Result of FASTA (omim) for
pF1KB6396
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6396, 304 aa
1>>>pF1KB6396 304 - 304 aa - 304 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2165+/-0.000288; mu= 7.7240+/- 0.018
mean_var=122.0657+/-24.589, 0's: 0 Z-trim(121.7): 14 B-trim: 1873 in 1/55
Lambda= 0.116085
statistics sampled from 38714 (38729) to 38714 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.454), width: 16
Scan time: 8.940
The best scores are: opt bits E(85289)
NP_060659 (OMIM: 614125) developmental pluripotenc ( 304) 2047 353.1 4e-97
XP_011511256 (OMIM: 614125) PREDICTED: development ( 252) 1722 298.6 8.4e-81
XP_011510747 (OMIM: 614445) PREDICTED: development ( 298) 574 106.4 7.3e-23
XP_011510746 (OMIM: 614445) PREDICTED: development ( 298) 574 106.4 7.3e-23
NP_620170 (OMIM: 614445) developmental pluripotenc ( 298) 574 106.4 7.3e-23
XP_011510745 (OMIM: 614445) PREDICTED: development ( 307) 574 106.4 7.4e-23
>>NP_060659 (OMIM: 614125) developmental pluripotency-as (304 aa)
initn: 2047 init1: 2047 opt: 2047 Z-score: 1864.6 bits: 353.1 E(85289): 4e-97
Smith-Waterman score: 2047; 99.7% identity (100.0% similar) in 304 aa overlap (1-304:1-304)
10 20 30 40 50 60
pF1KB6 MLRGSASSTSMEKAKGKEWTSTEKSREEDQQASNQPNSIALPGTSAKRTKEKMSVKGSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
NP_060 MLRGSASSTSMEKAKGKEWTSTEKSREEDQQASNQPNSIALPGTSAKRTKEKMSIKGSKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LCPKKKAEHTDNPRPQKKIPIPPLPSKLPPVNLIHRDILRAWCQQLKLSSKGQKLDAYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LCPKKKAEHTDNPRPQKKIPIPPLPSKLPPVNLIHRDILRAWCQQLKLSSKGQKLDAYKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCAFAYPNQKDFPSTAKEAKIRKSLQKKLKVEKGETSLQSSETHPPEVALPPVGEPPALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LCAFAYPNQKDFPSTAKEAKIRKSLQKKLKVEKGETSLQSSETHPPEVALPPVGEPPALE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NSTALLEGVNTVVVTTSAPEALLASWARISARARTPEAVESPQEASGVRWCVVHGKSLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NSTALLEGVNTVVVTTSAPEALLASWARISARARTPEAVESPQEASGVRWCVVHGKSLPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 DTDGWVHLQFHAGQAWVPEKQEGRVSALFLLPASNFPPPHLEDNMLCPKCVHRNKVLIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DTDGWVHLQFHAGQAWVPEKQEGRVSALFLLPASNFPPPHLEDNMLCPKCVHRNKVLIKS
250 260 270 280 290 300
pF1KB6 LQWE
::::
NP_060 LQWE
>>XP_011511256 (OMIM: 614125) PREDICTED: developmental p (252 aa)
initn: 1722 init1: 1722 opt: 1722 Z-score: 1571.7 bits: 298.6 E(85289): 8.4e-81
Smith-Waterman score: 1722; 99.6% identity (100.0% similar) in 252 aa overlap (53-304:1-252)
30 40 50 60 70 80
pF1KB6 EKSREEDQQASNQPNSIALPGTSAKRTKEKMSVKGSKVLCPKKKAEHTDNPRPQKKIPIP
::.:::::::::::::::::::::::::::
XP_011 MSIKGSKVLCPKKKAEHTDNPRPQKKIPIP
10 20 30
90 100 110 120 130 140
