Result of FASTA (omim) for
pF1KB6368
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6368, 298 aa
1>>>pF1KB6368 298 - 298 aa - 298 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0749+/-0.000314; mu= 9.3408+/- 0.020
mean_var=140.3251+/-27.719, 0's: 0 Z-trim(121.6): 308 B-trim: 843 in 1/58
Lambda= 0.108270
statistics sampled from 38076 (38463) to 38076 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.451), width: 16
Scan time: 8.740
The best scores are: opt bits E(85289)
NP_054731 (OMIM: 610388) GTP-binding protein REM 1 ( 298) 1960 316.8 3.2e-86
XP_011527097 (OMIM: 610388) PREDICTED: GTP-binding ( 304) 1938 313.4 3.5e-85
XP_016883322 (OMIM: 610388) PREDICTED: GTP-binding ( 306) 1934 312.8 5.5e-85
XP_005260461 (OMIM: 610388) PREDICTED: GTP-binding ( 306) 1934 312.8 5.5e-85
NP_859053 (OMIM: 600164) GTP-binding protein GEM [ ( 296) 881 148.3 1.7e-35
NP_005252 (OMIM: 600164) GTP-binding protein GEM [ ( 296) 881 148.3 1.7e-35
NP_004156 (OMIM: 179503) GTP-binding protein RAD [ ( 308) 878 147.8 2.5e-35
NP_001122322 (OMIM: 179503) GTP-binding protein RA ( 308) 878 147.8 2.5e-35
NP_775798 (OMIM: 616955) GTP-binding protein REM 2 ( 340) 664 114.4 3.1e-25
XP_016876548 (OMIM: 616955) PREDICTED: GTP-binding ( 372) 664 114.5 3.3e-25
XP_005267440 (OMIM: 616955) PREDICTED: GTP-binding ( 341) 662 114.1 3.9e-25
XP_016876547 (OMIM: 616955) PREDICTED: GTP-binding ( 373) 662 114.1 4.1e-25
XP_016868804 (OMIM: 600164) PREDICTED: GTP-binding ( 208) 536 94.3 2.2e-19
NP_002921 (OMIM: 609592) GTP-binding protein Rit2 ( 217) 405 73.8 3.3e-13
XP_011534820 (OMIM: 616955) PREDICTED: GTP-binding ( 279) 401 73.3 6.2e-13
NP_008843 (OMIM: 609591,615355) GTP-binding protei ( 219) 373 68.8 1.1e-11
NP_001243750 (OMIM: 609591,615355) GTP-binding pro ( 236) 373 68.8 1.1e-11
XP_006715825 (OMIM: 179550) PREDICTED: ras-related ( 206) 364 67.4 2.7e-11
NP_005393 (OMIM: 179550) ras-related protein Ral-A ( 206) 364 67.4 2.7e-11
XP_011513768 (OMIM: 179550) PREDICTED: ras-related ( 206) 364 67.4 2.7e-11
NP_066361 (OMIM: 179540) ras-related protein Rap-2 ( 183) 358 66.4 4.7e-11
NP_002877 (OMIM: 179541) ras-related protein Rap-2 ( 183) 353 65.6 8.1e-11
XP_011509875 (OMIM: 179551) PREDICTED: ras-related ( 229) 339 63.5 4.4e-10
NP_036382 (OMIM: 600098) ras-related protein R-Ras ( 204) 337 63.2 5e-10
XP_005263786 (OMIM: 179551) PREDICTED: ras-related ( 206) 335 62.9 6.2e-10
XP_005263784 (OMIM: 179551) PREDICTED: ras-related ( 206) 335 62.9 6.2e-10
NP_002872 (OMIM: 179551) ras-related protein Ral-B ( 206) 335 62.9 6.2e-10
XP_016860111 (OMIM: 179551) PREDICTED: ras-related ( 206) 335 62.9 6.2e-10
XP_005263785 (OMIM: 179551) PREDICTED: ras-related ( 206) 335 62.9 6.2e-10
XP_016860110 (OMIM: 179551) PREDICTED: ras-related ( 228) 335 62.9 6.7e-10
XP_005263781 (OMIM: 179551) PREDICTED: ras-related ( 228) 335 62.9 6.7e-10
NP_006261 (OMIM: 165090) ras-related protein R-Ras ( 218) 323 61.0 2.4e-09
NP_001278825 (OMIM: 179520) ras-related protein Ra ( 184) 318 60.2 3.6e-09
XP_016857452 (OMIM: 179520) PREDICTED: ras-related ( 184) 318 60.2 3.6e-09
NP_001010935 (OMIM: 179520) ras-related protein Ra ( 184) 318 60.2 3.6e-09
NP_002875 (OMIM: 179520) ras-related protein Rap-1 ( 184) 318 60.2 3.6e-09
XP_016857451 (OMIM: 179520) PREDICTED: ras-related ( 184) 318 60.2 3.6e-09
XP_016857453 (OMIM: 179520) PREDICTED: ras-related ( 184) 318 60.2 3.6e-09
NP_056461 (OMIM: 179530) ras-related protein Rap-1 ( 184) 318 60.2 3.6e-09
