Result of FASTA (omim) for
pF1KB6419
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6419, 309 aa
1>>>pF1KB6419 309 - 309 aa - 309 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7037+/-0.000413; mu= 0.9885+/- 0.026
mean_var=234.7155+/-48.171, 0's: 0 Z-trim(119.0): 11 B-trim: 44 in 1/55
Lambda= 0.083715
statistics sampled from 32491 (32502) to 32491 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.381), width: 16
Scan time: 7.350
The best scores are: opt bits E(85289)
NP_002422 (OMIM: 602659) CDK-activating kinase ass ( 309) 2058 261.2 1.9e-69
XP_005267744 (OMIM: 602659) PREDICTED: CDK-activat ( 309) 2058 261.2 1.9e-69
XP_016876821 (OMIM: 602659) PREDICTED: CDK-activat ( 294) 1837 234.5 2e-61
XP_005267745 (OMIM: 602659) PREDICTED: CDK-activat ( 278) 1788 228.5 1.2e-59
NP_001171434 (OMIM: 602659) CDK-activating kinase ( 267) 1244 162.8 6.9e-40
XP_016876823 (OMIM: 602659) PREDICTED: CDK-activat ( 188) 1225 160.4 2.6e-39
XP_016876822 (OMIM: 602659) PREDICTED: CDK-activat ( 188) 1225 160.4 2.6e-39
>>NP_002422 (OMIM: 602659) CDK-activating kinase assembl (309 aa)
initn: 2058 init1: 2058 opt: 2058 Z-score: 1367.6 bits: 261.2 E(85289): 1.9e-69
Smith-Waterman score: 2058; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309)
10 20 30 40 50 60
pF1KB6 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA
250 260 270 280 290 300
pF1KB6 FSGLFWQPS
:::::::::
NP_002 FSGLFWQPS
>>XP_005267744 (OMIM: 602659) PREDICTED: CDK-activating (309 aa)
initn: 2058 init1: 2058 opt: 2058 Z-score: 1367.6 bits: 261.2 E(85289): 1.9e-69
Smith-Waterman score: 2058; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309)
10 20 30 40 50 60
pF1KB6 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA
250 260 270 280 290 300
pF1KB6 FSGLFWQPS
:::::::::
XP_005 FSGLFWQPS
>>XP_016876821 (OMIM: 602659) PREDICTED: CDK-activating (294 aa)
initn: 1837 init1: 1837 opt: 1837 Z-score: 1223.6 bits: 234.5 E(85289): 2e-61
Smith-Waterman score: 1837; 100.0% identity (100.0% similar) in 279 aa overlap (31-309:16-294)
10 20 30 40 50 60
pF1KB6 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV
::::::::::::::::::::::::::::::
XP_016 MQIRSCSVAQTGVHCCESCVDLLFVRGAGNCPECGTPLRKSNFRV
10 20 30 40
70 80 90 100 110 120
pF1KB6 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA
230 240 250 260 270 280
pF1KB6 FSGLFWQPS
:::::::::
XP_016 FSGLFWQPS
290
>>XP_005267745 (OMIM: 602659) PREDICTED: CDK-activating (278 aa)
initn: 1815 init1: 1788 opt: 1788 Z-score: 1192.0 bits: 228.5 E(85289): 1.2e-59
Smith-Waterman score: 1788; 98.2% identity (99.3% similar) in 275 aa overlap (1-275:1-275)
10 20 30 40 50 60
pF1KB6 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA
:::::::::::::::::::::::::::::: .. .
XP_005 LEEALYEYQPLQIETYGPHVPELEMLGRLGGFDTISLI
250 260 270
pF1KB6 FSGLFWQPS
>>NP_001171434 (OMIM: 602659) CDK-activating kinase asse (267 aa)
initn: 1241 init1: 1241 opt: 1244 Z-score: 837.1 bits: 162.8 E(85289): 6.9e-40
Smith-Waterman score: 1697; 86.4% identity (86.4% similar) in 309 aa overlap (1-309:1-267)
10 20 30 40 50 60
pF1KB6 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK
::::::: :::::::::::
NP_001 QAFLDEL------------------------------------------GQHISLAPIHK
190
250 260 270 280 290 300
pF1KB6 LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA
200 210 220 230 240 250
pF1KB6 FSGLFWQPS
:::::::::
NP_001 FSGLFWQPS
260
>>XP_016876823 (OMIM: 602659) PREDICTED: CDK-activating (188 aa)
initn: 1225 init1: 1225 opt: 1225 Z-score: 826.7 bits: 160.4 E(85289): 2.6e-39
Smith-Waterman score: 1225; 100.0% identity (100.0% similar) in 188 aa overlap (122-309:1-188)
100 110 120 130 140 150
pF1KB6 LREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEAL
::::::::::::::::::::::::::::::
XP_016 MEIYQKENKDVIQKNKLKLTREQEELEEAL
10 20 30
160 170 180 190 200 210
pF1KB6 EVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQ
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB6 LEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGY
100 110 120 130 140 150
280 290 300
pF1KB6 LNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS
::::::::::::::::::::::::::::::::::::::
XP_016 LNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS
160 170 180
>>XP_016876822 (OMIM: 602659) PREDICTED: CDK-activating (188 aa)
initn: 1225 init1: 1225 opt: 1225 Z-score: 826.7 bits: 160.4 E(85289): 2.6e-39
Smith-Waterman score: 1225; 100.0% identity (100.0% similar) in 188 aa overlap (122-309:1-188)
100 110 120 130 140 150
pF1KB6 LREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEAL
::::::::::::::::::::::::::::::
XP_016 MEIYQKENKDVIQKNKLKLTREQEELEEAL
10 20 30
160 170 180 190 200 210
pF1KB6 EVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQ
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB6 LEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGY
100 110 120 130 140 150
280 290 300
pF1KB6 LNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS
::::::::::::::::::::::::::::::::::::::
XP_016 LNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS
160 170 180
309 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:52:57 2016 done: Fri Nov 4 20:52:58 2016
Total Scan time: 7.350 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]