pF1KB6 PLPSKLPPVNLIHRDILRAWCQQLKLSSKGQKLDAYKRLCAFAYPNQKDFPSTAKEAKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPSKLPPVNLIHRDILRAWCQQLKLSSKGQKLDAYKRLCAFAYPNQKDFPSTAKEAKIR
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 KSLQKKLKVEKGETSLQSSETHPPEVALPPVGEPPALENSTALLEGVNTVVVTTSAPEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLQKKLKVEKGETSLQSSETHPPEVALPPVGEPPALENSTALLEGVNTVVVTTSAPEAL
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 LASWARISARARTPEAVESPQEASGVRWCVVHGKSLPADTDGWVHLQFHAGQAWVPEKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASWARISARARTPEAVESPQEASGVRWCVVHGKSLPADTDGWVHLQFHAGQAWVPEKQE
160 170 180 190 200 210
270 280 290 300
pF1KB6 GRVSALFLLPASNFPPPHLEDNMLCPKCVHRNKVLIKSLQWE
::::::::::::::::::::::::::::::::::::::::::
XP_011 GRVSALFLLPASNFPPPHLEDNMLCPKCVHRNKVLIKSLQWE
220 230 240 250
>>XP_011510747 (OMIM: 614445) PREDICTED: developmental p (298 aa)
initn: 691 init1: 222 opt: 574 Z-score: 531.5 bits: 106.4 E(85289): 7.3e-23
Smith-Waterman score: 693; 49.8% identity (67.2% similar) in 241 aa overlap (75-301:73-293)
50 60 70 80 90 100
pF1KB6 SAKRTKEKMSVKGSKVLCPKKKAEHTDNPRPQK---KIPIPPLPSKLPPVNLIHRDILRA
::: ::: :::. :::.: . :: ::
XP_011 SVSSTSDVKLEKPKKYNPGHLLQTNEQFTAPQKARCKIPALPLPTILPPINKVCRDTLRD
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB6 WCQQLKLSSKGQKLDAYKRLCAFAYPNQK-DFPSTAKEAKIRKSLQKKLKVEKGETSLQS
::::: ::..:.:...: :: :::.:. :.: ..:..... .:. : : .. ::
XP_011 WCQQLGLSTNGKKIEVYLRLHRHAYPEQRQDMPEMSQETRLQRCSRKRKAVTK-RARLQR
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 SETHPPEVALPPVGEPPALENSTALLEGVNTVVVTTSAPEALLASWARISARARTPEAVE
: : : : .::: : :::: :.:::::::.::: :.:..
XP_011 SYEM----------------NERA--EETNTVEVITSAPGAMLASWARIAARAVQPKALN
170 180 190 200
230 240 250 260 270
pF1KB6 S---P-------QEASGVRWCVVHGKSLPADTDGWVHLQFHAGQAWVPEKQEGRVSALFL
: : ..:::::::::::. : ::: :::.::::::::::: .. :. .:::
XP_011 SCSIPVSVEAFLMQASGVRWCVVHGRLLSADTKGWVRLQFHAGQAWVPTTHR-RMISLFL
210 220 230 240 250 260
280 290 300
pF1KB6 LPASNFPPPHLEDNMLCPKCVHRNKVLIKSLQWE
::: :: : .::::::: :..::: ..: :
XP_011 LPACIFPSPGIEDNMLCPDCAKRNKKMMKRLMTVEK
270 280 290
>>XP_011510746 (OMIM: 614445) PREDICTED: developmental p (298 aa)
initn: 691 init1: 222 opt: 574 Z-score: 531.5 bits: 106.4 E(85289): 7.3e-23
Smith-Waterman score: 693; 49.8% identity (67.2% similar) in 241 aa overlap (75-301:73-293)
50 60 70 80 90 100
pF1KB6 SAKRTKEKMSVKGSKVLCPKKKAEHTDNPRPQK---KIPIPPLPSKLPPVNLIHRDILRA
::: ::: :::. :::.: . :: ::
XP_011 SVSSTSDVKLEKPKKYNPGHLLQTNEQFTAPQKARCKIPALPLPTILPPINKVCRDTLRD
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB6 WCQQLKLSSKGQKLDAYKRLCAFAYPNQK-DFPSTAKEAKIRKSLQKKLKVEKGETSLQS
::::: ::..:.:...: :: :::.:. :.: ..:..... .:. : : .. ::
XP_011 WCQQLGLSTNGKKIEVYLRLHRHAYPEQRQDMPEMSQETRLQRCSRKRKAVTK-RARLQR
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 SETHPPEVALPPVGEPPALENSTALLEGVNTVVVTTSAPEALLASWARISARARTPEAVE
: : : : .::: : :::: :.:::::::.::: :.:..