NP_001010942 (OMIM: 179530) ras-related protein Ra ( 184) 318 60.2 3.6e-09
NP_116307 (OMIM: 612664) ras-related and estrogen- ( 199) 318 60.2 3.8e-09
NP_001243749 (OMIM: 609591,615355) GTP-binding pro ( 183) 315 59.7 5e-09
XP_006719132 (OMIM: 109800,114480,137215,163200,19 ( 189) 312 59.2 7e-09
NP_203524 (OMIM: 109800,114480,137215,163200,19007 ( 189) 312 59.2 7e-09
XP_011526015 (OMIM: 607862) PREDICTED: GTP-binding ( 232) 313 59.5 7.4e-09
XP_016874782 (OMIM: 109800,114480,137215,163200,19 ( 227) 312 59.3 8.1e-09
NP_060064 (OMIM: 607863) GTP-binding protein Di-Ra ( 199) 309 58.8 1e-08
NP_076429 (OMIM: 612404) ras-like protein family m ( 248) 310 59.0 1.1e-08
NP_005334 (OMIM: 109800,137550,162900,163200,18847 ( 189) 305 58.2 1.5e-08
NP_001123914 (OMIM: 109800,137550,162900,163200,18 ( 189) 305 58.2 1.5e-08
>>NP_054731 (OMIM: 610388) GTP-binding protein REM 1 [Ho (298 aa)
initn: 1960 init1: 1960 opt: 1960 Z-score: 1668.9 bits: 316.8 E(85289): 3.2e-86
Smith-Waterman score: 1960; 100.0% identity (100.0% similar) in 298 aa overlap (1-298:1-298)
10 20 30 40 50 60
pF1KB6 MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLGEDVYERT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 PAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLGEDVYERT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSFESASELRIQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSFESASELRIQLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQHNVAELFEGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQHNVAELFEGVV
190 200 210 220 230 240
250 260 270 280 290
pF1KB6 RQLRLRRRDSAAKEPPAPRRPASLAQRARRFLARLTARSARRRALKARSKSCHNLAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RQLRLRRRDSAAKEPPAPRRPASLAQRARRFLARLTARSARRRALKARSKSCHNLAVL
250 260 270 280 290
>>XP_011527097 (OMIM: 610388) PREDICTED: GTP-binding pro (304 aa)
initn: 1196 init1: 1196 opt: 1938 Z-score: 1650.2 bits: 313.4 E(85289): 3.5e-85
Smith-Waterman score: 1938; 98.0% identity (98.0% similar) in 304 aa overlap (1-298:1-304)
10 20 30 40 50 60
pF1KB6 MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPS
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 PAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLG------E
::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_011 PAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLGALPSVAE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 DVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSFESASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSFESASE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 LRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQHNVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQHNVAE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 LFEGVVRQLRLRRRDSAAKEPPAPRRPASLAQRARRFLARLTARSARRRALKARSKSCHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFEGVVRQLRLRRRDSAAKEPPAPRRPASLAQRARRFLARLTARSARRRALKARSKSCHN
250 260 270 280 290 300
pF1KB6 LAVL
::::
XP_011 LAVL
>>XP_016883322 (OMIM: 610388) PREDICTED: GTP-binding pro (306 aa)
initn: 1196 init1: 1196 opt: 1934 Z-score: 1646.8 bits: 312.8 E(85289): 5.5e-85
Smith-Waterman score: 1934; 97.4% identity (97.4% similar) in 306 aa overlap (1-298:1-306)
10 20 30 40 50 60
pF1KB6 MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPS
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 PAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLG-------
