FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6426, 286 aa 1>>>pF1KB6426 286 - 286 aa - 286 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.2594+/-0.000333; mu= 21.0104+/- 0.021 mean_var=59.5696+/-11.735, 0's: 0 Z-trim(114.9): 49 B-trim: 39 in 1/52 Lambda= 0.166174 statistics sampled from 25031 (25081) to 25031 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.294), width: 16 Scan time: 6.800 The best scores are: opt bits E(85289) NP_996756 (OMIM: 176875) serine/threonine-protein ( 286) 2005 488.8 5.1e-138 NP_002699 (OMIM: 176875) serine/threonine-protein ( 330) 1897 462.9 3.5e-130 NP_001008709 (OMIM: 176875) serine/threonine-prote ( 341) 1897 463.0 3.6e-130 NP_996759 (OMIM: 600590) serine/threonine-protein ( 327) 1719 420.3 2.4e-117 NP_002700 (OMIM: 600590) serine/threonine-protein ( 327) 1719 420.3 2.4e-117 NP_001231903 (OMIM: 176914) serine/threonine-prote ( 337) 1695 414.5 1.3e-115 NP_002701 (OMIM: 176914) serine/threonine-protein ( 323) 1685 412.1 6.9e-115 XP_011536807 (OMIM: 176914) PREDICTED: serine/thre ( 330) 1685 412.1 7e-115 XP_011536806 (OMIM: 176914) PREDICTED: serine/thre ( 362) 1685 412.2 7.5e-115 NP_001009552 (OMIM: 176916) serine/threonine-prote ( 309) 908 225.8 7.9e-59 NP_002706 (OMIM: 176915) serine/threonine-protein ( 309) 895 222.7 6.9e-58 NP_002711 (OMIM: 602035) serine/threonine-protein ( 307) 891 221.7 1.3e-57 NP_001290432 (OMIM: 602035) serine/threonine-prote ( 307) 891 221.7 1.3e-57 XP_011517149 (OMIM: 612725) PREDICTED: serine/thre ( 293) 846 210.9 2.3e-54 NP_002712 (OMIM: 612725) serine/threonine-protein ( 305) 846 211.0 2.3e-54 NP_001116827 (OMIM: 612725) serine/threonine-prote ( 342) 846 211.0 2.5e-54 NP_001290436 (OMIM: 602035) serine/threonine-prote ( 228) 757 189.5 5e-48 NP_001290435 (OMIM: 602035) serine/threonine-prote ( 228) 757 189.5 5e-48 XP_016878893 (OMIM: 602035) PREDICTED: serine/thre ( 228) 757 189.5 5e-48 XP_016878892 (OMIM: 602035) PREDICTED: serine/thre ( 228) 757 189.5 5e-48 NP_001116841 (OMIM: 612725) serine/threonine-prote ( 283) 715 179.5 6.3e-45 NP_001191213 (OMIM: 600658) serine/threonine-prote ( 477) 686 172.8 1.1e-42 NP_006238 (OMIM: 600658) serine/threonine-protein ( 499) 686 172.8 1.2e-42 XP_016882424 (OMIM: 600658) PREDICTED: serine/thre ( 551) 686 172.8 1.3e-42 NP_001290433 (OMIM: 602035) serine/threonine-prote ( 273) 678 170.6 2.9e-42 XP_006721124 (OMIM: 602035) PREDICTED: serine/thre ( 273) 678 170.6 2.9e-42 NP_001124164 (OMIM: 114105) serine/threonine-prote ( 469) 643 162.5 1.4e-39 XP_016863854 (OMIM: 114105) PREDICTED: serine/thre ( 509) 643 162.5 1.5e-39 NP_001124163 (OMIM: 114105) serine/threonine-prote ( 511) 643 162.5 1.5e-39 NP_000935 (OMIM: 114105) serine/threonine-protein ( 521) 643 162.5 1.5e-39 XP_016869100 (OMIM: 114107) PREDICTED: serine/thre ( 418) 633 160.0 6.9e-39 XP_016869099 (OMIM: 114107) PREDICTED: serine/thre ( 439) 633 160.0 7.1e-39 NP_001230904 (OMIM: 114107) serine/threonine-prote ( 502) 633 160.1 7.8e-39 NP_005596 (OMIM: 114107) serine/threonine-protein ( 512) 633 160.1 7.9e-39 NP_001230903 (OMIM: 114107) serine/threonine-prote ( 521) 633 160.1 8e-39 NP_001276898 (OMIM: 114106) serine/threonine-prote ( 410) 627 158.6 1.8e-38 XP_016871868 (OMIM: 114106) PREDICTED: serine/thre ( 426) 627 158.6 1.9e-38 XP_005270001 (OMIM: 114106) PREDICTED: serine/thre ( 514) 627 158.7 2.2e-38 NP_001135826 (OMIM: 114106) serine/threonine-prote ( 515) 627 158.7 2.2e-38 NP_066955 (OMIM: 114106) serine/threonine-protein ( 524) 627 158.7 2.2e-38 NP_001135825 (OMIM: 114106) serine/threonine-prote ( 525) 627 158.7 2.2e-38 NP_001276897 (OMIM: 114106) serine/threonine-prote ( 514) 434 112.4 1.8e-24 XP_011530341 (OMIM: 602256) PREDICTED: serine/thre ( 753) 370 97.2 1e-19 NP_006230 (OMIM: 602256) serine/threonine-protein ( 753) 370 97.2 1e-19 NP_689412 (OMIM: 300109) serine/threonine-protein ( 591) 308 82.3 2.5e-15 XP_016885101 (OMIM: 300109) PREDICTED: serine/thre ( 563) 187 53.2 1.3e-06 NP_689410 (OMIM: 300109) serine/threonine-protein ( 625) 187 53.3 1.4e-06 XP_005274610 (OMIM: 300109) PREDICTED: serine/thre ( 653) 187 53.3 1.5e-06 NP_006231 (OMIM: 300109) serine/threonine-protein ( 653) 187 53.3 1.5e-06 >>NP_996756 (OMIM: 176875) serine/threonine-protein phos (286 aa) initn: 2005 init1: 2005 opt: 2005 Z-score: 2598.9 bits: 488.8 E(85289): 5.1e-138 Smith-Waterman score: 2005; 100.0% identity (100.0% similar) in 286 aa overlap (1-286:1-286) 10 20 30 40 50 60 pF1KB6 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 FTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 FTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMS 190 200 210 220 230 240 250 260 270 280 pF1KB6 VDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK :::::::::::::::::::::::::::::::::::::::::::::: NP_996 VDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 250 260 270 280 >>NP_002699 (OMIM: 176875) serine/threonine-protein phos (330 aa) initn: 1991 init1: 1897 opt: 1897 Z-score: 2458.2 bits: 462.9 E(85289): 3.5e-130 Smith-Waterman score: 1897; 100.0% identity (100.0% similar) in 268 aa overlap (19-286:63-330) 10 20 30 40 pF1KB6 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGD :::::::::::::::::::::::::::::: NP_002 NEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGD 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB6 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB6 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB6 VQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB6 CGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 280 290 300 310 320 330 >>NP_001008709 (OMIM: 176875) serine/threonine-protein p (341 aa) initn: 1897 init1: 1897 opt: 1897 Z-score: 2458.0 bits: 463.0 E(85289): 3.6e-130 Smith-Waterman score: 1897; 100.0% identity (100.0% similar) in 268 aa overlap (19-286:74-341) 10 20 30 40 pF1KB6 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGD :::::::::::::::::::::::::::::: NP_001 NEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGD 50 60 70 80 90 100 50 60 70 80 90 100 pF1KB6 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF 110 120 130 140 150 160 110 120 130 140 150 160 pF1KB6 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD 170 180 190 200 210 220 170 180 190 200 210 220 pF1KB6 VQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 230 240 250 260 270 280 230 240 250 260 270 280 pF1KB6 CGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 290 300 310 320 330 340 >>NP_996759 (OMIM: 600590) serine/threonine-protein phos (327 aa) initn: 1731 init1: 1633 opt: 1719 Z-score: 2227.6 bits: 420.3 E(85289): 2.4e-117 Smith-Waterman score: 1719; 91.0% identity (97.0% similar) in 268 aa overlap (19-286:62-326) 10 20 30 40 pF1KB6 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGD ::::::: ::::::::::::::.::::::: NP_996 AEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGD 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB6 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_996 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTF 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB6 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: NP_996 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKD 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB6 VQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY :::::::::::::::::.::.:::..:::::::::::::::::::::::::::::::::: NP_996 VQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB6 CGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK ::::::::.:::::::::::::::::..: :.:: :..::: .:::.::::.. :: NP_996 CGEFDNAGGMMSVDETLMCSFQILKPSEK-KAKY-QYGGLN-SGRPVTPPRTANPPKKR 280 290 300 310 320 >>NP_002700 (OMIM: 600590) serine/threonine-protein phos (327 aa) initn: 1731 init1: 1633 opt: 1719 Z-score: 2227.6 bits: 420.3 E(85289): 2.4e-117 Smith-Waterman score: 1719; 91.0% identity (97.0% similar) in 268 aa overlap (19-286:62-326) 10 20 30 40 pF1KB6 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGD ::::::: ::::::::::::::.::::::: NP_002 AEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGD 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB6 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_002 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTF 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB6 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: NP_002 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKD 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB6 VQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY :::::::::::::::::.::.:::..:::::::::::::::::::::::::::::::::: NP_002 VQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB6 CGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK ::::::::.:::::::::::::::::..: :.:: :..::: .:::.::::.. :: NP_002 CGEFDNAGGMMSVDETLMCSFQILKPSEK-KAKY-QYGGLN-SGRPVTPPRTANPPKKR 280 290 300 310 320 >>NP_001231903 (OMIM: 176914) serine/threonine-protein p (337 aa) initn: 1840 init1: 1685 opt: 1695 Z-score: 2196.3 bits: 414.5 E(85289): 1.3e-115 Smith-Waterman score: 1706; 93.5% identity (95.4% similar) in 261 aa overlap (19-279:63-314) 10 20 30 40 pF1KB6 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGD :::::::::::::::::::::::::::::: NP_001 NEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGD 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB6 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB6 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB6 VQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY : :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB6 CGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK :::::::::::::::::::::::::::.:.: . . ::.:::: NP_001 CGEFDNAGAMMSVDETLMCSFQILKPAEKKKPN---------ATRPVTPPRVASGLNPSI 280 290 300 310 320 NP_001 QKASNYRNNTVLYE 330 >>NP_002701 (OMIM: 176914) serine/threonine-protein phos (323 aa) initn: 1812 init1: 1685 opt: 1685 Z-score: 2183.6 bits: 412.1 E(85289): 6.9e-115 Smith-Waterman score: 1712; 91.5% identity (94.5% similar) in 271 aa overlap (19-286:63-323) 10 20 30 40 pF1KB6 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGD :::::::::::::::::::::::::::::: NP_002 NEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGD 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB6 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB6 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB6 VQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY : :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB6 CGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGG-RPITPPRN--SAKAK :::::::::::::::::::::::::::.:.: :.. ::.::::. . .:: NP_002 CGEFDNAGAMMSVDETLMCSFQILKPAEKKK----------PNATRPVTPPRGMITKQAK 280 290 300 310 320 pF1KB6 K : NP_002 K >>XP_011536807 (OMIM: 176914) PREDICTED: serine/threonin (330 aa) initn: 1789 init1: 1685 opt: 1685 Z-score: 2183.5 bits: 412.1 E(85289): 7e-115 Smith-Waterman score: 1706; 93.5% identity (95.4% similar) in 261 aa overlap (19-279:63-314) 10 20 30 40 pF1KB6 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGD :::::::::::::::::::::::::::::: XP_011 NEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGD 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB6 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB6 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB6 VQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY : :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB6 CGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK :::::::::::::::::::::::::::.:.: . . ::.:::: XP_011 CGEFDNAGAMMSVDETLMCSFQILKPAEKKKPN---------ATRPVTPPRELPIFFTSL 280 290 300 310 320 XP_011 SMGFSAA 330 >>XP_011536806 (OMIM: 176914) PREDICTED: serine/threonin (362 aa) initn: 1816 init1: 1685 opt: 1685 Z-score: 2183.0 bits: 412.2 E(85289): 7.5e-115 Smith-Waterman score: 1710; 91.8% identity (94.4% similar) in 267 aa overlap (19-285:63-320) 10 20 30 40 pF1KB6 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGD :::::::::::::::::::::::::::::: XP_011 NEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGD 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB6 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTF 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB6 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB6 VQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY : :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB6 CGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK :::::::::::::::::::::::::::.:.: . . ::.:::: . :. XP_011 CGEFDNAGAMMSVDETLMCSFQILKPAEKKKPN---------ATRPVTPPRATQLAQYQT 280 290 300 310 320 XP_011 PCLPERTIPHTSCSGLVNKRTVNWSLYSWTDWLDLSLAS 330 340 350 360 >>NP_001009552 (OMIM: 176916) serine/threonine-protein p (309 aa) initn: 837 init1: 569 opt: 908 Z-score: 1177.1 bits: 225.8 E(85289): 7.9e-59 Smith-Waterman score: 908; 52.1% identity (77.5% similar) in 240 aa overlap (19-257:56-294) 10 20 30 40 pF1KB6 MSDSEKLNLDSIIGRLLEGDIHGQYYDLLRLFEYGGFPPESNYLFLGD ::.:::..::..::. :: :..::::.:: NP_001 NQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGD 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB6 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKT ::::: :.::. ::.: :..::: . .:::::: .:...::::::: :.: : ..:: NP_001 YVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKY 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB6 FTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDK ::: :. ::..:.:: .::: ::::::.......:: . : .:: .: .::::::::: NP_001 FTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPD- 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB6 DVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPN : ::: . ::...::: .. : : . : :. ::::.: .::.. :..::.::::: NP_001 DRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPN 210 220 230 240 250 260 230 240 250 260 270 280 pF1KB6 YCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK :: . : .:.: .:.:: :: . :: . NP_001 YCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL 270 280 290 300 286 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:54:16 2016 done: Fri Nov 4 20:54:17 2016 Total Scan time: 6.800 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]