FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6357, 267 aa 1>>>pF1KB6357 267 - 267 aa - 267 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2243+/-0.000329; mu= 15.5800+/- 0.020 mean_var=69.3202+/-14.583, 0's: 0 Z-trim(115.6): 79 B-trim: 1044 in 1/49 Lambda= 0.154044 statistics sampled from 26066 (26145) to 26066 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.307), width: 16 Scan time: 7.050 The best scores are: opt bits E(85289) NP_002414 (OMIM: 178990) matrilysin preproprotein ( 267) 1825 414.3 1.2e-115 NP_004762 (OMIM: 604629,612529) matrix metalloprot ( 483) 862 200.4 5e-51 NP_002413 (OMIM: 185250,614466) stromelysin-1 prep ( 477) 845 196.7 6.8e-50 NP_002416 (OMIM: 185260) stromelysin-2 preproprote ( 476) 836 194.7 2.7e-49 NP_002418 (OMIM: 250400,600108,602111) collagenase ( 471) 823 191.8 2e-48 NP_002417 (OMIM: 601046) macrophage metalloelastas ( 470) 817 190.4 5e-48 NP_002412 (OMIM: 120353,226600,606963) interstitia ( 469) 801 186.9 5.9e-47 NP_002415 (OMIM: 120355) neutrophil collagenase is ( 467) 792 184.9 2.4e-46 XP_011541137 (OMIM: 120355) PREDICTED: neutrophil ( 444) 791 184.6 2.6e-46 XP_016873260 (OMIM: 120355) PREDICTED: neutrophil ( 444) 791 184.6 2.6e-46 NP_001291371 (OMIM: 120355) neutrophil collagenase ( 444) 791 184.6 2.6e-46 NP_001291370 (OMIM: 120355) neutrophil collagenase ( 444) 791 184.6 2.6e-46 XP_011541138 (OMIM: 120355) PREDICTED: neutrophil ( 377) 785 183.3 5.8e-46 XP_011541136 (OMIM: 120355) PREDICTED: neutrophil ( 476) 785 183.3 7e-46 NP_001139410 (OMIM: 120353,226600,606963) intersti ( 403) 765 178.8 1.3e-44 NP_068573 (OMIM: 605470) matrix metalloproteinase- ( 261) 675 158.7 9.9e-39 NP_004521 (OMIM: 120360,259600) 72 kDa type IV col ( 660) 659 155.4 2.5e-37 NP_001121363 (OMIM: 120360,259600) 72 kDa type IV ( 610) 627 148.3 3.2e-35 XP_011518521 (OMIM: 605470) PREDICTED: matrix meta ( 191) 597 141.3 1.3e-33 NP_001289437 (OMIM: 120360,259600) 72 kDa type IV ( 584) 588 139.6 1.3e-32 NP_001289439 (OMIM: 120360,259600) 72 kDa type IV ( 584) 588 139.6 1.3e-32 NP_001289438 (OMIM: 120360,259600) 72 kDa type IV ( 584) 588 139.6 1.3e-32 XP_016874796 (OMIM: 602285) PREDICTED: matrix meta ( 434) 554 132.0 1.9e-30 NP_057239 (OMIM: 602285) matrix metalloproteinase- ( 603) 554 132.1 2.4e-30 XP_011536657 (OMIM: 602285) PREDICTED: matrix meta ( 519) 542 129.4 1.4e-29 XP_011536658 (OMIM: 602285) PREDICTED: matrix meta ( 519) 542 129.4 1.4e-29 XP_011536659 (OMIM: 602285) PREDICTED: matrix meta ( 519) 542 129.4 1.4e-29 XP_011526802 (OMIM: 604871) PREDICTED: matrix meta ( 556) 534 127.6 4.9e-29 XP_016883087 (OMIM: 604871) PREDICTED: matrix meta ( 614) 534 127.6 5.3e-29 NP_006681 (OMIM: 604871) matrix metalloproteinase- ( 645) 534 127.6 5.6e-29 NP_002419 (OMIM: 602261) matrix metalloproteinase- ( 669) 519 124.3 5.8e-28 XP_016874798 (OMIM: 601807,611543) PREDICTED: matr ( 366) 507 121.5 2.3e-27 XP_016874797 (OMIM: 601807,611543) PREDICTED: matr ( 387) 507 121.5 2.4e-27 NP_002420 (OMIM: 601807,611543) matrix metalloprot ( 508) 507 121.6 2.9e-27 XP_011520906 (OMIM: 608482) PREDICTED: matrix meta ( 478) 499 119.8 9.6e-27 XP_011520904 (OMIM: 608482) PREDICTED: matrix meta ( 528) 499 119.8 1e-26 NP_071913 (OMIM: 608482) matrix metalloproteinase- ( 562) 499 119.8 1.1e-26 NP_005931 (OMIM: 185261) stromelysin-3 preproprote ( 488) 495 118.9 1.8e-26 NP_005932 (OMIM: 602262) matrix metalloproteinase- ( 607) 488 117.4 6.3e-26 NP_004985 (OMIM: 