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLGDPALPSV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 -EDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSFESA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSFESA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 SELRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQHNV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 AELFEGVVRQLRLRRRDSAAKEPPAPRRPASLAQRARRFLARLTARSARRRALKARSKSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AELFEGVVRQLRLRRRDSAAKEPPAPRRPASLAQRARRFLARLTARSARRRALKARSKSC
250 260 270 280 290 300
pF1KB6 HNLAVL
::::::
XP_016 HNLAVL
>>XP_005260461 (OMIM: 610388) PREDICTED: GTP-binding pro (306 aa)
initn: 1196 init1: 1196 opt: 1934 Z-score: 1646.8 bits: 312.8 E(85289): 5.5e-85
Smith-Waterman score: 1934; 97.4% identity (97.4% similar) in 306 aa overlap (1-298:1-306)
10 20 30 40 50 60
pF1KB6 MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPS
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 PAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLG-------
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLGDPALPSV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 -EDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSFESA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSFESA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 SELRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQHNV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 AELFEGVVRQLRLRRRDSAAKEPPAPRRPASLAQRARRFLARLTARSARRRALKARSKSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AELFEGVVRQLRLRRRDSAAKEPPAPRRPASLAQRARRFLARLTARSARRRALKARSKSC
250 260 270 280 290 300
pF1KB6 HNLAVL
::::::
XP_005 HNLAVL
>>NP_859053 (OMIM: 600164) GTP-binding protein GEM [Homo (296 aa)
initn: 748 init1: 540 opt: 881 Z-score: 758.1 bits: 148.3 E(85289): 1.7e-35
Smith-Waterman score: 894; 52.1% identity (76.2% similar) in 286 aa overlap (27-298:14-296)
10 20 30 40 50
pF1KB6 MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLS-TVPSTQSQHPRLGQSASLNPPTQKP
: :: . ..:. ...: . . ..
NP_859 MTLNNVTMRQGTVGMQPQQQRWSIPA-DGRHLMVQKEPHQYSHRNRH
10 20 30 40
60 70 80 90 100
pF1KB6 SPAPDD-----WSSESSDSEGSWEA---LYRVVLLGDPGVGKTSLASLFAGKQER-DLH-
: .:.: :::.:.:: : :. :::::.:. ::::..::..::: .. :
NP_859 SATPEDHCRRSWSSDSTDSVISSESGNTYYRVVLIGEQGVGKSTLANIFAGVHDSMDSDC
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB6 EQLGEDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSF
: ::::.::::: ::::..:....: :: .: .. : .. :.: :.::.:::::.::.::
NP_859 EVLGEDTYERTLMVDGESATIILLDMWE-NKGENEWLHDHCMQVGDAYLIVYSITDRASF
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 ESASELRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQ
:.::::::::::..:.. .::::::::.::.::::::: ::::::::::::::::::..:
NP_859 EKASELRIQLRRARQTEDIPIILVGNKSDLVRCREVSVSEGRACAVVFDCKFIETSAAVQ
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB6 HNVAELFEGVVRQLRLRRRDSAAKEP---PAPRRPASLAQRARRFLARLTARSARRRALK
::: :::::.:::.:::: :: :. .: :. ..:::: ....:.. . :.:
NP_859 HNVKELFEGIVRQVRLRR-DSKEKNERRLAYQKRKESMPRKARRFWGKIVAKNNKNMAFK
230 240 250 260 270 280
290
pF1KB6 ARSKSCHNLAVL
.:::::.:.::
NP_859 LKSKSCHDLSVL
290
>>NP_005252 (OMIM: 600164) GTP-binding protein GEM [Homo (296 aa)
initn: 748 init1: 540 opt: 881 Z-score: 758.1 bits: 148.3 E(85289): 1.7e-35
Smith-Waterman score: 894; 52.1% identity (76.2% similar) in 286 aa overlap (27-298:14-296)
10 20 30 40 50
pF1KB6 MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLS-TVPSTQSQHPRLGQSASLNPPTQKP
: :: . ..:. ...: . . ..
