FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6403, 304 aa 1>>>pF1KB6403 304 - 304 aa - 304 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8064+/-0.000362; mu= 14.5692+/- 0.023 mean_var=89.8515+/-19.024, 0's: 0 Z-trim(114.6): 167 B-trim: 2571 in 2/50 Lambda= 0.135304 statistics sampled from 24308 (24494) to 24308 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.287), width: 16 Scan time: 7.130 The best scores are: opt bits E(85289) NP_003012 (OMIM: 603419) small glutamine-rich tetr ( 313) 1123 229.0 9.2e-60 XP_011526480 (OMIM: 603419) PREDICTED: small gluta ( 313) 1123 229.0 9.2e-60 NP_001139547 (OMIM: 611477) RNA polymerase II-asso ( 631) 307 70.0 1.4e-11 NP_078880 (OMIM: 611477) RNA polymerase II-associa ( 665) 307 70.0 1.5e-11 NP_006810 (OMIM: 605063) stress-induced-phosphopro ( 543) 285 65.6 2.5e-10 NP_001269581 (OMIM: 605063) stress-induced-phospho ( 590) 283 65.3 3.5e-10 NP_001139548 (OMIM: 611477) RNA polymerase II-asso ( 506) 274 63.4 1e-09 NP_001191213 (OMIM: 600658) serine/threonine-prote ( 477) 266 61.9 2.9e-09 NP_006238 (OMIM: 600658) serine/threonine-protein ( 499) 266 61.9 3e-09 XP_016882424 (OMIM: 600658) PREDICTED: serine/thre ( 551) 266 61.9 3.3e-09 XP_011523470 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 261 60.9 5.4e-09 NP_001138238 (OMIM: 601964) dnaJ homolog subfamily ( 438) 261 60.9 5.4e-09 XP_016880483 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 261 60.9 5.4e-09 XP_011523471 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 261 60.9 5.4e-09 XP_011523469 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 261 60.9 5.4e-09 NP_001269582 (OMIM: 605063) stress-induced-phospho ( 519) 249 58.6 3.1e-08 NP_060338 (OMIM: 610732) tetratricopeptide repeat ( 705) 248 58.5 4.6e-08 XP_016873439 (OMIM: 610732) PREDICTED: tetratricop ( 753) 248 58.5 4.8e-08 XP_016873438 (OMIM: 610732) PREDICTED: tetratricop ( 755) 248 58.5 4.8e-08 XP_016873437 (OMIM: 610732) PREDICTED: tetratricop ( 760) 248 58.5 4.8e-08 XP_016873436 (OMIM: 610732) PREDICTED: tetratricop ( 774) 248 58.5 4.9e-08 XP_016873435 (OMIM: 610732) PREDICTED: tetratricop ( 777) 248 58.5 4.9e-08 XP_016873434 (OMIM: 610732) PREDICTED: tetratricop ( 777) 248 58.5 4.9e-08 XP_016873432 (OMIM: 610732) PREDICTED: tetratricop ( 777) 248 58.5 4.9e-08 XP_005271661 (OMIM: 610732) PREDICTED: tetratricop ( 777) 248 58.5 4.9e-08 XP_016873433 (OMIM: 610732) PREDICTED: tetratricop ( 777) 248 58.5 4.9e-08 NP_005852 (OMIM: 607207,615768) E3 ubiquitin-prote ( 303) 241 56.8 6.1e-08 NP_003306 (OMIM: 601964) dnaJ homolog subfamily C ( 494) 238 56.4 1.3e-07 XP_005260311 (OMIM: 616049) PREDICTED: mitochondri ( 207) 219 52.4 8.8e-07 NP_001305462 (OMIM: 610732) tetratricopeptide repe ( 711) 226 54.2 9e-07 NP_001295210 (OMIM: 611220,616279) protein unc-45 ( 850) 226 54.2 1e-06 XP_016879723 (OMIM: 611220,616279) PREDICTED: prot ( 850) 226 54.2 1e-06 NP_001253981 (OMIM: 611220,616279) protein unc-45 ( 929) 226 54.3 1.1e-06 NP_001028748 (OMIM: 611220,616279) protein unc-45 ( 929) 226 54.3 1.1e-06 NP_775259 (OMIM: 611220,616279) protein unc-45 hom ( 931) 226 54.3 1.1e-06 XP_011526803 (OMIM: 616049) PREDICTED: mitochondri ( 283) 219 52.5 1.1e-06 NP_006800 (OMIM: 616049) mitochondrial import rece ( 309) 219 52.6 1.2e-06 XP_011515547 (OMIM: 603395,615505) PREDICTED: sper ( 487) 220 52.9 1.5e-06 NP_001278262 (OMIM: 606753) tetratricopeptide repe ( 288) 215 51.8 2e-06 XP_011515543 (OMIM: 603395,615505) PREDICTED: sper ( 871) 220 53.1 2.4e-06 NP_004614 (OMIM: 606753) tetratricopeptide repeat ( 387) 215 51.8 2.5e-06 NP_001269429 (OMIM: 601963) tetratricopeptide repe ( 292) 207 50.2 5.9e-06 NP_003305 (OMIM: 601963) tetratricopeptide repeat ( 292) 207 50.2 5.9e-06 NP_061141 (OMIM: 611219) protein