FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6408, 335 aa 1>>>pF1KB6408 335 - 335 aa - 335 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9693+/-0.000354; mu= 18.2885+/- 0.022 mean_var=71.2460+/-14.649, 0's: 0 Z-trim(114.7): 118 B-trim: 421 in 1/54 Lambda= 0.151948 statistics sampled from 24616 (24743) to 24616 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.29), width: 16 Scan time: 7.630 The best scores are: opt bits E(85289) NP_003028 (OMIM: 603492) signaling lymphocytic act ( 335) 2209 493.3 3e-139 XP_016857619 (OMIM: 603492) PREDICTED: signaling l ( 338) 2038 455.8 5.9e-128 NP_001317683 (OMIM: 603492) signaling lymphocytic ( 357) 1759 394.7 1.6e-109 XP_005245513 (OMIM: 603492) PREDICTED: signaling l ( 305) 1556 350.1 3.5e-96 XP_011508207 (OMIM: 603492) PREDICTED: signaling l ( 196) 1298 293.4 2.7e-79 XP_016857620 (OMIM: 603492) PREDICTED: signaling l ( 218) 848 194.8 1.4e-49 XP_011507924 (OMIM: 180300,605554) PREDICTED: natu ( 329) 275 69.3 1.3e-11 NP_057466 (OMIM: 180300,605554) natural killer cel ( 365) 275 69.4 1.4e-11 XP_011507923 (OMIM: 180300,605554) PREDICTED: natu ( 334) 263 66.7 7.9e-11 NP_001160135 (OMIM: 180300,605554) natural killer ( 370) 263 66.7 8.6e-11 XP_016857335 (OMIM: 606620) PREDICTED: SLAM family ( 279) 239 61.4 2.7e-09 NP_064510 (OMIM: 606620) SLAM family member 8 isof ( 285) 239 61.4 2.7e-09 XP_016857334 (OMIM: 606620) PREDICTED: SLAM family ( 293) 237 61.0 3.7e-09 XP_011508080 (OMIM: 606620) PREDICTED: SLAM family ( 300) 237 61.0 3.8e-09 XP_016857333 (OMIM: 606620) PREDICTED: SLAM family ( 300) 237 61.0 3.8e-09 XP_011508079 (OMIM: 606620) PREDICTED: SLAM family ( 300) 237 61.0 3.8e-09 XP_005245402 (OMIM: 606620) PREDICTED: SLAM family ( 335) 237 61.0 4.1e-09 XP_011508078 (OMIM: 606620) PREDICTED: SLAM family ( 337) 237 61.0 4.2e-09 XP_011508077 (OMIM: 606620) PREDICTED: SLAM family ( 343) 237 61.0 4.2e-09 XP_016858245 (OMIM: 608589) PREDICTED: SLAM family ( 319) 220 57.3 5.3e-08 NP_254273 (OMIM: 608589) SLAM family member 9 isof ( 289) 219 57.0 5.7e-08 NP_001317670 (OMIM: 606620) SLAM family member 8 i ( 176) 206 54.0 2.8e-07 NP_003865 (OMIM: 604513) SLAM family member 5 isof ( 328) 208 54.6 3.3e-07 XP_011508081 (OMIM: 606620) PREDICTED: SLAM family ( 234) 204 53.6 4.7e-07 NP_001171808 (OMIM: 604513) SLAM family member 5 i ( 345) 204 53.8 6.4e-07 NP_443163 (OMIM: 606446) SLAM family member 6 isof ( 331) 202 53.3 8.4e-07 NP_001171643 (OMIM: 606446) SLAM family member 6 i ( 332) 202 53.3 8.4e-07 XP_016855704 (OMIM: 606446) PREDICTED: SLAM family ( 335) 202 53.3 8.4e-07 NP_001269521 (OMIM: 606625) SLAM family member 7 i ( 296) 200 52.9 1e-06 NP_001171810 (OMIM: 604513) SLAM family member 5 i ( 272) 199 52.6 1.1e-06 NP_067004 (OMIM: 606625) SLAM family member 7 isof ( 335) 200 52.9 1.1e-06 NP_001317671 (OMIM: 604513) SLAM family member 5 i ( 339) 199 52.7 1.3e-06 XP_011508130 (OMIM: 606625) PREDICTED: SLAM family ( 348) 199 52.7 1.4e-06 XP_011508131 (OMIM: 606625) PREDICTED: SLAM family ( 309) 194 51.6 2.7e-06 XP_011507862 (OMIM: 600684) PREDICTED: T-lymphocyt ( 598) 195 52.0 3.8e-06 XP_016856792 (OMIM: 600684) PREDICTED: T-lymphocyt ( 607) 195 52.0 3.8e-06 XP_011507858 (OMIM: 600684) PREDICTED: T-lymphocyt ( 612) 195 52.0 3.9e-06 XP_016856791 (OMIM: 600684) PREDICTED: T-lymphocyt ( 621) 195 52.0 3.9e-06 XP_011507854 (OMIM: 600684) PREDICTED: T-lymphocyt ( 679) 195 52.0 4.2e-06 XP_016856788 (OMIM: 600684) PREDICTED: T-lymphocyt ( 688) 195 52.1 4.2e-06 XP_016856787 (OMIM: 600684) PREDICTED: T-lymphocyt ( 697) 195 52.1 4.3e-06 XP_011507852 (OMIM: 600684) PREDICTED: T-lymphocyt ( 701) 195 52.1 4.3e-06 XP_011507851 (OMIM: 600684) PREDICTED: T-lymphocyt ( 702) 195 52.1 4.3e-06 XP_011507850 (OMIM: 600684) PREDICTED: T-lymphocyt ( 703) 195 52.1 4.3e-06 XP_016856786 (OMIM: 600684) PREDICTED: T-lymphocyt ( 711) 195 52.1 4.3e-06 NP_001248386 (OMIM: 600684) T-lymphocyte surface a ( 565) 189 50.7 9e-06 NP_001248385 (OMIM: 600684) T-lymphocyte surface a ( 641) 189 50.7 9.9e-06 NP_002339 (OMIM: 600684) T-lymphocyte surface anti ( 655) 189 50.7 1e-05 XP_016856790 (OMIM: 600684) PREDICTED: T-lymphocyt ( 664) 189 50.7 1e-05 XP_016856789 (OMIM: 600684) PREDICTED: T-lymphocyt ( 678) 189 50.7 1e-05 >>NP_003028 (OMIM: 603492) signaling lymphocytic activat (335 aa) initn: 2209 init1: 2209 opt: 2209 Z-score: 2620.8 bits: 493.3 E(85289): 3e-139 Smith-Waterman score: 2209; 100.0% identity (100.0% similar) in 335 aa overlap (1-335:1-335) 10 20 30 40 50 60 pF1KB6 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 YAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQKPGPLQKKLDSFPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQKPGPLQKKLDSFPAQ 250 260 270 280 290 300 310 320 330 pF1KB6 DPCTTIYVAATEPVPESVQETNSITVYASVTLPES ::::::::::::::::::::::::::::::::::: NP_003 DPCTTIYVAATEPVPESVQETNSITVYASVTLPES 310 320 330 >>XP_016857619 (OMIM: 603492) PREDICTED: signaling lymph (338 aa) initn: 2042 init1: 1747 opt: 2038 Z-score: 2418.2 bits: 455.8 E(85289): 5.9e-128 Smith-Waterman score: 2038; 93.0% identity (95.0% similar) in 341 aa overlap (1-335:1-338) 10 20 30 40 50 60 pF1KB6 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAV 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 YAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQK--PG----PLQKKL :::::::::::::::::::::::. . :: . : .. .: :. :: :::::: XP_016 YAGLLGGVIMILIMVVILQLRRRATLT---TTNQYWSQNVLTQDQERCPGCLPMPLQKKL 250 260 270 280 290 300 310 320 330 pF1KB6 DSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES ::::::::::::::::::::::::::::::::::::::::: XP_016 DSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES 300 310 320 330 >>NP_001317683 (OMIM: 603492) signaling lymphocytic acti (357 aa) initn: 1747 init1: 1747 opt: 1759 Z-score: 2087.3 bits: 394.7 E(85289): 1.6e-109 Smith-Waterman score: 1759; 91.6% identity (94.6% similar) in 297 aa overlap (1-293:1-294) 10 20 30 40 50 60 pF1KB6 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAV 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 YAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQK--PG--PLQKKLDS :::::::::::::::::::::::. . :: . : .. .: :. :: :. :. NP_001 YAGLLGGVIMILIMVVILQLRRRATLT---TTNQYWSQNVLTQDQERCPGCLPMVKRTIT 250 260 270 280 290 300 310 320 330 pF1KB6 FPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES NP_001 RQQWKKKALRSMPKSRNQVLFRRNLTPSQLRTLAPPYMLLPQSLSQSLSRKQIPSQSMLV 300 310 320 330 340 350 >>XP_005245513 (OMIM: 603492) PREDICTED: signaling lymph (305 aa) initn: 2004 init1: 1556 opt: 1556 Z-score: 