FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6359, 254 aa 1>>>pF1KB6359 254 - 254 aa - 254 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8720+/-0.000974; mu= 11.4818+/- 0.059 mean_var=64.4051+/-12.694, 0's: 0 Z-trim(103.8): 33 B-trim: 0 in 0/50 Lambda= 0.159814 statistics sampled from 7596 (7607) to 7596 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.603), E-opt: 0.2 (0.234), width: 16 Scan time: 2.240 The best scores are: opt bits E(32554) CCDS45689.1 PSME3 gene_id:10197|Hs108|chr17 ( 254) 1620 382.3 1.8e-106 CCDS59290.1 PSME3 gene_id:10197|Hs108|chr17 ( 265) 1545 365.0 2.9e-101 CCDS82133.1 PSME3 gene_id:10197|Hs108|chr17 ( 193) 1239 294.4 3.8e-80 CCDS11442.1 PSME3 gene_id:10197|Hs108|chr17 ( 267) 879 211.4 5e-55 CCDS9612.1 PSME1 gene_id:5720|Hs108|chr14 ( 249) 679 165.3 3.5e-41 CCDS61415.1 PSME1 gene_id:5720|Hs108|chr14 ( 233) 600 147.1 1e-35 CCDS41930.1 PSME1 gene_id:5720|Hs108|chr14 ( 250) 600 147.1 1.1e-35 CCDS9614.1 PSME2 gene_id:5721|Hs108|chr14 ( 239) 426 107.0 1.2e-23 >>CCDS45689.1 PSME3 gene_id:10197|Hs108|chr17 (254 aa) initn: 1620 init1: 1620 opt: 1620 Z-score: 2025.1 bits: 382.3 E(32554): 1.8e-106 Smith-Waterman score: 1620; 100.0% identity (100.0% similar) in 254 aa overlap (1-254:1-254) 10 20 30 40 50 60 pF1KB6 MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIE 190 200 210 220 230 240 250 pF1KB6 KIKRPRSSNAETLY :::::::::::::: CCDS45 KIKRPRSSNAETLY 250 >>CCDS59290.1 PSME3 gene_id:10197|Hs108|chr17 (265 aa) initn: 1545 init1: 1545 opt: 1545 Z-score: 1931.4 bits: 365.0 E(32554): 2.9e-101 Smith-Waterman score: 1545; 100.0% identity (100.0% similar) in 241 aa overlap (14-254:25-265) 10 20 30 40 pF1KB6 MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPI :::::::::::::::::::::::::::::::::::: CCDS59 MEKWILKKIKYLQSGGLSASYYSYKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 LNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGML 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 KSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 KSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 SEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYV 190 200 210 220 230 240 230 240 250 pF1KB6 TLHDMILKNIEKIKRPRSSNAETLY ::::::::::::::::::::::::: CCDS59 TLHDMILKNIEKIKRPRSSNAETLY 250 260 >>CCDS82133.1 PSME3 gene_id:10197|Hs108|chr17 (193 aa) initn: 1239 init1: 1239 opt: 1239 Z-score: 1552.4 bits: 294.4 E(32554): 3.8e-80 Smith-Waterman score: 1239; 100.0% identity (100.0% similar) in 193 aa overlap (62-254:1-193) 40 50 60 70 80 90 pF1KB6 NFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDE :::::::::::::::::::::::::::::: CCDS82 MNLPVPDPILLTNSHDGLDGPTYKKRRLDE 10 20 30 100 110 120 130 140 150 pF1KB6 CEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 CEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGN 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 NFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 NFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDE 100 110 120 130 140 150 220 230 240 250 pF1KB6 KEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY ::::::::::::::::::::::::::::::::::::::::::: CCDS82 KEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY 160 170 180 190 >>CCDS11442.1 PSME3 gene_id:10197|Hs108|chr17 (267 aa) initn: 1606 init1: 879 opt: 879 Z-score: 1101.4 bits: 211.4 E(32554): 5e-55 Smith-Waterman score: 1584; 95.1% identity (95.1% similar) in 267 aa overlap (1-254:1-267) 10 20 30 40 50 60 pF1KB6 MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE 70 80 90 100 110 120 130 140 150 160 pF1KB6 KVKPEIRLLIEKCNT-------------VKMWVQLLIPRIEDGNNFGVSIQEETVAELRT ::::::::::::::: :::::::::::::::::::::::::::::::: CCDS11 KVKPEIRLLIEKCNTPSGKGPHICFDLQVKMWVQLLIPRIEDGNNFGVSIQEETVAELRT 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 VESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQ 190 200 210 220 230 240 230 240 250 pF1KB6 YVTLHDMILKNIEKIKRPRSSNAETLY ::::::::::::::::::::::::::: CCDS11 YVTLHDMILKNIEKIKRPRSSNAETLY 250 260 >>CCDS9612.1 PSME1 gene_id:5720|Hs108|chr14 (249 aa) initn: 672 init1: 473 opt: 679 Z-score: 852.7 bits: 165.3 E(32554): 3.5e-41 Smith-Waterman score: 679; 40.9% identity (74.2% similar) in 252 aa overlap (3-254:2-249) 10 20 30 40 50 60 pF1KB6 MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS ..:.:. :.. ::: ::: . ...:.:....::::. :::.::::: :: .:..... CCDS96 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKA 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE ...:::::. .... .:. :: ... . : : : .. :...: ... CCDS96 PLDIPVPDPVKEKEKEE--RKKQQEKEDKDEKKKGEDEDK--GPPCGPVNCNEKIVVLLQ 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 KVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQIS ..::::. .::. : : :.:: ::::::::::::..::.. . ..... .. ::: CCDS96 RLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQIS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 RYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIE .:. :. :.: :: ::: :::. : :.:: :: ..::.. :.:: :..:.:.::::.: CCDS96 KYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFE 180 190 200 210 220 230 250 pF1KB6 KIKRPRSSNAETLY :.:.::. . .: CCDS96 KLKKPRGETKGMIY 240 >>CCDS61415.1 PSME1 gene_id:5720|Hs108|chr14 (233 aa) initn: 597 init1: 398 opt: 600 Z-score: 754.8 bits: 147.1 E(32554): 1e-35 Smith-Waterman score: 600; 40.5% identity (73.1% similar) in 227 aa overlap (3-229:2-224) 10 20 30 40 50 60 pF1KB6 MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS ..:.:. :.. ::: ::: . ...:.:....::::. :::.::::: :: .:..... CCDS61 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKA 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE ...:::::. .... .:. :: ... . : : : .. :...: ... CCDS61 PLDIPVPDPVKEKEKEE--RKKQQEKEDKDEKKKGEDEDKG--PPCGPVNCNEKIVVLLQ 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 KVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQIS ..::::. .::. : : :.:: ::::::::::::..::.. . ..... .. ::: CCDS61 RLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQIS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 RYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIE .:. :. :.: :: ::: :::. : :.:: :: ..::.. :.:: :: CCDS61 KYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYVRRLCYMTSS 180 190 200 210 220 230 250 pF1KB6 KIKRPRSSNAETLY >>CCDS41930.1 PSME1 gene_id:5720|Hs108|chr14 (250 aa) initn: 597 init1: 398 opt: 600 Z-score: 754.3 bits: 147.1 E(32554): 1.1e-35 Smith-Waterman score: 600; 40.5% identity (73.1% similar) in 227 aa overlap (3-229:2-224) 10 20 30 40 50 60 pF1KB6 MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS ..:.:. :.. ::: ::: . ...:.:....::::. :::.::::: :: .:..... CCDS41 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKA 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE ...:::::. .... .:. :: ... . : : : .. :...: ... CCDS41 PLDIPVPDPVKEKEKEE--RKKQQEKEDKDEKKKGEDEDKG--PPCGPVNCNEKIVVLLQ 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 KVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQIS ..::::. .::. : : :.:: ::::::::::::..::.. . ..... .. ::: CCDS41 RLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQIS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 RYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIE .:. :. :.: :: ::: :::. : :.:: :: ..::.. :.:: :: CCDS41 KYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYVRRQGQGRGGQR 180 190 200 210 220 230 250 pF1KB6 KIKRPRSSNAETLY CCDS41 QLSQATHSLTLQARG 240 250 >>CCDS9614.1 PSME2 gene_id:5721|Hs108|chr14 (239 aa) initn: 582 init1: 399 opt: 426 Z-score: 537.8 bits: 107.0 E(32554): 1.2e-23 Smith-Waterman score: 535; 33.6% identity (66.8% similar) in 250 aa overlap (5-254:7-239) 10 20 30 40 50 pF1KB6 MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQI .... :.. .:. ::. . .:::... :.:.:.. :...:.: ::. :::.. CCDS96 MAKPCGVRLSGEARKQVEVFRQNLFQEAEEFLYRFLPQKIIYLNQLLQEDSLNVADLTSL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 HSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDI .. ...:.::: . : .. .:... .: :.: .:...... CCDS96 RAPLDIPIPDP---PPKDDEMETDKQEKKEVHKC--------------GFLPGNEKVLSL 70 80 90 100 120 130 140 150 160 170 pF1KB6 IEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQ . ::::. : ::: : :.: :::.:::::.:::.:::... .. .:.... .. CCDS96 LALVKPEVWTLKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTT 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 ISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKN ::.:. :. :.: .: :: ::: : : :: : :: .. .:: :. :. .: .: CCDS96 ISKYFSERGDAVAKASKETHVMDYRALVHERDEAAYGELRAMVLDLRAFYAELYHIISSN 170 180 190 200 210 220 240 250 pF1KB6 IEKIKRPRSSNAETLY .::: :.. . ..: CCDS96 LEKIVNPKGEEKPSMY 230 254 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:35:07 2016 done: Fri Nov 4 18:35:08 2016 Total Scan time: 2.240 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]