FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6363, 267 aa 1>>>pF1KB6363 267 - 267 aa - 267 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9991+/-0.000398; mu= 16.9511+/- 0.024 mean_var=72.1350+/-14.665, 0's: 0 Z-trim(113.0): 94 B-trim: 917 in 1/50 Lambda= 0.151008 statistics sampled from 22030 (22128) to 22030 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.259), width: 16 Scan time: 5.910 The best scores are: opt bits E(85289) NP_002222 (OMIM: 176807,600623) CD82 antigen isofo ( 267) 1813 404.1 1.4e-112 XP_006718286 (OMIM: 176807,600623) PREDICTED: CD82 ( 267) 1813 404.1 1.4e-112 XP_011518369 (OMIM: 176807,600623) PREDICTED: CD82 ( 236) 1519 340.0 2.4e-93 NP_001020015 (OMIM: 176807,600623) CD82 antigen is ( 242) 1107 250.3 2.5e-66 NP_001765 (OMIM: 151523) leukocyte antigen CD37 is ( 281) 503 118.7 1.2e-26 XP_005259492 (OMIM: 151523) PREDICTED: leukocyte a ( 365) 503 118.8 1.4e-26 NP_005714 (OMIM: 613136) tetraspanin-5 [Homo sapie ( 268) 442 105.4 1.1e-22 NP_000551 (OMIM: 151525) leukocyte surface antigen ( 219) 403 96.8 3.5e-20 NP_001035122 (OMIM: 151525) leukocyte surface anti ( 219) 403 96.8 3.5e-20 NP_006666 (OMIM: 613137) tetraspanin-9 [Homo sapie ( 239) 392 94.5 2e-19 NP_001161792 (OMIM: 613137) tetraspanin-9 [Homo sa ( 239) 392 94.5 2e-19 NP_003262 (OMIM: 602644) tetraspanin-4 isoform a [ ( 238) 391 94.3 2.3e-19 NP_001020405 (OMIM: 602644) tetraspanin-4 isoform ( 238) 391 94.3 2.3e-19 NP_001020409 (OMIM: 602644) tetraspanin-4 isoform ( 238) 391 94.3 2.3e-19 NP_001020406 (OMIM: 602644) tetraspanin-4 isoform ( 238) 391 94.3 2.3e-19 XP_005253159 (OMIM: 602644) PREDICTED: tetraspanin ( 238) 391 94.3 2.3e-19 NP_001020407 (OMIM: 602644) tetraspanin-4 isoform ( 238) 391 94.3 2.3e-19 NP_001020408 (OMIM: 602644) tetraspanin-4 isoform ( 238) 391 94.3 2.3e-19 XP_006716023 (OMIM: 610120) PREDICTED: tetraspanin ( 282) 373 90.4 3.9e-18 NP_848657 (OMIM: 610120) tetraspanin-33 [Homo sapi ( 283) 369 89.5 7.2e-18 NP_001760 (OMIM: 143030) CD9 antigen isoform 1 [Ho ( 228) 351 85.5 9.3e-17 XP_016875402 (OMIM: 600769) PREDICTED: tetraspanin ( 237) 346 84.5 2e-16 XP_006719646 (OMIM: 600769) PREDICTED: tetraspanin ( 237) 346 84.5 2e-16 NP_004607 (OMIM: 600769) tetraspanin-8 [Homo sapie ( 237) 346 84.5 2e-16 NP_005718 (OMIM: 613170) tetraspanin-1 [Homo sapie ( 241) 344 84.0 2.8e-16 XP_011538762 (OMIM: 613170) PREDICTED: tetraspanin ( 258) 344 84.1 2.9e-16 NP_001034579 (OMIM: 179620,602243,609057) CD151 an ( 253) 339 83.0 6.1e-16 NP_004348 (OMIM: 179620,602243,609057) CD151 antig ( 253) 339 83.0 6.1e-16 NP_620598 (OMIM: 179620,602243,609057) CD151 antig ( 253) 339 83.0 6.1e-16 NP_620599 (OMIM: 179620,602243,609057) CD151 antig ( 253) 339 83.0 6.1e-16 XP_005253871 (OMIM: 143030) PREDICTED: CD9 antigen ( 249) 324 79.7 5.8e-15 NP_004347 (OMIM: 186845,613496) CD81 antigen isofo ( 236) 315 77.7 2.2e-14 XP_011518638 (OMIM: 602644) PREDICTED: tetraspanin ( 269) 310 76.7 5.1e-14 NP_001035120 (OMIM: 151523) leukocyte antigen CD37 ( 213) 305 75.5 9.1e-14 XP_016883002 (OMIM: 151523) PREDICTED: leukocyte a ( 213) 305 75.5 9.1e-14 XP_011525846 (OMIM: 151523) PREDICTED: leukocyte a ( 213) 305 75.5 9.1e-14 XP_011525844 (OMIM: 151523) PREDICTED: leukocyte a ( 297) 305 75.6 1.2e-13 XP_005259493 (OMIM: 151523) PREDICTED: leukocyte a ( 297) 305 75.6 1.2e-13 XP_011525845 (OMIM: 151523) PREDICTED: leukocyte a ( 297) 305 75.6 1.2e-13 NP_001307567 (OMIM: 151525) leukocyte surface anti ( 160) 299 74.1 1.8e-13 NP_005715 (OMIM: 613134) tetraspanin-3 isoform 1 [ ( 253) 297 73.8 3.5e-13 NP_001295245 (OMIM: 613133) tetraspanin-2 isoform ( 193) 294 73.1 4.5e-13 