FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6402, 333 aa 1>>>pF1KB6402 333 - 333 aa - 333 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4280+/-0.000924; mu= 15.2131+/- 0.055 mean_var=67.2782+/-13.301, 0's: 0 Z-trim(105.5): 25 B-trim: 0 in 0/50 Lambda= 0.156364 statistics sampled from 8463 (8481) to 8463 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.261), width: 16 Scan time: 2.110 The best scores are: opt bits E(32554) CCDS6675.1 CTSL gene_id:1514|Hs108|chr9 ( 333) 2321 532.6 1.7e-151 CCDS6723.1 CTSV gene_id:1515|Hs108|chr9 ( 334) 1836 423.2 1.5e-118 CCDS969.1 CTSK gene_id:1513|Hs108|chr1 ( 329) 1131 264.1 1.1e-70 CCDS968.1 CTSS gene_id:1520|Hs108|chr1 ( 331) 1101 257.4 1.2e-68 CCDS55634.1 CTSS gene_id:1520|Hs108|chr1 ( 281) 796 188.5 5.4e-48 CCDS10308.1 CTSH gene_id:1512|Hs108|chr15 ( 335) 796 188.6 6.3e-48 CCDS8144.1 CTSF gene_id:8722|Hs108|chr11 ( 484) 664 158.9 7.9e-39 CCDS3794.1 CTSO gene_id:1519|Hs108|chr4 ( 321) 484 118.2 9.3e-27 CCDS8117.1 CTSW gene_id:1521|Hs108|chr11 ( 376) 395 98.1 1.2e-20 CCDS8282.1 CTSC gene_id:1075|Hs108|chr11 ( 463) 386 96.1 5.8e-20 CCDS13474.1 CTSZ gene_id:1522|Hs108|chr20 ( 303) 305 77.8 1.3e-14 >>CCDS6675.1 CTSL gene_id:1514|Hs108|chr9 (333 aa) initn: 2321 init1: 2321 opt: 2321 Z-score: 2833.2 bits: 532.6 E(32554): 1.7e-151 Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333) 10 20 30 40 50 60 pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN 250 260 270 280 290 300 310 320 330 pF1KB6 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV ::::::::::::::::::::::::::::::::: CCDS66 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 310 320 330 >>CCDS6723.1 CTSV gene_id:1515|Hs108|chr9 (334 aa) initn: 1824 init1: 1251 opt: 1836 Z-score: 2241.9 bits: 423.2 E(32554): 1.5e-118 Smith-Waterman score: 1836; 77.2% identity (91.0% similar) in 334 aa overlap (1-333:1-334) 10 20 30 40 50 60 pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE :: .:.:::::::::::. ::..:...: .::: : :::: :::::::::::::::::: CCDS67 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW ::: :: .:::.::::::::::::.:::::.:. :.:.: ::::::.:::: . :.:::: CCDS67 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG :.:::::::::: :::::::::::::::::::::::.:.::::::::::: ::::.:::: CCDS67 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQEKALMKAV :.: :::::..:::::::::::: :..: ::: :. ::::::::. . : .:::::::: CCDS67 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK :::::::::.:::: :: ::: ::::::::::...::::::::::::...:.:.:::::: CCDS67 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 250 260 270 280 290 300 300 310 320 330 pF1KB6 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV :::: ::: .::::.:::. ::::::.:::::.: CCDS67 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 310 320 330 >>CCDS969.1 CTSK gene_id:1513|Hs108|chr1 (329 aa) initn: 887 init1: 321 opt: 1131 Z-score: 1382.5 bits: 264.1 E(32554): 1.1e-70 Smith-Waterman score: 1131; 50.9% identity (76.7% similar) in 330 aa overlap (7-331:4-327) 10 20 30 40 50 pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMI : .. : ..: .: .. :...: :: : . :. . .: :: .::::.:.: CCDS96 MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYI 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQN--RKPRKGKVFQEPLFY-EAPR .:: : : :.. .::: .::::::: : :.:.. . :.. .. : . .:: CCDS96 SIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 SVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE :::.:.::::::::::::::::::::..::::::. .:::.:..:: :::::: . :. CCDS96 SVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--ND 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKAL ::.:: : :::::: : :.:::..::: . :::: ::: ..:. :. .::. .:::: CCDS96 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 MKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKY .::: :::.::::::. :: ::..:.:.. .:.:....:.::.::::... .::. CCDS96 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK----GNKH 240 250 260 270 280 290 300 310 320 330 pF1KB6 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV :..::::::.:: ::. ::... : ::::. ::.: CCDS96 WIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 300 310 320 >>CCDS968.1 CTSS gene_id:1520|Hs108|chr1 (331 aa) initn: 937 init1: 293 opt: 1101 Z-score: 1345.8 bits: 257.4 E(32554): 1.2e-68 Smith-Waterman score: 1101; 49.7% identity (75.6% similar) in 328 aa overlap (15-333:14-331) 10 20 30 40 50 pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGM-NEEGWRRAVWEKNMKMI : : : : .:. .: :: ... : :::. :: .::::.:.. CCDS96 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFV 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA----- ::: :. : ::. ..:: .::::::: ..:... : : . .:. . :.. CCDS96 MLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSL--RVPSQ---WQRNITYKSNPNRI 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 -PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ : :::::::: :: :: ::.::.::::::.::::.:. :::.:.::: ::::::: . CCDS96 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 -GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-Q ::.:::::.: ::::. :: :.::. ::::.: ...:.:. :: .:. . ....: . CCDS96 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD : .: .:::. ::.::..:: : ::..:. :.:.::.:. ....::::::::: . . CCDS96 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVGYG----DLN 240 250 260 270 280 300 310 320 330 pF1KB6 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV ...:::::::::...: ::..::... ::::::: ::: . CCDS96 GKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 290 300 310 320 330 >>CCDS55634.1 CTSS gene_id:1520|Hs108|chr1 (281 aa) initn: 643 init1: 273 opt: 796 Z-score: 975.1 bits: 188.5 E(32554): 5.4e-48 Smith-Waterman score: 895; 43.5% identity (66.5% similar) in 322 aa overlap (15-333:14-281) 10 20 30 40 50 pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGM-NEEGWRRAVWEKNMKMI : : : : .:. .: :: ... : :::. :: .::::.:.. CCDS55 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFV 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVD ::: :. : ::. ..:: .::: CCDS55 MLHNLEHSMGMHSYDLGMNHLGDM------------------------------------ 60 70 80 120 130 140 150 160 170 pF1KB6 WREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ-GNEGC :.::.::::::.::::.:. :::.:.::: ::::::: . ::.:: CCDS55 -------------GSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC 90 100 110 120 130 180 190 200 210 220 230 pF1KB6 NGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMK :::.: ::::. :: :.::. ::::.: ...:.:. :: .:. . ....: .: .: . CCDS55 NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE 140 150 160 170 180 190 240 250 260 270 280 290 pF1KB6 AVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWL :::. ::.::..:: : ::..:. :.:.::.:. ....::::::::: . ....::: CCDS55 AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVGYG----DLNGKEYWL 200 210 220 230 240 300 310 320 330 pF1KB6 VKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV ::::::...: ::..::... ::::::: ::: . CCDS55 VKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 250 260 270 280 >>CCDS10308.1 CTSH gene_id:1512|Hs108|chr15 (335 aa) initn: 576 init1: 379 opt: 796 Z-score: 973.9 bits: 188.6 E(32554): 6.3e-48 Smith-Waterman score: 796; 39.4% identity (68.2% similar) in 343 aa overlap (3-331:6-331) 10 20 30 40 50 pF1KB6 MNPTLILAAFCLGI---ASATLTFDHSLEA-QWTKWKAMHNRLYGMNEEGWRRAVWE : : .:. ::. ..: : . ::: .. .: . : . :. .: : .. CCDS10 MWATLPLLCAGAWLLGVPVCGAAELCVN-SLEKFHFKSWMSKHRKTYSTEEYHHRLQTFA 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQ--VMNGFQNRKPRKGKVFQEPLF .: . :. ::. :.:.: ::.: :.::. :... . . :: . :.. .. CCDS10 SNWRKINAHNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 YEAPRSVDWREKG-YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCS : : :::::.:: .:.:::::: :::::.::.:::::. . ::...::.::.::::. CCDS10 Y--PPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCA 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 GPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFV-DIP .:.::.::: . ::.:. : :. .:..:::.. . ::..: .. ::: :. CCDS10 QDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAI----GFVKDVA 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 K----QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGY . .:.:...::: .:.: :... .. :..:. ::: .: . . ..:.::.::: CCDS10 NITIYDEEAMVEAVALYNPVSFAFEVTQD-FMMYRTGIYSSTSCHKTPDKVNHAVLAVGY 230 240 250 260 270 280 290 300 310 320 330 pF1KB6 GFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV : :... ::.:::::: .:::.:: . . . : ::.:. :::: CCDS10 G----EKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAACASYPIPLV 290 300 310 320 330 >>CCDS8144.1 CTSF gene_id:8722|Hs108|chr11 (484 aa) initn: 632 init1: 264 opt: 664 Z-score: 810.6 bits: 158.9 E(32554): 7.9e-39 Smith-Waterman score: 664; 38.4% identity (65.6% similar) in 302 aa overlap (36-333:194-483) 10 20 30 40 50 60 pF1KB6 ILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEG-WRRAVWEKNMKMIELHNQ .:: : .::. :: .:. .:: . . : CCDS81 SSVISLLNEDPLSQDLPVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQ-KIQ 170 180 190 200 210 220 70 80 90 100 110 120 pF1KB6 EYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYE-APRSVDWREK .: .. ... :.:.: :::: .. . :: .:. : . :: ::: : CCDS81 ALDRGTAQY--GVTKFSDLTEEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSK 230 240 250 260 270 280 130 140 150 160 170 180 pF1KB6 GYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLM : :: ::.::.::::::::.:: .::: : . : :.:::::.:.::. . ...: ::: CCDS81 GAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCD--KMDKACMGGLP 290 300 310 320 330 190 200 210 220 230 240 pF1KB6 DYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVG . :.. ... :::..:..: :.. .::... . . . . :.. ..:. : .: : CCDS81 SNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRG 340 350 360 370 380 390 250 260 270 280 290 300 pF1KB6 PISVAIDAGHESFLFYKEGIY--FEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNS ::::::.: .. ::..:: ..: :: .::.::.:::: .: . .: .::: CCDS81 PISVAINA--FGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRS----DVPFWAIKNS 400 410 420 430 440 450 310 320 330 pF1KB6 WGEEWGMGGYVKMAKDRRNHCGIASAASYPTV :: .:: :: . . . ::. . :: .: CCDS81 WGTDWGEKGYYYLHRGS-GACGVNTMASSAVVD 460 470 480 >>CCDS3794.1 CTSO gene_id:1519|Hs108|chr4 (321 aa) initn: 441 init1: 188 opt: 484 Z-score: 593.8 bits: 118.2 E(32554): 9.3e-27 Smith-Waterman score: 484; 35.4% identity (61.3% similar) in 274 aa overlap (68-329:61-317) 40 50 60 70 80 90 pF1KB6 RLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQN :.. .: ...: :. . :::. . . CCDS37 PTWPRSREREAAAFRESLNRHRYLNSLFPSENSTAF-YGINQFSYLFPEEFKAI---YLR 40 50 60 70 80 100 110 120 130 140 150 pF1KB6 RKPRKGKVFQEPLFYEAPR-----SVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMF :: : .. . . : :::.: :: :.:: .::.:::::..::.:. . CCDS37 SKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYA 90 100 110 120 130 140 160 170 180 190 200 210 pF1KB6 RKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNG-GLDSEESYPYEATEESC : : .:: :...::: .: ::::: :..... : .. ::..: . : CCDS37 IKGKPLEDLSVQQVIDCS--YNNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLC 150 160 170 180 190 200 220 230 240 250 260 pF1KB6 KY----NPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEP .: . .:. . ... :. :: . ::. : ::. : .:: :. : :: .. CCDS37 HYFSGSHSGFSIKGYSAY-DFSDQEDEMAKALLTFGPLVVIVDA--VSWQDYLGGI-IQH 210 220 230 240 250 260 270 280 290 300 310 320 pF1KB6 DCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGY--VKMAKDRRNHCGIA ::: . .:.::.. ::..: : . ::.:.:::: ::. :: :::.. : :::: CCDS37 HCSSGEANHAVLIT--GFDKTGS--TPYWIVRNSWGSSWGVDGYAHVKMGS---NVCGIA 270 280 290 300 310 330 pF1KB6 SAASYPTV ...: CCDS37 DSVSSIFV 320 >>CCDS8117.1 CTSW gene_id:1521|Hs108|chr11 (376 aa) initn: 367 init1: 174 opt: 395 Z-score: 484.3 bits: 98.1 E(32554): 1.2e-20 Smith-Waterman score: 477; 30.7% identity (59.8% similar) in 326 aa overlap (25-324:38-354) 10 20 30 40 50 pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRA-VWE :. . .. . :: : :: .: .. CCDS81 SCLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFA 10 20 30 40 50 60 60 70 80 90 100 pF1KB6 KNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRK---PRKGK-VFQEP .:. . . . :: : : ... :.:.: ::: : . :.. : :. . .: CCDS81 HNLAQAQ-RLQEEDLGTAEF--GVTPFSDLTEEEFGQ-LYGYRRAAGGVPSMGREIRSEE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 LFYEAPRSVDWRE-KGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVD .: : :::. . ..:.:.: .:. :::..:.: .: . ....: :.:.: CCDS81 PEESVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLD 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 CSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPK--YSVANDTGFV : : :. ::.::.. :: : .:.:: ::..::... .. . .:: .:: :. CCDS81 C-GRCGD-GCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDFI 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB6 DIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIY-FEPD-CSSEDMDHGVLVVGYG . ..:. . . .:: :::.:.:. . . .:..:. : :. . .::.::.::.: CCDS81 MLQNNEHRIAQYLATYGPITVTINM--KPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFG 250 260 270 280 290 290 300 310 320 pF1KB6 FESTE--------SDNNK--------YWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAA ..: :.... ::..::::: .:: :: .. . : ::: CCDS81 SVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGS-NTCGITKFP 300 310 320 330 340 350 330 pF1KB6 SYPTV CCDS81 LTARVQKPDMKPRVSCPP 360 370 >>CCDS8282.1 CTSC gene_id:1075|Hs108|chr11 (463 aa) initn: 341 init1: 165 opt: 386 Z-score: 471.9 bits: 96.1 E(32554): 5.8e-20 Smith-Waterman score: 436; 31.4% identity (59.0% similar) in 334 aa overlap (32-328:134-454) 10 20 30 40 50 60 pF1KB6 NPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIEL : . .. : :. . . . .. . CCDS82 FFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGTASENVYVNIAHLKNSQEKY 110 120 130 140 150 160 70 80 90 100 pF1KB6 HNQEYREGKHSFTMAMNAFGD----MTSEEFRQVM-------NGFQNRK-PRKGKV---- :. :. :.:. :.::. : :.. . .: ..:: :: . CCDS82 SNRLYKYD-HNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTA 170 180 190 200 210 220 110 120 130 140 150 pF1KB6 -FQEPLFYEAPRSVDWRE-KG--YVTPVKNQGQCGSCWAFSATGALEGQM--FRKTGRLI .:. ... : : :::. .: .:.::.::..::::..:.. : ::... . .... CCDS82 EIQQKILH-LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTP 230 240 250 260 270 280 160 170 180 190 200 210 pF1KB6 SLSEQNLVDCSGPQGNEGCNGGL-MDYAFQYVQDNGGLDSEESYPYEATEESCK------ :: :..:.:: : .::.::. . : .:.:: : : : .:: .:. :: CCDS82 ILSPQEVVSCS--QYAQGCEGGFPYLIAGKYAQDFG-LVEEACFPYTGTDSPCKMKEDCF 290 300 310 320 330 220 230 240 250 260 pF1KB6 --YNPKYSVANDTGFVDIPKQEKALMK-AVATVGPISVAIDAGHESFLFYKEGIYF---- :. .: .. :: ..:::: .. ::..::... ...:: ::.::: CCDS82 RYYSSEYHYVG--GFYG--GCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTGL 340 350 360 370 380 390 270 280 290 300 310 320 pF1KB6 -EPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI .: : .:.::.:::: .: ... ::.:::::: :: .:: .. . ..:.: CCDS82 RDPFNPFELTNHAVLLVGYGTDS--ASGMDYWIVKNSWGTGWGENGYFRIRRGT-DECAI 400 410 420 430 440 450 330 pF1KB6 ASAASYPTV : : CCDS82 ESIAVAATPIPKL 460 333 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:49:15 2016 done: Fri Nov 4 20:49:15 2016 Total Scan time: 2.110 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]