Result of FASTA (omim) for pF1KB6373
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6373, 270 aa
  1>>>pF1KB6373 270 - 270 aa - 270 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9683+/-0.000303; mu= 17.1972+/- 0.019
 mean_var=70.2067+/-14.038, 0's: 0 Z-trim(117.5): 172  B-trim: 170 in 1/50
 Lambda= 0.153068
 statistics sampled from 29300 (29495) to 29300 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.346), width:  16
 Scan time:  6.640

The best scores are:                                      opt bits E(85289)
NP_057330 (OMIM: 612832) 17-beta-hydroxysteroid de ( 270) 1776 400.8 1.4e-111
XP_005259026 (OMIM: 612832) PREDICTED: 17-beta-hyd ( 212) 1174 267.7 1.2e-71
XP_005259027 (OMIM: 612832) PREDICTED: 17-beta-hyd ( 140)  625 146.4 2.8e-35
NP_060911 (OMIM: 605843) peroxisomal trans-2-enoyl ( 303)  389 94.5 2.5e-19
NP_065715 (OMIM: 615839) peroxisomal 2,4-dienoyl-C ( 292)  384 93.4 5.1e-19
XP_016868636 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326)  355 87.0 4.7e-17
XP_011515182 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326)  355 87.0 4.7e-17
XP_016868637 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326)  355 87.0 4.7e-17
NP_001317504 (OMIM: 222745) 2,4-dienoyl-CoA reduct ( 326)  355 87.0 4.7e-17
NP_001350 (OMIM: 222745) 2,4-dienoyl-CoA reductase ( 335)  355 87.0 4.8e-17
NP_066284 (OMIM: 611596) dehydrogenase/reductase S ( 278)  337 83.0 6.6e-16
NP_005785 (OMIM: 615194) dehydrogenase/reductase S ( 280)  324 80.1 4.8e-15
XP_005267306 (OMIM: 615194) PREDICTED: dehydrogena ( 280)  324 80.1 4.8e-15
XP_006720064 (OMIM: 615194) PREDICTED: dehydrogena ( 280)  324 80.1 4.8e-15
NP_057370 (OMIM: 260800,608347) L-xylulose reducta ( 244)  320 79.2   8e-15
NP_878912 (OMIM: 615194) dehydrogenase/reductase S ( 300)  303 75.5 1.3e-13
NP_001182147 (OMIM: 260800,608347) L-xylulose redu ( 242)  293 73.2   5e-13
XP_005250865 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 243)  279 70.2 4.3e-12
NP_000851 (OMIM: 119900,259100,601688) 15-hydroxyp ( 266)  277 69.7 6.2e-12
NP_002144 (OMIM: 109685) estradiol 17-beta-dehydro ( 387)  275 69.4 1.1e-11
XP_011508777 (OMIM: 612131) PREDICTED: dehydrogena ( 319)  274 69.1 1.1e-11
NP_001135743 (OMIM: 612131) dehydrogenase/reductas ( 319)  274 69.1 1.1e-11
NP_954674 (OMIM: 612131) dehydrogenase/reductase S ( 319)  274 69.1 1.1e-11
NP_001135742 (OMIM: 612131) dehydrogenase/reductas ( 319)  274 69.1 1.1e-11
NP_001276692 (OMIM: 612131) dehydrogenase/reductas ( 379)  274 69.2 1.3e-11
NP_055049 (OMIM: 601417) estradiol 17-beta-dehydro ( 261)  272 68.6 1.3e-11
XP_016862499 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324)  265 67.2 4.5e-11
XP_016862498 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324)  265 67.2 4.5e-11
XP_016862500 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330)  265 67.2 4.6e-11
XP_016862501 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330)  265 67.2 4.6e-11
XP_016862497 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330)  265 67.2 4.6e-11
NP_976060 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343)  265 67.2 4.7e-11
NP_004042 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343)  265 67.2 4.7e-11
XP_005269409 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343)  265 67.2 4.7e-11
XP_016862496 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343)  265 67.2 4.7e-11
NP_976059 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343)  265 67.2 4.7e-11
XP_011511369 (OMIM: 603063) PREDICTED: D-beta-hydr ( 347)  265 67.2 4.8e-11
NP_001309209 (OMIM: 612833) dehydrogenase/reductas ( 289)  257 65.4 1.4e-10
NP_057113 (OMIM: 612833) dehydrogenase/reductase S ( 339)  257 65.4 1.6e-10
XP_016876857 (OMIM: 612833) PREDICTED: dehydrogena ( 404)  257 65.5 1.8e-10
XP_011534641 (OMIM: 615194) PREDICTED: dehydrogena ( 204)  249 63.5 3.7e-10
XP_011534640 (OMIM: 615194) PREDICTED: dehydrogena ( 204)  249 63.5 3.7e-10
NP_001032900 (OMIM: 300220,300256,300438) 3-hydrox ( 252)  243 62.2 1.1e-09
NP_001139288 (OMIM: 119900,259100,601688) 15-hydro ( 178)  233 59.9 3.8e-09
NP_932349 (OMIM: 615196) dehydrogenase/reductase S ( 232)  233 60.0 4.7e-09
XP_016862503 (OMIM: 603063) PREDICTED: D-beta-hydr ( 206)  231 59.5 5.8e-09
XP_005269412 (OMIM: 603063) PREDICTED: D-beta-hydr ( 206)  231 59.5 5.8e-09
XP_016862504 (OMIM: 603063) PREDICTED: D-beta-hydr ( 206)  231 59.5 5.8e-09
NP_835236 (OMIM: 612127) 17-beta-hydroxysteroid de ( 300)  228 59.0 1.2e-08
NP_683695 (OMIM: 609769) short-chain dehydrogenase ( 313)  228 59.0 1.3e-08


