FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6385, 273 aa 1>>>pF1KB6385 273 - 273 aa - 273 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3631+/-0.000824; mu= 14.2197+/- 0.049 mean_var=60.2127+/-12.075, 0's: 0 Z-trim(106.1): 35 B-trim: 0 in 0/51 Lambda= 0.165284 statistics sampled from 8762 (8797) to 8762 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.27), width: 16 Scan time: 2.070 The best scores are: opt bits E(32554) CCDS10853.1 PSMB10 gene_id:5699|Hs108|chr16 ( 273) 1764 429.0 1.8e-120 CCDS6855.1 PSMB7 gene_id:5695|Hs108|chr9 ( 277) 1086 267.3 8.4e-72 CCDS4759.1 PSMB9 gene_id:5698|Hs108|chr6 ( 219) 335 88.2 5.5e-18 CCDS11056.1 PSMB6 gene_id:5694|Hs108|chr17 ( 239) 328 86.5 1.9e-17 CCDS73944.1 PSMB6 gene_id:5694|Hs108|chr17 ( 213) 296 78.9 3.4e-15 CCDS4757.1 PSMB8 gene_id:5696|Hs108|chr6 ( 276) 288 77.0 1.6e-14 CCDS4756.1 PSMB8 gene_id:5696|Hs108|chr6 ( 272) 285 76.3 2.6e-14 CCDS9584.1 PSMB5 gene_id:5693|Hs108|chr14 ( 263) 280 75.1 5.8e-14 CCDS41923.1 PSMB11 gene_id:122706|Hs108|chr14 ( 300) 277 74.4 1.1e-13 >>CCDS10853.1 PSMB10 gene_id:5699|Hs108|chr16 (273 aa) initn: 1764 init1: 1764 opt: 1764 Z-score: 2276.4 bits: 429.0 E(32554): 1.8e-120 Smith-Waterman score: 1764; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273) 10 20 30 40 50 60 pF1KB6 MLKPALEPRGGFSFENCQRNASLERVLPGLKVPHARKTGTTIAGLVFQDGVILGADTRAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MLKPALEPRGGFSFENCQRNASLERVLPGLKVPHARKTGTTIAGLVFQDGVILGADTRAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATVTR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ILRQTLFRYQGHVGASLIVGGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ILRQTLFRYQGHVGASLIVGGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 FQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVITKTGAKLLRTLSSPTEPVKRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 FQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVITKTGAKLLRTLSSPTEPVKRSGR 190 200 210 220 230 240 250 260 270 pF1KB6 YHFVPGTTAVLTQTVKPLTLELVEETVQAMEVE ::::::::::::::::::::::::::::::::: CCDS10 YHFVPGTTAVLTQTVKPLTLELVEETVQAMEVE 250 260 270 >>CCDS6855.1 PSMB7 gene_id:5695|Hs108|chr9 (277 aa) initn: 1116 init1: 987 opt: 1086 Z-score: 1402.5 bits: 267.3 E(32554): 8.4e-72 Smith-Waterman score: 1086; 58.3% identity (86.5% similar) in 266 aa overlap (8-271:10-275) 10 20 30 40 50 pF1KB6 MLKPALEPRGGFSFENCQRNASLERVLP--GLKVPHARKTGTTIAGLVFQDGVILGAD : :::::.::.::: :: . : :.:..:::::::::.:..::..:::: CCDS68 MAAVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGAD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 TRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVA ::::. :::::.: :::::.:.:::::::.:::..:::....:..:::.::::: :::. CCDS68 TRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 TVTRILRQTLFRYQGHVGASLIVGGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALAV :..:.:.: ::::::..::.:..::::.:::.::...:::: ..::....:::. ::.:: CCDS68 TANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 LEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVITKTGAKLLRTLSSPTEPVK .::.:.:.: : :..:. ::..:::..:::::.:.: :::.:. .:: . :.. CCDS68 FEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGT 190 200 210 220 230 240 240 250 260 270 pF1KB6 RSGRYHFVPGTTAVLTQTVKPLTLELVEETVQAMEVE : :::. :::::::. . :: .:..:::::.:. CCDS68 RLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS 250 260 270 >>CCDS4759.1 PSMB9 gene_id:5698|Hs108|chr6 (219 aa) initn: 306 init1: 306 opt: 335 Z-score: 436.3 bits: 88.2 E(32554): 5.5e-18 Smith-Waterman score: 335; 30.5% identity (64.5% similar) in 197 aa overlap (28-221:7-202) 10 20 30 40 50 pF1KB6 MLKPALEPRGGFSFENCQRNASLERVLPGLKVPHARK--TGTTIAGLVFQDGVILGADTR : .:.: . ::::: .. :. ::..:.:.: CCDS47 MLRAGAPTGDLPRAGEVHTGTTIMAVEFDGGVVMGSDSR 10 20 30 60 70 80 90 100 110 pF1KB6 ATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATV .. .:... .:. . .::: .: ::::. .. :.: ..:::.. . : : .. CCDS47 VSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAAYQLELHGIELEEPPLVLAA 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB6 TRILRQTLFRYQGHVGASLIVGGVDLT-GPQLYGVHPHGSYSRLPFTALGSGQDAALAVL . ..:. ..:. ..: :.:.: : : :.::. : .: ::. :::. . . CCDS47 ANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGTLG-GMLTRQPFAIGGSGSTFIYGYV 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB6 EDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVITKTGAKLLRTLSSPTEPVKR . ..:.:. : . . ..:.. .. : .::: . .:: .: CCDS47 DAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTITAAGVDHRVILGNELPKFYD 160 170 180 190 200 210 240 250 260 270 pF1KB6 SGRYHFVPGTTAVLTQTVKPLTLELVEETVQAMEVE CCDS47 E >>CCDS11056.1 PSMB6 gene_id:5694|Hs108|chr17 (239 aa) initn: 286 init1: 245 opt: 328 Z-score: 426.7 bits: 86.5 E(32554): 1.9e-17 Smith-Waterman score: 328; 29.9% identity (65.8% similar) in 187 aa overlap (38-223:33-219) 10 20 30 40 50 60 pF1KB6 PRGGFSFENCQRNASLERVLPGLKVPHARKTGTTIAGLVFQDGVILGADTRATNDSVVAD ::::: .. :. ::.::::.:.:. : .:. CCDS11 ATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATVTRILRQTLF . .:. : .:.:: .: :::.. .. :. .. .:.. .. : : :.. .... . CCDS11 RVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RYQGHVGASLIVGGVD-LTGPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMT ::. . :..:..: : : :.:.: : . : :. :::.. . .. .. .:: CCDS11 RYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LEAAQGLLVEAVTAGILGDLGSGGNVDACVITKTGAKLLRTLSSPTEPVKRSGRYHFVPG : . ..:.. .. : .::: . .:...:.. CCDS11 KEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA 190 200 210 220 230 250 260 270 pF1KB6 TTAVLTQTVKPLTLELVEETVQAMEVE >>CCDS73944.1 PSMB6 gene_id:5694|Hs108|chr17 (213 aa) initn: 243 init1: 222 opt: 296 Z-score: 386.3 bits: 78.9 E(32554): 3.4e-15 Smith-Waterman score: 296; 32.2% identity (66.4% similar) in 152 aa overlap (38-188:33-184) 10 20 30 40 50 60 pF1KB6 PRGGFSFENCQRNASLERVLPGLKVPHARKTGTTIAGLVFQDGVILGADTRATNDSVVAD ::::: .. :. ::.::::.:.:. : .:. CCDS73 ATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATVTRILRQTLF . .:. : .:.:: .: :::.. .. :. .. .:.. .. : : :.. .... . CCDS73 RVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RYQGHVGASLIVGGVD-LTGPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMT ::. . :..:..: : : :.:.: : . : :. :::.. . .. .. .:: CCDS73 RYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LEAAQGLLVEAVTAGILGDLGSGGNVDACVITKTGAKLLRTLSSPTEPVKRSGRYHFVPG : CCDS73 KEECLQFTANAFFFYPQLSLWPWSGMAPVEE 190 200 210 >>CCDS4757.1 PSMB8 gene_id:5696|Hs108|chr6 (276 aa) initn: 269 init1: 162 opt: 288 Z-score: 374.2 bits: 77.0 E(32554): 1.6e-14 Smith-Waterman score: 288; 29.8% identity (58.2% similar) in 225 aa overlap (1-221:37-255) 10 20 pF1KB6 MLKPALE-PRGGFSFENCQR-NASLERVLP : .: : ::: : : ... :: . CCDS47 CGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGDGERNVQ 10 20 30 40 50 60 30 40 50 60 70 80 pF1KB6 GLKVPHARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVA ... : ::: .. :: ::: ..:.::. : .. .:. : : . .: : CCDS47 -IEMAH----GTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCA 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB6 ADAEMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASL--IVGGVDLTG :: .. :..:.. .:. : .:.. :......: . . .:.: .: :. .. : : : CCDS47 ADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRG-MGLSMGSMICGWDKKG 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB6 PQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDL : :: : ::. . . :::. : .:... ..::.. : : : .:.. . : CCDS47 PGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDS 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB6 GSGGNVDACVITKTGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEET ::: :. . . : CCDS47 YSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ 250 260 270 >>CCDS4756.1 PSMB8 gene_id:5696|Hs108|chr6 (272 aa) initn: 269 init1: 162 opt: 285 Z-score: 370.4 bits: 76.3 E(32554): 2.6e-14 Smith-Waterman score: 287; 29.3% identity (58.1% similar) in 222 aa overlap (4-221:42-251) 10 20 30 pF1KB6 MLKPALEPRGGFSFE--NCQRNASLERVLPGLK :.::: :. . .::...: CCDS47 TPSSWLTSSLLVEAAPLDDTTLPTPVSSGCPGLEPTEFFQSLGGDGERNVQIE------- 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 VPHARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADA . : ::: .. :: ::: ..:.::. : .. .:. : : . .: ::: CCDS47 MAH----GTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADC 70 80 90 100 110 120 100 110 120 130 140 pF1KB6 EMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASL--IVGGVDLTGPQL .. :..:.. .:. : .:.. :......: . . .:.: .: :. .. : : :: : CCDS47 QYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRG-MGLSMGSMICGWDKKGPGL 130 140 150 160 170 150 160 170 180 190 200 pF1KB6 YGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSG : : ::. . . :::. : .:... ..::.. : : : .:.. . : :: CCDS47 YYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSG 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB6 GNVDACVITKTGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEETVQA : :. . . : CCDS47 GVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ 240 250 260 270 >>CCDS9584.1 PSMB5 gene_id:5693|Hs108|chr14 (263 aa) initn: 267 init1: 172 opt: 280 Z-score: 364.2 bits: 75.1 E(32554): 5.8e-14 Smith-Waterman score: 280; 29.1% identity (59.7% similar) in 196 aa overlap (28-221:52-242) 10 20 30 40 50 pF1KB6 MLKPALEPRGGFSFENCQRNASLERVLPGLKVPHARKTGTTIAGLVFQDGVILGADT ::... : ::: .. :. :::..::. CCDS95 GGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLH----GTTTLAFKFRHGVIVAADS 30 40 50 60 70 60 70 80 90 100 110 pF1KB6 RATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVAT ::: . .:... .:. : : . :: ::: . :..: . ... : . .. ::. CCDS95 RATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAA 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB6 VTRILRQTLFRYQGHVGASL--IVGGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALA ....: . ...:.: .: :. .. : : :: :: : .:. ..:::. : . CCDS95 ASKLLANMVYQYKG-MGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYG 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB6 VLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVITKTGAKLLRTLSSPTEPV :.. .. .. .: : : .:. . : ::: :. . . : CCDS95 VMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHE 200 210 220 230 240 250 240 250 260 270 pF1KB6 KRSGRYHFVPGTTAVLTQTVKPLTLELVEETVQAMEVE CCDS95 KYSGSTP 260 >>CCDS41923.1 PSMB11 gene_id:122706|Hs108|chr14 (300 aa) initn: 264 init1: 151 opt: 277 Z-score: 359.4 bits: 74.4 E(32554): 1.1e-13 Smith-Waterman score: 277; 28.5% identity (58.8% similar) in 221 aa overlap (4-221:19-232) 10 20 30 40 pF1KB6 MLKPALEPRGGFSF-ENCQRNASLERVLPGLKVPHARKTGTTIAG : : ::.. ..:. .. :. . : .. : ::: . CCDS41 MALQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFLQ--IHGPRLAH----GTTTLA 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 LVFQDGVILGADTRATNDSVVA-DKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKME . :. ::: .::::.. : :: :: :. . .. .:..:: :.. ... CCDS41 FRFRHGVIAAADTRSSCGSYVACPASC-KVIPVHQHLLGTTSGTSADCATWYRVLQRELR 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 LHALSTGREPRVATVTRILRQTLFRYQG-HVGASLIVGGVDLTGPQLYGVHPHGSYSRLP :. : :. : ::.....: . .:.: . .. . : : .::.:. :. :. . CCDS41 LRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTRLQGD 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 FTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVITKTGA . ..:::. : .::. .. .:. . : .: ::. . : :::.:: . ..: CCDS41 IFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGW 180 190 200 210 220 230 230 240 250 260 270 pF1KB6 KLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEETVQAMEVE CCDS41 EHVSRSDACVLYVELQKLLEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRM 240 250 260 270 280 290 273 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:45:05 2016 done: Fri Nov 4 20:45:06 2016 Total Scan time: 2.070 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]