FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6408, 335 aa 1>>>pF1KB6408 335 - 335 aa - 335 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3046+/-0.000812; mu= 16.2576+/- 0.049 mean_var=73.6913+/-14.782, 0's: 0 Z-trim(108.1): 50 B-trim: 0 in 0/52 Lambda= 0.149405 statistics sampled from 9959 (10009) to 9959 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.307), width: 16 Scan time: 2.040 The best scores are: opt bits E(32554) CCDS1207.1 SLAMF1 gene_id:6504|Hs108|chr1 ( 335) 2209 485.3 3e-137 CCDS81389.1 SLAMF1 gene_id:6504|Hs108|chr1 ( 357) 1759 388.3 4.9e-108 CCDS1210.1 CD244 gene_id:51744|Hs108|chr1 ( 365) 275 68.5 9.8e-12 CCDS53399.1 CD244 gene_id:51744|Hs108|chr1 ( 370) 263 65.9 6e-11 >>CCDS1207.1 SLAMF1 gene_id:6504|Hs108|chr1 (335 aa) initn: 2209 init1: 2209 opt: 2209 Z-score: 2577.6 bits: 485.3 E(32554): 3e-137 Smith-Waterman score: 2209; 100.0% identity (100.0% similar) in 335 aa overlap (1-335:1-335) 10 20 30 40 50 60 pF1KB6 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 YAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQKPGPLQKKLDSFPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 YAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQKPGPLQKKLDSFPAQ 250 260 270 280 290 300 310 320 330 pF1KB6 DPCTTIYVAATEPVPESVQETNSITVYASVTLPES ::::::::::::::::::::::::::::::::::: CCDS12 DPCTTIYVAATEPVPESVQETNSITVYASVTLPES 310 320 330 >>CCDS81389.1 SLAMF1 gene_id:6504|Hs108|chr1 (357 aa) initn: 1747 init1: 1747 opt: 1759 Z-score: 2053.0 bits: 388.3 E(32554): 4.9e-108 Smith-Waterman score: 1759; 91.6% identity (94.6% similar) in 297 aa overlap (1-293:1-294) 10 20 30 40 50 60 pF1KB6 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAV 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 YAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQK--PG--PLQKKLDS :::::::::::::::::::::::. . :: . : .. .: :. :: :. :. CCDS81 YAGLLGGVIMILIMVVILQLRRRATLT---TTNQYWSQNVLTQDQERCPGCLPMVKRTIT 250 260 270 280 290 300 310 320 330 pF1KB6 FPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES CCDS81 RQQWKKKALRSMPKSRNQVLFRRNLTPSQLRTLAPPYMLLPQSLSQSLSRKQIPSQSMLV 300 310 320 330 340 350 >>CCDS1210.1 CD244 gene_id:51744|Hs108|chr1 (365 aa) initn: 178 init1: 114 opt: 275 Z-score: 324.1 bits: 68.5 E(32554): 9.8e-12 Smith-Waterman score: 282; 24.1% identity (55.3% similar) in 320 aa overlap (35-330:1-315) 10 20 30 40 50 60 pF1KB6 GLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI-HIV .: :. . .:: : .:. . : :.: CCDS12 MLGQVVTLILLLLLKVYQGKGCQGSADHVV 10 20 30 70 80 90 100 pF1KB6 VTMAKSLE---NSVENKIVS-----LDPSEAG------------PPRYLGDRYKFYLENL . :. ::...:. : : ::. : : .::..: ..:: CCDS12 SISGVPLQLQPNSIQTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFIVKNL 40 50 60 70 80 90 110 120 130 140 150 160 pF1KB6 TLGIRESRKEDEGWYLMTLEK-NVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLIL .: :. ....: : : . . . . .:: .:. ....: :... .: . : : . : CCDS12 SLLIKAAQQQDSGLYCLEVTSISGKVQTATFQVFVFDKVEKPRLQGQGKILDRGRCQVAL 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB6 GCTVEKGDHVAYSWSEKAGTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTF .: : . .:.:.: . :.. .. :.. :. . .. . : :.::::.: .:.:. CCDS12 SCLVSRDGNVSYAWYR--GSKLIQTAGNLTYLDEEVDI-NGTHTYTCNVSNPVSWESHTL 160 170 180 190 200 230 240 250 260 270 280 pF1KB6 SPWPGCRTDPSETKPWAVYAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYA . :.. .: . : . .. ..: .. . . :: . .. . : :. :::: CCDS12 NLTQDCQNAHQEFRFWPFLVIIVILSALFLGTLACFCVWRRKRKEKQSETSPKEFLTIYE 210 220 230 240 250 260 290 300 310 320 330 pF1KB6 QVQ--KPGPLQKKLDSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES .:. : ... ..::. .. . .: : :: . :.:. . CCDS12 DVKDLKTRRNHEQEQTFPGGGSTIYSMIQSQSSAPTS-QEP-AYTLYSLIQPSRKSGSRK 270 280 290 300 310 320 CCDS12 RNHSPSFNSTIYEVIGKSQPKAQNPARLSRKELENFDVYS 330 340 350 360 >>CCDS53399.1 CD244 gene_id:51744|Hs108|chr1 (370 aa) initn: 178 init1: 114 opt: 263 Z-score: 310.1 bits: 65.9 E(32554): 6e-11 Smith-Waterman score: 270; 23.7% identity (54.2% similar) in 325 aa overlap (35-330:1-320) 10 20 30 40 50 60 pF1KB6 GLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI-HIV .: :. . .:: : .:. . : :.: CCDS53 MLGQVVTLILLLLLKVYQGKGCQGSADHVV 10 20 30 70 80 90 100 pF1KB6 VTMAKSLE---NSVENKIVS-----LDPSEAG------------PPRYLGDRYKFYLENL . :. ::...:. : : ::. : : .::..: ..:: CCDS53 SISGVPLQLQPNSIQTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFIVKNL 40 50 60 70 80 90 110 120 130 140 150 pF1KB6 TLGIRESRKEDEGWYLMTLE------KNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGT .: :. ....: : : . . .... : : .. : ..: :... .: . : CCDS53 SLLIKAAQQQDSGLYCLEVTSISGKVQTATFQVFVFESLLPDKVEKPRLQGQGKILDRGR 100 110 120 130 140 150 160 170 180 190 200 210 pF1KB6 CTLILGCTVEKGDHVAYSWSEKAGTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISN : . :.: : . .:.:.: . :.. .. :.. :. . .. . : :.::::.: CCDS53 CQVALSCLVSRDGNVSYAWYR--GSKLIQTAGNLTYLDEEVDI-NGTHTYTCNVSNPVSW 160 170 180 190 200 220 230 240 250 260 270 pF1KB6 NSQTFSPWPGCRTDPSETKPWAVYAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKS .:.:.. :.. .: . : . .. ..: .. . . :: . .. . : :. CCDS53 ESHTLNLTQDCQNAHQEFRFWPFLVIIVILSALFLGTLACFCVWRRKRKEKQSETSPKEF 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB6 LTIYAQVQ--KPGPLQKKLDSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES :::: .:. : ... ..::. .. . .: : :: . :.:. . CCDS53 LTIYEDVKDLKTRRNHEQEQTFPGGGSTIYSMIQSQSSAPTS-QEP-AYTLYSLIQPSRK 270 280 290 300 310 320 CCDS53 SGSRKRNHSPSFNSTIYEVIGKSQPKAQNPARLSRKELENFDVYS 330 340 350 360 370 335 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:51:05 2016 done: Fri Nov 4 20:51:06 2016 Total Scan time: 2.040 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]