1847.7 bits: 350.1 E(85289): 3.5e-96 Smith-Waterman score: 1948; 91.0% identity (91.0% similar) in 335 aa overlap (1-335:1-305) 10 20 30 40 50 60 pF1KB6 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDPKGLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HIVVTMAKSLENSVENKIVSLDPSEAGPPRYLGDRYKFYLENLTLGIRESRKEDEGWYLM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGDHVAYSWSEKA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPSETKPWAV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRTDPS------- 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 YAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQKPGPLQKKLDSFPAQ ::::::::::::::::::::::::::::::::::::: XP_005 -----------------------GKTNHYQTTVEKKSLTIYAQVQKPGPLQKKLDSFPAQ 240 250 260 270 310 320 330 pF1KB6 DPCTTIYVAATEPVPESVQETNSITVYASVTLPES ::::::::::::::::::::::::::::::::::: XP_005 DPCTTIYVAATEPVPESVQETNSITVYASVTLPES 280 290 300 >>XP_011508207 (OMIM: 603492) PREDICTED: signaling lymph (196 aa) initn: 1298 init1: 1298 opt: 1298 Z-score: 1544.7 bits: 293.4 E(85289): 2.7e-79 Smith-Waterman score: 1298; 100.0% identity (100.0% similar) in 195 aa overlap (141-335:2-196) 120 130 140 150 160 170 pF1KB6 RKEDEGWYLMTLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGD :::::::::::::::::::::::::::::: XP_011 MVSTPEIKVLNKTQENGTCTLILGCTVEKGD 10 20 30 180 190 200 210 220 230 pF1KB6 HVAYSWSEKAGTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HVAYSWSEKAGTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRT 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB6 DPSETKPWAVYAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQKPGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPSETKPWAVYAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQKPGPL 100 110 120 130 140 150 300 310 320 330 pF1KB6 QKKLDSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES ::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKKLDSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES 160 170 180 190 >>XP_016857620 (OMIM: 603492) PREDICTED: signaling lymph (218 aa) initn: 836 init1: 836 opt: 848 Z-score: 1010.9 bits: 194.8 E(85289): 1.4e-49 Smith-Waterman score: 848; 84.1% identity (89.8% similar) in 157 aa overlap (141-293:2-155) 120 130 140 150 160 170 pF1KB6 RKEDEGWYLMTLEKNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLILGCTVEKGD :::::::::::::::::::::::::::::: XP_016 MVSTPEIKVLNKTQENGTCTLILGCTVEKGD 10 20 30 180 190 200 210 220 230 pF1KB6 HVAYSWSEKAGTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVAYSWSEKAGTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTFSPWPGCRT 40 50 60 70 80 90 240 250 260 270 280 pF1KB6 DPSETKPWAVYAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYAQVQK--PG :::::::::::::::::::::::::::::::::. . :: . : .. .: :. :: XP_016 DPSETKPWAVYAGLLGGVIMILIMVVILQLRRRATLT---TTNQYWSQNVLTQDQERCPG 100 110 120 130 140 290 300 310 320 330 pF1KB6 --PLQKKLDSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES :. :. XP_016 CLPMVKRTITRQQWKKKALRSMPKSRNQVLFRRNLTPSQLRTLAPPYMLLPQSLSQSLSR 150 160 170 180 190 200 >>XP_011507924 (OMIM: 180300,605554) PREDICTED: natural (329 aa) initn: 178 init1: 114 opt: 275 Z-score: 329.7 bits: 69.3 E(85289): 1.3e-11 Smith-Waterman score: 282; 24.1% identity (55.3% similar) in 320 aa