XP_011 SYEM----------------NERA--EETNTVEVITSAPGAMLASWARIAARAVQPKALN
170 180 190 200
230 240 250 260 270
pF1KB6 S---P-------QEASGVRWCVVHGKSLPADTDGWVHLQFHAGQAWVPEKQEGRVSALFL
: : ..:::::::::::. : ::: :::.::::::::::: .. :. .:::
XP_011 SCSIPVSVEAFLMQASGVRWCVVHGRLLSADTKGWVRLQFHAGQAWVPTTHR-RMISLFL
210 220 230 240 250 260
280 290 300
pF1KB6 LPASNFPPPHLEDNMLCPKCVHRNKVLIKSLQWE
::: :: : .::::::: :..::: ..: :
XP_011 LPACIFPSPGIEDNMLCPDCAKRNKKMMKRLMTVEK
270 280 290
>>NP_620170 (OMIM: 614445) developmental pluripotency-as (298 aa)
initn: 691 init1: 222 opt: 574 Z-score: 531.5 bits: 106.4 E(85289): 7.3e-23
Smith-Waterman score: 693; 49.8% identity (67.2% similar) in 241 aa overlap (75-301:73-293)
50 60 70 80 90 100
pF1KB6 SAKRTKEKMSVKGSKVLCPKKKAEHTDNPRPQK---KIPIPPLPSKLPPVNLIHRDILRA
::: ::: :::. :::.: . :: ::
NP_620 SVSSTSDVKLEKPKKYNPGHLLQTNEQFTAPQKARCKIPALPLPTILPPINKVCRDTLRD
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB6 WCQQLKLSSKGQKLDAYKRLCAFAYPNQK-DFPSTAKEAKIRKSLQKKLKVEKGETSLQS
::::: ::..:.:...: :: :::.:. :.: ..:..... .:. : : .. ::
NP_620 WCQQLGLSTNGKKIEVYLRLHRHAYPEQRQDMPEMSQETRLQRCSRKRKAVTK-RARLQR
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 SETHPPEVALPPVGEPPALENSTALLEGVNTVVVTTSAPEALLASWARISARARTPEAVE
: : : : .::: : :::: :.:::::::.::: :.:..
NP_620 SYEM----------------NERA--EETNTVEVITSAPGAMLASWARIAARAVQPKALN
170 180 190 200
230 240 250 260 270
pF1KB6 S---P-------QEASGVRWCVVHGKSLPADTDGWVHLQFHAGQAWVPEKQEGRVSALFL
: : ..:::::::::::. : ::: :::.::::::::::: .. :. .:::
NP_620 SCSIPVSVEAFLMQASGVRWCVVHGRLLSADTKGWVRLQFHAGQAWVPTTHR-RMISLFL
210 220 230 240 250 260
280 290 300
pF1KB6 LPASNFPPPHLEDNMLCPKCVHRNKVLIKSLQWE
::: :: : .::::::: :..::: ..: :
NP_620 LPACIFPSPGIEDNMLCPDCAKRNKKMMKRLMTVEK
270 280 290
>>XP_011510745 (OMIM: 614445) PREDICTED: developmental p (307 aa)
initn: 691 init1: 222 opt: 574 Z-score: 531.3 bits: 106.4 E(85289): 7.4e-23
Smith-Waterman score: 693; 49.8% identity (67.2% similar) in 241 aa overlap (75-301:82-302)
50 60 70 80 90 100
pF1KB6 SAKRTKEKMSVKGSKVLCPKKKAEHTDNPRPQK---KIPIPPLPSKLPPVNLIHRDILRA
::: ::: :::. :::.: . :: ::
XP_011 SVSSTSDVKLEKPKKYNPGHLLQTNEQFTAPQKARCKIPALPLPTILPPINKVCRDTLRD
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 WCQQLKLSSKGQKLDAYKRLCAFAYPNQK-DFPSTAKEAKIRKSLQKKLKVEKGETSLQS
::::: ::..:.:...: :: :::.:. :.: ..:..... .:. : : .. ::
XP_011 WCQQLGLSTNGKKIEVYLRLHRHAYPEQRQDMPEMSQETRLQRCSRKRKAVTK-RARLQR
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 SETHPPEVALPPVGEPPALENSTALLEGVNTVVVTTSAPEALLASWARISARARTPEAVE
: : : : .::: : :::: :.:::::::.::: :.:..
XP_011 SYEM----------------NERA--EETNTVEVITSAPGAMLASWARIAARAVQPKALN
180 190 200 210
230 240 250 260 270
pF1KB6 S---P-------QEASGVRWCVVHGKSLPADTDGWVHLQFHAGQAWVPEKQEGRVSALFL
: : ..:::::::::::. : ::: :::.::::::::::: .. :. .:::
XP_011 SCSIPVSVEAFLMQASGVRWCVVHGRLLSADTKGWVRLQFHAGQAWVPTTHR-RMISLFL
220 230 240 250 260 270
280 290 300
pF1KB6 LPASNFPPPHLEDNMLCPKCVHRNKVLIKSLQWE
::: :: : .::::::: :..::: ..: :
XP_011 LPACIFPSPGIEDNMLCPDCAKRNKKMMKRLMTVEK
280 290 300
304 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:06:11 2016 done: Fri Nov 4 17:06:13 2016
Total Scan time: 8.940 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]