NP_005716 (OMIM: 613133) tetraspanin-2 isoform 1 [ ( 221) 294 73.1 4.9e-13 NP_036471 (OMIM: 613140) tetraspanin-15 [Homo sapi ( 294) 270 68.0 2.3e-11 XP_005262737 (OMIM: 613136) PREDICTED: tetraspanin ( 219) 255 64.6 1.8e-10 XP_011519215 (OMIM: 613137) PREDICTED: tetraspanin ( 175) 247 62.8 5e-10 XP_011519214 (OMIM: 613137) PREDICTED: tetraspanin ( 175) 247 62.8 5e-10 XP_016877346 (OMIM: 613134) PREDICTED: tetraspanin ( 214) 244 62.2 9.2e-10 XP_011518794 (OMIM: 186845,613496) PREDICTED: CD81 ( 229) 239 61.1 2.1e-09 XP_011518639 (OMIM: 602644) PREDICTED: tetraspanin ( 174) 233 59.7 4.1e-09 >>NP_002222 (OMIM: 176807,600623) CD82 antigen isoform 1 (267 aa) initn: 1813 init1: 1813 opt: 1813 Z-score: 2142.3 bits: 404.1 E(85289): 1.4e-112 Smith-Waterman score: 1813; 99.6% identity (100.0% similar) in 267 aa overlap (1-267:1-267) 10 20 30 40 50 60 pF1KB6 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 EEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI 190 200 210 220 230 240 250 260 pF1KB6 VELLGMVLSICLCRHVHSEDYSKVPKY .:::::::::::::::::::::::::: NP_002 IELLGMVLSICLCRHVHSEDYSKVPKY 250 260 >>XP_006718286 (OMIM: 176807,600623) PREDICTED: CD82 ant (267 aa) initn: 1813 init1: 1813 opt: 1813 Z-score: 2142.3 bits: 404.1 E(85289): 1.4e-112 Smith-Waterman score: 1813; 99.6% identity (100.0% similar) in 267 aa overlap (1-267:1-267) 10 20 30 40 50 60 pF1KB6 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 EEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI 190 200 210 220 230 240 250 260 pF1KB6 VELLGMVLSICLCRHVHSEDYSKVPKY .:::::::::::::::::::::::::: XP_006 IELLGMVLSICLCRHVHSEDYSKVPKY 250 260 >>XP_011518369 (OMIM: 176807,600623) PREDICTED: CD82 ant (236 aa) initn: 1519 init1: 1519 opt: 1519 Z-score: 1796.9 bits: 340.0 E(85289): 2.4e-93 Smith-Waterman score: 1519; 99.1% identity (100.0% similar) in 222 aa overlap (46-267:15-236) 20 30 40 50 60 70 pF1KB6 FNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTMLMGFLGCI .::::::::::::::::::::::::::::: XP_011 MSELETACGKPMRHKTSSSSLRMGAYVFIGVGAVTMLMGFLGCI 10 20 30 40 80 90 100 110 120 130 pF1KB6 GAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYNSSREDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYNSSREDS 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB6 LQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFCEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFCEA 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB6 PGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIVELLGMVLSICLCRH :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_011 PGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRH 170 180 190 200 210 220 260 pF1KB6 VHSEDYSKVPKY :::::::::::: XP_011 VHSEDYSKVPKY 230 >>NP_001020015 (OMIM: 176807,600623) CD82 antigen isofor (242 aa) initn: 1105 init1: 1105 opt: 1107 Z-score: 1311.6 bits: 250.3 E(85289): 2.5e-66 Smith-Waterman score: 1597; 90.3% identity (90.6% similar) in 267 aa overlap (1-267:1-242) 10 20 30 40 50 60 pF1KB6 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI ::::::::::::::::::::::::::: :::::::: NP_001 GVGAVTMLMGFLGCIGAVNEVRCLLGL-------------------------LKQEMGGI 70 80 90 130 140 150 160 170 180 pF1KB6 VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 EEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI 160 170 180 190 200 210 250 260 pF1KB6 VELLGMVLSICLCRHVHSEDYSKVPKY .:::::::::::::::::::::::::: NP_001 IELLGMVLSICLCRHVHSEDYSKVPKY 220 230 240 >>NP_001765 (OMIM: 151523) leukocyte antigen CD37 isofor (281 aa) initn: 639 init1: 341 opt: 503 Z-score: 599.6 bits: 118.7 E(85289): 1.2e-26 Smith-Waterman score: 629; 37.0% identity (69.2% similar) in 276 aa overlap (4-267:6-280) 10 20 30 40 50 pF1KB6 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYV .:... :::::.:::.::.::..:. ::.::: ::.::.: . . :.. . : NP_001 MSAQESCLSLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQIWSKV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 FIGVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMG . : :: ...:::.::..:.::::::::..:::.. .:.: : :. . ..:.. . NP_001 LAISGIFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 GIVTELIRDYNSSREDSL-QDAWDYVQAQVKCCGWVSFYNWTDNAELM-NRPEV-TYPCS .: . :. :... :.. ...::::: :..:::: .: . : : :. ::: NP_001 DVVEKTIQKYGTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCS 130 140 150 160 170 180 180 190 200 210 220 pF1KB6 C-EVKGEEDNSL--SV------RKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQE : .... .:... .: : : . .. : . .:.::: . .: ::.. NP_001 CYNLSATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHN 190 200 210 220 230 240 230 240 250 260 pF1KB6 NLGIILGVGVGVAIVELLGMVLSICLCRHVHSEDYSKVPKY :: :.:. .::...:: :.::: :::.. .. :... .: NP_001 NLISIVGICLGVGLLELGFMTLSIFLCRNL-DHVYNRLARYR 250 260 270 280 >>XP_005259492 (OMIM: 151523) PREDICTED: leukocyte antig (365 aa) initn: 625 init1: 341 opt: 503 Z-score: 598.1 bits: 118.8 E(85289): 1.4e-26 Smith-Waterman score: 608; 36.9% identity (67.7% similar) in 263 aa overlap (4-254:6-268) 10 20 30 40 50 pF1KB6 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYV .:... :::::.:::.::.::..:. ::.::: ::.::.: . . :.. . : XP_005 MSAQESCLSLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQIWSKV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 FIGVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMG . : :: ...:::.::..:.::::::::..:::.. .:.: : :. . ..:.. . XP_005 LAISGIFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 GIVTELIRDYNSSREDSL-QDAWDYVQAQVKCCGWVSFYNWTDNAELM-NRPEV-TYPCS .: . :. :... :.. ...::::: :..:::: .: . : : :. ::: XP_005 DVVEKTIQKYGTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCS 130 140 150 160 170 180 180 190 200 210 220 pF1KB6 C-EVKGEEDNSLS--------VRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQE : .... .:... : : . .. : . .:.::: . .: ::.. XP_005 CYNLSATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHN 190 200 210 220 230 240 230 240 250 260 pF1KB6 NLGIILGVGVGVAIVELLGMVLSICLCRHVHSEDYSKVPKY :: :.:. .::...:. ::::. : : XP_005 NLISIVGICLGVGLLEMTVMVLSVQLQRRALRRKCEPHVPGAGDSSPGPSLIADGGGGHS 250 260 270 280 290 300 >>NP_005714 (OMIM: 613136) tetraspanin-5 [Homo sapiens] (268 aa) initn: 420 init1: 243 opt: 442 Z-score: 528.1 bits: 105.4 E(85289): 1.1e-22 Smith-Waterman score: 442; 31.0% identity (62.3% similar) in 268 aa overlap (3-259:12-260) 10 20 30 40 50 pF1KB6 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSS : :: :::.: ::.::..:: ..::.:.: .:. ::.. :: NP_005 MSGKHYKGPEVSCCI---KYFIFGFNVIFWFLGITFLGIGLWAWNEKG----VLSNISSI 10 20 30 40 50 60 70 80 90 100 pF1KB6 LRMGAY----VFIGVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFY .:.. .:. ::.: ...:: :::::. : :: .. .:: .:.. ..:::.: . NP_005 TDLGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAF 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 FNMGKLKQEMGGIVTELIRDYNSSRED-SLQDAWDYVQAQVKCCGWVSFYNWTDNAEL-- .:... .... :: : :.: .::. :..: .::: . .:. : . NP_005 VFKDWIKDQLYFFINNNIRAY---RDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNC 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 ----MNRPEVTYPCSCEVKGEEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKV .: . : :: .: .. .... :. . :. . .. .: .::. . NP_005 TDSNASRERCGVPFSCCTKDPAEDVINTQCGY-----DARQKPEVDQQIVIYTKGCVPQF 180 190 200 210 