FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6382, 300 aa 1>>>pF1KB6382 300 - 300 aa - 300 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5557+/-0.000437; mu= 13.5088+/- 0.027 mean_var=63.6858+/-12.337, 0's: 0 Z-trim(109.2): 12 B-trim: 33 in 1/53 Lambda= 0.160714 statistics sampled from 17382 (17388) to 17382 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.568), E-opt: 0.2 (0.204), width: 16 Scan time: 6.860 The best scores are: opt bits E(85289) NP_005722 (OMIM: 604224) actin-related protein 2/3 ( 300) 1951 461.5 9.3e-130 NP_690601 (OMIM: 604224) actin-related protein 2/3 ( 300) 1951 461.5 9.3e-130 XP_016858602 (OMIM: 604224) PREDICTED: actin-relat ( 245) 1605 381.2 1.1e-105 XP_016858603 (OMIM: 604224) PREDICTED: actin-relat ( 186) 1229 294.0 1.5e-79 XP_011508773 (OMIM: 604224) PREDICTED: actin-relat ( 186) 1229 294.0 1.5e-79 XP_016858604 (OMIM: 604224) PREDICTED: actin-relat ( 186) 1229 294.0 1.5e-79 >>NP_005722 (OMIM: 604224) actin-related protein 2/3 com (300 aa) initn: 1951 init1: 1951 opt: 1951 Z-score: 2450.5 bits: 461.5 E(85289): 9.3e-130 Smith-Waterman score: 1951; 100.0% identity (100.0% similar) in 300 aa overlap (1-300:1-300) 10 20 30 40 50 60 pF1KB6 MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSIS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 FMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 INLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 INLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR 250 260 270 280 290 300 >>NP_690601 (OMIM: 604224) actin-related protein 2/3 com (300 aa) initn: 1951 init1: 1951 opt: 1951 Z-score: 2450.5 bits: 461.5 E(85289): 9.3e-130 Smith-Waterman score: 1951; 100.0% identity (100.0% similar) in 300 aa overlap (1-300:1-300) 10 20 30 40 50 60 pF1KB6 MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSIS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 LKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 FASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 FMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 FMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 INLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 INLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR 250 260 270 280 290 300 >>XP_016858602 (OMIM: 604224) PREDICTED: actin-related p (245 aa) initn: 1605 init1: 1605 opt: 1605 Z-score: 2018.4 bits: 381.2 E(85289): 1.1e-105 Smith-Waterman score: 1605; 100.0% identity (100.0% similar) in 245 aa overlap (56-300:1-245) 30 40 50 60 70 80 pF1KB6 NKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGADELLKRVYGSFLV :::::::::::::::::::::::::::::: XP_016 MVSISLKFYKELQAHGADELLKRVYGSFLV 10 20 30 90 100 110 120 130 140 pF1KB6 NPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIH 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 YRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREP 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 PLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTR 160 170 180 190 200 210 270 280 290 300 pF1KB6 MRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR ::::::::::::::::::::::::::::::::::: XP_016 MRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR 220 230 240 >>XP_016858603 (OMIM: 604224) PREDICTED: actin-related p (186 aa) initn: 1229 init1: 1229 opt: 1229 Z-score: 1549.1 bits: 294.0 E(85289): 1.5e-79 Smith-Waterman score: 1229; 100.0% identity (100.0% similar) in 186 aa overlap (115-300:1-186) 90 100 110 120 130 140 pF1KB6 VNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVI :::::::::::::::::::::::::::::: XP_016 MLKRNCFASVFEKYFQFQEEGKEGENRAVI 10 20 30 150 160 170 180 190 200 pF1KB6 HYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHRE 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB6 PPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHT 100 110 120 130 140 150 270 280 290 300 pF1KB6 RMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR :::::::::::::::::::::::::::::::::::: XP_016 RMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR 160 170 180 >>XP_011508773 (OMIM: 604224) PREDICTED: actin-related p (186 aa) initn: 1229 init1: 1229 opt: 1229 Z-score: 1549.1 bits: 294.0 E(85289): 1.5e-79 Smith-Waterman score: 1229; 100.0% identity (100.0% similar) in 186 aa overlap (115-300:1-186) 90 100 110 120 130 140 pF1KB6 VNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVI :::::::::::::::::::::::::::::: XP_011 MLKRNCFASVFEKYFQFQEEGKEGENRAVI 10 20 30 150 160 170 180 190 200 pF1KB6 HYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHRE 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB6 PPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHT 100 110 120 130 140 150 270 280 290 300 pF1KB6 RMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR :::::::::::::::::::::::::::::::::::: XP_011 RMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR 160 170 180 >>XP_016858604 (OMIM: 604224) PREDICTED: actin-related p (186 aa) initn: 1229 init1: 1229 opt: 1229 Z-score: 1549.1 bits: 294.0 E(85289): 1.5e-79 Smith-Waterman score: 1229; 100.0% identity (100.0% similar) in 186 aa overlap (115-300:1-186) 90 100 110 120 130 140 pF1KB6 VNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVI :::::::::::::::::::::::::::::: XP_016 MLKRNCFASVFEKYFQFQEEGKEGENRAVI 10 20 30 150 160 170 180 190 200 pF1KB6 HYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHRE 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB6 PPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHT 100 110 120 130 140 150 270 280 290 300 pF1KB6 RMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR :::::::::::::::::::::::::::::::::::: XP_016 RMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR 160 170 180 300 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:43:55 2016 done: Fri Nov 4 20:43:56 2016 Total Scan time: 6.860 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]