Result of FASTA (ccds) for
pF1KB6358
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6358, 296 aa
1>>>pF1KB6358 296 - 296 aa - 296 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3944+/-0.000685; mu= 11.3291+/- 0.042
mean_var=107.7842+/-21.340, 0's: 0 Z-trim(113.2): 18 B-trim: 0 in 0/52
Lambda= 0.123537
statistics sampled from 13841 (13856) to 13841 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.426), width: 16
Scan time: 2.580
The best scores are: opt bits E(32554)
CCDS130.1 FBXO2 gene_id:26232|Hs108|chr1 ( 296) 2084 381.4 4.4e-106
CCDS133.1 FBXO6 gene_id:26270|Hs108|chr1 ( 293) 895 169.5 2.7e-42
CCDS132.1 FBXO44 gene_id:93611|Hs108|chr1 ( 255) 867 164.5 7.7e-41
CCDS12527.1 FBXO27 gene_id:126433|Hs108|chr19 ( 283) 664 128.3 6.5e-30
CCDS12526.1 FBXO17 gene_id:115290|Hs108|chr19 ( 278) 501 99.3 3.5e-21
CCDS131.1 FBXO44 gene_id:93611|Hs108|chr1 ( 224) 367 75.3 4.6e-14
CCDS12529.1 NCCRP1 gene_id:342897|Hs108|chr19 ( 275) 366 75.2 6.2e-14
CCDS81261.1 FBXO44 gene_id:93611|Hs108|chr1 ( 256) 363 74.6 8.4e-14
>>CCDS130.1 FBXO2 gene_id:26232|Hs108|chr1 (296 aa)
initn: 2084 init1: 2084 opt: 2084 Z-score: 2018.0 bits: 381.4 E(32554): 4.4e-106
Smith-Waterman score: 2084; 100.0% identity (100.0% similar) in 296 aa overlap (1-296:1-296)
10 20 30 40 50 60
pF1KB6 MDGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MDGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 ALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHDESVKKYFASSFEWCRKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHDESVKKYFASSFEWCRKAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVA
190 200 210 220 230 240
250 260 270 280 290
pF1KB6 VPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWVEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWVEP
250 260 270 280 290
>>CCDS133.1 FBXO6 gene_id:26270|Hs108|chr1 (293 aa)
initn: 835 init1: 299 opt: 895 Z-score: 872.8 bits: 169.5 E(32554): 2.7e-42
Smith-Waterman score: 895; 50.2% identity (72.9% similar) in 255 aa overlap (42-296:8-259)
20 30 40 50 60 70
pF1KB6 QPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAALPAAELVQAC
:: ..:::: .::.... .:: .:. :
CCDS13 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNC
10 20 30
80 90 100 110 120 130
pF1KB6 RLVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRRRNLLRNPCGEE
:::: :..:.: :: :: .::.. . . : :. :::: . .::::::::.::
CCDS13 RLVCSLWRDLIDLMTLWKRKCLREGFITKDWDQPVAD-WKIFYFLRSLHRNLLRNPCAEE
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 DLEGWCDVEHGGDGWRVEELPGDSGVEFTHDESVKKYFASSFEWCRKAQVIDLQAEGYWE
:. .: .::: :.:: ::: :..: : .:::::..:.: : :.:..:: ::::::
CCDS13 DMFAWQIDFNGGDRWKVESLPGAHGTDFP-DPKVKKYFVTSYEMCLKSQLVDLVAEGYWE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB6 ELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVAVPQDSDGGGWM
::::: .: ::::::...:.: :: :.: :.: : ::: : :.. :. ... :
CCDS13 ELLDTFRPDIVVKDWFAARADCGCTYQLKVQLASADYFVLASFEPPPVTI-QQWNNATWT
160 170 180 190 200 210
260 270 280 290
pF1KB6 EISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWVEP
:.:.::.:: :::.. :.:::.:. :: ::.: ::::::. : :
CCDS13 EVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQ
220 230 240 250 260 270
CCDS13 KHGQEEAAQSPYRAVVQIF
280 290
>>CCDS132.1 FBXO44 gene_id:93611|Hs108|chr1 (255 aa)
initn: 672 init1: 298 opt: 867 Z-score: 846.7 bits: 164.5 E(32554): 7.7e-41
Smith-Waterman score: 867; 49.4% identity (73.7% similar) in 255 aa overlap (43-296:2-252)
20 30 40 50 60 70
pF1KB6 PEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAALPAAELVQACR
:.. ..:::: .::.... .:: .:. ::
CCDS13 MAVGNINELPENILLELFTHVPARQLLLNCR
10 20 30
80 90 100 110 120 130
pF1KB6 LVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRRRNLLRNPCGEED
::: :..:.: . :: :: .::.. : . : :. :::: . .::::.:::.::
CCDS13 LVCSLWRDLIDLVTLWKRKCLREGFITEDWDQPVAD-WKIFYFLRSLHRNLLHNPCAEEG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 LEGWC-DVEHGGDGWRVEELPGDSGVEFTHDESVKKYFASSFEWCRKAQVIDLQAEGYWE
.: : :: .::: :.::.: :. :: .:. :::::..:. : :.::.::.::::::
CCDS13 FEFWSLDV-NGGDEWKVEDLSRDQRKEFPNDQ-VKKYFVTSYYTCLKSQVVDLKAEGYWE
100 110 120 130 140
200 210 220 230 240 250
pF1KB6 ELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVAVPQDSDGGGWM
::.:::.: : ::::...: : : :.: :.::: . :. :. ... : ::. :
CCDS13 ELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLLSSAHAPLGTFQPDPATIQQKSDAK-WR
150 160 170 180 190 200
260 270 280 290
pF1KB6 EISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWVEP
:.::::..: ::::.. :.::: :. :: ::.: ::::::. . :
CCDS13 EVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGPRVTNSSITIGPPLP
210 220 230 240 250
>>CCDS12527.1 FBXO27 gene_id:126433|Hs108|chr19 (283 aa)
initn: 685 init1: 265 opt: 664 Z-score: 650.6 bits: 128.3 E(32554): 6.5e-30
Smith-Waterman score: 664; 41.8% identity (64.7% similar) in 275 aa overlap (32-294:16-278)
10 20 30 40 50 60
pF1KB6 DGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAA
:: . :: : :..:: ::: ::.
