FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6390, 301 aa 1>>>pF1KB6390 301 - 301 aa - 301 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8307+/-0.00033; mu= 15.1128+/- 0.021 mean_var=110.6221+/-22.457, 0's: 0 Z-trim(118.1): 9 B-trim: 0 in 0/54 Lambda= 0.121942 statistics sampled from 30697 (30706) to 30697 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.36), width: 16 Scan time: 8.050 The best scores are: opt bits E(85289) NP_061968 (OMIM: 608188) cardiolipin synthase (CMP ( 301) 2026 366.7 3.2e-101 XP_011527565 (OMIM: 608188) PREDICTED: cardiolipin ( 193) 1319 242.1 6.4e-64 NP_001120930 (OMIM: 608188) cardiolipin synthase ( ( 202) 1280 235.3 7.7e-62 NP_001310490 (OMIM: 608188) cardiolipin synthase ( ( 190) 1207 222.4 5.4e-58 NP_001310492 (OMIM: 608188) cardiolipin synthase ( ( 190) 1207 222.4 5.4e-58 XP_005260795 (OMIM: 608188) PREDICTED: cardiolipin ( 190) 1207 222.4 5.4e-58 NP_001310493 (OMIM: 608188) cardiolipin synthase ( ( 190) 1207 222.4 5.4e-58 NP_001310491 (OMIM: 608188) cardiolipin synthase ( ( 190) 1207 222.4 5.4e-58 >>NP_061968 (OMIM: 608188) cardiolipin synthase (CMP-for (301 aa) initn: 2026 init1: 2026 opt: 2026 Z-score: 1938.2 bits: 366.7 E(85289): 3.2e-101 Smith-Waterman score: 2026; 100.0% identity (100.0% similar) in 301 aa overlap (1-301:1-301) 10 20 30 40 50 60 pF1KB6 MLALRVARGSWGALRGAAWAPGTRPSKRRACWALLPPVPCCLGCLAERWRLRPAALGLRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MLALRVARGSWGALRGAAWAPGTRPSKRRACWALLPPVPCCLGCLAERWRLRPAALGLRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PGIGQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 PGIGQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWANQRSALGSALDPLADKILISIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 APVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWANQRSALGSALDPLADKILISIL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YVSLTYADLIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 YVSLTYADLIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 ISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIK 250 260 270 280 290 300 pF1KB6 D : NP_061 D >>XP_011527565 (OMIM: 608188) PREDICTED: cardiolipin syn (193 aa) initn: 1319 init1: 1319 opt: 1319 Z-score: 1268.5 bits: 242.1 E(85289): 6.4e-64 Smith-Waterman score: 1319; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB6 MLALRVARGSWGALRGAAWAPGTRPSKRRACWALLPPVPCCLGCLAERWRLRPAALGLRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLALRVARGSWGALRGAAWAPGTRPSKRRACWALLPPVPCCLGCLAERWRLRPAALGLRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PGIGQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGIGQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWANQRSALGSALDPLADKILISIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWANQRSALGSALDPLADKILISIL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YVSLTYADLIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTF ::::::::::: XP_011 YVSLTYADLIPGA 190 >>NP_001120930 (OMIM: 608188) cardiolipin synthase (CMP- (202 aa) initn: 1280 init1: 1280 opt: 1280 Z-score: 1231.2 bits: 235.3 E(85289): 7.7e-62 Smith-Waterman score: 1280; 100.0% identity (100.0% similar) in 199 aa overlap (103-301:4-202) 80 90 100 110 120 130 pF1KB6 GKAAPRPAAGAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGLAPVLGYLIIEED :::::::::::::::::::::::::::::: NP_001 MPQYENPWTIPNMLSMTRIGLAPVLGYLIIEED 10 20 30 140 150 160 170 180 190 pF1KB6 FNIALGVFALAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNIALGVFALAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPV 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 PLTYMIISRDVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLTYMIISRDVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLIL 100 110 120 130 140 150 260 270 280 290 300 pF1KB6 VAASLAAPVFNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAASLAAPVFNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD 160 170 180 190 200 >>NP_001310490 (OMIM: 608188) cardiolipin synthase (CMP- (190 aa) initn: 1207 init1: 1207 opt: 1207 Z-score: 1162.1 bits: 222.4 E(85289): 5.4e-58 Smith-Waterman score: 1207; 100.0% identity (100.0% similar) in 190 aa overlap (112-301:1-190) 90 100 110 120 130 140 pF1KB6 GAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFA :::::::::::::::::::::::::::::: NP_001 MLSMTRIGLAPVLGYLIIEEDFNIALGVFA 10 20 30 150 160 170 180 190 200 pF1KB6 LAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISR 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB6 DVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPV 100 110 120 130 140 150 270 280 290 300 pF1KB6 FNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD :::::::::::::::::::::::::::::::::::::::: NP_001 FNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD 160 170 180 190 >>NP_001310492 (OMIM: 608188) cardiolipin synthase (CMP- (190 aa) initn: 1207 init1: 1207 opt: 1207 Z-score: 1162.1 bits: 222.4 E(85289): 5.4e-58 Smith-Waterman score: 1207; 100.0% identity (100.0% similar) in 190 aa overlap (112-301:1-190) 90 100 110 120 130 140 pF1KB6 GAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFA :::::::::::::::::::::::::::::: NP_001 MLSMTRIGLAPVLGYLIIEEDFNIALGVFA 10 20 30 150 160 170 180 190 200 pF1KB6 LAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISR 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB6 DVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPV 100 110 120 130 140 150 270 280 290 300 pF1KB6 FNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD :::::::::::::::::::::::::::::::::::::::: NP_001 FNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD 160 170 180 190 >>XP_005260795 (OMIM: 608188) PREDICTED: cardiolipin syn (190 aa) initn: 1207 init1: 1207 opt: 1207 Z-score: 1162.1 bits: 222.4 E(85289): 5.4e-58 Smith-Waterman score: 1207; 100.0% identity (100.0% similar) in 190 aa overlap (112-301:1-190) 90 100 110 120 130 140 pF1KB6 GAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFA :::::::::::::::::::::::::::::: XP_005 MLSMTRIGLAPVLGYLIIEEDFNIALGVFA 10 20 30 150 160 170 180 190 200 pF1KB6 LAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISR 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB6 DVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPV 100 110 120 130 140 150 270 280 290 300 pF1KB6 FNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD :::::::::::::::::::::::::::::::::::::::: XP_005 FNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD 160 170 180 190 >>NP_001310493 (OMIM: 608188) cardiolipin synthase (CMP- (190 aa) initn: 1207 init1: 1207 opt: 1207 Z-score: 1162.1 bits: 222.4 E(85289): 5.4e-58 Smith-Waterman score: 1207; 100.0% identity (100.0% similar) in 190 aa overlap (112-301:1-190) 90 100 110 120 130 140 pF1KB6 GAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFA :::::::::::::::::::::::::::::: NP_001 MLSMTRIGLAPVLGYLIIEEDFNIALGVFA 10 20 30 150 160 170 180 190 200 pF1KB6 LAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISR 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB6 DVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPV 100 110 120 130 140 150 270 280 290 300 pF1KB6 FNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD :::::::::::::::::::::::::::::::::::::::: NP_001 FNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD 160 170 180 190 >>NP_001310491 (OMIM: 608188) cardiolipin synthase (CMP- (190 aa) initn: 1207 init1: 1207 opt: 1207 Z-score: 1162.1 bits: 222.4 E(85289): 5.4e-58 Smith-Waterman score: 1207; 100.0% identity (100.0% similar) in 190 aa overlap (112-301:1-190) 90 100 110 120 130 140 pF1KB6 GAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFA :::::::::::::::::::::::::::::: NP_001 MLSMTRIGLAPVLGYLIIEEDFNIALGVFA 10 20 30 150 160 170 180 190 200 pF1KB6 LAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISR 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB6 DVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPV 100 110 120 130 140 150 270 280 290 300 pF1KB6 FNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD :::::::::::::::::::::::::::::::::::::::: NP_001 FNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD 160 170 180 190 301 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:50:18 2016 done: Fri Nov 4 22:50:19 2016 Total Scan time: 8.050 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]