NP_005 MTLNNVTMRQGTVGMQPQQQRWSIPA-DGRHLMVQKEPHQYSHRNRH
10 20 30 40
60 70 80 90 100
pF1KB6 SPAPDD-----WSSESSDSEGSWEA---LYRVVLLGDPGVGKTSLASLFAGKQER-DLH-
: .:.: :::.:.:: : :. :::::.:. ::::..::..::: .. :
NP_005 SATPEDHCRRSWSSDSTDSVISSESGNTYYRVVLIGEQGVGKSTLANIFAGVHDSMDSDC
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB6 EQLGEDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVYSIADRGSF
: ::::.::::: ::::..:....: :: .: .. : .. :.: :.::.:::::.::.::
NP_005 EVLGEDTYERTLMVDGESATIILLDMWE-NKGENEWLHDHCMQVGDAYLIVYSITDRASF
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 ESASELRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKFIETSATLQ
:.::::::::::..:.. .::::::::.::.::::::: ::::::::::::::::::..:
NP_005 EKASELRIQLRRARQTEDIPIILVGNKSDLVRCREVSVSEGRACAVVFDCKFIETSAAVQ
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB6 HNVAELFEGVVRQLRLRRRDSAAKEP---PAPRRPASLAQRARRFLARLTARSARRRALK
::: :::::.:::.:::: :: :. .: :. ..:::: ....:.. . :.:
NP_005 HNVKELFEGIVRQVRLRR-DSKEKNERRLAYQKRKESMPRKARRFWGKIVAKNNKNMAFK
230 240 250 260 270 280
290
pF1KB6 ARSKSCHNLAVL
.:::::.:.::
NP_005 LKSKSCHDLSVL
290
>>NP_004156 (OMIM: 179503) GTP-binding protein RAD [Homo (308 aa)
initn: 724 init1: 511 opt: 878 Z-score: 755.3 bits: 147.8 E(85289): 2.5e-35
Smith-Waterman score: 907; 51.4% identity (75.5% similar) in 294 aa overlap (12-298:34-308)
10 20 30
pF1KB6 MTLNTEQEAKTPLHRRASTPLPLSPRGHQ----PGRLSTVP
:::::. .:.. : : :: :...
NP_004 NGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRS---MPVDERDLQAALTPGALTAAA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 S-TQSQHPRLGQSASLNPPTQKPSPAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSL
. : .: ::: : . :. :: .:::. :..:.:.::: :::::..:
NP_004 AGTGTQGPRLDW----------PEDSEDSLSSGGSDSD---ESVYKVLLLGAPGVGKSAL
70 80 90 100
100 110 120 130 140 150
pF1KB6 ASLFAGKQERDLHEQLGEDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSA
: .:.: .. : :. .:.:...::::...:.: : :: . : :. :.:
NP_004 ARIFGGVEDGPEAEAAGH-TYDRSIVVDGEEASLMVYDIWEQD--GGRWLPGHCMAMGDA
110 120 130 140 150 160
160 170 180 190 200 210
pF1KB6 YVIVYSIADRGSFESASELRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVV
::::::..:.::::.:::::.::::..:.: :::::::::.::.: :::::.::::::::
NP_004 YVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVV
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB6 FDCKFIETSATLQHNVAELFEGVVRQLRLRR--RDSAAKEPPAPRRPASLAQRARRFLAR
::::::::::.:.::: ::::::::.:::: ... :.. . :: ::...:.:::.:
NP_004 FDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGR
230 240 250 260 270 280
280 290
pF1KB6 LTARSARRRALKARSKSCHNLAVL
..::..:. :..:.:::::.:.::
NP_004 IVARNSRKMAFRAKSKSCHDLSVL
290 300
>>NP_001122322 (OMIM: 179503) GTP-binding protein RAD [H (308 aa)
initn: 724 init1: 511 opt: 878 Z-score: 755.3 bits: 147.8 E(85289): 2.5e-35
Smith-Waterman score: 907; 51.4% identity (75.5% similar) in 294 aa overlap (12-298:34-308)
10 20 30
pF1KB6 MTLNTEQEAKTPLHRRASTPLPLSPRGHQ----PGRLSTVP
:::::. .:.. : : :: :...
NP_001 NGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRS---MPVDERDLQAALTPGALTAAA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 S-TQSQHPRLGQSASLNPPTQKPSPAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSL
. : .: ::: : . :. :: .:::. :..:.:.::: :::::..:
NP_001 AGTGTQGPRLDW----------PEDSEDSLSSGGSDSD---ESVYKVLLLGAPGVGKSAL
70 80 90 100
100 110 120 130 140 150
pF1KB6 ASLFAGKQERDLHEQLGEDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSA
: .:.: .. : :. .:.:...::::...:.: : :: . : :. :.:
NP_001 ARIFGGVEDGPEAEAAGH-TYDRSIVVDGEEASLMVYDIWEQD--GGRWLPGHCMAMGDA
110 120 130 140 150 160
160 170 180 190 200 210
pF1KB6 YVIVYSIADRGSFESASELRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVV
::::::..:.::::.:::::.::::..:.: :::::::::.::.: :::::.::::::::
NP_001 YVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVV
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB6 FDCKFIETSATLQHNVAELFEGVVRQLRLRR--RDSAAKEPPAPRRPASLAQRARRFLAR
::::::::::.:.::: ::::::::.:::: ... :.. . :: ::...:.:::.:
NP_001 FDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGR
230 240 250 260 270 280
280 290
pF1KB6 LTARSARRRALKARSKSCHNLAVL
..::..:. :..:.:::::.:.::
NP_001 IVARNSRKMAFRAKSKSCHDLSVL
290 300
>>NP_775798 (OMIM: 616955) GTP-binding protein REM 2 [Ho (340 aa)
initn: 532 init1: 453 opt: 664 Z-score: 574.0 bits: 114.4 E(85289): 3.1e-25
Smith-Waterman score: 704; 42.6% identity (64.9% similar) in 336 aa overlap (1-298:9-340)
10 20 30 40 50
pF1KB6 MTLNTEQEAKTPL-HRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSAS
: ..:: : : :::: : .:.. . :. . .. : : ..