220 230 240 250 260 pF1KB6 QAWLQENLGIILGVGVGVAIVELLGMVLSICLCRHVHSEDYSKVPKY . :::.:: :. :. .:.:.....: ::: ... :. NP_005 EKWLQDNLTIVAGIFIGIALLQIFG----ICLAQNLVSDIEAVRASW 230 240 250 260 >>NP_000551 (OMIM: 151525) leukocyte surface antigen CD5 (219 aa) initn: 466 init1: 177 opt: 403 Z-score: 483.3 bits: 96.8 E(85289): 3.5e-20 Smith-Waterman score: 427; 32.9% identity (59.6% similar) in 255 aa overlap (1-254:1-209) 10 20 30 40 50 60 pF1KB6 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI :: . .:. :: ::.:::.:.: : :::::...: .. ..:: . :: .: ::. NP_000 MGMSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNN--FGVLFHNLPSLTLGN-VFV 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI ::.. :...::::.:...: .::: .: .::.::.:.:: . :.. ::.. .. NP_000 IVGSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG .:. :. :.: ..: . ::: .:. ..::: . .::.. : : :: NP_000 LTDSIHRYHS--DNSTKAAWDSIQSFLQCCGINGTSDWTSG------P----PASC---- 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 EEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI : : : :::. :.. :.. :. : . . : . NP_000 -------------------------PSDRKV--EGCYAKARLWFHSNFLYIGIITICVCV 170 180 190 250 260 pF1KB6 VELLGMVLSICL-CRHVHSEDYSKVPKY .:.::: ... : :. NP_000 IEVLGMSFALTLNCQIDKTSQTIGL 200 210 >>NP_001035122 (OMIM: 151525) leukocyte surface antigen (219 aa) initn: 466 init1: 177 opt: 403 Z-score: 483.3 bits: 96.8 E(85289): 3.5e-20 Smith-Waterman score: 427; 32.9% identity (59.6% similar) in 255 aa overlap (1-254:1-209) 10 20 30 40 50 60 pF1KB6 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI :: . .:. :: ::.:::.:.: : :::::...: .. ..:: . :: .: ::. NP_001 MGMSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNN--FGVLFHNLPSLTLGN-VFV 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI ::.. :...::::.:...: .::: .: .::.::.:.:: . :.. ::.. .. NP_001 IVGSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG .:. :. :.: ..: . ::: .:. ..::: . .::.. : : :: NP_001 LTDSIHRYHS--DNSTKAAWDSIQSFLQCCGINGTSDWTSG------P----PASC---- 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 EEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI : : : :::. :.. :.. :. : . . : . NP_001 -------------------------PSDRKV--EGCYAKARLWFHSNFLYIGIITICVCV 170 180 190 250 260 pF1KB6 VELLGMVLSICL-CRHVHSEDYSKVPKY .:.::: ... : :. NP_001 IEVLGMSFALTLNCQIDKTSQTIGL 200 210 >>NP_006666 (OMIM: 613137) tetraspanin-9 [Homo sapiens] (239 aa) initn: 485 init1: 240 opt: 392 Z-score: 469.9 bits: 94.5 E(85289): 2e-19 Smith-Waterman score: 497; 32.3% identity (65.4% similar) in 257 aa overlap (1-257:1-231) 10 20 30 40 50 60 pF1KB6 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI :. .:. ::..:::::::.. : .:: :.:. .....: .... : :: .: . : NP_006 MARGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNF-ATFSPSFPSLS-AANLVI 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI ..:...:. :::::.::..: .::: .: ::.::.:.. ::. : :.... NP_006 AIGTIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG . : . :.. . .:..::. .::...::: ... .: :: : : NP_006 LKEGLLLYHTENNVGLKNAWNIIQAEMRCCGVTDYTDW-------------YP----VLG 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 EEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI : :.. : : . .:. .. :... ::.:::. :...: .. ::. . : NP_006 E--NTVPDR---CCMEN--SQGCGRNATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILI 170 180 190 200 210 250 260 pF1KB6 VELLGMVLSICLCRHVHSEDYSKVPKY ...:::..:. : .:.: NP_006 MQILGMAFSMTLFQHIHRTGKKYDA 220 230 267 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:39:19 2016 done: Fri Nov 4 20:39:20 2016 Total Scan time: 5.910 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]