unc-45 homolog A ( 944) 213 51.7 6.5e-06 NP_001310548 (OMIM: 611219) protein unc-45 homolog ( 944) 213 51.7 6.5e-06 XP_011520081 (OMIM: 611219) PREDICTED: protein unc ( 944) 213 51.7 6.5e-06 NP_001034764 (OMIM: 611219) protein unc-45 homolog ( 929) 212 51.5 7.4e-06 NP_001310550 (OMIM: 611219) protein unc-45 homolog ( 929) 212 51.5 7.4e-06 NP_570722 (OMIM: 127700,608706,615482) dyslexia su ( 420) 207 50.3 7.8e-06 NP_055635 (OMIM: 606081) mitochondrial import rece ( 608) 204 49.8 1.6e-05 >>NP_003012 (OMIM: 603419) small glutamine-rich tetratri (313 aa) initn: 1152 init1: 736 opt: 1123 Z-score: 1193.9 bits: 229.0 E(85289): 9.2e-60 Smith-Waterman score: 1123; 58.3% identity (81.4% similar) in 312 aa overlap (1-303:1-311) 10 20 30 40 50 60 pF1KB6 MSSIKHLVYAVIRFLREQSQMDTYTSDEQESLEVAIQCLETVFKISPEDTHLAVSQPLTE :.. :.:.::.:.::..: . .:: :::::::::::::.: .. ::. ::. : : : NP_003 MDNKKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPE 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 MF----TSSFCKNDVLPLSNSVP--EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIEL .: :.. .:. . . : :: ..:..:: :::..:: ::. ::: : .:::: NP_003 IFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIEL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 DPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVT .: ::::.:::::: ::::.:. :..:::.:: :: ::::::::::::..::: :::. NP_003 NPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 SYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFISMAASLMQN :.:::.:::.:..::::::::: ::::. :::: :::.:.:.:::.:.:::..::.: NP_003 YYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNN 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 PQVQQLMSGMMT---NAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHI ::.:::::::.. : .: :... . .::.::::::::::::.::::::::::::..: NP_003 PQIQQLMSGMISGGNNPLGTPGTS-PSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQI 250 260 270 280 290 300 pF1KB6 RSRSFSSSAEEHS :::. :.: ... NP_003 RSRTPSASNDDQQE 300 310 >>XP_011526480 (OMIM: 603419) PREDICTED: small glutamine (313 aa) initn: 1152 init1: 736 opt: 1123 Z-score: 1193.9 bits: 229.0 E(85289): 9.2e-60 Smith-Waterman score: 1123; 58.3% identity (81.4% similar) in 312 aa overlap (1-303:1-311) 10 20 30 40 50 60 pF1KB6 MSSIKHLVYAVIRFLREQSQMDTYTSDEQESLEVAIQCLETVFKISPEDTHLAVSQPLTE :.. :.:.::.:.::..: . .:: :::::::::::::.: .. ::. ::. : : : XP_011 MDNKKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPE 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 MF----TSSFCKNDVLPLSNSVP--EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIEL .: :.. .:. . . : :: ..:..:: :::..:: ::. ::: : .:::: XP_011 IFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIEL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 DPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVT .: ::::.:::::: ::::.:. :..:::.:: :: ::::::::::::..::: :::. XP_011 NPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 SYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFISMAASLMQN :.:::.:::.:..::::::::: ::::. :::: :::.:.:.:::.:.:::..::.: XP_011 YYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNN 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 PQVQQLMSGMMT---NAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHI ::.:::::::.. : .: :... . .::.::::::::::::.::::::::::::..: XP_011 PQIQQLMSGMISGGNNPLGTPGTS-PSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQI 250 260 270 280 290 300 pF1KB6 RSRSFSSSAEEHS :::. :.: ... XP_011 RSRTPSASNDDQQE 300 310 >>NP_001139547 (OMIM: 611477) RNA polymerase II-associat (631 aa) initn: 350 init1: 291 opt: 307 Z-score: 328.7 bits: 70.0 E(85289): 1.4e-11 Smith-Waterman score: 307; 39.1% identity (69.9% similar) in 133 aa overlap (76-206:124-256) 50 60 70 80 90 