FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6415, 308 aa
1>>>pF1KB6415 308 - 308 aa - 308 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1627+/-0.00033; mu= 14.1749+/- 0.021
mean_var=129.3694+/-25.983, 0's: 0 Z-trim(120.4): 255 B-trim: 816 in 1/53
Lambda= 0.112761
statistics sampled from 35248 (35560) to 35248 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.417), width: 16
Scan time: 7.780
The best scores are: opt bits E(85289)
NP_004156 (OMIM: 179503) GTP-binding protein RAD [ ( 308) 2048 343.7 2.7e-94
NP_001122322 (OMIM: 179503) GTP-binding protein RA ( 308) 2048 343.7 2.7e-94
NP_859053 (OMIM: 600164) GTP-binding protein GEM [ ( 296) 1073 185.1 1.5e-46
NP_005252 (OMIM: 600164) GTP-binding protein GEM [ ( 296) 1073 185.1 1.5e-46
NP_054731 (OMIM: 610388) GTP-binding protein REM 1 ( 298) 878 153.4 5.2e-37
NP_775798 (OMIM: 616955) GTP-binding protein REM 2 ( 340) 814 143.0 7.8e-34
XP_016876548 (OMIM: 616955) PREDICTED: GTP-binding ( 372) 814 143.1 8.3e-34
XP_005267440 (OMIM: 616955) PREDICTED: GTP-binding ( 341) 810 142.4 1.2e-33
XP_016876547 (OMIM: 616955) PREDICTED: GTP-binding ( 373) 810 142.4 1.3e-33
XP_005260461 (OMIM: 610388) PREDICTED: GTP-binding ( 306) 763 134.7 2.3e-31
XP_016883322 (OMIM: 610388) PREDICTED: GTP-binding ( 306) 763 134.7 2.3e-31
XP_011527097 (OMIM: 610388) PREDICTED: GTP-binding ( 304) 762 134.5 2.5e-31
XP_016868804 (OMIM: 600164) PREDICTED: GTP-binding ( 208) 608 109.3 6.8e-24
XP_011534820 (OMIM: 616955) PREDICTED: GTP-binding ( 279) 482 88.9 1.2e-17
NP_001243750 (OMIM: 609591,615355) GTP-binding pro ( 236) 397 75.0 1.6e-13
NP_002921 (OMIM: 609592) GTP-binding protein Rit2 ( 217) 390 73.9 3.3e-13
NP_008843 (OMIM: 609591,615355) GTP-binding protei ( 219) 390 73.9 3.3e-13
NP_005393 (OMIM: 179550) ras-related protein Ral-A ( 206) 374 71.2 1.9e-12
XP_011513768 (OMIM: 179550) PREDICTED: ras-related ( 206) 374 71.2 1.9e-12
XP_006715825 (OMIM: 179550) PREDICTED: ras-related ( 206) 374 71.2 1.9e-12
XP_005263781 (OMIM: 179551) PREDICTED: ras-related ( 228) 353 67.9 2.2e-11
XP_016860110 (OMIM: 179551) PREDICTED: ras-related ( 228) 353 67.9 2.2e-11
XP_011509875 (OMIM: 179551) PREDICTED: ras-related ( 229) 353 67.9 2.2e-11
NP_002872 (OMIM: 179551) ras-related protein Ral-B ( 206) 348 67.0 3.6e-11
XP_005263785 (OMIM: 179551) PREDICTED: ras-related ( 206) 348 67.0 3.6e-11
XP_016860111 (OMIM: 179551) PREDICTED: ras-related ( 206) 348 67.0 3.6e-11
XP_005263784 (OMIM: 179551) PREDICTED: ras-related ( 206) 348 67.0 3.6e-11
XP_005263786 (OMIM: 179551) PREDICTED: ras-related ( 206) 348 67.0 3.6e-11
NP_001243749 (OMIM: 609591,615355) GTP-binding pro ( 183) 335 64.8 1.4e-10
NP_116307 (OMIM: 612664) ras-related and estrogen- ( 199) 329 63.9 3e-10
NP_056461 (OMIM: 179530) ras-related protein Rap-1 ( 184) 316 61.8 1.2e-09
NP_001010942 (OMIM: 179530) ras-related protein Ra ( 184) 316 61.8 1.2e-09
NP_060064 (OMIM: 607863) GTP-binding protein Di-Ra ( 199) 311 61.0 2.3e-09
NP_036382 (OMIM: 600098) ras-related protein R-Ras ( 204) 311 61.0 2.3e-09
XP_016874782 (OMIM: 109800,114480,137215,163200,19 ( 227) 309 60.7 3.2e-09
NP_066361 (OMIM: 179540) ras-related protein Rap-2 ( 183) 306 60.1 3.8e-09
XP_006719132 (OMIM: 109800,114480,137215,163200,19 ( 189) 304 59.8 4.9e-09