overlap (35-330:1-315) 10 20 30 40 50 60 pF1KB6 GLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI-HIV .: :. . .:: : .:. . : :.: XP_011 MLGQVVTLILLLLLKVYQGKGCQGSADHVV 10 20 30 70 80 90 100 pF1KB6 VTMAKSLE---NSVENKIVS-----LDPSEAG------------PPRYLGDRYKFYLENL . :. ::...:. : : ::. : : .::..: ..:: XP_011 SISGVPLQLQPNSIQTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFIVKNL 40 50 60 70 80 90 110 120 130 140 150 160 pF1KB6 TLGIRESRKEDEGWYLMTLEK-NVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLIL .: :. ....: : : . . . . .:: .:. ....: :... .: . : : . : XP_011 SLLIKAAQQQDSGLYCLEVTSISGKVQTATFQVFVFDKVEKPRLQGQGKILDRGRCQVAL 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB6 GCTVEKGDHVAYSWSEKAGTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTF .: : . .:.:.: . :.. .. :.. :. . .. . : :.::::.: .:.:. XP_011 SCLVSRDGNVSYAWYR--GSKLIQTAGNLTYLDEEVDI-NGTHTYTCNVSNPVSWESHTL 160 170 180 190 200 230 240 250 260 270 280 pF1KB6 SPWPGCRTDPSETKPWAVYAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYA . :.. .: . : . .. ..: .. . . :: . .. . : :. :::: XP_011 NLTQDCQNAHQEFRFWPFLVIIVILSALFLGTLACFCVWRRKRKEKQSETSPKEFLTIYE 210 220 230 240 250 260 290 300 310 320 330 pF1KB6 QVQ--KPGPLQKKLDSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES .:. : ... ..::. .. . .: : :: . :.:. . XP_011 DVKDLKTRRNHEQEQTFPGGGSTIYSMIQSQSSAPTS-QEP-AYTLYSLIQPSRKGDRFY 270 280 290 300 310 320 XP_011 SFSG >>NP_057466 (OMIM: 180300,605554) natural killer cell re (365 aa) initn: 178 init1: 114 opt: 275 Z-score: 329.0 bits: 69.4 E(85289): 1.4e-11 Smith-Waterman score: 282; 24.1% identity (55.3% similar) in 320 aa overlap (35-330:1-315) 10 20 30 40 50 60 pF1KB6 GLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI-HIV .: :. . .:: : .:. . : :.: NP_057 MLGQVVTLILLLLLKVYQGKGCQGSADHVV 10 20 30 70 80 90 100 pF1KB6 VTMAKSLE---NSVENKIVS-----LDPSEAG------------PPRYLGDRYKFYLENL . :. ::...:. : : ::. : : .::..: ..:: NP_057 SISGVPLQLQPNSIQTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFIVKNL 40 50 60 70 80 90 110 120 130 140 150 160 pF1KB6 TLGIRESRKEDEGWYLMTLEK-NVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGTCTLIL .: :. ....: : : . . . . .:: .:. ....: :... .: . : : . : NP_057 SLLIKAAQQQDSGLYCLEVTSISGKVQTATFQVFVFDKVEKPRLQGQGKILDRGRCQVAL 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB6 GCTVEKGDHVAYSWSEKAGTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISNNSQTF .: : . .:.:.: . :.. .. :.. :. . .. . : :.::::.: .:.:. NP_057 SCLVSRDGNVSYAWYR--GSKLIQTAGNLTYLDEEVDI-NGTHTYTCNVSNPVSWESHTL 160 170 180 190 200 230 240 250 260 270 280 pF1KB6 SPWPGCRTDPSETKPWAVYAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKSLTIYA . :.. .: . : . .. ..: .. . . :: . .. . : :. :::: NP_057 NLTQDCQNAHQEFRFWPFLVIIVILSALFLGTLACFCVWRRKRKEKQSETSPKEFLTIYE 210 220 230 240 250 260 290 300 310 320 330 pF1KB6 QVQ--KPGPLQKKLDSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES .:. : ... ..::. .. . .: : :: . :.:. . NP_057 DVKDLKTRRNHEQEQTFPGGGSTIYSMIQSQSSAPTS-QEP-AYTLYSLIQPSRKSGSRK 270 280 290 300 310 320 NP_057 RNHSPSFNSTIYEVIGKSQPKAQNPARLSRKELENFDVYS 330 340 350 360 >>XP_011507923 (OMIM: 180300,605554) PREDICTED: natural (334 aa) initn: 178 init1: 114 opt: 263 Z-score: 315.4 bits: 66.7 E(85289): 7.9e-11 Smith-Waterman score: 270; 