>>NP_057330 (OMIM: 612832) 17-beta-hydroxysteroid dehydr  (270 aa)
 initn: 1776 init1: 1776 opt: 1776  Z-score: 2124.2  bits: 400.8 E(85289): 1.4e-111
Smith-Waterman score: 1776; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270)

               10        20        30        40        50        60
pF1KB6 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG
              190       200       210       220       230       240

              250       260       270
pF1KB6 IELLVTGGAELGYGCKASRSTPVDAPDIPS
       ::::::::::::::::::::::::::::::
NP_057 IELLVTGGAELGYGCKASRSTPVDAPDIPS
              250       260       270

>>XP_005259026 (OMIM: 612832) PREDICTED: 17-beta-hydroxy  (212 aa)
 initn: 1172 init1: 1172 opt: 1174  Z-score: 1407.1  bits: 267.7 E(85289): 1.2e-71
Smith-Waterman score: 1174; 90.8% identity (91.7% similar) in 206 aa overlap (1-205:1-204)

               10        20        30        40        50        60
pF1KB6 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN
              130       140       150       160       170       180

               190       200       210       220       230         
pF1KB6 CISPGNIW-TPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCT
       :      : .::   :      :. :                                  
XP_005 C--HWAAWASPLRSGLRQCSWPPKPTSARALNCS                          
                190       200       210                            

>>XP_005259027 (OMIM: 612832) PREDICTED: 17-beta-hydroxy  (140 aa)
 initn: 662 init1: 625 opt: 625  Z-score: 754.4  bits: 146.4 E(85289): 2.8e-35
Smith-Waterman score: 625; 94.1% identity (95.1% similar) in 102 aa overlap (1-102:1-102)

               10        20        30        40        50        60
pF1KB6 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT
       ::::::::::::::::::::::::::::::::  ::   ::.                  
XP_005 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHPRPPLPAEESRECHQHLQPGGGNRPGPG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN
                                                                   
XP_005 SSLCGHQGGSNSHDQSFGPG                                        
              130       140                                        

>>NP_060911 (OMIM: 605843) peroxisomal trans-2-enoyl-CoA  (303 aa)
 initn: 312 init1: 142 opt: 389  Z-score: 468.1  bits: 94.5 E(85289): 2.5e-19
Smith-Waterman score: 389; 32.8% identity (63.3% similar) in 256 aa overlap (9-251:18-267)

                        10        20        30        40           
pF1KB6          MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD----ESGGR
                        :.:..::::. ::: .::. ... :. ::: ..     .:.. 
NP_060 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD
               10        20        30        40        50        60

        50             60        70        80        90        100 
pF1KB6 ALEQELPGA-----VFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAG-HHPPPQRPEE
        :. .:: .     . : :.. .:..:..::. :.  ::... .:::.: .   :   :.
NP_060 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP--AEH
               70        80        90       100       110          

