FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6392, 303 aa 1>>>pF1KB6392 303 - 303 aa - 303 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5273+/-0.000904; mu= 16.5958+/- 0.055 mean_var=121.5543+/-24.249, 0's: 0 Z-trim(110.9): 40 B-trim: 46 in 1/50 Lambda= 0.116329 statistics sampled from 11898 (11932) to 11898 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.367), width: 16 Scan time: 2.490 The best scores are: opt bits E(32554) CCDS34345.1 RNF144B gene_id:255488|Hs108|chr6 ( 303) 2225 384.1 7.1e-107 CCDS1657.1 RNF144A gene_id:9781|Hs108|chr2 ( 292) 1227 216.6 1.8e-56 CCDS10244.1 ARIH1 gene_id:25820|Hs108|chr15 ( 557) 388 76.1 6.7e-14 CCDS2780.1 ARIH2 gene_id:10425|Hs108|chr3 ( 493) 379 74.5 1.8e-13 >>CCDS34345.1 RNF144B gene_id:255488|Hs108|chr6 (303 aa) initn: 2225 init1: 2225 opt: 2225 Z-score: 2032.2 bits: 384.1 E(32554): 7.1e-107 Smith-Waterman score: 2225; 100.0% identity (100.0% similar) in 303 aa overlap (1-303:1-303) 10 20 30 40 50 60 pF1KB6 MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 CPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 CPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRGKKKKHDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 RNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRGKKKKHDP 250 260 270 280 290 300 pF1KB6 STT ::: CCDS34 STT >>CCDS1657.1 RNF144A gene_id:9781|Hs108|chr2 (292 aa) initn: 1232 init1: 620 opt: 1227 Z-score: 1127.2 bits: 216.6 E(32554): 1.8e-56 Smith-Waterman score: 1227; 55.6% identity (77.3% similar) in 295 aa overlap (12-303:1-292) 10 20 30 40 50 pF1KB6 MGSAGRLHYLAMTAENPTPG-DLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQ ::. : ::: ::..::::: : ...:::. .::::::: :::: CCDS16 MTTTRYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQ 10 20 30 40 60 70 80 90 100 110 pF1KB6 YMQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRT :..: :.:: . :.::: .: ..: ::: :: :.: .. .: :..:.::::: .:: :: CCDS16 YVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRT 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 WCPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIV-LPTEH :::.. ::.:: . . : :.: .:...::: :: .:: .: ...::. :: : CCDS16 WCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGET 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 RALFGTDAE-APIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDK : : . . ::::.:: :.:::::.:::::::::::::.::::::..::.:..: :::: CCDS16 SAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDK 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 GPCRNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRGKKKK ::::::::::::::.:.:::::::..:.:.. ::.::.::::.: ..:: :: .: CCDS16 GPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCSKGDD-- 230 240 250 260 270 280 300 pF1KB6 HDPSTT :: : CCDS16 -DPLPT 290 >>CCDS10244.1 ARIH1 gene_id:25820|Hs108|chr15 (557 aa) initn: 328 init1: 159 opt: 388 Z-score: 363.0 bits: 76.1 E(32554): 6.7e-14 Smith-Waterman score: 388; 31.5% identity (55.0% similar) in 200 aa overlap (28-223:184-376) 10 20 30 40 50 pF1KB6 MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACL . :..: . . .: : :: :: : CCDS10 LEKLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCW 160 170 180 190 200 210 60 70 80 90 100 110 pF1KB6 KQYMQLAI-REGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQL-YQRLKFEREVHLD ..:. : .:: :. :.:: : ... . :. .. .: ::.: . :. . CCDS10 SEYLTTKIMEEGMGQTISCPAHGC--DILVDDNTVMRLITDSKVKLKYQHLITNSFVECN 220 230 240 250 260 270 120 130 140 150 160 170 pF1KB6 PYRTWCPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLP :::. ::. : : : ..:: .: .: .:: : . :: :.:. . . CCDS10 RLLKWCPAPDCHHVVKVQYPD-AKPV--RC-KCGRQFCFNCGENWHDPVKCKWLKKWIKK 280 290 300 310 320 180 190 200 210 220 230 pF1KB6 TEHRALFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKN--CKHTFCWYCLQNLDNDIFLR . . .. : :.:: :.: ::.. :: .:.:.: :: ::: :: CCDS10 CDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAW 330 340 350 360 370 380 240 250 260 270 280 290 pF1KB6 HYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRG CCDS10 YNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQ 390 400 410 420 430 440 >>CCDS2780.1 ARIH2 gene_id:10425|Hs108|chr3 (493 aa) initn: 329 init1: 217 opt: 379 Z-score: 355.4 bits: 74.5 E(32554): 1.8e-13 Smith-Waterman score: 379; 29.0% identity (54.3% similar) in 210 aa overlap (17-223:124-327) 10 20 30 40 pF1KB6 MGSAGRLHYLAMTAENPTPGDLAPA--PLITCKLCLCEQSLDKMTT :.:. .:. : : .:. ... . CCDS27 ILVNFHWQVSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLS 100 110 120 130 140 150 50 60 70 80 90 100 pF1KB6 LQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQF-QLY : :: :: .: .:. .. ...: : ..: . : : . :.: ... . : CCDS27 LA-CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDC--PLRTPEDFVFPLLPNEELREKY 160 170 180 190 200 210 110 120 130 140 150 160 pF1KB6 QRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAE .: :. :. :: ::: : : ..: . :.: :. :: :.. .:: CCDS27 RRYLFRDYVESHYQLQLCPGADCPMVIRV--QEP-RARRVQCNRCNEVFCFKCRQMYHAP 220 230 240 250 260 170 180 190 200 210 220 pF1KB6 VSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCL ..: . . . .. : :.:: : . ::.: :: .:.:..::: :::.:: CCDS27 TDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCL 270 280 290 300 310 320 230 240 250 260 270 280 pF1KB6 QNLDNDIFLRHYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCI CCDS27 GDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQ 330 340 350 360 370 380 303 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:50:52 2016 done: Fri Nov 4 22:50:53 2016 Total Scan time: 2.490 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]