23.7% identity (54.2% similar) in 325 aa overlap (35-330:1-320) 10 20 30 40 50 60 pF1KB6 GLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI-HIV .: :. . .:: : .:. . : :.: XP_011 MLGQVVTLILLLLLKVYQGKGCQGSADHVV 10 20 30 70 80 90 100 pF1KB6 VTMAKSLE---NSVENKIVS-----LDPSEAG------------PPRYLGDRYKFYLENL . :. ::...:. : : ::. : : .::..: ..:: XP_011 SISGVPLQLQPNSIQTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFIVKNL 40 50 60 70 80 90 110 120 130 140 150 pF1KB6 TLGIRESRKEDEGWYLMTLE------KNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGT .: :. ....: : : . . .... : : .. : ..: :... .: . : XP_011 SLLIKAAQQQDSGLYCLEVTSISGKVQTATFQVFVFESLLPDKVEKPRLQGQGKILDRGR 100 110 120 130 140 150 160 170 180 190 200 210 pF1KB6 CTLILGCTVEKGDHVAYSWSEKAGTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISN : . :.: : . .:.:.: . :.. .. :.. :. . .. . : :.::::.: XP_011 CQVALSCLVSRDGNVSYAWYR--GSKLIQTAGNLTYLDEEVDI-NGTHTYTCNVSNPVSW 160 170 180 190 200 220 230 240 250 260 270 pF1KB6 NSQTFSPWPGCRTDPSETKPWAVYAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKS .:.:.. :.. .: . : . .. ..: .. . . :: . .. . : :. XP_011 ESHTLNLTQDCQNAHQEFRFWPFLVIIVILSALFLGTLACFCVWRRKRKEKQSETSPKEF 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB6 LTIYAQVQ--KPGPLQKKLDSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES :::: .:. : ... ..::. .. . .: : :: . :.:. . XP_011 LTIYEDVKDLKTRRNHEQEQTFPGGGSTIYSMIQSQSSAPTS-QEP-AYTLYSLIQPSRK 270 280 290 300 310 320 XP_011 GDRFYSFSG 330 >>NP_001160135 (OMIM: 180300,605554) natural killer cell (370 aa) initn: 178 init1: 114 opt: 263 Z-score: 314.8 bits: 66.7 E(85289): 8.6e-11 Smith-Waterman score: 270; 23.7% identity (54.2% similar) in 325 aa overlap (35-330:1-320) 10 20 30 40 50 60 pF1KB6 GLLSLTFVLFLSLAFGASYGTGGRMMNCPKILRQLGSKVLLPLTYERINKSMNKSI-HIV .: :. . .:: : .:. . : :.: NP_001 MLGQVVTLILLLLLKVYQGKGCQGSADHVV 10 20 30 70 80 90 100 pF1KB6 VTMAKSLE---NSVENKIVS-----LDPSEAG------------PPRYLGDRYKFYLENL . :. ::...:. : : ::. : : .::..: ..:: NP_001 SISGVPLQLQPNSIQTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFIVKNL 40 50 60 70 80 90 110 120 130 140 150 pF1KB6 TLGIRESRKEDEGWYLMTLE------KNVSVQRFCLQLRLYEQVSTPEIKVLNKTQENGT .: :. ....: : : . . .... : : .. : ..: :... .: . : NP_001 SLLIKAAQQQDSGLYCLEVTSISGKVQTATFQVFVFESLLPDKVEKPRLQGQGKILDRGR 100 110 120 130 140 150 160 170 180 190 200 210 pF1KB6 CTLILGCTVEKGDHVAYSWSEKAGTHPLNPANSSHLLSLTLGPQHADNIYICTVSNPISN : . :.: : . .:.:.: . :.. .. :.. :. . .. . : :.::::.: NP_001 CQVALSCLVSRDGNVSYAWYR--GSKLIQTAGNLTYLDEEVDI-NGTHTYTCNVSNPVSW 160 170 180 190 200 220 230 240 250 260 270 pF1KB6 NSQTFSPWPGCRTDPSETKPWAVYAGLLGGVIMILIMVVILQLRRRGKTNHYQTTVEKKS .:.:.. :.. .: . : . .. ..: .. . . :: . .. . : :. NP_001 ESHTLNLTQDCQNAHQEFRFWPFLVIIVILSALFLGTLACFCVWRRKRKEKQSETSPKEF 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB6 LTIYAQVQ--KPGPLQKKLDSFPAQDPCTTIYVAATEPVPESVQETNSITVYASVTLPES :::: .:. : ... ..::. .. . .: : :: . :.:. . NP_001 LTIYEDVKDLKTRRNHEQEQTFPGGGSTIYSMIQSQSSAPTS-QEP-AYTLYSLIQPSRK 270 280 290 300 310 320 NP_001 SGSRKRNHSPSFNSTIYEVIGKSQPKAQNPARLSRKELENFDVYS 330 340 350 360 370 335 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:51:06 2016 done: Fri Nov 4 20:51:07 2016 Total Scan time: 7.630 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]