FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6393, 276 aa 1>>>pF1KB6393 276 - 276 aa - 276 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0024+/-0.000291; mu= 11.7279+/- 0.018 mean_var=84.4881+/-17.935, 0's: 0 Z-trim(118.2): 188 B-trim: 1656 in 1/55 Lambda= 0.139533 statistics sampled from 30662 (30908) to 30662 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.362), width: 16 Scan time: 7.850 The best scores are: opt bits E(85289) NP_001039021 (OMIM: 601099) src-like-adapter isofo ( 276) 1870 385.8 4.7e-107 NP_001039022 (OMIM: 601099) src-like-adapter isofo ( 293) 1870 385.8 5e-107 NP_006739 (OMIM: 601099) src-like-adapter isoform ( 316) 1870 385.8 5.3e-107 NP_001269894 (OMIM: 601099) src-like-adapter isofo ( 168) 1120 234.7 8.8e-62 XP_016869228 (OMIM: 601099) PREDICTED: src-like-ad ( 168) 1120 234.7 8.8e-62 NP_001269893 (OMIM: 601099) src-like-adapter isofo ( 249) 803 171.0 2e-42 NP_115590 (OMIM: 606577) src-like-adapter 2 isofor ( 261) 630 136.2 6.3e-32 XP_016883587 (OMIM: 606577) PREDICTED: src-like-ad ( 288) 475 105.0 1.7e-22 NP_778252 (OMIM: 606577) src-like-adapter 2 isofor ( 210) 472 104.3 2e-22 XP_011539756 (OMIM: 153390,615758) PREDICTED: tyro ( 516) 390 88.0 3.9e-17 XP_011539755 (OMIM: 153390,615758) PREDICTED: tyro ( 516) 390 88.0 3.9e-17 NP_001317397 (OMIM: 153390,615758) tyrosine-protei ( 458) 387 87.4 5.3e-17 NP_001165602 (OMIM: 142370) tyrosine-protein kinas ( 504) 336 77.1 7.1e-14 NP_001165600 (OMIM: 142370) tyrosine-protein kinas ( 505) 336 77.1 7.1e-14 NP_001165604 (OMIM: 142370) tyrosine-protein kinas ( 505) 336 77.1 7.1e-14 NP_001165603 (OMIM: 142370) tyrosine-protein kinas ( 506) 336 77.1 7.1e-14 NP_001165601 (OMIM: 142370) tyrosine-protein kinas ( 525) 336 77.2 7.4e-14 NP_002101 (OMIM: 142370) tyrosine-protein kinase H ( 526) 336 77.2 7.4e-14 XP_011542131 (OMIM: 191305,613375) PREDICTED: tyro ( 344) 321 74.0 4.2e-13 XP_011542130 (OMIM: 191305,613375) PREDICTED: tyro ( 345) 321 74.0 4.2e-13 NP_001317394 (OMIM: 191305,613375) tyrosine-protei ( 434) 321 74.1 5.1e-13 XP_011542129 (OMIM: 191305,613375) PREDICTED: tyro ( 460) 321 74.1 5.3e-13 NP_001706 (OMIM: 191305,613375) tyrosine-protein k ( 505) 321 74.1 5.8e-13 XP_011542126 (OMIM: 191305,613375) PREDICTED: tyro ( 531) 321 74.1 6e-13 XP_011542127 (OMIM: 191305,613375) PREDICTED: tyro ( 531) 321 74.1 6e-13 NP_001036236 (OMIM: 153390,615758) tyrosine-protei ( 509) 317 73.3 1e-12 NP_005347 (OMIM: 153390,615758) tyrosine-protein k ( 509) 317 73.3 1e-12 NP_001104567 (OMIM: 165120) tyrosine-protein kinas ( 491) 316 73.1 1.1e-12 XP_016868905 (OMIM: 165120) PREDICTED: tyrosine-pr ( 491) 316 73.1 1.1e-12 XP_016868904 (OMIM: 165120) PREDICTED: tyrosine-pr ( 499) 316 73.1 1.2e-12 NP_002341 (OMIM: 165120) tyrosine-protein kinase L ( 512) 316 73.1 1.2e-12 XP_011515831 (OMIM: 165120) PREDICTED: tyrosine-pr ( 682) 316 73.2 1.5e-12 XP_005266937 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 313 72.5 1.8e-12 XP_011533955 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 313 72.5 1.8e-12 XP_011533957 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 313 72.5 1.8e-12 XP_005266939 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 313 72.5 1.8e-12 NP_002022 (OMIM: 606573) tyrosine-protein kinase F ( 505) 313 72.5 1.8e-12 XP_005266938 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 313 72.5 1.8e-12 XP_011533956 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 313 72.5 1.8e-12 XP_016866134 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 313 72.5 1.8e-12 XP_011533958 (OMIM: 606573) PREDICTED: tyrosine-pr ( 392) 307 71.2 3.3e-12 XP_011539315 (OMIM: 164940) PREDICTED: tyrosine-pr ( 352) 304 70.6 4.6e-12 XP_011539314 (OMIM: 164940) PREDICTED: tyrosine-pr ( 410) 304 70.7 5.2e-12 XP_016866144 (OMIM: 137025) PREDICTED: tyrosine-pr ( 311) 302 70.2 5.5e-12 NP_005239 (OMIM: 164940) tyrosine-protein kinase F ( 529) 304 70.7 6.4e-12 XP_006710515 (OMIM: 164940) PREDICTED: tyrosine-pr ( 529) 304 70.7 6.4e-12 NP_001036194 (OMIM: 164940) tyrosine-protein kinas ( 529) 304 70.7 6.4e-12 XP_011539312 (OMIM: 164940) PREDICTED: tyrosine-pr ( 529) 304 70.7 6.4e-12 NP_001036212 (OMIM: 164940) tyrosine-protein kinas ( 529) 304 70.7 6.4e-12 NP_002028 (OMIM: 137025) tyrosine-protein kinase F ( 537) 302 70.3 8.6e-12 >>NP_001039021 (OMIM: 601099) src-like-adapter isoform a (276 aa) initn: 1870 init1: 1870 opt: 1870 Z-score: 2042.9 bits: 385.8 E(85289): 4.7e-107 Smith-Waterman score: 1870; 100.0% identity (100.0% similar) in 276 aa overlap (1-276:1-276) 10 20 30 40 50 60 pF1KB6 MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT 190 200 210 220 230 240 250 260 270 pF1KB6 SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED :::::::::::::::::::::::::::::::::::: NP_001 SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED 250 260 270 >>NP_001039022 (OMIM: 601099) src-like-adapter isoform b (293 aa) initn: 1870 init1: 1870 opt: 1870 Z-score: 2042.5 bits: 385.8 E(85289): 5e-107 Smith-Waterman score: 1870; 100.0% identity (100.0% similar) in 276 aa overlap (1-276:18-293) 10 20 30 40 pF1KB6 MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIF ::::::::::::::::::::::::::::::::::::::::::: NP_001 MLHRLWASPAAPGKKKEMGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 RRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDT 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 KVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEV 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 ADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDES 190 200 210 220 230 240 230 240 250 260 270 pF1KB6 LFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED 250 260 270 280 290 >>NP_006739 (OMIM: 601099) src-like-adapter isoform c [H (316 aa) initn: 1870 init1: 1870 opt: 1870 Z-score: 2042.0 bits: 385.8 E(85289): 5.3e-107 Smith-Waterman score: 1870; 100.0% identity (100.0% similar) in 276 aa overlap (1-276:41-316) 10 20 30 pF1KB6 MGNSMKSTPAPAERPLPNPEGLDSDFLAVL :::::::::::::::::::::::::::::: NP_006 GGLRARLTFPVCLLYHRLWASPAAPGKKKEMGNSMKSTPAPAERPLPNPEGLDSDFLAVL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 SDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLG 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 RDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLPNNWYYISPRLTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLPNNWYYISPRLTF 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB6 QCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQED 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB6 PEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSS 260 270 280 290 300 310 pF1KB6 PPYFED :::::: NP_006 PPYFED >>NP_001269894 (OMIM: 601099) src-like-adapter isoform e (168 aa) initn: 1120 init1: 1120 opt: 1120 Z-score: 1230.2 bits: 234.7 E(85289): 8.8e-62 Smith-Waterman score: 1120; 100.0% identity (100.0% similar) in 168 aa overlap (109-276:1-168) 80 90 100 110 120 130 pF1KB6 RVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLP :::::::::::::::::::::::::::::: NP_001 MIRESETKKGFYSLSVRHRQVKHYRIFRLP 10 20 30 140 150 160 170 180 190 pF1KB6 NNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKT 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 VDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMY 100 110 120 130 140 150 260 270 pF1KB6 GGSKRKSSFFSSPPYFED :::::::::::::::::: NP_001 GGSKRKSSFFSSPPYFED 160 >>XP_016869228 (OMIM: 601099) PREDICTED: src-like-adapte (168 aa) initn: 1120 init1: 1120 opt: 1120 Z-score: 1230.2 bits: 234.7 E(85289): 8.8e-62 Smith-Waterman score: 1120; 100.0% identity (100.0% similar) in 168 aa overlap (109-276:1-168) 80 90 100 110 120 130 pF1KB6 RVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLP :::::::::::::::::::::::::::::: XP_016 MIRESETKKGFYSLSVRHRQVKHYRIFRLP 10 20 30 140 150 160 170 180 190 pF1KB6 NNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKT 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 VDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMY 100 110 120 130 140 150 260 270 pF1KB6 GGSKRKSSFFSSPPYFED :::::::::::::::::: XP_016 GGSKRKSSFFSSPPYFED 160 >>NP_001269893 (OMIM: 601099) src-like-adapter isoform d (249 aa) initn: 1541 init1: 803 opt: 803 Z-score: 882.7 bits: 171.0 E(85289): 2e-42 Smith-Waterman score: 1457; 84.1% identity (84.1% similar) in 276 aa overlap (1-276:18-249) 10 20 30 40 pF1KB6 MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIF ::::::::::::::::::::::::::::::::::::::::::: NP_001 MLHRLWASPAAPGKKKEMGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 RRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDT 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 KVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEV :::::::::::::: :: NP_001 KVGSFMIRESETKK--------------------------------------------EV 130 170 180 190 200 210 220 pF1KB6 ADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDES 140 150 160 170 180 190 230 240 250 260 270 pF1KB6 LFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED 200 210 220 230 240 >>NP_115590 (OMIM: 606577) src-like-adapter 2 isoform a (261 aa) initn: 651 init1: 334 opt: 630 Z-score: 694.2 bits: 136.2 E(85289): 6.3e-32 Smith-Waterman score: 630; 42.8% identity (66.9% similar) in 257 aa overlap (6-248:9-259) 10 20 30 40 pF1KB6 MGNSMKSTPAPA-------ERPLPNPEGLDSDFLAV-LSDYPSPDISPPIFRRGEKL :: :.:. . :. :. : :: :...:. . .: :: : NP_115 MGSLPSRRKSLPSPSLSSSVQGQGPVTM-EAERSKATAVALGSFPAGGPAELSLRLGEPL 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 RVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFM ..:..: :: ..: .::: ::.. ::.: ::::.:::.:.:::::: :: . :.:. NP_115 TIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 IRESETKKGFYSLSVRHRQ------VKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEV ::::.:..: :::::: . ..:::: : :.: :::::::: :. ::.::::. NP_115 IRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSEL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 ADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDES :: .::.: ::. : .. . :::... ..:. .:. . .: : .:: NP_115 ADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWK---ELDSSLLFSEAATG-EES 180 190 200 210 220 230 230 240 250 260 270 pF1KB6 LFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED :.: :::::.. :.::..: .:.: NP_115 LLSEGLRESLSFYISLNDE-AVSLDDA 240 250 260 >>XP_016883587 (OMIM: 606577) PREDICTED: src-like-adapte (288 aa) initn: 491 init1: 334 opt: 475 Z-score: 524.9 bits: 105.0 E(85289): 1.7e-22 Smith-Waterman score: 480; 38.2% identity (59.3% similar) in 285 aa overlap (6-265:9-286) 10 20 30 40 pF1KB6 MGNSMKSTPAPA-------ERPLPNPEGLDSDFLAV-LSDYPSPDISPPIFRRGEKL :: :.:. . :. . :. : :: :...:. . .: :: : XP_016 MGSLPSRRKSLPSPSLSSSVQGQGPV-TMEAERSKATAVALGSFPAGGPAELSLRLGEPL 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 RVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFM ..:..: :: ..: .::: ::.. ::.: ::::.:::.:.:::::: :: . :.:. XP_016 TIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 IRESETKKGFYSLSVRHRQ------VKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEV ::::.:..: :::::: . ..:::: : :.: :::::::: :. ::.:::. XP_016 IRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSDR 120 130 140 150 160 170 170 180 190 200 210 pF1KB6 A-DGLCCVLTTPCLTQSTAAPAVR--ASSSPVTLRQK--TVDWRRVSRLQEDPEGTENPL .:: : . : : : : ::: .: .: : . : . .:: XP_016 QKSGL------PYFHASPYAKKCRLGALSSPRALAEKPQTSCVGSGQYLAYHSGSDSEPL 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB6 GVDESLFS-YGLRESIA--SYLSLTSED-NTSFDR--KKKSISLMYGGSKRKSSFFSSPP .. . : . : : . . : :.: : . ::.: : .:.. :: . .. XP_016 AAGRVLSTGTGHRAAAVWDSILTLLSTSWCLSFNRHWKMQSLGTASGGREGRALL 240 250 260 270 280 pF1KB6 YFED >>NP_778252 (OMIM: 606577) src-like-adapter 2 isoform b (210 aa) initn: 495 init1: 334 opt: 472 Z-score: 523.7 bits: 104.3 E(85289): 2e-22 Smith-Waterman score: 472; 46.8% identity (68.4% similar) in 171 aa overlap (6-162:9-178) 10 20 30 40 pF1KB6 MGNSMKSTPAPA-------ERPLPNPEGLDSDFLAV-LSDYPSPDISPPIFRRGEKL :: :.:. . :. . :. : :: :...:. . .: :: : NP_778 MGSLPSRRKSLPSPSLSSSVQGQGPV-TMEAERSKATAVALGSFPAGGPAELSLRLGEPL 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 RVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFM ..:..: :: ..: .::: ::.. ::.: ::::.:::.:.:::::: :: . :.:. NP_778 TIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 IRESETKKGFYSLSVRHRQ------VKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEV ::::.:..: :::::: . ..:::: : :.: :::::::: :. ::.:::: NP_778 IRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSEG 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 ADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDES NP_778 WPAPWQGYTPTCDCAEDTTQLERAGQLPPVF 180 190 200 210 >>XP_011539756 (OMIM: 153390,615758) PREDICTED: tyrosine (516 aa) initn: 374 init1: 138 opt: 390 Z-score: 428.7 bits: 88.0 E(85289): 3.9e-17 Smith-Waterman score: 398; 35.5% identity (60.6% similar) in 251 aa overlap (9-242:107-354) 10 20 30 pF1KB6 MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDY-PSPD : ::. : : . .... .: .: :: : XP_011 SLAVGFHLSPTYFLPGLAFLVPHPVTPGFLPIPARFSL-MPLVFTDNLVIALHSYEPSHD 80 90 100 110 120 130 40 50 60 70 80 90 pF1KB6 ISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVY----HGWLFEGLGRDK . :..::.::.. . : :::: ::.::.:..:: ::.. . :.:..:.: XP_011 -GDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKD 140 150 160 170 180 190 100 110 120 130 140 pF1KB6 AEELLQLPDTKVGSFMIRESETKKGFYSLSVR---HRQ---VKHYRIFRLPNNWYYISPR ::. : : . :::.:::::. : .::::: . : ::::.: : :. .::::: XP_011 AERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPR 200 210 220 230 240 250 150 160 170 180 190 200 pF1KB6 LTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAP-AVRASSSPVTLRQKTVDWRRVSR .:: :..:: ::.. .: : .. : :.. .: : : .. . :. : . XP_011 ITFPGLHELVRHYTRYYNGHTKV-AVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAV 260 270 280 290 300 310 210 220 230 240 250 260 pF1KB6 LQEDP-----EGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGS . ..: : :: :: :.. .: . :..... XP_011 VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLR 320 330 340 350 360 370 270 pF1KB6 KRKSSFFSSPPYFED XP_011 AANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSF 380 390 400 410 420 430 276 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:47:26 2016 done: Fri Nov 4 20:47:27 2016 Total Scan time: 7.850 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]