CCDS12 MGASVSRGRAARVPAPEPEPEE-----ALDLSQLPPELLLVVLSH
10 20 30 40
70 80 90 100 110
pF1KB6 LPAAELVQACRLVCLRWKELVDGAPLWLLKCQQE-GLVPEGGVEEERDHWQQFY------
.: :. :: :: :. :::: :::: .. : . .. .. :. .
CCDS12 VPPRTLLGRCRQVCRGWRALVDGQALWLLILARDHGATGRALLHLARSCQSPARNARPCP
50 60 70 80 90 100
120 130 140 150 160
pF1KB6 ---FLSKRR--RNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHDESVKKYF
: ..: :::.:::::.: :. : :.:::::: ::: . . : . ... :
CCDS12 LGRFCARRPIGRNLIRNPCGQEGLRKWM-VQHGGDGWVVEE--NRTTVPGAPSQTC---F
110 120 130 140 150
170 180 190 200 210 220
pF1KB6 ASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHEN
..:: :: : ::.::. :: : ::::. . : :.::...: :.::.:.: :.::. ...
CCDS12 VTSFSWCCKKQVLDLEEEGLWPELLDSGRIEICVSDWWGARHDSGCMYRLLVQLLDANQT
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB6 VLAEFSSGQVAVPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTN
:: .::. .:: .... ....:.:.. ::::: ::: :::. .: : .::::::
CCDS12 VLDKFSAVPDPIPQWNNNAC-LHVTHVFSNIKMGVRFVSFEHRGQDTQFWAGHYGARVTN
220 230 240 250 260 270
290
pF1KB6 SSVWVEP
::: :
CCDS12 SSVIVRVRLS
280
>>CCDS12526.1 FBXO17 gene_id:115290|Hs108|chr19 (278 aa)
initn: 662 init1: 242 opt: 501 Z-score: 493.7 bits: 99.3 E(32554): 3.5e-21
Smith-Waterman score: 614; 39.2% identity (63.4% similar) in 268 aa overlap (47-294:18-273)
20 30 40 50 60 70
pF1KB6 SPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAALPAAELVQACRLVCL
:: :: ::..::. .: :: :: ::
CCDS12 MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCR
10 20 30 40
80 90 100 110 120
pF1KB6 RWKELVDGAPLWLLKCQQ----EG----LVPEGGVEEERDHWQQFYFLSKRR--------
:...::: .:::. . :: : . . ..:. ..: . . :
CCDS12 AWRDIVDGPTVWLLQLARDRSAEGRALYAVAQRCLPSNEDK-EEFPLCALARYCLRAPFG
50 60 70 80 90 100
130 140 150 160 170
pF1KB6 RNLLRNPCGEEDLEGWCDVEHGGDGWRVEE----LPGDSGVEFTHDESVKKYFASSFEWC
:::. : :::. ..:: .:::::.:: .:. .:: . . :..:::::
CCDS12 RNLIFNSCGEQGFRGW-EVEHGGNGWAIEKNLTPVPGAPS---------QTCFVTSFEWC
110 120 130 140 150
180 190 200 210 220 230
pF1KB6 RKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSS
: :..:: :: :.::::..: : : ::...: . ::.:.: :.::. .:. ...::.