NP_203524 (OMIM: 109800,114480,137215,163200,19007 ( 189) 304 59.8 4.9e-09
NP_001177655 (OMIM: 612664) ras-related and estrog ( 180) 303 59.6 5.3e-09
NP_006261 (OMIM: 165090) ras-related protein R-Ras ( 218) 304 59.9 5.4e-09
NP_002877 (OMIM: 179541) ras-related protein Rap-2 ( 183) 302 59.5 6e-09
NP_001278825 (OMIM: 179520) ras-related protein Ra ( 184) 302 59.5 6e-09
NP_001010935 (OMIM: 179520) ras-related protein Ra ( 184) 302 59.5 6e-09
XP_016857453 (OMIM: 179520) PREDICTED: ras-related ( 184) 302 59.5 6e-09
NP_002875 (OMIM: 179520) ras-related protein Rap-1 ( 184) 302 59.5 6e-09
XP_016857451 (OMIM: 179520) PREDICTED: ras-related ( 184) 302 59.5 6e-09
XP_016857452 (OMIM: 179520) PREDICTED: ras-related ( 184) 302 59.5 6e-09
XP_011518955 (OMIM: 109800,114480,137215,163200,19 ( 188) 300 59.2 7.6e-09
NP_004976 (OMIM: 109800,114480,137215,163200,19007 ( 188) 300 59.2 7.6e-09
XP_016875610 (OMIM: 612664) PREDICTED: ras-related ( 196) 300 59.2 7.9e-09
>>NP_004156 (OMIM: 179503) GTP-binding protein RAD [Homo (308 aa)
initn: 2048 init1: 2048 opt: 2048 Z-score: 1813.9 bits: 343.7 E(85289): 2.7e-94
Smith-Waterman score: 2048; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308)
10 20 30 40 50 60
pF1KB6 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAALTPGALTAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAALTPGALTAAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AGTGTQGPRLDWPEDSEDSLSSGGSDSDESVYKVLLLGAPGVGKSALARIFGGVEDGPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AGTGTQGPRLDWPEDSEDSLSSGGSDSDESVYKVLLLGAPGVGKSALARIFGGVEDGPEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EAAGHTYDRSIVVDGEEASLMVYDIWEQDGGRWLPGHCMAMGDAYVIVYSVTDKGSFEKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EAAGHTYDRSIVVDGEEASLMVYDIWEQDGGRWLPGHCMAMGDAYVIVYSVTDKGSFEKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSK
250 260 270 280 290 300
pF1KB6 SCHDLSVL
::::::::
NP_004 SCHDLSVL
>>NP_001122322 (OMIM: 179503) GTP-binding protein RAD [H (308 aa)
initn: 2048 init1: 2048 opt: 2048 Z-score: 1813.9 bits: 343.7 E(85289): 2.7e-94
Smith-Waterman score: 2048; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308)
10 20 30 40 50 60
pF1KB6 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAALTPGALTAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAALTPGALTAAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AGTGTQGPRLDWPEDSEDSLSSGGSDSDESVYKVLLLGAPGVGKSALARIFGGVEDGPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGTGTQGPRLDWPEDSEDSLSSGGSDSDESVYKVLLLGAPGVGKSALARIFGGVEDGPEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EAAGHTYDRSIVVDGEEASLMVYDIWEQDGGRWLPGHCMAMGDAYVIVYSVTDKGSFEKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAAGHTYDRSIVVDGEEASLMVYDIWEQDGGRWLPGHCMAMGDAYVIVYSVTDKGSFEKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSK
250 260 270 280 290 300
pF1KB6 SCHDLSVL
::::::::
NP_001 SCHDLSVL
>>NP_859053 (OMIM: 600164) GTP-binding protein GEM [Homo (296 aa)
initn: 1007 init1: 814 opt: 1073 Z-score: 956.9 bits: 185.1 E(85289): 1.5e-46
Smith-Waterman score: 1073; 57.9% identity (79.8% similar) in 292 aa overlap (23-308:9-296)
10 20 30 40 50 60
pF1KB6 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAALTPGALTAAA
:.:.. : : .: :.:.: : :.. : .
