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQE 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB6 VLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVV :. : :::.:. :::: :::.:.:::::. ::.:.::::: ::::.::. :. ::.. XP_016 VITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKIS 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB6 GPCWTCGCGTDTNFEVKTRDESRSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKA ::: .:.: :..::.:. ::. ::.:::.: :..:::.::::.::.::::::::..:: XP_016 GPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKA 240 250 260 270 280 290 270 280 290 pF1KB6 VLLGATFLIDYMFFEKRGGAGPSAVTS :..:: ::: .:. XP_016 VMIGACFLIVSLFLLILIIDAFSRFILK 300 310 >>NP_001186908 (OMIM: 607610) phospholipid scramblase 2 (293 aa) initn: 963 init1: 876 opt: 913 Z-score: 512.1 bits: 102.7 E(85289): 8.7e-22 Smith-Waterman score: 932; 50.0% identity (73.5% similar) in 264 aa overlap (22-284:39-291) 10 20 30 40 50 pF1KB6 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQV-PAPAPGFA :: . : : : : .:.: :. : NP_001 PGPPGHIVYPKHQAGHTGKQADHLGSQAFYPGRQHDYLVPPAGTAGIPVQNQPGRPEGVP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 LFPSPGPVALGSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRS .:.: : :: . : :::.: :::.:::::. : .:.....:. : ::... NP_001 WMPAPPP----------PL-NCPPGLEYLSQIDMILIHQQIELLEVLFSFESSNMYEIKN 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 GAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEM . :: . :::..: : : ::: ::. .:..: :::. : :::.:.: :::: :::. NP_001 SFGQRIYFAAEDTNFCIRNCCGRSRPFTLRITDNVGREVITLERPLRCNCCCCPCCLQEI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 EVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDES :.:::::. .:.: ::::: : ::.:.. :. ::.. ::: .:.: . ..::. . ::. NP_001 EIQAPPGVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCIVCSCIAGVDFEITSLDEQ 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 RSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGP ::::::.:.:..:::.::::.::.::: ::::..:::..:: :::::::::. NP_001 IVVGRISKHWSGFLREAFTDADNFGIQFPRDLDVKMKAVMIGACFLIDYMFFERTR 240 250 260 270 280 290 pF1KB6 SAVTS >>XP_016862394 (OMIM: 607610) PREDICTED: phospholipid sc (297 aa) initn: 963 init1: 876 opt: 913 Z-score: 512.0 bits: 102.7 E(85289): 8.8e-22 Smith-Waterman score: 932; 50.0% identity (73.5% similar) in 264 aa overlap (22-284:43-295) 10 20 30 40 50 pF1KB6 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQV-PAPAPGFA :: . : : : : .:.: :. : XP_016 SRPPGHIVYPKHQAGHTGKQADHLGSQAFYPGRQHDYLVPPAGTAGIPVQNQPGRPEGVP 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB6 LFPSPGPVALGSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRS .:.: : :: . : :::.: :::.:::::. : .:.....:. : ::... XP_016 WMPAPPP----------PL-NCPPGLEYLSQIDMILIHQQIELLEVLFSFESSNMYEIKN 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 GAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEM . :: . :::..: : : ::: ::. .:..: :::. : :::.:.: :::: :::. XP_016 SFGQRIYFAAEDTNFCIRNCCGRSRPFTLRITDNVGREVITLERPLRCNCCCCPCCLQEI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 EVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDES :.:::::. .:.: ::::: : ::.:.. :. ::.. ::: .:.: . ..::. . ::. XP_016 EIQAPPGVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCIVCSCIAGVDFEITSLDEQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 RSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGP ::::::.:.:..:::.::::.::.::: ::::..:::..:: :::::::::. XP_016 IVVGRISKHWSGFLREAFTDADNFGIQFPRDLDVKMKAVMIGACFLIDYMFFERTR 250 260 270 280 290 pF1KB6 SAVTS >>NP_001186907 (OMIM: 607610) phospholipid scramblase 2 (297 aa) initn: 963 init1: 876 opt: 913 Z-score: 512.0 bits: 102.7 E(85289): 8.8e-22 Smith-Waterman score: 932; 50.0% identity (73.5% similar) in 264 aa overlap (22-284:43-295) 10 20 30 40 50 pF1KB6 MAGYLPPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQV-PAPAPGFA :: . : : : : .:.: :. : NP_001 SRPPGHIVYPKHQAGHTGKQADHLGSQAFYPGRQHDYLVPPAGTAGIPVQNQPGRPEGVP 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB6 LFPSPGPVALGSAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRS .:.: : :: . : :::.: :::.:::::. : .:.....:. : ::... NP_001 WMPAPPP----------PL-NCPPGLEYLSQIDMILIHQQIELLEVLFSFESSNMYEIKN 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 GAGQPLGQAAEESNCCARLCCGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEM . :: . :::..: : : ::: ::. .:..: :::. : :::.:.: :::: :::. NP_001 SFGQRIYFAAEDTNFCIRNCCGRSRPFTLRITDNVGREVITLERPLRCNCCCCPCCLQEI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 EVQAPPGTTIGHVLQTWHPFLPKFSIQDADRQTVLRVVGPCWTCGCGTDTNFEVKTRDES :.:::::. .:.: ::::: : ::.:.. :. ::.. ::: .:.: . ..::. . ::. NP_001 EIQAPPGVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCIVCSCIAGVDFEITSLDEQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 RSVGRISKQWGGLVREALTDADDFGLQFPLDLDVRVKAVLLGATFLIDYMFFEKRGGAGP ::::::.:.:..:::.::::.::.::: ::::..:::..:: :::::::::. NP_001 IVVGRISKHWSGFLREAFTDADNFGIQFPRDLDVKMKAVMIGACFLIDYMFFERTR 250 260 270 280 290 pF1KB6 SAVTS 295 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:37:42 2016 done: Fri Nov 4 20:37:43 2016 Total Scan time: 8.750 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]