FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6395, 276 aa 1>>>pF1KB6395 276 - 276 aa - 276 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2131+/-0.000806; mu= 16.1298+/- 0.049 mean_var=67.4074+/-13.612, 0's: 0 Z-trim(108.0): 26 B-trim: 0 in 0/52 Lambda= 0.156214 statistics sampled from 9887 (9911) to 9887 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.304), width: 16 Scan time: 2.450 The best scores are: opt bits E(32554) CCDS4757.1 PSMB8 gene_id:5696|Hs108|chr6 ( 276) 1878 431.8 2.6e-121 CCDS4756.1 PSMB8 gene_id:5696|Hs108|chr6 ( 272) 1549 357.6 5.4e-99 CCDS9584.1 PSMB5 gene_id:5693|Hs108|chr14 ( 263) 1010 236.1 1.9e-62 CCDS41923.1 PSMB11 gene_id:122706|Hs108|chr14 ( 300) 797 188.2 6.1e-48 CCDS45083.1 PSMB5 gene_id:5693|Hs108|chr14 ( 160) 761 179.9 1e-45 CCDS45084.1 PSMB5 gene_id:5693|Hs108|chr14 ( 203) 614 146.8 1.2e-35 CCDS4759.1 PSMB9 gene_id:5698|Hs108|chr6 ( 219) 337 84.4 7.6e-17 CCDS11056.1 PSMB6 gene_id:5694|Hs108|chr17 ( 239) 331 83.1 2.1e-16 CCDS10853.1 PSMB10 gene_id:5699|Hs108|chr16 ( 273) 288 73.4 1.9e-13 CCDS6855.1 PSMB7 gene_id:5695|Hs108|chr9 ( 277) 284 72.5 3.6e-13 CCDS73944.1 PSMB6 gene_id:5694|Hs108|chr17 ( 213) 266 68.4 4.9e-12 >>CCDS4757.1 PSMB8 gene_id:5696|Hs108|chr6 (276 aa) initn: 1878 init1: 1878 opt: 1878 Z-score: 2291.3 bits: 431.8 E(32554): 2.6e-121 Smith-Waterman score: 1878; 100.0% identity (100.0% similar) in 276 aa overlap (1-276:1-276) 10 20 30 40 50 60 pF1KB6 MALLDVCGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MALLDVCGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 GERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 AADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 AADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDS 190 200 210 220 230 240 250 260 270 pF1KB6 YSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ :::::::::::::::::::::::::::::::::::: CCDS47 YSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ 250 260 270 >>CCDS4756.1 PSMB8 gene_id:5696|Hs108|chr6 (272 aa) initn: 1549 init1: 1549 opt: 1549 Z-score: 1890.7 bits: 357.6 E(32554): 5.4e-99 Smith-Waterman score: 1549; 99.1% identity (100.0% similar) in 230 aa overlap (47-276:43-272) 20 30 40 50 60 70 pF1KB6 SALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTL :..::::::::::::::::::::::::::: CCDS47 PSSWLTSSLLVEAAPLDDTTLPTPVSSGCPGLEPTEFFQSLGGDGERNVQIEMAHGTTTL 20 30 40 50 60 70 80 90 100 110 120 130 pF1KB6 AFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 AFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECR 80 90 100 110 120 130 140 150 160 170 180 190 pF1KB6 LYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGN 140 150 160 170 180 190 200 210 220 230 240 250 pF1KB6 MFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGW 200 210 220 230 240 250 260 270 pF1KB6 VKVESTDVSDLLHQYREANQ :::::::::::::::::::: CCDS47 VKVESTDVSDLLHQYREANQ 260 270 >>CCDS9584.1 PSMB5 gene_id:5693|Hs108|chr14 (263 aa) initn: 1028 init1: 1009 opt: 1010 Z-score: 1234.4 bits: 236.1 E(32554): 1.9e-62 Smith-Waterman score: 1010; 62.4% identity (83.1% similar) in 242 aa overlap (31-271:17-258) 10 20 30 40 50 60 pF1KB6 MALLDVCGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGD : .... :. : : : . . : CCDS95 MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGW 10 20 30 40 70 80 90 100 110 pF1KB6 G-ERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSG : .. ::: ::::::::::.::::.:.::::.::.::.. :.:::::::::::::.: CCDS95 GVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAG 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 CAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKK ::::..::::::..::.: ::: :::::.::::::.::. ::.:::::::.:::::::. CCDS95 GAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 GPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRD :::::::: .:.:.:: ::.:::..::::::: :: .: :.::::.:::: ::.:: CCDS95 GPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRD 170 180 190 200 210 220 240 250 260 270 pF1KB6 SYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ .::::.::.::..::::..: : .:.:: ..: CCDS95 AYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP 230 240 250 260 >>CCDS41923.1 PSMB11 gene_id:122706|Hs108|chr14 (300 aa) initn: 857 init1: 769 opt: 797 Z-score: 974.2 bits: 188.2 E(32554): 6.1e-48 Smith-Waterman score: 817; 49.4% identity (69.4% similar) in 265 aa overlap (1-263:1-240) 10 20 30 40 50 pF1KB6 MALLDVCG--APRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLG ::: ::: .: : : :: ::. :.::: .: :.: CCDS41 MALQDVCKWQSPDTQGPSPHLPRAGG-----------------WAVPRGCDPQTFLQI-- 10 20 30 40 60 70 80 90 100 110 pF1KB6 GDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMS : : .:::::::::.:.::::::.:.:.: :::.. ::: .. .:::: : CCDS41 -HGPR-----LAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTS 50 60 70 80 90 120 130 140 150 160 170 pF1KB6 GCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDK : .::: : :.: .: :: ::.:. ::..:.:::: :: ::::. : ... .::::. CCDS41 GTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDR 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB6 KGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHR .:: :.:: ::::.:..::.:::. :::::.: ::: ..: .::: :.: :.:.:::: CCDS41 SGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHR 160 170 180 190 200 210 240 250 260 270 pF1KB6 DSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ :.:::: :...:..:.:: .: .: CCDS41 DAYSGGSVDLFHVRESGWEHVSRSDACVLYVELQKLLEPEPEEDASHAHPEPATAHRAAE 220 230 240 250 260 270 >>CCDS45083.1 PSMB5 gene_id:5693|Hs108|chr14 (160 aa) initn: 763 init1: 748 opt: 761 Z-score: 934.3 bits: 179.9 E(32554): 1e-45 Smith-Waterman score: 761; 67.7% identity (89.0% similar) in 155 aa overlap (117-271:1-155) 90 100 110 120 130 140 pF1KB6 AVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERI :.: ::::..::::::..::.: ::: ::: CCDS45 MAGGAADCSFWERLLARQCRIYELRNKERI 10 20 30 150 160 170 180 190 200 pF1KB6 SVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTY ::.::::::.::. ::.:::::::.:::::::.:::::::: .:.:.:: ::.:::..: CCDS45 SVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVY 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB6 AYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSD :::::: :: .: :.::::.:::: ::.::.::::.::.::..::::..: : .:.: CCDS45 AYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVAD 100 110 120 130 140 150 270 pF1KB6 LLHQYREANQ : ..: CCDS45 LHEKYSGSTP 160 >>CCDS45084.1 PSMB5 gene_id:5693|Hs108|chr14 (203 aa) initn: 613 init1: 613 opt: 614 Z-score: 753.7 bits: 146.8 E(32554): 1.2e-35 Smith-Waterman score: 614; 62.5% identity (81.6% similar) in 152 aa overlap (31-181:17-168) 10 20 30 40 50 60 pF1KB6 MALLDVCGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGD : .... :. : : : . . : CCDS45 MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGW 10 20 30 40 70 80 90 100 110 pF1KB6 G-ERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSG : .. ::: ::::::::::.::::.:.::::.::.::.. :.:::::::::::::.: CCDS45 GVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAG 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 CAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKK ::::..::::::..::.: ::: :::::.::::::.::. ::.:::::::.:::::::. CCDS45 GAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 GPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRD :: CCDS45 GPVSEVLCLKPKSFGMYLFCGCAERIGNMARPLLRGQ 170 180 190 200 >>CCDS4759.1 PSMB9 gene_id:5698|Hs108|chr6 (219 aa) initn: 354 init1: 197 opt: 337 Z-score: 415.9 bits: 84.4 E(32554): 7.6e-17 Smith-Waterman score: 337; 33.8% identity (58.1% similar) in 198 aa overlap (59-255:9-202) 30 40 50 60 70 80 pF1KB6 DPGHYSFSMRSPELALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAV :: : ... ::: .: .:. ::. . CCDS47 MLRAGAPTGDLPRAGEVHT--GTTIMAVEFDGGVVMGS 10 20 30 90 100 110 120 130 140 pF1KB6 DSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISV :::.::: . .:. .. . ..:: ::: : . : . .:. .. : : CCDS47 DSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAAYQLELHGIELEEPPLV 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 SAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTG-SGNTYA ::.... :. .:: :: :. :::.. : : : :. . :. : ::.:. CCDS47 LAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVY-GTLGGMLTRQPFAIGGSGSTFI 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 YGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDL :: .:..:.:..:::: . ::: : ::. ::::. . . : CCDS47 YGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTITAAGVDHRVILGNELP 160 170 180 190 200 210 270 pF1KB6 LHQYREANQ CCDS47 KFYDE >>CCDS11056.1 PSMB6 gene_id:5694|Hs108|chr17 (239 aa) initn: 322 init1: 280 opt: 331 Z-score: 408.0 bits: 83.1 E(32554): 2.1e-16 Smith-Waterman score: 331; 32.8% identity (62.4% similar) in 189 aa overlap (68-255:30-217) 40 50 60 70 80 90 pF1KB6 RSPELALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSY :.. ::: .: .:. ::. ..:::...::: CCDS11 MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSY 10 20 30 40 50 100 110 120 130 140 150 pF1KB6 ISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSN :. ..:. :. .. :: ::: : .. . .. .. .: : .:..:... CCDS11 IANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKE 60 70 80 90 100 110 160 170 180 190 200 210 pF1KB6 MMCQYRGMGLSMGSMICGWD-KKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYR : .:: : : .: ::: ..: .: : : . .. :::..: :: .:. :: CCDS11 MCYRYR-EDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYR 120 130 140 150 160 170 220 230 240 250 260 270 pF1KB6 PNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ ... :: .. :.: : .::. ::::. . . :.: CCDS11 EGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPP 180 190 200 210 220 230 CCDS11 A >>CCDS10853.1 PSMB10 gene_id:5699|Hs108|chr16 (273 aa) initn: 269 init1: 162 opt: 288 Z-score: 354.8 bits: 73.4 E(32554): 1.9e-13 Smith-Waterman score: 288; 29.8% identity (58.2% similar) in 225 aa overlap (37-255:1-221) 10 20 30 40 50 60 pF1KB6 CGAPRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLGGDGERNVQ : .: : ::: : : ... :: . CCDS10 MLKPALE-PRGGFSFENCQR-NASLERVLP 10 20 70 80 90 100 110 120 pF1KB6 -IEMAH----GTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCA ... : ::: .. :: ::: ..:.::. : .. .:. : : . .: : CCDS10 GLKVPHARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVA 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB6 ADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRG-MGLSMGSMICGWDKKG :: .. :..:.. .:. : .:.. :......: . . .:.: .: :. .. : : : CCDS10 ADAEMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASL--IVGGVDLTG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB6 PGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDS : :: : ::. . . :::. : .:... ..::.. : : : .:.. . : CCDS10 PQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDL 150 160 170 180 190 200 250 260 270 pF1KB6 YSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ ::: :. . . : CCDS10 GSGGNVDACVITKTGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEET 210 220 230 240 250 260 >>CCDS6855.1 PSMB7 gene_id:5695|Hs108|chr9 (277 aa) initn: 217 init1: 137 opt: 284 Z-score: 349.8 bits: 72.5 E(32554): 3.6e-13 Smith-Waterman score: 284; 28.2% identity (63.8% similar) in 177 aa overlap (72-248:43-218) 50 60 70 80 90 100 pF1KB6 LALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISAL ::: . .. :.. ..:.::. : .. CCDS68 GFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADK 20 30 40 50 60 70 110 120 130 140 150 160 pF1KB6 RVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQ .:. :.: . .: ::: .. .:.... .:. : .:. : .:...:..:. . CCDS68 NCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFR 80 90 100 110 120 130 170 180 190 200 210 220 pF1KB6 YRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSP :.:. .. . .. : : :: :: . ::. . . . :::. :..:... .::.. CCDS68 YQGY-IGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEE 140 150 160 170 180 190 230 240 250 260 270 pF1KB6 EEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ ::: .: .::: . : ::. ... CCDS68 EEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGT 200 210 220 230 240 250 276 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:48:07 2016 done: Fri Nov 4 20:48:07 2016 Total Scan time: 2.450 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]