FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6395, 276 aa
1>>>pF1KB6395 276 - 276 aa - 276 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2131+/-0.000806; mu= 16.1298+/- 0.049
mean_var=67.4074+/-13.612, 0's: 0 Z-trim(108.0): 26 B-trim: 0 in 0/52
Lambda= 0.156214
statistics sampled from 9887 (9911) to 9887 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.304), width: 16
Scan time: 2.450
The best scores are: opt bits E(32554)
CCDS4757.1 PSMB8 gene_id:5696|Hs108|chr6 ( 276) 1878 431.8 2.6e-121
CCDS4756.1 PSMB8 gene_id:5696|Hs108|chr6 ( 272) 1549 357.6 5.4e-99
CCDS9584.1 PSMB5 gene_id:5693|Hs108|chr14 ( 263) 1010 236.1 1.9e-62
CCDS41923.1 PSMB11 gene_id:122706|Hs108|chr14 ( 300) 797 188.2 6.1e-48
CCDS45083.1 PSMB5 gene_id:5693|Hs108|chr14 ( 160) 761 179.9 1e-45
CCDS45084.1 PSMB5 gene_id:5693|Hs108|chr14 ( 203) 614 146.8 1.2e-35
CCDS4759.1 PSMB9 gene_id:5698|Hs108|chr6 ( 219) 337 84.4 7.6e-17
CCDS11056.1 PSMB6 gene_id:5694|Hs108|chr17 ( 239) 331 83.1 2.1e-16
CCDS10853.1 PSMB10 gene_id:5699|Hs108|chr16 ( 273) 288 73.4 1.9e-13
CCDS6855.1 PSMB7 gene_id:5695|Hs108|chr9 ( 277) 284 72.5 3.6e-13
CCDS73944.1 PSMB6 gene_id:5694|Hs108|chr17 ( 213) 266 68.4 4.9e-12
>>CCDS4757.1 PSMB8 gene_id:5696|Hs108|chr6 (276 aa)
initn: 1878 init1: 1878 opt: 1878 Z-score: 2291.3 bits: 431.8 E(32554): 2.6e-121
Smith-Waterman score: 1878; 100.0% identity (100.0% similar) in 276 aa overlap (1-276:1-276)
10 20 30 40 50 60
pF1KB6 MALLDVCGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MALLDVCGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 GERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 AADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 AADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 PGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDS
190 200 210 220 230 240
250 260 270
pF1KB6 YSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ
::::::::::::::::::::::::::::::::::::
CCDS47 YSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ
250 260 270
>>CCDS4756.1 PSMB8 gene_id:5696|Hs108|chr6 (272 aa)
initn: 1549 init1: 1549 opt: 1549 Z-score: 1890.7 bits: 357.6 E(32554): 5.4e-99
Smith-Waterman score: 1549; 99.1% identity (100.0% similar) in 230 aa overlap (47-276:43-272)
20 30 40 50 60 70
pF1KB6 SALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTL
:..:::::::::::::::::::::::::::
CCDS47 PSSWLTSSLLVEAAPLDDTTLPTPVSSGCPGLEPTEFFQSLGGDGERNVQIEMAHGTTTL
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB6 AFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 AFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECR
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB6 LYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGN
140 150 160 170 180 190
200 210 220 230 240 250
pF1KB6 MFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGW
200 210 220 230 240 250
260 270
pF1KB6 VKVESTDVSDLLHQYREANQ
::::::::::::::::::::
CCDS47 VKVESTDVSDLLHQYREANQ
260 270
>>CCDS9584.1 PSMB5 gene_id:5693|Hs108|chr14 (263 aa)
initn: 1028 init1: 1009 opt: 1010 Z-score: 1234.4 bits: 236.1 E(32554): 1.9e-62
Smith-Waterman score: 1010; 62.4% identity (83.1% similar) in 242 aa overlap (31-271:17-258)
10 20 30 40 50 60
pF1KB6 MALLDVCGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGD
: .... :. : : : . . :
CCDS95 MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGW
10 20 30 40
70 80 90 100 110
pF1KB6 G-ERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSG
: .. ::: ::::::::::.::::.:.::::.::.::.. :.:::::::::::::.:
CCDS95 GVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 CAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKK
::::..::::::..::.: ::: :::::.::::::.::. ::.:::::::.:::::::.