120361,613073) matrix metalloprot ( 707) 487 117.2 8.3e-26 NP_004986 (OMIM: 277950,600754) matrix metalloprot ( 582) 479 115.4 2.4e-25 XP_016880552 (OMIM: 608417) PREDICTED: matrix meta ( 378) 392 95.9 1.1e-19 XP_016880553 (OMIM: 608417) PREDICTED: matrix meta ( 378) 392 95.9 1.1e-19 XP_016880551 (OMIM: 608417) PREDICTED: matrix meta ( 378) 392 95.9 1.1e-19 XP_011523533 (OMIM: 608417) PREDICTED: matrix meta ( 390) 392 95.9 1.2e-19 NP_116568 (OMIM: 608417) matrix metalloproteinase- ( 393) 392 95.9 1.2e-19 XP_011523532 (OMIM: 608417) PREDICTED: matrix meta ( 418) 392 96.0 1.2e-19 XP_011523531 (OMIM: 608417) PREDICTED: matrix meta ( 435) 392 96.0 1.3e-19 XP_011523529 (OMIM: 608417) PREDICTED: matrix meta ( 435) 392 96.0 1.3e-19 XP_011523530 (OMIM: 608417) PREDICTED: matrix meta ( 435) 392 96.0 1.3e-19 >>NP_002414 (OMIM: 178990) matrilysin preproprotein [Hom (267 aa) initn: 1825 init1: 1825 opt: 1825 Z-score: 2197.4 bits: 414.3 E(85289): 1.2e-115 Smith-Waterman score: 1825; 99.6% identity (100.0% similar) in 267 aa overlap (1-267:1-267) 10 20 30 40 50 60 pF1KB6 MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EMQKFFGLPITGMLNSHVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: NP_002 EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD 190 200 210 220 230 240 250 260 pF1KB6 PQNFKLSQDDIKGIQKLYGKRSNSRKK ::::::::::::::::::::::::::: NP_002 PQNFKLSQDDIKGIQKLYGKRSNSRKK 250 260 >>NP_004762 (OMIM: 604629,612529) matrix metalloproteina (483 aa) initn: 855 init1: 623 opt: 862 Z-score: 1037.1 bits: 200.4 E(85289): 5e-51 Smith-Waterman score: 862; 51.7% identity (77.8% similar) in 234 aa overlap (35-261:41-273) 10 20 30 40 50 pF1KB6 VLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFY-------LYDSETKNANSLEA :: :: ..: . . ....::. NP_004 VFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIR 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB6 KLKEMQKFFGLPITGMLNSHVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYT :.::.: :::: .:: :.. ......::::::::::.: :::. ::: ....:::: .:: NP_004 KIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYT 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB6 RDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLA .. . ::. : ::. :.. .:: : .. : :::::.: : :::::::::: .::: NP_004 PSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLA 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB6 HAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYG :::::: :::::.:::. :.:: :.. :.:.. .:.::.::.::..::.::.:.::::: NP_004 HAFAPGEGLGGDTHFDNAEKWTMGTN-GFNLFTVAAHEFGHALGLAHSTDPSALMYPTYK 200 210 220 230 240 240 250 260 pF1KB6 NGDPQNFKLSQDDIKGIQKLYGKRSNSRKK .: .:.: .::.:::: ::: : NP_004 YKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVTMLG 250 260 270 280 290 300 >>NP_002413 (OMIM: 185250,614466) stromelysin-1 prepropr (477 aa) initn: 683 init1: 683 opt: 845 Z-score: 1016.7 bits: 196.7 E(85289): 6.8e-50 Smith-Waterman score: 845; 49.3% identity (71.9% similar) in 270 aa overlap (3-264:7-269) 10 20 30 40 50 pF1KB6 MRLTVLC-AVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETK----- : .:: ::: : :: : : . . . .: ::. .: ...: NP_002 MKSLPILLLLCVAVCS-----AYPLDGAARG-EDTSMNLVQKYLENYYDLKKDVKQFVRR 10 20 30 40 50 60 70 80 90 100 pF1KB6 -NANSLEAKLKEMQKFFGLPITGMLNSHVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVV ... . :..:::::.:: .:: :.: ..:.:.:::::::::... ::. ::: . . NP_002 KDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 TYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPF :::::.:: :::. .:: : :::..: . :: : .. : :::::.:: ::: ::: NP_002 TYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPF 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 DGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPN :::::.::::.::: :..::::::.::.:: .. : :.. .:.::.:::::. ::.. . NP_002 DGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTT-GTNLFLVAAHEIGHSLGLFHSANTE 180 190 200 210 220 230 230 240 250 260 pF1KB6 AVMYPTYGN-GDPQNFKLSQDDIKGIQKLYGKRSNSRKK :.::: : . : :.::::::.:::.::: .: NP_002 ALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPA 240 250 260 270 280 290 NP_002 LSFDAVSTLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVF 300 310 320 330 340 350 >>NP_002416 (OMIM: 185260) stromelysin-2 preproprotein [ (476 aa) initn: 641 init1: 641 opt: 836 Z-score: 1005.9 bits: 194.7 E(85289): 2.7e-49 Smith-Waterman score: 836; 48.3% identity (74.0% similar) in 265 aa overlap (1-259:2-263) 10 20 30 40 50 pF1KB6 MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETK-----NANS :.:. : .:: : : :: :. . . . ::.::...: ....: ..: NP_002 MMHLAFLVLLCL-PVCSAYPLSG-AAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNL 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 LEAKLKEMQKFFGLPITGMLNSHVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIV . :.. ::::.:: .:: :.. ..:.:.:::::::::...: ::. ::: . .::::: NP_002 IVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 SYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGN .:: :::. .:: . :::..: . :: : .. : :::::.:: ::: : :::::. NP_002 NYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGH 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 TLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYP .::::. :: :: :: :::.::.::. .: : :.. .:.::::::::. ::.. .:.::: NP_002 SLAHAYPPGPGLYGDIHFDDDEKWTEDAS-GTNLFLVAAHELGHSLGLFHSANTEALMYP 180 190 200 210 220 230 240 250 260 pF1KB6 TYGN-GDPQNFKLSQDDIKGIQKLYGKRSNSRKK :.. . .:.:::::..:::.::: NP_002 LYNSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDA 240 250 260 270 280 290 >>NP_002418 (OMIM: 250400,600108,602111) collagenase 3 p (471 aa) initn: 655 init1: 601 opt: 823 Z-score: 990.4 bits: 191.8 E(85289): 2e-48 Smith-Waterman score: 823; 48.4% identity (74.6% similar) in 252 aa overlap (17-259:19-267) 10 20 30 40 pF1KB6 MRLTVLCAVCLLPGSLALPLPQEAGG----MSELQWEQAQDYLKRFYLYDS-----ET ::::: .:: .:: . . :. ::. .: . . NP_002 MHPGVLAAFLFLSWTHCRALPLP--SGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKE 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 KNANSLEAKLKEMQKFFGLPITGMLNSHVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVV . :.:. .:.:::.:::: .:: :.......:.:::::::::.::..:: . ::.. . NP_002 NAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 TYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPF :::::.:: :. : :.. .::...:. ::.: .. : :::::.:. ::: ::: NP_002 TYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPF 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 DGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPN :::.. ::::: :: . :::::::.:: ::. :: : :.. .:.::.:::::. ::.::. NP_002 DGPSGLLAHAFPPGPNYGGDAHFDDDETWTS-SSKGYNLFLVAAHEFGHSLGLDHSKDPG 180 190 200 210 220 230 230 240 250 260 pF1KB6 AVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK :.:.: : ..: : .::..:::.::: NP_002 ALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLR 240 250 260 270 280 290 >>NP_002417 (OMIM: 601046) macrophage metalloelastase pr (470 aa) initn: 787 init1: 571 opt: 817 Z-score: 983.2 bits: 190.4 E(85289): 5e-48 Smith-Waterman score: 817; 48.3% identity (75.3% similar) in 259 aa overlap (15-265:14-270) 10 20 30 40 50 pF1KB6 MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFY------LYDSETK-NAN : :::: . . .. . . .. ::..:: : .. : ..: NP_002 MKFLLILLLQATASGALPL-NSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGN 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 SLEAKLKEMQKFFGLPITGMLNSHVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRI .. :..:::.:.:: .::.:.. ..:.:. :::::::: .. .:..: : .. .:::: NP_002 LMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRI 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 VSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPG .:: :. . :: . ::...:.. ::.: :. : :::.. :::::::: . ::: : NP_002 NNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 NTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMY . :::::.::.:.:::::::::: :: :. : :.. .:.::.:::::.::::::.:::. NP_002 GILAHAFGPGSGIGGDAHFDEDEFWTTHSG-GTNLFLTAVHEIGHSLGLGHSSDPKAVMF 180 190 200 210 220 230 240 250 260 pF1KB6 PTYGNGDPQNFKLSQDDIKGIQKLYGK-RSNSRKK ::: : ..:.:: :::.:::.::: . :.: NP_002 PTYKYVDINTFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNK 240 250 260 270 280 290 NP_002 IFFFKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISN 300 310 320 330 340 350 >>NP_002412 (OMIM: 120353,226600,606963) interstitial co (469 aa) initn: 777 init1: 609 opt: 801 Z-score: 964.0 bits: 186.9 E(85289): 5.9e-47 Smith-Waterman score: 801; 49.2% identity (74.8% similar) in 242 aa overlap (29-263:28-265) 10 20 30 40 50 pF1KB6 MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSE------TKNANS : . . .: ::...: .. .:.. NP_002 MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGP 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 LEAKLKEMQKFFGLPITGMLNSHVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIV . :::.::.:::: .:: .......:..:::::::::.. : ..:.: . .:::: NP_002 VVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 SYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGN .:: :::. ::. . ::...:.. :: : :: : :::::.:.:: : :. ::::::. NP_002 NYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 TLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYP .::::: :: :.:::::::::::::.. :. .:.::::::::..::.: .:.::: NP_002 NLAHAFQPGPGIGGDAHFDEDERWTNNFRE-YNLHRVAAHELGHSLGLSHSTDIGALMYP 180 190 200 210 220 230 240 250 260 pF1KB6 TYG-NGDPQNFKLSQDDIKGIQKLYGKRSNSRKK .: .:: : :.:::: ::: .::. .: NP_002 SYTFSGDVQ---LAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVM 240 250 260 270 280 290 >>NP_002415 (OMIM: 120355) neutrophil collagenase isofor (467 aa) initn: 569 init1: 548 opt: 792 Z-score: 953.2 bits: 184.9 E(85289): 2.4e-46 Smith-Waterman score: 792; 50.0% identity (73.9% similar) in 234 aa overlap (36-263:34-266) 10 20 30 40 50 pF1KB6 LCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYL-----YDSETKNA-NSLEAKL ::::..:: :.: ::. : . :: NP_002 LKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIVEKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 KEMQKFFGLPITGMLNSHVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRD ::::.:::: .:: : .....:.:::::::: . . : :..::: .:::: .:: . NP_002 KEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNYTPQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 LPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHA : . :.: .. :...:. :: : .. : ::: :.: . :::. :::::.. :::: NP_002 LSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 FAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNG : :: :.::::::: .: ::. .: . :.. .:.::.:::::..:::::.:.:::.:. NP_002 FQPGQGIGGDAHFDAEETWTN-TSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFR 190 200 210 220 230 240 240 250 260 pF1KB6 DPQNFKLSQDDIKGIQKLYGKRSNSRKK . .:..: :::: ::: .:: :: NP_002 ETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKDRY 250 260 270 280 290 300 >>XP_011541137 (OMIM: 120355) PREDICTED: neutrophil coll (444 aa) initn: 569 init1: 548 opt: 791 Z-score: 952.3 bits: 184.6 E(85289): 2.6e-46 Smith-Waterman score: 791; 48.4% identity (73.8% similar) in 244 aa overlap (27-263:1-243) 10 20 30 40 50 pF1KB6 MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQA-QDYLKRFYL-----YDSETKNA-N :... :.. .:::..:: :.: ::. : XP_011 MQQIPQEKSINDYLEKFYQLPSNQYQSTRKNGTN 10 20 30 60 70 80 90 100 110 pF1KB6 SLEAKLKEMQKFFGLPITGMLNSHVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRI . ::::::.:::: .:: : .....:.:::::::: . . : :..::: .:::: XP_011 VIVEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRI 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB6 VSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPG .:: .: . :.: .. :...:. :: : .. : ::: :.: . :::. :::::. XP_011 RNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPN 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB6 NTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMY . ::::: :: :.::::::: .: ::. .: . :.. .:.::.:::::..:::::.:.:: XP_011 GILAHAFQPGQGIGGDAHFDAEETWTN-TSANYNLFLVAAHEFGHSLGLAHSSDPGALMY 160 170 180 190 200 210 240 250 260 pF1KB6 PTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK :.:. . .:..: :::: ::: .:: :: XP_011 PNYAFRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEIL 220 230 240 250 260 270 >>XP_016873260 (OMIM: 120355) PREDICTED: neutrophil coll (444 aa) initn: 569 init1: 548 opt: 791 Z-score: 952.3 bits: 184.6 E(85289): 2.6e-46 Smith-Waterman score: 791; 48.4% identity (73.8% similar) in 244 aa overlap (27-263:1-243) 10 20 30 40 50 pF1KB6 MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQA-QDYLKRFYL-----YDSETKNA-N :... :.. .:::..:: :.: ::. : XP_016 MQQIPQEKSINDYLEKFYQLPSNQYQSTRKNGTN 10 20 30 60 70 80 90 100 110 pF1KB6 SLEAKLKEMQKFFGLPITGMLNSHVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRI . ::::::.:::: .:: : .....:.:::::::: . . : :..::: .:::: XP_016 VIVEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRI 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB6 VSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPG .:: .: . :.: .. :...:. :: : .. : ::: :.: . :::. :::::. XP_016 RNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPN 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB6 NTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMY . ::::: :: :.::::::: .: ::. .: . :.. .:.::.:::::..:::::.:.:: XP_016 GILAHAFQPGQGIGGDAHFDAEETWTN-TSANYNLFLVAAHEFGHSLGLAHSSDPGALMY 160 170 180 190 200 210 240 250 260 pF1KB6 PTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK :.:. . .:..: :::: ::: .:: :: XP_016 PNYAFRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEIL 220 230 240 250 260 270 267 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:00:19 2016 done: Sat Nov 5 08:00:20 2016 Total Scan time: 7.050 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]