FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6378, 299 aa 1>>>pF1KB6378 299 - 299 aa - 299 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6044+/-0.000419; mu= 6.8422+/- 0.026 mean_var=247.9081+/-49.460, 0's: 0 Z-trim(118.5): 35 B-trim: 0 in 0/57 Lambda= 0.081457 statistics sampled from 31441 (31475) to 31441 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.369), width: 16 Scan time: 7.970 The best scores are: opt bits E(85289) NP_067068 (OMIM: 605603) myozenin-1 [Homo sapiens] ( 299) 2013 249.4 6.5e-66 NP_057683 (OMIM: 605602,613838) myozenin-2 [Homo s ( 264) 305 48.6 1.6e-05 XP_006714297 (OMIM: 605602,613838) PREDICTED: myoz ( 195) 225 39.0 0.0089 >>NP_067068 (OMIM: 605603) myozenin-1 [Homo sapiens] (299 aa) initn: 2013 init1: 2013 opt: 2013 Z-score: 1304.4 bits: 249.4 E(85289): 6.5e-66 Smith-Waterman score: 2013; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299) 10 20 30 40 50 60 pF1KB6 MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 KLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 SGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 FKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 FKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTF 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 QMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 QMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL 250 260 270 280 290 >>NP_057683 (OMIM: 605602,613838) myozenin-2 [Homo sapie (264 aa) initn: 524 init1: 271 opt: 305 Z-score: 220.2 bits: 48.6 E(85289): 1.6e-05 Smith-Waterman score: 470; 34.8% identity (57.5% similar) in 287 aa overlap (11-296:9-257) 10 20 30 40 50 60 pF1KB6 MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMF :.::.. . :.. .:..::::.:.:::.:::::: :.:::...: NP_057 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLF 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 KLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGG :.:: : .:. .:: . : ....: ... : : . . :: .:::: . NP_057 KMRQRRSDKYTFENF-QYQSRAQINH------SIAMQNGKV------DGSNLEGGSQQAP 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 SGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITV . : . . . : : .:: . :: : NP_057 LTPPNT--PDPRSPPNPDNIAPGYSGPLKEIPPEKFNTTA-------------------V 110 120 130 140 190 200 210 220 230 240 pF1KB6 FKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTF : : ::::.:.. ::. : :. .::::: :.::::.: :.::.::::. . : NP_057 PKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELPDYRSFNRVATPFGGFEKASRMVKF 150 160 170 180 190 200 250 260 270 280 290 pF1KB6 QMPKFDLGPLLSEPLVL-YNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL ..: :.: ::..: . . . ::.: :::::: :.: . :. ... : : : NP_057 KVPDFELL-LLTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTE---PTDDTTVPE 210 220 230 240 250 260 NP_057 SEDL >>XP_006714297 (OMIM: 605602,613838) PREDICTED: myozenin (195 aa) initn: 362 init1: 225 opt: 225 Z-score: 170.9 bits: 39.0 E(85289): 0.0089 Smith-Waterman score: 297; 32.9% identity (53.5% similar) in 213 aa overlap (11-223:9-187) 10 20 30 40 50 60 pF1KB6 MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMF :.::.. . :.. .:..::::.:.:::.:::::: :.:::...: XP_006 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLF 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 KLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGG :.:: : .:. .:: . : ....: . : :. . . :: .:::: . XP_006 KMRQRRSDKYTFENF-QYQSRAQINH------------SIAMQNGKVDGSNLEGGSQQAP 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 SGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITV . : . . . : : .:: . :: : XP_006 LTPPNT--PDPRSPPNPDNIAPGYSGPLKEIPPEKFNTTA-------------------V 110 120 130 140 190 200 210 220 230 240 pF1KB6 FKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTF : : ::::.:.. ::. : :. .::::: :.:::: XP_006 PKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELPDYRSFNRGSRLHWRK 150 160 170 180 190 250 260 270 280 290 pF1KB6 QMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL 299 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:49:44 2016 done: Fri Nov 4 22:49:45 2016 Total Scan time: 7.970 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]