FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6423, 309 aa
  1>>>pF1KB6423 309 - 309 aa - 309 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9737+/-0.000711; mu= 17.1354+/- 0.043
 mean_var=60.1503+/-12.322, 0's: 0 Z-trim(108.7): 29  B-trim: 0 in 0/49
 Lambda= 0.165369
 statistics sampled from 10351 (10379) to 10351 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.319), width:  16
 Scan time:  2.790

The best scores are:                                      opt bits E(32554)
CCDS9563.1 SLC39A2 gene_id:29986|Hs108|chr14       ( 309) 2045 496.0 1.5e-140
CCDS58303.1 SLC39A2 gene_id:29986|Hs108|chr14      (  85)  552 139.5 8.7e-34
CCDS1055.1 SLC39A1 gene_id:27173|Hs108|chr1        ( 324)  487 124.3 1.2e-28
CCDS12093.1 SLC39A3 gene_id:29985|Hs108|chr19      ( 314)  355 92.8 3.6e-19


>>CCDS9563.1 SLC39A2 gene_id:29986|Hs108|chr14            (309 aa)
 initn: 2045 init1: 2045 opt: 2045  Z-score: 2636.8  bits: 496.0 E(32554): 1.5e-140
Smith-Waterman score: 2045; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309)

               10        20        30        40        50        60
pF1KB6 MEQLLGIKLGCLFALLALTLGCGLTPICFKWFQIDAARGHHRLVLRLLGCISAGVFLGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 MEQLLGIKLGCLFALLALTLGCGLTPICFKWFQIDAARGHHRLVLRLLGCISAGVFLGAG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 FMHMTAEALEEIESQIQKFMVQNRSASERNSSGDADSAHMEYPYGELIISLGFFFVFFLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 FMHMTAEALEEIESQIQKFMVQNRSASERNSSGDADSAHMEYPYGELIISLGFFFVFFLE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 SLALQCCPGAAGGSTVQDEEWGGAHIFELHSHGHLPSPSKGPLRALVLLLSLSFHSVFEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 SLALQCCPGAAGGSTVQDEEWGGAHIFELHSHGHLPSPSKGPLRALVLLLSLSFHSVFEG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 LAVGLQPTVAATVQLCLAVLAHKGLVVFGVGMRLVHLGTSSRWAVFSILLLALMSPLGLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 LAVGLQPTVAATVQLCLAVLAHKGLVVFGVGMRLVHLGTSSRWAVFSILLLALMSPLGLA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 VGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLEILPRELASPEAPLAKWSCVAAGFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 VGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLEILPRELASPEAPLAKWSCVAAGFA
              250       260       270       280       290       300

                
pF1KB6 FMAFIALWA
       :::::::::
CCDS95 FMAFIALWA
                

>>CCDS58303.1 SLC39A2 gene_id:29986|Hs108|chr14           (85 aa)
 initn: 552 init1: 552 opt: 552  Z-score: 720.1  bits: 139.5 E(32554): 8.7e-34
Smith-Waterman score: 552; 100.0% identity (100.0% similar) in 82 aa overlap (1-82:1-82)

               10        20        30        40        50        60
pF1KB6 MEQLLGIKLGCLFALLALTLGCGLTPICFKWFQIDAARGHHRLVLRLLGCISAGVFLGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MEQLLGIKLGCLFALLALTLGCGLTPICFKWFQIDAARGHHRLVLRLLGCISAGVFLGAG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 FMHMTAEALEEIESQIQKFMVQNRSASERNSSGDADSAHMEYPYGELIISLGFFFVFFLE
       ::::::::::::::::::::::                                      
CCDS58 FMHMTAEALEEIESQIQKFMVQISK                                   
               70        80                                        

>>CCDS1055.1 SLC39A1 gene_id:27173|Hs108|chr1             (324 aa)
 initn: 500 init1: 228 opt: 487  Z-score: 627.7  bits: 124.3 E(32554): 1.2e-28
Smith-Waterman score: 536; 36.5% identity (63.9% similar) in 310 aa overlap (5-302:27-316)

                                     10        20        30        
pF1KB6                       MEQLLGIKLGCLFALLALTLGCGLTPICFKWFQIDAAR
                                 : .::: :  ::.::: :.:.:::         .
CCDS10 MGPWGEPELLVWRPEAVASEPPVPVGLEVKLGALVLLLVLTLLCSLVPICVLRRPGANHE
               10        20        30        40        50        60

       40          50        60        70        80        90      
pF1KB6 GH--HRLVLRLLGCISAGVFLGAGFMHMTAEALEEIESQIQKFMVQNRSASERNSSGDAD
       :   .. .: :..:...::::.. .. .  . :  :.  .  . :               
CCDS10 GSASRQKALSLVSCFAGGVFLATCLLDLLPDYLAAIDEALAALHVT--------------
               70        80        90       100                    