NP_859 MTLNNVTMRQGTV--GMQPQQQRWSIPADGRHLMVQKEPHQYSHRN
10 20 30 40
70 80 90 100 110
pF1KB6 AGTGTQGP--RLDWPEDSEDSLSSGGSDSDESVYKVLLLGAPGVGKSALARIFGGVEDGP
..: : .: :: ::. : :.: .. :.:.:.: :::::.:: ::.::.:.
NP_859 RHSATPEDHCRRSWSSDSTDSVIS--SESGNTYYRVVLIGEQGVGKSTLANIFAGVHDSM
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 EA--EAAGH-TYDRSIVVDGEEASLMVYDIWEQDG-GRWLPGHCMAMGDAYVIVYSVTDK
.. :. :. ::.:...:::: :.... :.::. : ..:: ::: .::::.::::.::.
NP_859 DSDCEVLGEDTYERTLMVDGESATIILLDMWENKGENEWLHDHCMQVGDAYLIVYSITDR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 GSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSA
.:::::::::.::::::::.:.::::::::::::: :::::.::::::::::::::::::
NP_859 ASFEKASELRIQLRRARQTEDIPIILVGNKSDLVRCREVSVSEGRACAVVFDCKFIETSA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 ALHHNVQALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGRIVARNSRKMA
:..:::. ::::.:::.:::::::: : :: : .:.::. .::.:: :.:::.:...::
NP_859 AVQHNVKELFEGIVRQVRLRRDSKEKNERRLAYQKRKESMPRKARRFWGKIVAKNNKNMA
230 240 250 260 270 280
300
pF1KB6 FRAKSKSCHDLSVL
:. :::::::::::
NP_859 FKLKSKSCHDLSVL
290
>>NP_005252 (OMIM: 600164) GTP-binding protein GEM [Homo (296 aa)
initn: 1007 init1: 814 opt: 1073 Z-score: 956.9 bits: 185.1 E(85289): 1.5e-46
Smith-Waterman score: 1073; 57.9% identity (79.8% similar) in 292 aa overlap (23-308:9-296)
10 20 30 40 50 60
pF1KB6 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAALTPGALTAAA
:.:.. : : .: :.:.: : :.. : .
NP_005 MTLNNVTMRQGTV--GMQPQQQRWSIPADGRHLMVQKEPHQYSHRN
10 20 30 40
70 80 90 100 110
pF1KB6 AGTGTQGP--RLDWPEDSEDSLSSGGSDSDESVYKVLLLGAPGVGKSALARIFGGVEDGP
..: : .: :: ::. : :.: .. :.:.:.: :::::.:: ::.::.:.
NP_005 RHSATPEDHCRRSWSSDSTDSVIS--SESGNTYYRVVLIGEQGVGKSTLANIFAGVHDSM
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 EA--EAAGH-TYDRSIVVDGEEASLMVYDIWEQDG-GRWLPGHCMAMGDAYVIVYSVTDK
.. :. :. ::.:...:::: :.... :.::. : ..:: ::: .::::.::::.::.