             110       120        130       140       150       160
pF1KB6 TSAQGFRQLLELNLLGTYTLTKLALP-YLRKSQGNVINISSLVGAIGQAQAVPYVATKGA
        :..:.. .:: :: ::. . : .   ....  :...::   . : :   ::   :....
NP_060 ISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKA-GFPLAVHSGAARAG
      120       130       140       150       160        170       

              170       180       190       200       210          
pF1KB6 VTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMG
       :  .::.:::. .  :.:.::..:: :..    :  .   .   .. :: . . :  :.:
NP_060 VYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQ---SFFEGSFQKIPAKRIG
       180       190       200       210          220       230    

     220       230        240       250       260       270        
pF1KB6 QPAEVGAAAVFLASEA-NFCTGIELLVTGGAELGYGCKASRSTPVDAPDIPS        
        : ::.... :: : : .: ::  . : ::  :                           
NP_060 VPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMK
          240       250       260       270       280       290    

NP_060 ETFKEKAKL
          300   

>>NP_065715 (OMIM: 615839) peroxisomal 2,4-dienoyl-CoA r  (292 aa)
 initn: 318 init1: 152 opt: 384  Z-score: 462.4  bits: 93.4 E(85289): 5.1e-19
Smith-Waterman score: 384; 32.1% identity (61.9% similar) in 252 aa overlap (10-253:29-275)

                                  10        20        30        40 
pF1KB6                    MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDK
                                   ::. .:::: :::  :.. :.  : ..:: ..
NP_065 MAQPPPDVEGDDCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASR
               10        20        30        40        50        60

              50        60             70        80         90     
pF1KB6 DESGGRALEQELPGAVFILC-----DVTQEDDVKTLVSETIRRFGRLDCVVN-NAGHHPP
       .     .  ..: ::.   :     ::     : . :......:::.: ..:  ::.   
NP_065 SLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLC
               70        80        90       100       110       120

         100       110       120        130       140       150    
pF1KB6 PQRPEETSAQGFRQLLELNLLGTYTLTK-LALPYLRKSQGNVINISSLVGAIGQAQAVPY
       :      : ..:. .....  ::..... :   ..:   : ..::.. .:  :::  :  
NP_065 PAG--ALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHA
                130       140       150       160       170        

          160       170       180       190       200       210    
pF1KB6 VATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQP
        ..:.:: :::. ::.. .: ..::: ..:: :     : :  :   :.:..   . :.:
NP_065 GSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGT--EGLRRL-GGPQASLSTKVTASP
      180       190       200       210         220        230     

          220       230        240       250       260       270
pF1KB6 LGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAELGYGCKASRSTPVDAPDIPS
       : :.:. .:.. ....:::  :.. ::  :.. ::: : .                 
NP_065 LQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLTFPNGVKGLPDFASFSAKL
         240       250       260       270       280       290  

>>XP_016868636 (OMIM: 222745) PREDICTED: 2,4-dienoyl-CoA  (326 aa)
 initn: 312 init1: 123 opt: 355  Z-score: 427.1  bits: 87.0 E(85289): 4.7e-17
Smith-Waterman score: 355; 29.9% identity (61.7% similar) in 261 aa overlap (1-251:42-296)

                                             10        20        30
pF1KB6                               MATGTRYAGKVVVVTGGGRGIGAGIVRAFV
                                     :   . . :::. .:::: :.: :..  . 
XP_016 MGEFFSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLS
              20        30        40        50        60        70 

               40        50             60        70        80     
pF1KB6 NSGARVVICDKDESGGRALEQELPGAV-----FILCDVTQEDDVKTLVSETIRRFGRLDC
       . ::. :: ..  .  .:  ... . .      : ::: . : :.. ::: :.  :. . 
XP_016 SLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNI
              80        90       100       110       120       130 

          90        100       110       120        130        140  
pF1KB6 VVNNA-GHHPPPQRPEETSAQGFRQLLELNLLGTYTLT-KLALPYLRKSQGNV-INISSL
       :.::: :.   :   :. : .... . .. : ::  .: ...   .. ..: . ..:...
XP_016 VINNAAGNFISPT--ERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTI
             140         150       160       170       180         