CCDS95 GAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 GPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRD
:::::::: .:.:.:: ::.:::..::::::: :: .: :.::::.:::: ::.::
CCDS95 GPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRD
170 180 190 200 210 220
240 250 260 270
pF1KB6 SYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ
.::::.::.::..::::..: : .:.:: ..:
CCDS95 AYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
230 240 250 260
>>CCDS41923.1 PSMB11 gene_id:122706|Hs108|chr14 (300 aa)
initn: 857 init1: 769 opt: 797 Z-score: 974.2 bits: 188.2 E(32554): 6.1e-48
Smith-Waterman score: 817; 49.4% identity (69.4% similar) in 265 aa overlap (1-263:1-240)
10 20 30 40 50
pF1KB6 MALLDVCG--APRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLG
::: ::: .: : : :: ::. :.::: .: :.:
CCDS41 MALQDVCKWQSPDTQGPSPHLPRAGG-----------------WAVPRGCDPQTFLQI--
10 20 30 40
60 70 80 90 100 110
pF1KB6 GDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMS
: : .:::::::::.:.::::::.:.:.: :::.. ::: .. .:::: :
CCDS41 -HGPR-----LAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTS
50 60 70 80 90
120 130 140 150 160 170
pF1KB6 GCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDK
: .::: : :.: .: :: ::.:. ::..:.:::: :: ::::. : ... .::::.
CCDS41 GTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB6 KGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHR
.:: :.:: ::::.:..::.:::. :::::.: ::: ..: .::: :.: :.:.::::
CCDS41 SGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHR
160 170 180 190 200 210
240 250 260 270
pF1KB6 DSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ
:.:::: :...:..:.:: .: .:
CCDS41 DAYSGGSVDLFHVRESGWEHVSRSDACVLYVELQKLLEPEPEEDASHAHPEPATAHRAAE
220 230 240 250 260 270
>>CCDS45083.1 PSMB5 gene_id:5693|Hs108|chr14 (160 aa)
initn: 763 init1: 748 opt: 761 Z-score: 934.3 bits: 179.9 E(32554): 1e-45
Smith-Waterman score: 761; 67.7% identity (89.0% similar) in 155 aa overlap (117-271:1-155)
90 100 110 120 130 140
pF1KB6 AVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERI
:.: ::::..::::::..::.: ::: :::
CCDS45 MAGGAADCSFWERLLARQCRIYELRNKERI
10 20 30
150 160 170 180 190 200
pF1KB6 SVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTY
::.::::::.::. ::.:::::::.:::::::.:::::::: .:.:.:: ::.:::..:
CCDS45 SVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVY
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB6 AYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSD
:::::: :: .: :.::::.:::: ::.::.::::.::.::..::::..: : .:.:
CCDS45 AYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVAD
100 110 120 130 140 150
270
pF1KB6 LLHQYREANQ
: ..:
CCDS45 LHEKYSGSTP
160
>>CCDS45084.1 PSMB5 gene_id:5693|Hs108|chr14 (203 aa)
initn: 613 init1: 613 opt: 614 Z-score: 753.7 bits: 146.8 E(32554): 1.2e-35
Smith-Waterman score: 614; 62.5% identity (81.6% similar) in 152 aa overlap (31-181:17-168)
10 20 30 40 50 60
pF1KB6 MALLDVCGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGD
: .... :. : : : . . :
CCDS45 MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGW
10 20 30 40
70 80 90 100 110
pF1KB6 G-ERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSG
: .. ::: ::::::::::.::::.:.::::.::.::.. :.:::::::::::::.:
CCDS45 GVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 CAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKK
::::..::::::..::.: ::: :::::.::::::.::. ::.:::::::.:::::::.
CCDS45 GAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 GPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRD
::
CCDS45 GPVSEVLCLKPKSFGMYLFCGCAERIGNMARPLLRGQ
170 180 190 200
>>CCDS4759.1 PSMB9 gene_id:5698|Hs108|chr6 (219 aa)
initn: 354 init1: 197 opt: 337 Z-score: 415.9 bits: 84.4 E(32554): 7.6e-17
Smith-Waterman score: 337; 33.8% identity (58.1% similar) in 198 aa overlap (59-255:9-202)
30 40 50 60 70 80
pF1KB6 DPGHYSFSMRSPELALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAV
:: : ... ::: .: .:. ::. .