NP_005 DSDCEVLGEDTYERTLMVDGESATIILLDMWENKGENEWLHDHCMQVGDAYLIVYSITDR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 GSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSA
.:::::::::.::::::::.:.::::::::::::: :::::.::::::::::::::::::
NP_005 ASFEKASELRIQLRRARQTEDIPIILVGNKSDLVRCREVSVSEGRACAVVFDCKFIETSA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 ALHHNVQALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGRIVARNSRKMA
:..:::. ::::.:::.:::::::: : :: : .:.::. .::.:: :.:::.:...::
NP_005 AVQHNVKELFEGIVRQVRLRRDSKEKNERRLAYQKRKESMPRKARRFWGKIVAKNNKNMA
230 240 250 260 270 280
300
pF1KB6 FRAKSKSCHDLSVL
:. :::::::::::
NP_005 FKLKSKSCHDLSVL
290
>>NP_054731 (OMIM: 610388) GTP-binding protein REM 1 [Ho (298 aa)
initn: 724 init1: 511 opt: 878 Z-score: 785.4 bits: 153.4 E(85289): 5.2e-37
Smith-Waterman score: 907; 51.4% identity (75.5% similar) in 294 aa overlap (34-308:12-298)
10 20 30 40 50 60
pF1KB6 NGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRS---MPVDERDLQAALTPGALTAAA
:::::. .:.. : : :: :...
NP_054 MTLNTEQEAKTPLHRRASTPLPLSPRGHQ----PGRLSTVP
10 20 30
70 80 90 100
pF1KB6 AGTGTQGPRLDW----------PEDSEDSLSSGGSDSD---ESVYKVLLLGAPGVGKSAL
. : .: ::: : . :. :: .:::. :..:.:.::: :::::..:
NP_054 S-TQSQHPRLGQSASLNPPTQKPSPAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSL
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB6 ARIFGGVEDGPEAEAAGH-TYDRSIVVDGEEASLMVYDIWEQD--GGRWLPGHCMAMGDA
: .:.: .. : :. .:.:...::::...:.: : :: . : :. :.:
NP_054 ASLFAGKQERDLHEQLGEDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSA
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB6 YVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVV
::::::..:.::::.:::::.::::..:.: :::::::::.::.: :::::.::::::::
NP_054 YVIVYSIADRGSFESASELRIQLRRTHQADHVPIILVGNKADLARCREVSVEEGRACAVV
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB6 FDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGR
::::::::::.:.::: ::::::::.:::: ... :.. . :: ::...:.:::.:
NP_054 FDCKFIETSATLQHNVAELFEGVVRQLRLRR--RDSAAKEPPAPRRPASLAQRARRFLAR
220 230 240 250 260 270
290 300
pF1KB6 IVARNSRKMAFRAKSKSCHDLSVL
..::..:. :..:.:::::.:.::
NP_054 LTARSARRRALKARSKSCHNLAVL
280 290
>>NP_775798 (OMIM: 616955) GTP-binding protein REM 2 [Ho (340 aa)
initn: 798 init1: 440 opt: 814 Z-score: 728.4 bits: 143.0 E(85289): 7.8e-34
Smith-Waterman score: 822; 49.0% identity (68.6% similar) in 306 aa overlap (21-308:50-340)
10 20 30 40 50
pF1KB6 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAA
: :.. : .:. : .: :::: .
NP_775 PSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKH----
20 30 40 50 60 70
60 70 80 90 100
pF1KB6 LTPGALTAAAAGTGTQGPRLDWPED-----SEDSLSSG--GSDSDESVYKVLLLGAPGVG
: : : .:::: . : :::.:: . . ....::.:.: :::
NP_775 ----QLRRAQAVD-----ELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVG
80 90 100 110 120
110 120 130 140 150 160
pF1KB6 KSALARIFGGVE--DGPEAEAAGHTYDRSIVVDGEEASLMVYDIWEQ-DGGRWLPGHCMA
::.:: :::.. .. : : ::.: :.:: ::..:.::::::: :.: :: ::.
