FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6401, 304 aa 1>>>pF1KB6401 304 - 304 aa - 304 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8219+/-0.00033; mu= 5.2061+/- 0.021 mean_var=145.2423+/-29.622, 0's: 0 Z-trim(120.0): 138 B-trim: 0 in 0/54 Lambda= 0.106421 statistics sampled from 34556 (34711) to 34556 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.754), E-opt: 0.2 (0.407), width: 16 Scan time: 5.640 The best scores are: opt bits E(85289) NP_057399 (OMIM: 608165) PTB domain-containing eng ( 304) 2054 326.3 4.6e-89 XP_016859795 (OMIM: 608165) PREDICTED: PTB domain- ( 304) 2054 326.3 4.6e-89 NP_001239597 (OMIM: 608165) PTB domain-containing ( 291) 1890 301.1 1.7e-81 XP_006712652 (OMIM: 608165) PREDICTED: PTB domain- ( 322) 1890 301.2 1.8e-81 XP_016859793 (OMIM: 608165) PREDICTED: PTB domain- ( 366) 1348 218.0 2.3e-56 XP_016859794 (OMIM: 608165) PREDICTED: PTB domain- ( 366) 1348 218.0 2.3e-56 XP_016859792 (OMIM: 608165) PREDICTED: PTB domain- ( 366) 1348 218.0 2.3e-56 XP_011509631 (OMIM: 608165) PREDICTED: PTB domain- ( 376) 1348 218.0 2.4e-56 XP_006712648 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 1348 218.0 2.4e-56 XP_006712645 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 1348 218.0 2.4e-56 XP_006712646 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 1348 218.0 2.4e-56 XP_006712647 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 1348 218.0 2.4e-56 XP_006712644 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 1348 218.0 2.4e-56 XP_006712643 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 1348 218.0 2.4e-56 XP_016859797 (OMIM: 608165) PREDICTED: PTB domain- ( 258) 1155 188.3 1.4e-47 NP_001239598 (OMIM: 608165) PTB domain-containing ( 201) 1152 187.7 1.6e-47 XP_011509634 (OMIM: 608165) PREDICTED: PTB domain- ( 351) 1140 186.0 9.1e-47 XP_011509633 (OMIM: 608165) PREDICTED: PTB domain- ( 366) 1138 185.7 1.2e-46 XP_011509637 (OMIM: 608165) PREDICTED: PTB domain- ( 276) 991 163.1 5.8e-40 XP_016859796 (OMIM: 608165) PREDICTED: PTB domain- ( 276) 991 163.1 5.8e-40 XP_011509635 (OMIM: 608165) PREDICTED: PTB domain- ( 333) 726 122.4 1.2e-27 NP_001191010 (OMIM: 607815) ankyrin repeat and ste ( 254) 306 57.9 2.5e-08 XP_005269089 (OMIM: 607815) PREDICTED: ankyrin rep ( 266) 306 57.9 2.5e-08 NP_001191009 (OMIM: 607815) ankyrin repeat and ste ( 266) 306 57.9 2.5e-08 NP_001191008 (OMIM: 607815) ankyrin repeat and ste ( 290) 306 57.9 2.7e-08 NP_001190994 (OMIM: 607815) ankyrin repeat and ste ( 290) 306 57.9 2.7e-08 NP_001190995 (OMIM: 607815) ankyrin repeat and ste ( 357) 306 58.0 3.3e-08 NP_001190996 (OMIM: 607815) ankyrin repeat and ste ( 394) 306 58.0 3.5e-08 NP_064525 (OMIM: 607815) ankyrin repeat and steril ( 414) 306 58.0 3.7e-08 XP_016875154 (OMIM: 607815) PREDICTED: ankyrin rep ( 425) 306 58.0 3.8e-08 NP_001190999 (OMIM: 607815) ankyrin repeat and ste ( 426) 306 58.0 3.8e-08 XP_016875153 (OMIM: 607815) PREDICTED: ankyrin rep ( 429) 306 58.0 3.8e-08 NP_001190998 (OMIM: 607815) ankyrin repeat and ste ( 450) 306 58.0 3.9e-08 NP_001190997 (OMIM: 607815) ankyrin repeat and ste ( 460) 306 58.0 4e-08 XP_016875152 (OMIM: 607815) PREDICTED: ankyrin rep ( 476) 306 58.1 4.1e-08 XP_016875151 (OMIM: 607815) PREDICTED: ankyrin rep ( 479) 306 58.1 4.2e-08 XP_016875150 (OMIM: 607815) PREDICTED: ankyrin rep ( 479) 306 58.1 4.2e-08 XP_016875149 (OMIM: 607815) PREDICTED: ankyrin rep ( 486) 306 58.1 4.2e-08 NP_858056 (OMIM: 607815) ankyrin repeat and steril ( 510) 306 58.1 4.4e-08 XP_016875148 (OMIM: 607815) PREDICTED: ankyrin rep ( 511) 306 58.1 4.4e-08 XP_006719577 (OMIM: 607815) PREDICTED: ankyrin rep (1184) 306 58.3 8.8e-08 XP_016875147 (OMIM: 607815) PREDICTED: ankyrin rep (1188) 306 58.3 8.9e-08 XP_006719576 (OMIM: 607815) PREDICTED: ankyrin rep (1199) 306 58.3 8.9e-08 XP_006719575 (OMIM: 607815) PREDICTED: ankyrin rep (1200) 306 58.3 8.9e-08 XP_016875146 (OMIM: 607815) PREDICTED: ankyrin rep (1226) 306 58.3 9.1e-08 XP_006719573 (OMIM: 607815) PREDICTED: ankyrin rep (1235) 306 58.3 9.1e-08 NP_690001 (OMIM: 607815) ankyrin repeat and steril (1248) 306 58.3 9.2e-08 XP_016875145 (OMIM: 607815) PREDICTED: ankyrin rep (1250) 306 58.3 9.2e-08 XP_011536873 (OMIM: 607815) PREDICTED: ankyrin rep (1251) 306 58.3 9.2e-08 XP_005269086 (OMIM: 607815) PREDICTED: ankyrin rep (1256) 306 58.3 9.3e-08 >>NP_057399 (OMIM: 608165) PTB domain-containing engulfm (304 aa) initn: 2054 init1: 2054 opt: 2054 Z-score: 1719.9 bits: 326.3 E(85289): 4.6e-89 Smith-Waterman score: 2054; 100.0% identity (100.0% similar) in 304 aa overlap (1-304:1-304) 10 20 30 40 50 60 pF1KB6 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MELKNKVQDLENQLRITQVSAPPAGSMTPKSPSTDIFDMIPFSPISHQSSMPTRNGTQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MELKNKVQDLENQLRITQVSAPPAGSMTPKSPSTDIFDMIPFSPISHQSSMPTRNGTQPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPL 250 260 270 280 290 300 pF1KB6 DSRC :::: NP_057 DSRC >>XP_016859795 (OMIM: 608165) PREDICTED: PTB domain-cont (304 aa) initn: 2054 init1: 2054 opt: 2054 Z-score: 1719.9 bits: 326.3 E(85289): 4.6e-89 Smith-Waterman score: 2054; 100.0% identity (100.0% similar) in 304 aa overlap (1-304:1-304) 10 20 30 40 50 60 pF1KB6 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MELKNKVQDLENQLRITQVSAPPAGSMTPKSPSTDIFDMIPFSPISHQSSMPTRNGTQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MELKNKVQDLENQLRITQVSAPPAGSMTPKSPSTDIFDMIPFSPISHQSSMPTRNGTQPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPL 250 260 270 280 290 300 pF1KB6 DSRC :::: XP_016 DSRC >>NP_001239597 (OMIM: 608165) PTB domain-containing engu (291 aa) initn: 1890 init1: 1890 opt: 1890 Z-score: 1584.1 bits: 301.1 E(85289): 1.7e-81 Smith-Waterman score: 1890; 100.0% identity (100.0% similar) in 281 aa overlap (1-281:1-281) 10 20 30 40 50 60 pF1KB6 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MELKNKVQDLENQLRITQVSAPPAGSMTPKSPSTDIFDMIPFSPISHQSSMPTRNGTQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELKNKVQDLENQLRITQVSAPPAGSMTPKSPSTDIFDMIPFSPISHQSSMPTRNGTQPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPL ::::::::::::::::::::::::::::::::::::::::: NP_001 PVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQRQRWRGSKWD 250 260 270 280 290 pF1KB6 DSRC >>XP_006712652 (OMIM: 608165) PREDICTED: PTB domain-cont (322 aa) initn: 1890 init1: 1890 opt: 1890 Z-score: 1583.5 bits: 301.2 E(85289): 1.8e-81 Smith-Waterman score: 1890; 100.0% identity (100.0% similar) in 281 aa overlap (1-281:1-281) 10 20 30 40 50 60 pF1KB6 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MELKNKVQDLENQLRITQVSAPPAGSMTPKSPSTDIFDMIPFSPISHQSSMPTRNGTQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MELKNKVQDLENQLRITQVSAPPAGSMTPKSPSTDIFDMIPFSPISHQSSMPTRNGTQPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPL ::::::::::::::::::::::::::::::::::::::::: XP_006 PVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQVTILIDWPINDLFHFDMGQ 250 260 270 280 290 300 pF1KB6 DSRC XP_006 RECYVPKLWFPSIIFAIKTRLK 310 320 >>XP_016859793 (OMIM: 608165) PREDICTED: PTB domain-cont (366 aa) initn: 1370 init1: 1339 opt: 1348 Z-score: 1132.9 bits: 218.0 E(85289): 2.3e-56 Smith-Waterman score: 1584; 77.7% identity (77.7% similar) in 336 aa overlap (1-261:1-336) 10 20 30 40 50 60 pF1KB6 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN 130 140 150 160 170 180 190 200 pF1KB6 MELKNKVQDLENQLRITQVSAPP------------------------------------- ::::::::::::::::::::::: XP_016 MELKNKVQDLENQLRITQVSAPPLLHNMSDHEQHVFQRCSSSFWRSNGDSSPCLNISSIS 190 200 210 220 230 240 210 220 pF1KB6 --------------------------------------AGSMTPKSPSTDIFDMIPFSPI :::::::::::::::::::::: XP_016 VTPINSPDSRLSLGLLIPPPSKCGFPKPVSESSIPRPHAGSMTPKSPSTDIFDMIPFSPI 250 260 270 280 290 300 230 240 250 260 270 280 pF1KB6 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFK :::::::::::::::::::::::::::::::::::: XP_016 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQRQRW 310 320 330 340 350 360 290 300 pF1KB6 MGLTLEGTVFCLDPLDSRC XP_016 RGSKWD >>XP_016859794 (OMIM: 608165) PREDICTED: PTB domain-cont (366 aa) initn: 1370 init1: 1339 opt: 1348 Z-score: 1132.9 bits: 218.0 E(85289): 2.3e-56 Smith-Waterman score: 1584; 77.7% identity (77.7% similar) in 336 aa overlap (1-261:1-336) 10 20 30 40 50 60 pF1KB6 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN 130 140 150 160 170 180 190 200 pF1KB6 MELKNKVQDLENQLRITQVSAPP------------------------------------- ::::::::::::::::::::::: XP_016 MELKNKVQDLENQLRITQVSAPPLLHNMSDHEQHVFQRCSSSFWRSNGDSSPCLNISSIS 190 200 210 220 230 240 210 220 pF1KB6 --------------------------------------AGSMTPKSPSTDIFDMIPFSPI :::::::::::::::::::::: XP_016 VTPINSPDSRLSLGLLIPPPSKCGFPKPVSESSIPRPHAGSMTPKSPSTDIFDMIPFSPI 250 260 270 280 290 300 230 240 250 260 270 280 pF1KB6 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFK :::::::::::::::::::::::::::::::::::: XP_016 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQRQRW 310 320 330 340 350 360 290 300 pF1KB6 MGLTLEGTVFCLDPLDSRC XP_016 RGSKWD >>XP_016859792 (OMIM: 608165) PREDICTED: PTB domain-cont (366 aa) initn: 1370 init1: 1339 opt: 1348 Z-score: 1132.9 bits: 218.0 E(85289): 2.3e-56 Smith-Waterman score: 1584; 77.7% identity (77.7% similar) in 336 aa overlap (1-261:1-336) 10 20 30 40 50 60 pF1KB6 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN 130 140 150 160 170 180 190 200 pF1KB6 MELKNKVQDLENQLRITQVSAPP------------------------------------- ::::::::::::::::::::::: XP_016 MELKNKVQDLENQLRITQVSAPPLLHNMSDHEQHVFQRCSSSFWRSNGDSSPCLNISSIS 190 200 210 220 230 240 210 220 pF1KB6 --------------------------------------AGSMTPKSPSTDIFDMIPFSPI :::::::::::::::::::::: XP_016 VTPINSPDSRLSLGLLIPPPSKCGFPKPVSESSIPRPHAGSMTPKSPSTDIFDMIPFSPI 250 260 270 280 290 300 230 240 250 260 270 280 pF1KB6 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFK :::::::::::::::::::::::::::::::::::: XP_016 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQRQRW 310 320 330 340 350 360 290 300 pF1KB6 MGLTLEGTVFCLDPLDSRC XP_016 RGSKWD >>XP_011509631 (OMIM: 608165) PREDICTED: PTB domain-cont (376 aa) initn: 1370 init1: 1339 opt: 1348 Z-score: 1132.7 bits: 218.0 E(85289): 2.4e-56 Smith-Waterman score: 1584; 77.7% identity (77.7% similar) in 336 aa overlap (1-261:1-336) 10 20 30 40 50 60 pF1KB6 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN 130 140 150 160 170 180 190 200 pF1KB6 MELKNKVQDLENQLRITQVSAPP------------------------------------- ::::::::::::::::::::::: XP_011 MELKNKVQDLENQLRITQVSAPPLLHNMSDHEQHVFQRCSSSFWRSNGDSSPCLNISSIS 190 200 210 220 230 240 210 220 pF1KB6 --------------------------------------AGSMTPKSPSTDIFDMIPFSPI :::::::::::::::::::::: XP_011 VTPINSPDSRLSLGLLIPPPSKCGFPKPVSESSIPRPHAGSMTPKSPSTDIFDMIPFSPI 250 260 270 280 290 300 230 240 250 260 270 280 pF1KB6 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFK :::::::::::::::::::::::::::::::::::: XP_011 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQFIYG 310 320 330 340 350 360 290 300 pF1KB6 MGLTLEGTVFCLDPLDSRC XP_011 RIQTDTNYMKLIEKRQ 370 >>XP_006712648 (OMIM: 608165) PREDICTED: PTB domain-cont (379 aa) initn: 1370 init1: 1339 opt: 1348 Z-score: 1132.7 bits: 218.0 E(85289): 2.4e-56 Smith-Waterman score: 1584; 77.7% identity (77.7% similar) in 336 aa overlap (1-261:1-336) 10 20 30 40 50 60 pF1KB6 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN 130 140 150 160 170 180 190 200 pF1KB6 MELKNKVQDLENQLRITQVSAPP------------------------------------- ::::::::::::::::::::::: XP_006 MELKNKVQDLENQLRITQVSAPPLLHNMSDHEQHVFQRCSSSFWRSNGDSSPCLNISSIS 190 200 210 220 230 240 210 220 pF1KB6 --------------------------------------AGSMTPKSPSTDIFDMIPFSPI :::::::::::::::::::::: XP_006 VTPINSPDSRLSLGLLIPPPSKCGFPKPVSESSIPRPHAGSMTPKSPSTDIFDMIPFSPI 250 260 270 280 290 300 230 240 250 260 270 280 pF1KB6 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFK :::::::::::::::::::::::::::::::::::: XP_006 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFK 310 320 330 340 350 360 290 300 pF1KB6 MGLTLEGTVFCLDPLDSRC XP_006 MGLTLEGTVFCLDPLDSRC 370 >-- initn: 310 init1: 310 opt: 310 Z-score: 271.4 bits: 58.6 E(85289): 2.2e-08 Smith-Waterman score: 310; 100.0% identity (100.0% similar) in 43 aa overlap (262-304:337-379) 240 250 260 270 280 290 pF1KB6 PTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLE :::::::::::::::::::::::::::::: XP_006 PTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLE 310 320 330 340 350 360 300 pF1KB6 GTVFCLDPLDSRC ::::::::::::: XP_006 GTVFCLDPLDSRC 370 >>XP_006712645 (OMIM: 608165) PREDICTED: PTB domain-cont (379 aa) initn: 1370 init1: 1339 opt: 1348 Z-score: 1132.7 bits: 218.0 E(85289): 2.4e-56 Smith-Waterman score: 1584; 77.7% identity (77.7% similar) in 336 aa overlap (1-261:1-336) 10 20 30 40 50 60 pF1KB6 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETEN 130 140 150 160 170 180 190 200 pF1KB6 MELKNKVQDLENQLRITQVSAPP------------------------------------- ::::::::::::::::::::::: XP_006 MELKNKVQDLENQLRITQVSAPPLLHNMSDHEQHVFQRCSSSFWRSNGDSSPCLNISSIS 190 200 210 220 230 240 210 220 pF1KB6 --------------------------------------AGSMTPKSPSTDIFDMIPFSPI :::::::::::::::::::::: XP_006 VTPINSPDSRLSLGLLIPPPSKCGFPKPVSESSIPRPHAGSMTPKSPSTDIFDMIPFSPI 250 260 270 280 290 300 230 240 250 260 270 280 pF1KB6 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFK :::::::::::::::::::::::::::::::::::: XP_006 SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFK 310 320 330 340 350 360 290 300 pF1KB6 MGLTLEGTVFCLDPLDSRC XP_006 MGLTLEGTVFCLDPLDSRC 370 >-- initn: 310 init1: 310 opt: 310 Z-score: 271.4 bits: 58.6 E(85289): 2.2e-08 Smith-Waterman score: 310; 100.0% identity (100.0% similar) in 43 aa overlap (262-304:337-379) 240 250 260 270 280 290 pF1KB6 PTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLE :::::::::::::::::::::::::::::: XP_006 PTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLE 310 320 330 340 350 360 300 pF1KB6 GTVFCLDPLDSRC ::::::::::::: XP_006 GTVFCLDPLDSRC 370 304 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:48:42 2016 done: Fri Nov 4 20:48:43 2016 Total Scan time: 5.640 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]