FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6384, 300 aa 1>>>pF1KB6384 300 - 300 aa - 300 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7804+/-0.000715; mu= 9.8283+/- 0.044 mean_var=103.6797+/-20.860, 0's: 0 Z-trim(112.1): 10 B-trim: 0 in 0/53 Lambda= 0.125958 statistics sampled from 12924 (12933) to 12924 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.397), width: 16 Scan time: 2.760 The best scores are: opt bits E(32554) CCDS32817.1 TPGS2 gene_id:25941|Hs108|chr18 ( 300) 2024 377.6 6.2e-105 CCDS82248.1 TPGS2 gene_id:25941|Hs108|chr18 ( 248) 1490 280.5 8.6e-76 CCDS62423.1 TPGS2 gene_id:25941|Hs108|chr18 ( 227) 1485 279.6 1.5e-75 CCDS74215.1 TPGS2 gene_id:25941|Hs108|chr18 ( 232) 1485 279.6 1.5e-75 CCDS62424.1 TPGS2 gene_id:25941|Hs108|chr18 ( 304) 1486 279.8 1.7e-75 CCDS62422.1 TPGS2 gene_id:25941|Hs108|chr18 ( 265) 1241 235.3 3.8e-62 CCDS62421.1 TPGS2 gene_id:25941|Hs108|chr18 ( 257) 1184 224.9 4.9e-59 CCDS74214.1 TPGS2 gene_id:25941|Hs108|chr18 ( 130) 842 162.6 1.4e-40 >>CCDS32817.1 TPGS2 gene_id:25941|Hs108|chr18 (300 aa) initn: 2024 init1: 2024 opt: 2024 Z-score: 1997.3 bits: 377.6 E(32554): 6.2e-105 Smith-Waterman score: 2024; 100.0% identity (100.0% similar) in 300 aa overlap (1-300:1-300) 10 20 30 40 50 60 pF1KB6 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK 250 260 270 280 290 300 >>CCDS82248.1 TPGS2 gene_id:25941|Hs108|chr18 (248 aa) initn: 1490 init1: 1490 opt: 1490 Z-score: 1474.2 bits: 280.5 E(32554): 8.6e-76 Smith-Waterman score: 1490; 97.3% identity (99.1% similar) in 225 aa overlap (1-225:1-225) 10 20 30 40 50 60 pF1KB6 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETD ::::::::::::::::::::::::::::::::::::::: .... CCDS82 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKALLGLFDGSSPPVDLNNPRGR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK CCDS82 TGIRSRRF >>CCDS62423.1 TPGS2 gene_id:25941|Hs108|chr18 (227 aa) initn: 1485 init1: 1485 opt: 1485 Z-score: 1469.8 bits: 279.6 E(32554): 1.5e-75 Smith-Waterman score: 1485; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:1-219) 10 20 30 40 50 60 pF1KB6 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETD ::::::::::::::::::::::::::::::::::::::: CCDS62 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKVREEHLPL 190 200 210 220 250 260 270 280 290 300 pF1KB6 SFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK >>CCDS74215.1 TPGS2 gene_id:25941|Hs108|chr18 (232 aa) initn: 1485 init1: 1485 opt: 1485 Z-score: 1469.7 bits: 279.6 E(32554): 1.5e-75 Smith-Waterman score: 1485; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:1-219) 10 20 30 40 50 60 pF1KB6 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETD ::::::::::::::::::::::::::::::::::::::: CCDS74 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKPKGSEGRSKRGCF 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 SFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK >>CCDS62424.1 TPGS2 gene_id:25941|Hs108|chr18 (304 aa) initn: 1485 init1: 1485 opt: 1486 Z-score: 1468.9 bits: 279.8 E(32554): 1.7e-75 Smith-Waterman score: 1486; 97.8% identity (99.1% similar) in 224 aa overlap (1-224:1-224) 10 20 30 40 50 60 pF1KB6 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETD ::::::::::::::::::::::::::::::::::::::: ... CCDS62 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKITYNIKMNRRKCVHWKLAVEP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK CCDS62 LQWELRSCVSAGMGTGHKQRVSSMKPRSCSVCSRRQSNSMGTTVSQSFLSYGKNVLFFTV 250 260 270 280 290 300 >>CCDS62422.1 TPGS2 gene_id:25941|Hs108|chr18 (265 aa) initn: 1241 init1: 1241 opt: 1241 Z-score: 1229.2 bits: 235.3 E(32554): 3.8e-62 Smith-Waterman score: 1729; 88.3% identity (88.3% similar) in 300 aa overlap (1-300:1-265) 10 20 30 40 50 60 pF1KB6 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD :::::::::::::::::::::::: : CCDS62 MPEDVKNFYLMTNGFHMTWSVKLD-----------------------------------D 70 80 130 140 150 160 170 180 pF1KB6 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB6 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETD 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB6 SFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 SFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK 210 220 230 240 250 260 >>CCDS62421.1 TPGS2 gene_id:25941|Hs108|chr18 (257 aa) initn: 1184 init1: 1184 opt: 1184 Z-score: 1173.4 bits: 224.9 E(32554): 4.9e-59 Smith-Waterman score: 1657; 85.7% identity (85.7% similar) in 300 aa overlap (1-300:1-257) 10 20 30 40 50 60 pF1KB6 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD :::::::::::::::::::::::: CCDS62 MPEDVKNFYLMTNGFHMTWSVKLD------------------------------------ 70 80 130 140 150 160 170 180 pF1KB6 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 -------ASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL 90 100 110 120 130 190 200 210 220 230 240 pF1KB6 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 YWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETD 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB6 SFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 SFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK 200 210 220 230 240 250 >>CCDS74214.1 TPGS2 gene_id:25941|Hs108|chr18 (130 aa) initn: 842 init1: 842 opt: 842 Z-score: 842.1 bits: 162.6 E(32554): 1.4e-40 Smith-Waterman score: 842; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KB6 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRAL ::::::: CCDS74 LEDDTHEDNL 130 300 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:44:31 2016 done: Fri Nov 4 20:44:32 2016 Total Scan time: 2.760 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]