NP_775 KSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB6 MGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRA
:::..::.::::. :: :. : ..:: .: :.:.:::::::::.::::::..:::
NP_775 TGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRH
190 200 210 220 230 240
230 240 250 260 270
pF1KB6 CAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQ--------AGTRRRE
: ...:: ::::::::::.. ::::.:::::::: ..:...: : :::
NP_775 LAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRE
250 260 270 280 290 300
280 290 300
pF1KB6 SLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL
:: :::::::. .: ::.. :. .:.::::::::
NP_775 SLTKKAKRFLANLVPRNAK--FFKQRSRSCHDLSVL
310 320 330 340
>>XP_016876548 (OMIM: 616955) PREDICTED: GTP-binding pro (372 aa)
initn: 798 init1: 440 opt: 814 Z-score: 728.0 bits: 143.1 E(85289): 8.3e-34
Smith-Waterman score: 822; 49.0% identity (68.6% similar) in 306 aa overlap (21-308:82-372)
10 20 30 40 50
pF1KB6 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAA
: :.. : .:. : .: :::: .
XP_016 IPLIASFSLPSHFILEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKH----
60 70 80 90 100
60 70 80 90 100
pF1KB6 LTPGALTAAAAGTGTQGPRLDWPED-----SEDSLSSG--GSDSDESVYKVLLLGAPGVG
: : : .:::: . : :::.:: . . ....::.:.: :::
XP_016 ----QLRRAQAVD-----ELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVG
110 120 130 140 150
110 120 130 140 150 160
pF1KB6 KSALARIFGGVE--DGPEAEAAGHTYDRSIVVDGEEASLMVYDIWEQ-DGGRWLPGHCMA
::.:: :::.. .. : : ::.: :.:: ::..:.::::::: :.: :: ::.
XP_016 KSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQ
160 170 180 190 200 210
170 180 190 200 210 220
pF1KB6 MGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRA
:::..::.::::. :: :. : ..:: .: :.:.:::::::::.::::::..:::
XP_016 TGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRH
220 230 240 250 260 270
230 240 250 260 270
pF1KB6 CAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQ--------AGTRRRE
: ...:: ::::::::::.. ::::.:::::::: ..:...: : :::
XP_016 LAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRE
280 290 300 310 320 330
280 290 300
pF1KB6 SLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL
:: :::::::. .: ::.. :. .:.::::::::
XP_016 SLTKKAKRFLANLVPRNAK--FFKQRSRSCHDLSVL
340 350 360 370
>>XP_005267440 (OMIM: 616955) PREDICTED: GTP-binding pro (341 aa)
initn: 807 init1: 440 opt: 810 Z-score: 724.9 bits: 142.4 E(85289): 1.2e-33
Smith-Waterman score: 818; 49.0% identity (67.9% similar) in 308 aa overlap (21-308:50-341)
10 20 30 40 50
pF1KB6 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAA
: :.. : .:. : .: :::: .
XP_005 PSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKH----
20 30 40 50 60 70
60 70 80 90 100
pF1KB6 LTPGALTAAAAGTGTQGPRLDWPED-----SEDSLSSG--GSDSDESVYKVLLLGAPGVG
: : : .:::: . : :::.:: . . ....::.:.: :::
XP_005 ----QLRRAQAVD-----ELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVG
80 90 100 110 120
110 120 130 140 150
pF1KB6 KSALARIFGGVEDG----PEAEAAGHTYDRSIVVDGEEASLMVYDIWEQ-DGGRWLPGHC
::.:: :::.. :: : ::.: :.:: ::..:.::::::: :.: :: ::
XP_005 KSTLAGTFGGLQGDSAHEPENPAED-TYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHC
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 MAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEG
. :::..::.::::. :: :. : ..:: .: :.:.:::::::::.::::::..::
XP_005 LQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEG
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 RACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQ--------AGTRR
: : ...:: ::::::::::.. ::::.:::::::: ..:...: : :
XP_005 RHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPAR
250 260 270 280 290 300
280 290 300
pF1KB6 RESLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL
:::: :::::::. .: ::.. :. .:.::::::::
XP_005 RESLTKKAKRFLANLVPRNAK--FFKQRSRSCHDLSVL
310 320 330 340
>>XP_016876547 (OMIM: 616955) PREDICTED: GTP-binding pro (373 aa)
initn: 807 init1: 440 opt: 810 Z-score: 724.4 bits: 142.4 E(85289): 1.3e-33
Smith-Waterman score: 818; 49.0% identity (67.9% similar) in 308 aa overlap (21-308:82-373)
10 20 30 40 50
pF1KB6 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAA
: :.. : .:. : .: :::: .
XP_016 IPLIASFSLPSHFILEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKH----
60 70 80 90 100
60 70 80 90 100
pF1KB6 LTPGALTAAAAGTGTQGPRLDWPED-----SEDSLSSG--GSDSDESVYKVLLLGAPGVG
: : : .:::: . : :::.:: . . ....::.:.: :::
XP_016 ----QLRRAQAVD-----ELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVG
110 120 130 140 150
110 120 130 140 150
pF1KB6 KSALARIFGGVEDG----PEAEAAGHTYDRSIVVDGEEASLMVYDIWEQ-DGGRWLPGHC
::.:: :::.. :: : ::.: :.:: ::..:.::::::: :.: :: ::
XP_016 KSTLAGTFGGLQGDSAHEPENPAED-TYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHC
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB6 MAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEG
. :::..::.::::. :: :. : ..:: .: :.:.:::::::::.::::::..::
XP_016 LQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEG
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB6 RACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQ--------AGTRR
: : ...:: ::::::::::.. ::::.:::::::: ..:...: : :
XP_016 RHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPAR
280 290 300 310 320 330
280 290 300
pF1KB6 RESLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL
:::: :::::::. .: ::.. :. .:.::::::::
XP_016 RESLTKKAKRFLANLVPRNAK--FFKQRSRSCHDLSVL
340 350 360 370
>>XP_005260461 (OMIM: 610388) PREDICTED: GTP-binding pro (306 aa)
initn: 750 init1: 511 opt: 763 Z-score: 684.2 bits: 134.7 E(85289): 2.3e-31
Smith-Waterman score: 890; 50.0% identity (73.2% similar) in 302 aa overlap (34-308:12-306)
10 20 30 40 50 60
pF1KB6 NGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRS---MPVDERDLQAALTPGALTAAA
:::::. .:.. : : :: :...
XP_005 MTLNTEQEAKTPLHRRASTPLPLSPRGHQ----PGRLSTVP
10 20 30
70 80 90 100
pF1KB6 AGTGTQGPRLDW----------PEDSEDSLSSGGSDSD---ESVYKVLLLGAPGVGKSAL
. : .: ::: : . :. :: .:::. :..:.:.::: :::::..:
XP_005 S-TQSQHPRLGQSASLNPPTQKPSPAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSL
40 50 60 70 80 90
110 120 130 140 150
pF1KB6 ARIFGGVEDGPEAEAAGH---------TYDRSIVVDGEEASLMVYDIWEQD--GGRWLPG
: .:.: .. : : .:.:...::::...:.: : :: . :
XP_005 ASLFAGKQERDLHEQLGDPALPSVAEDVYERTLTVDGEDTTLVVVDTWEAEKLDKSWSQE
100 110 120 130 140 150
160 170 180 190 200 210
pF1KB6 HCMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVD
:. :.:::::::..:.::::.:::::.::::..:.: :::::::::.::.: :::::.
XP_005 SCLQGGSAYVIVYSIADRGSFESASELRIQLRRTHQADHVPIILVGNKADLARCREVSVE
160 170 180 190 200 210
220 230 240 250 260 270
pF1KB6 EGRACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGK
::::::::::::::::::.:.::: ::::::::.:::: ... :.. . :: ::..
XP_005 EGRACAVVFDCKFIETSATLQHNVAELFEGVVRQLRLRR--RDSAAKEPPAPRRPASLAQ
220 230 240 250 260 270
280 290 300
pF1KB6 KAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL
.:.:::.:..::..:. :..:.:::::.:.::
XP_005 RARRFLARLTARSARRRALKARSKSCHNLAVL
280 290 300
308 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:52:22 2016 done: Fri Nov 4 20:52:23 2016
Total Scan time: 7.780 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]