CCDS12 SKRQLVDLVMEGVWQELLDSAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSA
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 GQVAVPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWVEP
. : : .. : ..::.::..: :.:.: ::. :.: : : .:: ::.::: :
CCDS12 SPDPVLQWTERGC-RQVSHVFTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRI
220 230 240 250 260 270
CCDS12 RLS
>>CCDS131.1 FBXO44 gene_id:93611|Hs108|chr1 (224 aa)
initn: 364 init1: 190 opt: 367 Z-score: 365.9 bits: 75.3 E(32554): 4.6e-14
Smith-Waterman score: 367; 40.5% identity (66.2% similar) in 148 aa overlap (43-188:2-147)
20 30 40 50 60 70
pF1KB6 PEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAALPAAELVQACR
:.. ..:::: .::.... .:: .:. ::
CCDS13 MAVGNINELPENILLELFTHVPARQLLLNCR
10 20 30
80 90 100 110 120 130
pF1KB6 LVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRRRNLLRNPCGEED
::: :..:.: . :: :: .::.. : . : :. :::: . .::::.:::.::
CCDS13 LVCSLWRDLIDLVTLWKRKCLREGFITEDWDQPVAD-WKIFYFLRSLHRNLLHNPCAEEG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 LEGWC-DVEHGGDGWRVEELPGDSGVEFTHDE-SVKKYFASSFEWCRKAQVIDLQAEGYW
.: : :: .::: :.::.: :. :: .:. . . . :.: :. .: :
CCDS13 FEFWSLDV-NGGDEWKVEDLSRDQRKEFPNDQVRSQARLRVQVPAVRSAPVVRARASGDL
100 110 120 130 140
200 210 220 230 240 250
pF1KB6 EELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVAVPQDSDGGGW
CCDS13 PARPGDHPAEERCQVEGGLPHILQLPARRPLHLVSARRRGHSLLGRLVRPEGHQQQHHHR
150 160 170 180 190 200
>>CCDS12529.1 NCCRP1 gene_id:342897|Hs108|chr19 (275 aa)
initn: 365 init1: 287 opt: 366 Z-score: 363.7 bits: 75.2 E(32554): 6.2e-14
Smith-Waterman score: 375; 32.8% identity (53.0% similar) in 302 aa overlap (1-295:14-272)
10 20 30 40
pF1KB6 MDGDGDPESVGQ--PEEASPEEQPEEASAEEERPEDQQEEEAAAAAA
:..:: : :. . : :: : : . . ::
CCDS12 MEEVREGHALGGGMEADG-PASLQELPPSPRSPSPPPSPP------PLPSPPSLPSPAAP
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 YLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGGVE-
::::: : :. ..: .:. .: .:: ::.:
CCDS12 EAPELPEP-------AQPSE--AHARQLLLEEW------GPL------------SGGLEL
60 70 80
110 120 130 140 150 160
pF1KB6 EERDHWQQFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHDES
.: :. . . :::::.: . : .. . . : : : :. . . :.
CCDS12 PQRLTWKLLLLRRPLYRNLLRSP-NPEGINIYEPAPPTGPTQRPLETLGNFRGWYIRTEK
90 100 110 120 130 140
170 180 190 200 210 220
pF1KB6 VKKYFASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWY-SGRSDAGCLYELTVKL
... . : : : .:: ::: :::::: ::::.: ::. ..: :: :.::: : :
CCDS12 LQQ----NQSWTVKQQCVDLLAEGLWEELLDDEQPAITVMDWFEDSRLDA-CVYELHVWL
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB6 LS-EHENVLAEFSSGQVAVPQDSDG--GGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWK
:. ....:.:. .:: .. : : :...::.: :::::::..: : ... .
CCDS12 LAADRRTVIAQH---HVAPRTSGRGPPGRWVQVSHVFRHYGPGVRFIHFLHKAKNRMEPG
210 220 230 240 250
290
pF1KB6 GWFGARVTNSSVWVEP
: .:::.::: :.
CCDS12 GLRRTRVTDSSVSVQLRE
260 270
>>CCDS81261.1 FBXO44 gene_id:93611|Hs108|chr1 (256 aa)
initn: 365 init1: 191 opt: 363 Z-score: 361.2 bits: 74.6 E(32554): 8.4e-14
Smith-Waterman score: 363; 43.7% identity (70.6% similar) in 126 aa overlap (43-167:2-125)
20 30 40 50 60 70
pF1KB6 PEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAALPAAELVQACR
:.. ..:::: .::.... .:: .:. ::
CCDS81 MAVGNINELPENILLELFTHVPARQLLLNCR
10 20 30
80 90 100 110 120 130
pF1KB6 LVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRRRNLLRNPCGEED
::: :..:.: . :: :: .::.. : . : :. :::: . .::::.:::.::
CCDS81 LVCSLWRDLIDLVTLWKRKCLREGFITEDWDQPVAD-WKIFYFLRSLHRNLLHNPCAEEG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 LEGWC-DVEHGGDGWRVEELPGDSGVEFTHDESVKKYFASSFEWCRKAQVIDLQAEGYWE
.: : :: .::: :.::.: :. :: .:. . .
CCDS81 FEFWSLDV-NGGDEWKVEDLSRDQRKEFPNDQHLPQVPGGGPQGRRVLGGADGYHTAGHR
100 110 120 130 140
200 210 220 230 240 250
pF1KB6 ELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVAVPQDSDGGGWM
CCDS81 GQGLVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPAR
150 160 170 180 190 200
296 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:38:15 2016 done: Fri Nov 4 20:38:16 2016
Total Scan time: 2.580 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]