CCDS47 MLRAGAPTGDLPRAGEVHT--GTTIMAVEFDGGVVMGS
10 20 30
90 100 110 120 130 140
pF1KB6 DSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISV
:::.::: . .:. .. . ..:: ::: : . : . .:. .. : :
CCDS47 DSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAAYQLELHGIELEEPPLV
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 SAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTG-SGNTYA
::.... :. .:: :: :. :::.. : : : :. . :. : ::.:.
CCDS47 LAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVY-GTLGGMLTRQPFAIGGSGSTFI
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 YGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDL
:: .:..:.:..:::: . ::: : ::. ::::. . . :
CCDS47 YGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTITAAGVDHRVILGNELP
160 170 180 190 200 210
270
pF1KB6 LHQYREANQ
CCDS47 KFYDE
>>CCDS11056.1 PSMB6 gene_id:5694|Hs108|chr17 (239 aa)
initn: 322 init1: 280 opt: 331 Z-score: 408.0 bits: 83.1 E(32554): 2.1e-16
Smith-Waterman score: 331; 32.8% identity (62.4% similar) in 189 aa overlap (68-255:30-217)
40 50 60 70 80 90
pF1KB6 RSPELALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSY
:.. ::: .: .:. ::. ..:::...:::
CCDS11 MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSY
10 20 30 40 50
100 110 120 130 140 150
pF1KB6 ISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSN
:. ..:. :. .. :: ::: : .. . .. .. .: : .:..:...
CCDS11 IANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKE
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB6 MMCQYRGMGLSMGSMICGWD-KKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYR
: .:: : : .: ::: ..: .: : : . .. :::..: :: .:. ::
CCDS11 MCYRYR-EDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYR
120 130 140 150 160 170
220 230 240 250 260 270
pF1KB6 PNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ
... :: .. :.: : .::. ::::. . . :.:
CCDS11 EGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPP
180 190 200 210 220 230
CCDS11 A
>>CCDS10853.1 PSMB10 gene_id:5699|Hs108|chr16 (273 aa)
initn: 269 init1: 162 opt: 288 Z-score: 354.8 bits: 73.4 E(32554): 1.9e-13
Smith-Waterman score: 288; 29.8% identity (58.2% similar) in 225 aa overlap (37-255:1-221)
10 20 30 40 50 60
pF1KB6 CGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGDGERNVQ
: .: : ::: : : ... :: .
CCDS10 MLKPALE-PRGGFSFENCQR-NASLERVLP
10 20
70 80 90 100 110 120
pF1KB6 -IEMAH----GTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCA
... : ::: .. :: ::: ..:.::. : .. .:. : : . .: :
CCDS10 GLKVPHARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVA
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB6 ADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRG-MGLSMGSMICGWDKKG
:: .. :..:.. .:. : .:.. :......: . . .:.: .: :. .. : : :
CCDS10 ADAEMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASL--IVGGVDLTG
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB6 PGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDS
: :: : ::. . . :::. : .:... ..::.. : : : .:.. . :
CCDS10 PQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDL
150 160 170 180 190 200
250 260 270
pF1KB6 YSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ
::: :. . . :
CCDS10 GSGGNVDACVITKTGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEET
210 220 230 240 250 260
>>CCDS6855.1 PSMB7 gene_id:5695|Hs108|chr9 (277 aa)
initn: 217 init1: 137 opt: 284 Z-score: 349.8 bits: 72.5 E(32554): 3.6e-13
Smith-Waterman score: 284; 28.2% identity (63.8% similar) in 177 aa overlap (72-248:43-218)
50 60 70 80 90 100
pF1KB6 LALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISAL
::: . .. :.. ..:.::. : ..
CCDS68 GFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADK
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB6 RVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQ
.:. :.: . .: ::: .. .:.... .:. : .:. : .:...:..:. .
CCDS68 NCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFR
80 90 100 110 120 130
170 180 190 200 210 220
pF1KB6 YRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSP
:.:. .. . .. : : :: :: . ::. . . . :::. :..:... .::..
CCDS68 YQGY-IGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEE
140 150 160 170 180 190
230 240 250 260 270
pF1KB6 EEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ
::: .: .::: . : ::. ...
CCDS68 EEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGT
200 210 220 230 240 250
276 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:48:07 2016 done: Fri Nov 4 20:48:07 2016
Total Scan time: 2.450 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]