        100       110       120       130       140         150    
pF1KB6 SAHMEYPYGELIISLGFFFVFFLESLALQCCPGAAGGSTVQDEE--WGGAHIFELHSHGH
          ...:  :.:...:::.:. .:...:      .: : ... .   : ..    : :  
CCDS10 ---LQFPLQEFILAMGFFLVLVMEQITLAY-KEQSGPSPLEETRALLGTVNGGPQHWHDG
           110       120       130        140       150       160  

            160            170       180       190       200       
pF1KB6 --LPSPSKGP-----LRALVLLLSLSFHSVFEGLAVGLQPTVAATVQLCLAVLAHKGLVV
         .:. : .:     ::: ::..::..::::::::::::   : ...::::.: :::...
CCDS10 PGVPQASGAPATPSALRACVLVFSLALHSVFEGLAVGLQRDRARAMELCLALLLHKGILA
            170       180       190       200       210       220  

       210       220       230       240       250        260      
pF1KB6 FGVGMRLVHLGTSSRWAVFSILLLALMSPLGLAVGLAVTGGDSEGG-RGLAQAVLEGVAA
        ....::..    .. ..   .:.. :.:::...: :.  ..: :  . :::.::::.::
CCDS10 VSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAAL--AESAGPLHQLAQSVLEGMAA
            230       240       250       260         270       280

        270       280       290       300          
pF1KB6 GTFLYVTFLEILPRELASPEAPLAKWSCVAAGFAFMAFIALWA 
       :::::.:::::::.:::: :  . :   . ::::..        
CCDS10 GTFLYITFLEILPQELASSEQRILKVILLLAGFALLTGLLFIQI
              290       300       310       320    

>>CCDS12093.1 SLC39A3 gene_id:29985|Hs108|chr19           (314 aa)
 initn: 352 init1: 153 opt: 355  Z-score: 457.7  bits: 92.8 E(32554): 3.6e-19
Smith-Waterman score: 423; 32.1% identity (60.9% similar) in 327 aa overlap (1-303:1-307)

               10        20        30        40         50         
pF1KB6 MEQLLGIKLGCLFALLALTLGCGLTPICFKWFQIDAARGHH-RLVLRLLGCISAGVFLGA
       : .::  :. :. ... . :  .: :.  : .. :  ..:. . .: : . ...::::..
CCDS12 MVKLLVAKILCMVGVFFFMLLGSLLPV--KIIETDFEKAHRSKKILSLCNTFGGGVFLAT
               10        20          30        40        50        

      60        70        80        90       100       110         
pF1KB6 GFMHMTAEALEEIESQIQKFMVQNRSASERNSSGDADSAHMEYPYGELIISLGFFFVFFL
        :  .    :  .. ..:: .          : :  ..   .:: .: :. ::::.. ::
CCDS12 CFNAL----LPAVREKLQKVL----------SLGHIST---DYPLAETILLLGFFMTVFL
       60            70                  80           90       100 

     120                 130       140              150        160 
pF1KB6 ESLAL---QCCPG-------AAGGSTVQDEEW-----GGA--HIFELHSHGHLPSPS-KG
       :.: :   .  :.        ::... .: :.     :::  : . .. ::: :: : .:
CCDS12 EQLILTFRKEKPSFIDLETFNAGSDVGSDSEYESPFMGGARGHALYVEPHGHGPSLSVQG
             110       120       130       140       150       160 

                  170       180       190       200       210      
pF1KB6 -----PLRALVLLLSLSFHSVFEGLAVGLQPTVAATVQLCLAVLAHKGLVVFGVGMRLVH
            :.: : : ..:: ::::::::.:::     .:.: ..: .:. ::. ..:. ...
CCDS12 LSRASPVRLLSLAFALSAHSVFEGLALGLQEEGEKVVSLFVGVAVHETLVAVALGISMAR
             170       180       190       200       210       220 

        220       230       240       250       260       270      
pF1KB6 LGTSSRWAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLE
        .   : :.   . .. : :::...::.. ....  : ..:...:.:.:.::::..::::
CCDS12 SAMPLRDAAKLAVTVSAMIPLGIGLGLGIESAQGVPG-SVASVLLQGLAGGTFLFITFLE
             230       240       250        260       270       280

        280       290       300          
pF1KB6 ILPRELASPEAPLAKWSCVAAGFAFMAFIALWA 
       :: .::      : :   .. :.. .:       
CCDS12 ILAKELEEKSDRLLKVLFLVLGYTVLAGMVFLKW
              290       300       310    




309 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 18:11:55 2016 done: Sat Nov  5 18:11:56 2016
 Total Scan time:  2.790 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]