FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6379, 228 aa 1>>>pF1KB6379 228 - 228 aa - 228 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9707+/-0.000464; mu= -3.2491+/- 0.029 mean_var=173.4281+/-34.557, 0's: 0 Z-trim(115.0): 7 B-trim: 91 in 1/53 Lambda= 0.097390 statistics sampled from 25144 (25150) to 25144 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.295), width: 16 Scan time: 6.000 The best scores are: opt bits E(85289) NP_001196 (OMIM: 603291) vesicle transport protein ( 228) 1417 211.0 1.4e-54 NP_053582 (OMIM: 603291) vesicle transport protein ( 271) 1030 156.6 3.7e-38 XP_011532941 (OMIM: 603291) PREDICTED: vesicle tra ( 234) 640 101.8 1e-21 XP_011532940 (OMIM: 603291) PREDICTED: vesicle tra ( 241) 640 101.8 1.1e-21 NP_053581 (OMIM: 603291) vesicle transport protein ( 194) 625 99.7 3.8e-21 NP_053583 (OMIM: 603291) vesicle transport protein ( 237) 625 99.7 4.5e-21 >>NP_001196 (OMIM: 603291) vesicle transport protein SEC (228 aa) initn: 1417 init1: 1417 opt: 1417 Z-score: 1101.0 bits: 211.0 E(85289): 1.4e-54 Smith-Waterman score: 1417; 100.0% identity (100.0% similar) in 228 aa overlap (1-228:1-228) 10 20 30 40 50 60 pF1KB6 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM 130 140 150 160 170 180 190 200 210 220 pF1KB6 SGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL 190 200 210 220 >>NP_053582 (OMIM: 603291) vesicle transport protein SEC (271 aa) initn: 1403 init1: 1030 opt: 1030 Z-score: 806.0 bits: 156.6 E(85289): 3.7e-38 Smith-Waterman score: 1247; 83.5% identity (83.5% similar) in 260 aa overlap (12-228:12-271) 10 20 30 40 50 pF1KB6 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ- :::::::::::::::::::::::::::::::::::::::::::::::: NP_053 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 10 20 30 40 50 60 60 70 pF1KB6 ------------------------------------------DLEQLAKEQDKESEKQLL :::::::::::::::::: NP_053 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 70 80 90 100 110 120 80 90 100 110 120 130 pF1KB6 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 130 140 150 160 170 180 140 150 160 170 180 190 pF1KB6 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 190 200 210 220 230 240 200 210 220 pF1KB6 ELTDKLLIFLALALFLATVLYIVKKRLFPFL ::::::::::::::::::::::::::::::: NP_053 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 250 260 270 >>XP_011532941 (OMIM: 603291) PREDICTED: vesicle transpo (234 aa) initn: 1013 init1: 640 opt: 640 Z-score: 510.8 bits: 101.8 E(85289): 1e-21 Smith-Waterman score: 857; 77.9% identity (77.9% similar) in 195 aa overlap (12-163:12-206) 10 20 30 40 50 pF1KB6 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ- :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 10 20 30 40 50 60 60 70 pF1KB6 ------------------------------------------DLEQLAKEQDKESEKQLL :::::::::::::::::: XP_011 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 70 80 90 100 110 120 80 90 100 110 120 130 pF1KB6 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 130 140 150 160 170 180 140 150 160 170 180 190 pF1KB6 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR :::::::::::::::::::::::::: XP_011 ITESLMGISRMMAQQVQQSEEAMQSLGNTYSIEKDKKTLAQDCHRNATAATLSL 190 200 210 220 230 >>XP_011532940 (OMIM: 603291) PREDICTED: vesicle transpo (241 aa) initn: 1013 init1: 640 opt: 640 Z-score: 510.6 bits: 101.8 E(85289): 1.1e-21 Smith-Waterman score: 857; 77.9% identity (77.9% similar) in 195 aa overlap (12-163:12-206) 10 20 30 40 50 pF1KB6 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ- :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 10 20 30 40 50 60 60 70 pF1KB6 ------------------------------------------DLEQLAKEQDKESEKQLL :::::::::::::::::: XP_011 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 70 80 90 100 110 120 80 90 100 110 120 130 pF1KB6 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 130 140 150 160 170 180 140 150 160 170 180 190 pF1KB6 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR :::::::::::::::::::::::::: XP_011 ITESLMGISRMMAQQVQQSEEAMQSLGNTYSIEKDKKTLAQDCHRNATAATHFFTNDPGC 190 200 210 220 230 240 >>NP_053581 (OMIM: 603291) vesicle transport protein SEC (194 aa) initn: 1182 init1: 623 opt: 625 Z-score: 500.7 bits: 99.7 E(85289): 3.8e-21 Smith-Waterman score: 1118; 85.1% identity (85.1% similar) in 228 aa overlap (1-228:1-194) 10 20 30 40 50 60 pF1KB6 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL ::::::::::::::::::::::::::::: NP_053 LEQLAKEQDKESEKQLLLQEVENHKKQML------------------------------- 70 80 130 140 150 160 170 180 pF1KB6 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 ---RKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM 90 100 110 120 130 140 190 200 210 220 pF1KB6 SGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL :::::::::::::::::::::::::::::::::::::::::::::::: NP_053 SGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL 150 160 170 180 190 >>NP_053583 (OMIM: 603291) vesicle transport protein SEC (237 aa) initn: 1168 init1: 623 opt: 625 Z-score: 499.3 bits: 99.7 E(85289): 4.5e-21 Smith-Waterman score: 1022; 71.6% identity (71.6% similar) in 271 aa overlap (1-228:1-237) 10 20 30 40 50 pF1KB6 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 10 20 30 40 50 60 60 70 pF1KB6 ------------------------------------------DLEQLAKEQDKESEKQLL :::::::::::::::::: NP_053 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 70 80 90 100 110 120 80 90 100 110 120 130 pF1KB6 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST :::::::::::: :::::::::::::: NP_053 LQEVENHKKQML----------------------------------RKTTKESLAQTSST 130 140 140 150 160 170 180 190 pF1KB6 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 150 160 170 180 190 200 200 210 220 pF1KB6 ELTDKLLIFLALALFLATVLYIVKKRLFPFL ::::::::::::::::::::::::::::::: NP_053 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 210 220 230 228 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:39:22 2016 done: Sat Nov 5 16:39:22 2016 Total Scan time: 6.000 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]