NP_775 MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEA-DATLLKKSEKLLAELDRSGLPSA
10 20 30 40 50
60 70 80
pF1KB6 LNPPTQKPS-PAP-----------D--DW-----SSESSDSEGSWEA-------LYRVVL
. : .. : :.: : :: :: :::: :: :: ...:.:
NP_775 PGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVML
60 70 80 90 100 110
90 100 110 120 130 140
pF1KB6 LGDPGVGKTSLASLFAGKQERDLHEQLG-EDVYERTLTVDGEDTTLVVVDTWEAEKLDKS
.:. ::::..::. :.: : . :: . ::.::: . :: :..:::: : :: . .
NP_775 VGESGVGKSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWE-QGDAGG
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB6 WSQESCLQGGSAYVIVYSIADRGSFESASELRIQLRRTHQADHVPIILVGNKADLARCRE
: .. ::: :.:..::.:..:: :: .. : ..:: . .:.::::::.:::: ::
NP_775 WLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSRE
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB6 VSVEEGRACAVVFDCKFIETSATLQHNVAELFEGVVRQLRLRR-RDSAA---KEPPAPRR
::.:::: : ...:: :::::.:.::. :::::.:::.:::: :. :. .: .:.
NP_775 VSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEG
240 250 260 270 280 290
270 280 290
pF1KB6 PA------SLAQRARRFLARLTARSARRRALKARSKSCHNLAVL
:: ::...:.:::: :. :.:. .: ::.:::.:.::
NP_775 PAPPARRESLTKKAKRFLANLVPRNAK--FFKQRSRSCHDLSVL
300 310 320 330 340
>>XP_016876548 (OMIM: 616955) PREDICTED: GTP-binding pro (372 aa)
initn: 532 init1: 453 opt: 664 Z-score: 573.5 bits: 114.5 E(85289): 3.3e-25
Smith-Waterman score: 696; 45.1% identity (69.4% similar) in 297 aa overlap (21-298:88-372)
10 20 30 40 50
pF1KB6 MTLNTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSA
:: .: : : : ...: ... : .:..
XP_016 FSLPSHFILEADATLLKKSEKLLAELDRSGLPSAP-G-APRRRGSMPVPYKHQLRRAQAV
60 70 80 90 100 110
60 70 80 90 100
pF1KB6 S-LNPPTQKPSPAPDDWSSESSDSEGSWEA-------LYRVVLLGDPGVGKTSLASLFAG
. :. : :. :: :::: :: :: ...:.:.:. ::::..::. :.:
XP_016 DELDWP-------PQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVGKSTLAGTFGG
120 130 140 150 160
110 120 130 140 150 160
pF1KB6 KQERDLHEQLG-EDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSAYVIVY
: . :: . ::.::: . :: :..:::: : :: . .: .. ::: :.:..::.
XP_016 LQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWE-QGDAGGWLRDHCLQTGDAFLIVF
170 180 190 200 210 220
170 180 190 200 210 220
pF1KB6 SIADRGSFESASELRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVVFDCKF
:..:: :: .. : ..:: . .:.::::::.:::: ::::.:::: : ...::
XP_016 SVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKH
230 240 250 260 270 280
230 240 250 260 270
pF1KB6 IETSATLQHNVAELFEGVVRQLRLRR-RDSAA---KEPPAPRRPA------SLAQRARRF
:::::.:.::. :::::.:::.:::: :. :. .: .:. :: ::...:.::
XP_016 IETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRESLTKKAKRF
290 300 310 320 330 340
280 290
pF1KB6 LARLTARSARRRALKARSKSCHNLAVL
:: :. :.:. .: ::.:::.:.::
XP_016 LANLVPRNAKF--FKQRSRSCHDLSVL
350 360 370
298 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:30:55 2016 done: Fri Nov 4 18:30:56 2016
Total Scan time: 8.740 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]