FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6407, 306 aa
1>>>pF1KB6407 306 - 306 aa - 306 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4890+/-0.000989; mu= 14.2189+/- 0.059
mean_var=61.4346+/-12.307, 0's: 0 Z-trim(103.2): 27 B-trim: 0 in 0/48
Lambda= 0.163632
statistics sampled from 7304 (7321) to 7304 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.225), width: 16
Scan time: 2.320
The best scores are: opt bits E(32554)
CCDS13446.1 DOK5 gene_id:55816|Hs108|chr20 ( 306) 2068 496.9 7.9e-141
CCDS32841.1 DOK6 gene_id:220164|Hs108|chr18 ( 331) 1513 365.9 2.3e-101
CCDS13447.1 DOK5 gene_id:55816|Hs108|chr20 ( 198) 1336 324.1 5.6e-89
CCDS81986.1 DOK4 gene_id:55715|Hs108|chr16 ( 365) 1243 302.2 3.9e-82
CCDS10783.1 DOK4 gene_id:55715|Hs108|chr16 ( 326) 1242 301.9 4.2e-82
>>CCDS13446.1 DOK5 gene_id:55816|Hs108|chr20 (306 aa)
initn: 2068 init1: 2068 opt: 2068 Z-score: 2641.8 bits: 496.9 E(32554): 7.9e-141
Smith-Waterman score: 2068; 100.0% identity (100.0% similar) in 306 aa overlap (1-306:1-306)
10 20 30 40 50 60
pF1KB6 MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 VKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFP
250 260 270 280 290 300
pF1KB6 AYRSEH
::::::
CCDS13 AYRSEH
>>CCDS32841.1 DOK6 gene_id:220164|Hs108|chr18 (331 aa)
initn: 1469 init1: 1469 opt: 1513 Z-score: 1933.2 bits: 365.9 E(32554): 2.3e-101
Smith-Waterman score: 1513; 70.1% identity (89.6% similar) in 308 aa overlap (1-306:1-307)
10 20 30 40 50 60
pF1KB6 MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT
::::::::::::::.::::.:::..::::::::::::::.::::: ::.::::: .::::
CCDS32 MASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS
::.:.::..:::. :::::..: :.:.:::::::::.:::.:::: : :::.:::.::::
CCDS32 ELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP
::::::::.::.:::.:::::::::.::::..:::..:::.: : :::..: .:::. ::
CCDS32 LGEPDLLAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLWDIHNAKVKLVMWP
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERL-LQ
::.:::::::.::::::.::::.:::::: ::::.:: ::::::::.:::::::::: :.
CCDS32 LSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAIAEQHERLMLE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 SVKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVS-SPLKLHRTET
... :: ...: .:: . :::::::.:::::.:.:..: :: . . :. :..:
CCDS32 MEQKARLQTSLTE-PMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQT
250 260 270 280 290
300
pF1KB6 FPAYRSEH
::.: :.
CCDS32 FPSYAPEQSEEAQQPLSRSSSYGFSYSSSLIQ
300 310 320 330
>>CCDS13447.1 DOK5 gene_id:55816|Hs108|chr20 (198 aa)
initn: 1336 init1: 1336 opt: 1336 Z-score: 1711.0 bits: 324.1 E(32554): 5.6e-89
Smith-Waterman score: 1336; 100.0% identity (100.0% similar) in 198 aa overlap (109-306:1-198)
80 90 100 110 120 130
pF1KB6 AIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDISLGEPDLLATGVEREQSER
::::::::::::::::::::::::::::::
CCDS13 MECVGTRINDISLGEPDLLATGVEREQSER
10 20 30
140 150 160 170 180 190
pF1KB6 FNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 FNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEA
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB6 GRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKMSERAASLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKMSERAASLS
100 110 120 130 140 150
260 270 280 290 300
pF1KB6 TMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFPAYRSEH
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 TMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFPAYRSEH
160 170 180 190
>>CCDS81986.1 DOK4 gene_id:55715|Hs108|chr16 (365 aa)
initn: 1238 init1: 1176 opt: 1243 Z-score: 1588.0 bits: 302.2 E(32554): 3.9e-82
Smith-Waterman score: 1243; 62.0% identity (84.9% similar) in 292 aa overlap (1-290:1-292)
10 20 30 40 50 60
pF1KB6 MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT
::.::.::::::::...::.::::.::::::.:.:::::.::::. ::... .: :::
CCDS81 MATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS
:..::: :.:::: ::..:..: :.::...::.:.:.:::.:: :.:..::.:.:.::::
CCDS81 EISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP
:::::::: ::. ::..::::.:.: :::::.::: ::::.: : :::..::::::.:::
CCDS81 LGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWP
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHER-LLQ
: .:::::::.: :::::::::..::::. :::..:: :::.::::.:::::::.: ::.
CCDS81 LCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 SVKNSMLQMKMSERAASLSTMVP-LPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTET
:: : : .:. . : . :::::::.::: ... .. : :
CCDS81 MEKNVRLLNKGTEHYSYPCTPTTMLPRSAYWHHITGSQNIAEASSYAGESLPCPTPTCQE
250 260 270 280 290 300
300
pF1KB6 FPAYRSEH
CCDS81 ALWRMRPIGQGSFDLALSSEPASVPTGEGYGAAQASSETDLLNRFILLKPKPSQGDSSEA
310 320 330 340 350 360
>>CCDS10783.1 DOK4 gene_id:55715|Hs108|chr16 (326 aa)
initn: 1238 init1: 1176 opt: 1242 Z-score: 1587.6 bits: 301.9 E(32554): 4.2e-82
Smith-Waterman score: 1242; 65.1% identity (87.6% similar) in 275 aa overlap (1-273:1-275)
10 20 30 40 50 60
pF1KB6 MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT
::.::.::::::::...::.::::.::::::.:.:::::.::::. ::... .: :::
CCDS10 MATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS
:..::: :.:::: ::..:..: :.::...::.:.:.:::.:: :.:..::.:.:.::::
CCDS10 EISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP
:::::::: ::. ::..::::.:.: :::::.::: ::::.: : :::..::::::.:::
CCDS10 LGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWP
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHER-LLQ
: .:::::::.: :::::::::..::::. :::..:: :::.::::.:::::::.: ::.
CCDS10 LCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 SVKNSMLQMKMSERAASLSTMVP-LPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTET
:: : : .:. . : . :::::::.:::
CCDS10 MEKNVRLLNKGTEHYSYPCTPTTMLPRSAYWHHITGSQNIAEASSYAGEGYGAAQASSET
250 260 270 280 290 300
300
pF1KB6 FPAYRSEH
CCDS10 DLLNRFILLKPKPSQGDSSEAKTPSQ
310 320
306 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:44:28 2016 done: Sat Nov 5 18:44:29 2016
Total Scan time: 2.320 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]