FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6380, 299 aa 1>>>pF1KB6380 299 - 299 aa - 299 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9108+/-0.000383; mu= -0.4141+/- 0.024 mean_var=230.7223+/-44.241, 0's: 0 Z-trim(120.4): 8 B-trim: 0 in 0/57 Lambda= 0.084436 statistics sampled from 35620 (35628) to 35620 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.418), width: 16 Scan time: 9.020 The best scores are: opt bits E(85289) NP_006315 (OMIM: 608108) craniofacial development ( 299) 1904 244.3 2.1e-64 XP_011521116 (OMIM: 608108) PREDICTED: craniofacia ( 223) 1381 180.5 2.6e-45 XP_011521117 (OMIM: 608108) PREDICTED: craniofacia ( 220) 1375 179.8 4.2e-45 >>NP_006315 (OMIM: 608108) craniofacial development prot (299 aa) initn: 1904 init1: 1904 opt: 1904 Z-score: 1277.1 bits: 244.3 E(85289): 2.1e-64 Smith-Waterman score: 1904; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299) 10 20 30 40 50 60 pF1KB6 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 EVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMST 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 LEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLSKMKP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLSKMKP 250 260 270 280 290 >>XP_011521116 (OMIM: 608108) PREDICTED: craniofacial de (223 aa) initn: 1447 init1: 1381 opt: 1381 Z-score: 934.5 bits: 180.5 E(85289): 2.6e-45 Smith-Waterman score: 1381; 99.1% identity (99.5% similar) in 220 aa overlap (1-220:1-220) 10 20 30 40 50 60 pF1KB6 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 EVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMST ::::::::::::::::::::::::::::::::::::: :. XP_011 EVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGKKKFDA 190 200 210 220 250 260 270 280 290 pF1KB6 LEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLSKMKP >>XP_011521117 (OMIM: 608108) PREDICTED: craniofacial de (220 aa) initn: 1375 init1: 1375 opt: 1375 Z-score: 930.7 bits: 179.8 E(85289): 4.2e-45 Smith-Waterman score: 1375; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217) 10 20 30 40 50 60 pF1KB6 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 EVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMST ::::::::::::::::::::::::::::::::::::: XP_011 EVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGCVI 190 200 210 220 250 260 270 280 290 pF1KB6 LEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLSKMKP 299 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:42:13 2016 done: Fri Nov 4 20:42:14 2016 Total Scan time: 9.020 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]