            150       160       170       180       190       200  
pF1KB6 VGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDP
        .  :.. .:: ...:..: ::.:.:: . . ::.: : :.::    :.  . :    ::
XP_016 YAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPG----PIKTKGAFSRLDP
     190       200       210       220       230           240     

            210        220       230        240       250       260
pF1KB6 RATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAELGYGCKASRS
        .:... :... : ::.:   :..  :.:: :. :.. .:  .   :: :.         
XP_016 TGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDL
         250       260       270       280       290       300     

              270           
pF1KB6 TPVDAPDIPS           
                            
XP_016 RKVTKEQWDTIEELIRKTKGS
         310       320      

>>XP_011515182 (OMIM: 222745) PREDICTED: 2,4-dienoyl-CoA  (326 aa)
 initn: 312 init1: 123 opt: 355  Z-score: 427.1  bits: 87.0 E(85289): 4.7e-17
Smith-Waterman score: 355; 29.9% identity (61.7% similar) in 261 aa overlap (1-251:42-296)

                                             10        20        30
pF1KB6                               MATGTRYAGKVVVVTGGGRGIGAGIVRAFV
                                     :   . . :::. .:::: :.: :..  . 
XP_011 KEMFFSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLS
              20        30        40        50        60        70 

               40        50             60        70        80     
pF1KB6 NSGARVVICDKDESGGRALEQELPGAV-----FILCDVTQEDDVKTLVSETIRRFGRLDC
       . ::. :: ..  .  .:  ... . .      : ::: . : :.. ::: :.  :. . 
XP_011 SLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNI
              80        90       100       110       120       130 

          90        100       110       120        130        140  
pF1KB6 VVNNA-GHHPPPQRPEETSAQGFRQLLELNLLGTYTLT-KLALPYLRKSQGNV-INISSL
       :.::: :.   :   :. : .... . .. : ::  .: ...   .. ..: . ..:...
XP_011 VINNAAGNFISPT--ERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTI
             140         150       160       170       180         

            150       160       170       180       190       200  
pF1KB6 VGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDP
        .  :.. .:: ...:..: ::.:.:: . . ::.: : :.::    :.  . :    ::
XP_011 YAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPG----PIKTKGAFSRLDP
     190       200       210       220       230           240     

            210        220       230        240       250       260
pF1KB6 RATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAELGYGCKASRS
        .:... :... : ::.:   :..  :.:: :. :.. .:  .   :: :.         
XP_011 TGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDL
         250       260       270       280       290       300     

              270           
pF1KB6 TPVDAPDIPS           
                            
XP_011 RKVTKEQWDTIEELIRKTKGS
         310       320      

>>XP_016868637 (OMIM: 222745) PREDICTED: 2,4-dienoyl-CoA  (326 aa)
 initn: 312 init1: 123 opt: 355  Z-score: 427.1  bits: 87.0 E(85289): 4.7e-17
Smith-Waterman score: 355; 29.9% identity (61.7% similar) in 261 aa overlap (1-251:42-296)

                                             10        20        30
pF1KB6                               MATGTRYAGKVVVVTGGGRGIGAGIVRAFV
                                     :   . . :::. .:::: :.: :..  . 
XP_016 MGEFFSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLS
              20        30        40        50        60        70 

               40        50             60        70        80     
pF1KB6 NSGARVVICDKDESGGRALEQELPGAV-----FILCDVTQEDDVKTLVSETIRRFGRLDC
       . ::. :: ..  .  .:  ... . .      : ::: . : :.. ::: :.  :. . 
XP_016 SLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNI
              80        90       100       110       120       130 

          90        100       110       120        130        140  
pF1KB6 VVNNA-GHHPPPQRPEETSAQGFRQLLELNLLGTYTLT-KLALPYLRKSQGNV-INISSL
       :.::: :.   :   :. : .... . .. : ::  .: ...   .. ..: . ..:...
XP_016 VINNAAGNFISPT--ERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTI
             140         150       160       170       180         

            150       160       170       180       190       200  
pF1KB6 VGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDP
        .  :.. .:: ...:..: ::.:.:: . . ::.: : :.::    :.  . :    ::
XP_016 YAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPG----PIKTKGAFSRLDP
     190       200       210       220       230           240     

            210        220       230        240       250       260
pF1KB6 RATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAELGYGCKASRS
        .:... :... : ::.:   :..  :.:: :. :.. .:  .   :: :.         
XP_016 TGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDL
         250       260       270       280       290       300     