100 pF1KB6 SPEDTHLAVSQPLTEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAV ... : :: ::..::...:. .: :. NP_001 AKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAI 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB6 DCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTA ::::.... :: : : :::.: .: ... : .::. :.:.. .:.:::.: : : : NP_001 DCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFA 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB6 LNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKL--REVSSPTGTGLSFDMASLINNPA :.:.::: .:...:.:.:.: ..:. : : .: : : NP_001 LQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQI 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB6 FISMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPEL NP_001 EAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYE 280 290 300 310 320 330 >-- initn: 291 init1: 272 opt: 286 Z-score: 306.6 bits: 65.9 E(85289): 2.4e-10 Smith-Waterman score: 286; 34.4% identity (61.4% similar) in 215 aa overlap (89-286:286-498) 60 70 80 90 100 110 pF1KB6 TEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNN ::.::. .:: .: :..:::..: : : NP_001 PKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGAN 260 270 280 290 300 310 120 130 140 150 160 170 pF1KB6 AVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQK :. ::: : :. .: .: ::: .:: .:..::::..: : : : :.:..:: ... NP_001 ALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFET 320 330 340 350 360 370 180 190 200 210 220 pF1KB6 ALDLDPENDSYKSNL-KIAEQKLREVS-SPTGTGL-SFDM------ASLINNPAFISMAA .: :.: : . ..: :: .. :..: ::. . ..:. :. ::: :..: NP_001 VLLLEPGNKQAVTELSKIKKKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNP--INLAN 380 390 400 410 420 430 230 240 250 260 270 280 pF1KB6 SLMQNPQVQQLMSGM--MTNAIGGPAAGVGGL---TDLSSLI-QAG--QQFAQQIQQQNP . . ... :.. . . : : : . .: ::: ::. :. :. ... : NP_001 VIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMP 440 450 460 470 480 490 290 300 pF1KB6 ELIEQLRNHIRSRSFSSSAEEHS ::: NP_001 IEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLD 500 510 520 530 540 550 >>NP_078880 (OMIM: 611477) RNA polymerase II-associated (665 aa) initn: 602 init1: 291 opt: 307 Z-score: 328.4 bits: 70.0 E(85289): 1.5e-11 Smith-Waterman score: 307; 39.1% identity (69.9% similar) in 133 aa overlap (76-206:124-256) 50 60 70 80 90 100 pF1KB6 SPEDTHLAVSQPLTEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAV ... : :: ::..::...:. .: :. NP_078 AKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAI 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB6 DCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTA ::::.... :: : : :::.: .: ... : .::. :.:.. .:.:::.: : : : NP_078 DCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFA 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB6 LNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKL--REVSSPTGTGLSFDMASLINNPA :.:.::: .:...:.:.:.: ..:. : : .: : : NP_078 LQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQI 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB6 FISMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPEL NP_078 EAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYE 280 290 300 310 320 330 >-- initn: 353 init1: 266 opt: 274 Z-score: 293.6 bits: 63.5 E(85289): 1.3e-09 Smith-Waterman score: 274; 41.2% identity (70.2% similar) in 114 aa overlap (89-202:286-399) 60 70 80 90 100 110 pF1KB6 TEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNN ::.::. .:: .: :..:::..: : : NP_078 PKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGAN 260 270 280 290 300 310 120 130 140 150 160 170 pF1KB6 AVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQK :. ::: : :. .: .: ::: .:: .:..::::..: : : : :.:..:: ... NP_078 ALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFET 320 330 340 350 360 370 180 190 200 210 220 230 pF1KB6 ALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFISMAASLMQNPQVQ .: :.: : . ..:. ...: : NP_078 VLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKV 380 390 400 410 420 430 >>NP_006810 (OMIM: 605063) stress-induced-phosphoprotein (543 aa) initn: 314 init1: 275 opt: 285 Z-score: 306.4 bits: 65.6 E(85289): 2.5e-10 Smith-Waterman score: 285; 32.5% identity (64.4% similar) in 160 aa overlap (84-241:3-156) 60 70 80 90 100 110 pF1KB6 VSQPLTEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIE ....::..::. .. : :..::..::. NP_006 MEQVNELKEKGNKALSVGNIDDALQCYSEAIK 10 20 30 120 130 140 150 160 170 pF1KB6 LDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAV :::.: : : ::.:: .: : : : .: :.. . ..:.:.: . :: ::.:::: NP_006 LDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAK 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB6 TSYQKALDLDPENDSYKSNLKIAEQKL--REVSSPTGTGLSFDMASLINNPAFISMAASL .:...: . .: . : .:. : .: :. .: :.: .: .. . .: NP_006 RTYEEGLKHEANNPQLKEGLQNMEARLAERKFMNP------FNMPNLYQKLESDPRTRTL 100 110 120 130 140 240 250 260 270 280 290 pF1KB6 MQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHI ...: ..:. NP_006 LSDPTYRELIEQLRNKPSDLGTKLQDPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPK 150 160 170 180 190 200 >-- initn: 282 init1: 243 opt: 249 Z-score: 268.5 bits: 58.6 E(85289): 3.2e-08 Smith-Waterman score: 249; 30.5% identity (63.0% similar) in 154 aa overlap (89-236:364-516) 60 70 80 90 100 110 pF1KB6 TEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNN :..::. ... .: :. ::.::. .:.. NP_006 DVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKD 340 350 360 370 380 390 120 130 140 150 160 170 pF1KB6 AVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQK : : :::: .:: .. :.::::. : .. . :.: : . :: :.. . .:. ::: NP_006 AKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQK 400 410 420 430 440 450 180 190 200 210 220 230 pF1KB6 ALDLDPE----NDSYKSNLKIAEQKLREVSSPTGTGLSFD--MASLINNPAFISMAASLM ::::: :.:. . .:. . .. . : . .....::. . ... NP_006 ALDLDSSCKEAADGYQRCM-MAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQ 460 470 480 490 500 510 240 250 260 270 280 290 pF1KB6 QNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIR ..:: NP_006 KDPQALSEHLKNPVIAQKIQKLMDVGLIAIR 520 530 540 >-- initn: 170 init1: 157 opt: 218 Z-score: 235.8 bits: 52.5 E(85289): 2.2e-06 Smith-Waterman score: 218; 31.4% identity (61.3% similar) in 137 aa overlap (73-202:213-348) 50 60 70 80 90 100 pF1KB6 FKISPEDTHLAVSQPLTEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYA :. ...::. .: . :. ::. .:.... NP_006 LGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFD 190 200 210 220 230 240 110 120 130 140 150 pF1KB6 AAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDS-------KYSKA .:. : .: ::::.: .: :.::. . : :. . ::::: . . .:: NP_006 TALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKA 250 260 270 280 290 300 160 170 180 190 200 210 pF1KB6 YGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDM :.:.: . .:...:. :.:.: : :. . ::. :.: NP_006 YARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQ-AEKILKEQERLAYINPDLAL 310 320 330 340 350 360 220 230 240 250 260 270 pF1KB6 ASLINNPAFISMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQ NP_006 EEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECI 370 380 390 400 410 420 >>NP_001269581 (OMIM: 605063) stress-induced-phosphoprot (590 aa) initn: 312 init1: 273 opt: 283 Z-score: 303.8 bits: 65.3 E(85289): 3.5e-10 Smith-Waterman score: 283; 32.9% identity (63.9% similar) in 158 aa overlap (86-241:52-203) 60 70 80 90 100 110 pF1KB6 QPLTEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELD ..::..::. .. : :..::..::.:: NP_001 GQRGYDWQCKRPIRVAEVRSSLHSWSLRWVNELKEKGNKALSVGNIDDALQCYSEAIKLD 30 40 50 60 70 80 120 130 140 150 160 170 pF1KB6 PNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTS :.: : : ::.:: .: : : : .: :.. . ..:.:.: . :: ::.:::: . NP_001 PHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRT 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB6 YQKALDLDPENDSYKSNLKIAEQKL--REVSSPTGTGLSFDMASLINNPAFISMAASLMQ :...: . .: . : .:. : .: :. .: :.: .: .. . .:.. NP_001 YEEGLKHEANNPQLKEGLQNMEARLAERKFMNP------FNMPNLYQKLESDPRTRTLLS 150 160 170 180 190 240 250 260 270 280 290 pF1KB6 NPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRS .: ..:. NP_001 DPTYRELIEQLRNKPSDLGTKLQDPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPKKE 200 210 220 230 240 250 >-- initn: 282 init1: 243 opt: 249 Z-score: 268.0 bits: 58.6 E(85289): 3.5e-08 Smith-Waterman score: 249; 30.5% identity (63.0% similar) in 154 aa overlap (89-236:411-563) 60 70 80 90 100 110 pF1KB6 TEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNN :..::. ... .: :. ::.::. .:.. NP_001 DVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKD 390 400 410 420 430 440 120 130 140 150 160 170 pF1KB6 AVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQK : : :::: .:: .. :.::::. : .. . :.: : . :: :.. . .:. ::: NP_001 AKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQK 450 460 470 480 490 500 180 190 200 210 220 230 pF1KB6 ALDLDPE----NDSYKSNLKIAEQKLREVSSPTGTGLSFD--MASLINNPAFISMAASLM ::::: :.:. . .:. . .. . : . .....::. . ... NP_001 ALDLDSSCKEAADGYQRCM-MAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQ 510 520 530 540 550 240 250 260 270 280 290 pF1KB6 QNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIR ..:: NP_001 KDPQALSEHLKNPVIAQKIQKLMDVGLIAIR 560 570 580 590 >-- initn: 170 init1: 157 opt: 218 Z-score: 235.3 bits: 52.6 E(85289): 2.3e-06 Smith-Waterman score: 218; 31.4% identity (61.3% similar) in 137 aa overlap (73-202:260-395) 50 60 70 80 90 100 pF1KB6 FKISPEDTHLAVSQPLTEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYA :. ...::. .: . :. ::. .:.... NP_001 LGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFD 230 240 250 260 270 280 110 120 130 140 150 pF1KB6 AAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDS-------KYSKA .:. : .: ::::.: .: :.::. . : :. . ::::: . . .:: NP_001 TALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKA 290 300 310 320 330 340 160 170 180 190 200 210 pF1KB6 YGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDM :.:.: . .:...:. :.:.: : :. . ::. :.: NP_001 YARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQ-AEKILKEQERLAYINPDLAL 350 360 370 380 390 400 220 230 240 250 260 270 pF1KB6 ASLINNPAFISMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQ NP_001 EEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECI 410 420 430 440 450 460 >>NP_001139548 (OMIM: 611477) RNA polymerase II-associat (506 aa) initn: 451 init1: 266 opt: 274 Z-score: 295.3 bits: 63.4 E(85289): 1e-09 Smith-Waterman score: 279; 32.4% identity (62.2% similar) in 185 aa overlap (30-202:56-240) 10 20 30 40 50 pF1KB6 MSSIKHLVYAVIRFLREQSQMDTYTSDEQESLEVAIQCLETVFKISPEDTHLA-----V ..:: : . : :... :.. . . . NP_001 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI 30 40 50 60 70 80 60 70 80 90 100 pF1KB6 SQPLTEMFTSSFCKNDVLPLSNS-------VPEDVGKADQLKDEGNNHMKEENYAAAVDC :: :. .: . :.. :. . .. .: . ::.::. .:: .: :..: NP_001 SQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIEC 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB6 YTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALN ::..: : ::. ::: : :. .: .: ::: .:: .:..::::..: : : : :. NP_001 YTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLG 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB6 KFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFISM :..:: ... .: :.: : . ..:. ...: : NP_001 KLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPIDNPP 210 220 230 240 250 260 230 240 250 260 270 280 pF1KB6 AASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQL NP_001 HPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDD 270 280 290 300 310 320 >>NP_001191213 (OMIM: 600658) serine/threonine-protein p (477 aa) initn: 254 init1: 254 opt: 266 Z-score: 287.2 bits: 61.9 E(85289): 2.9e-09 Smith-Waterman score: 266; 35.3% identity (64.7% similar) in 136 aa overlap (73-202:14-149) 50 60 70 80 90 100 pF1KB6 FKISPEDTHLAVSQPLTEMFTSSFCKNDVLPLSNSVPED--VGKADQLKDEGNNHMKEEN : . : : . .:..:: ..:...: .. NP_001 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKD 10 20 30 40 110 120 130 140 150 160 pF1KB6 YAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMG : :. :.:::::.:.::.:: ::. : . : :. : .:: .:.:: :.: : . NP_001 YENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRA 50 60 70 80 90 100 170 180 190 200 210 pF1KB6 LALTALNKFEEAVTSYQKALDLDPENDS----YKSNLKIAEQKLREVSSPTGTGLSFDMA . ::.::. :. .:. .. . :.. . :. ::..:: : NP_001 ASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVD 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB6 SLINNPAFISMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQI NP_001 SLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQTEKITVCGDTHG 170 180 190 200 210 220 >>NP_006238 (OMIM: 600658) serine/threonine-protein phos (499 aa) initn: 254 init1: 254 opt: 266 Z-score: 286.9 bits: 61.9 E(85289): 3e-09 Smith-Waterman score: 266; 35.3% identity (64.7% similar) in 136 aa overlap (73-202:14-149) 50 60 70 80 90 100 pF1KB6 FKISPEDTHLAVSQPLTEMFTSSFCKNDVLPLSNSVPED--VGKADQLKDEGNNHMKEEN : . : : . .:..:: ..:...: .. NP_006 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKD 10 20 30 40 110 120 130 140 150 160 pF1KB6 YAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMG : :. :.:::::.:.::.:: ::. : . : :. : .:: .:.:: :.: : . NP_006 YENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRA 50 60 70 80 90 100 170 180 190 200 210 pF1KB6 LALTALNKFEEAVTSYQKALDLDPENDS----YKSNLKIAEQKLREVSSPTGTGLSFDMA . ::.::. :. .:. .. . :.. . :. ::..:: : NP_006 ASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVD 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB6 SLINNPAFISMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQI NP_006 SLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKL 170 180 190 200 210 220 >>XP_016882424 (OMIM: 600658) PREDICTED: serine/threonin (551 aa) initn: 254 init1: 254 opt: 266 Z-score: 286.3 bits: 61.9 E(85289): 3.3e-09 Smith-Waterman score: 266; 35.3% identity (64.7% similar) in 136 aa overlap (73-202:14-149) 50 60 70 80 90 100 pF1KB6 FKISPEDTHLAVSQPLTEMFTSSFCKNDVLPLSNSVPED--VGKADQLKDEGNNHMKEEN : . : : . .:..:: ..:...: .. XP_016 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKD 10 20 30 40 110 120 130 140 150 160 pF1KB6 YAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMG : :. :.:::::.:.::.:: ::. : . : :. : .:: .:.:: :.: : . XP_016 YENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRA 50 60 70 80 90 100 170 180 190 200 210 pF1KB6 LALTALNKFEEAVTSYQKALDLDPENDS----YKSNLKIAEQKLREVSSPTGTGLSFDMA . ::.::. :. .:. .. . :.. . :. ::..:: : XP_016 ASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVD 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB6 SLINNPAFISMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQI XP_016 SLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKL 170 180 190 200 210 220 304 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:04:49 2016 done: Fri Nov 4 17:04:50 2016 Total Scan time: 7.130 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]