              270           
pF1KB6 TPVDAPDIPS           
                            
XP_016 RKVTKEQWDTIEELIRKTKGS
         310       320      

>>NP_001317504 (OMIM: 222745) 2,4-dienoyl-CoA reductase,  (326 aa)
 initn: 312 init1: 123 opt: 355  Z-score: 427.1  bits: 87.0 E(85289): 4.7e-17
Smith-Waterman score: 355; 29.9% identity (61.7% similar) in 261 aa overlap (1-251:42-296)

                                             10        20        30
pF1KB6                               MATGTRYAGKVVVVTGGGRGIGAGIVRAFV
                                     :   . . :::. .:::: :.: :..  . 
NP_001 MGEFFSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLS
              20        30        40        50        60        70 

               40        50             60        70        80     
pF1KB6 NSGARVVICDKDESGGRALEQELPGAV-----FILCDVTQEDDVKTLVSETIRRFGRLDC
       . ::. :: ..  .  .:  ... . .      : ::: . : :.. ::: :.  :. . 
NP_001 SLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNI
              80        90       100       110       120       130 

          90        100       110       120        130        140  
pF1KB6 VVNNA-GHHPPPQRPEETSAQGFRQLLELNLLGTYTLT-KLALPYLRKSQGNV-INISSL
       :.::: :.   :   :. : .... . .. : ::  .: ...   .. ..: . ..:...
NP_001 VINNAAGNFISPT--ERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTI
             140         150       160       170       180         

            150       160       170       180       190       200  
pF1KB6 VGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDP
        .  :.. .:: ...:..: ::.:.:: . . ::.: : :.::    :.  . :    ::
NP_001 YAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPG----PIKTKGAFSRLDP
     190       200       210       220       230           240     

            210        220       230        240       250       260
pF1KB6 RATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAELGYGCKASRS
        .:... :... : ::.:   :..  :.:: :. :.. .:  .   :: :.         
NP_001 TGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDL
         250       260       270       280       290       300     

              270           
pF1KB6 TPVDAPDIPS           
                            
NP_001 RKVTKEQWDTIEELIRKTKGS
         310       320      

>>NP_001350 (OMIM: 222745) 2,4-dienoyl-CoA reductase, mi  (335 aa)
 initn: 277 init1: 123 opt: 355  Z-score: 427.0  bits: 87.0 E(85289): 4.8e-17
Smith-Waterman score: 355; 29.9% identity (61.7% similar) in 261 aa overlap (1-251:51-305)

                                             10        20        30
pF1KB6                               MATGTRYAGKVVVVTGGGRGIGAGIVRAFV
                                     :   . . :::. .:::: :.: :..  . 
NP_001 PRRFFSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLS
               30        40        50        60        70        80

               40        50             60        70        80     
pF1KB6 NSGARVVICDKDESGGRALEQELPGAV-----FILCDVTQEDDVKTLVSETIRRFGRLDC
       . ::. :: ..  .  .:  ... . .      : ::: . : :.. ::: :.  :. . 
NP_001 SLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNI
               90       100       110       120       130       140

          90        100       110       120        130        140  
pF1KB6 VVNNA-GHHPPPQRPEETSAQGFRQLLELNLLGTYTLT-KLALPYLRKSQGNV-INISSL
       :.::: :.   :   :. : .... . .. : ::  .: ...   .. ..: . ..:...
NP_001 VINNAAGNFISPT--ERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTI
              150         160       170       180       190        

            150       160       170       180       190       200  
pF1KB6 VGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDP
        .  :.. .:: ...:..: ::.:.:: . . ::.: : :.::    :.  . :    ::
NP_001 YAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPG----PIKTKGAFSRLDP
      200       210       220       230       240           250    

            210        220       230        240       250       260
pF1KB6 RATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAELGYGCKASRS
        .:... :... : ::.:   :..  :.:: :. :.. .:  .   :: :.         
NP_001 TGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDL
          260       270       280       290       300       310    

              270           
pF1KB6 TPVDAPDIPS           
                            
NP_001 RKVTKEQWDTIEELIRKTKGS
          320       330     




270 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 18:28:22 2016 done: Fri Nov  4 18:28:23 2016
 Total Scan time:  6.640 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com