FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6431, 312 aa
  1>>>pF1KB6431 312 - 312 aa - 312 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9971+/-0.000303; mu= 13.5702+/- 0.019
 mean_var=91.9773+/-17.901, 0's: 0 Z-trim(119.0): 33  B-trim: 100 in 1/55
 Lambda= 0.133732
 statistics sampled from 32540 (32573) to 32540 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.382), width:  16
 Scan time:  7.880

The best scores are:                                      opt bits E(85289)
NP_002519 (OMIM: 602656,616415) endonuclease III-l ( 312) 2126 419.7 3.8e-117
XP_016878742 (OMIM: 602656,616415) PREDICTED: endo ( 356) 1829 362.4 7.4e-100
NP_001305123 (OMIM: 602656,616415) endonuclease II ( 194) 1254 251.3 1.1e-66
NP_001305122 (OMIM: 602656,616415) endonuclease II ( 255)  890 181.2   2e-45


>>NP_002519 (OMIM: 602656,616415) endonuclease III-like   (312 aa)
 initn: 2126 init1: 2126 opt: 2126  Z-score: 2224.2  bits: 419.7 E(85289): 3.8e-117
Smith-Waterman score: 2126; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:1-312)

               10        20        30        40        50        60
pF1KB6 MCSPQESGMTALSARMLTRSRSLGPGAGPRGCREEPGPLRRREAAAEARKSHSPVKRPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MCSPQESGMTALSARMLTRSRSLGPGAGPRGCREEPGPLRRREAAAEARKSHSPVKRPRK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 AQRLRVAYEGSDSEKGEGAEPLKVPVWEPQDWQQQLVNIRAMRNKKDAPVDHLGTEHCYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AQRLRVAYEGSDSEKGEGAEPLKVPVWEPQDWQQQLVNIRAMRNKKDAPVDHLGTEHCYD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 SSAPPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLIYPVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SSAPPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLIYPVG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 FWRSKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FWRSKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 HVHRIANRLRWTKKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HVHRIANRLRWTKKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHAC
              250       260       270       280       290       300

              310  
pF1KB6 LNQALCPAAQGL
       ::::::::::::
NP_002 LNQALCPAAQGL
              310  

>>XP_016878742 (OMIM: 602656,616415) PREDICTED: endonucl  (356 aa)
 initn: 1823 init1: 1823 opt: 1829  Z-score: 1913.7  bits: 362.4 E(85289): 7.4e-100
Smith-Waterman score: 1832; 91.0% identity (92.9% similar) in 311 aa overlap (1-311:1-301)

               10        20        30        40        50        60
pF1KB6 MCSPQESGMTALSARMLTRSRSLGPGAGPRGCREEPGPLRRREAAAEARKSHSPVKRPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCSPQESGMTALSARMLTRSRSLGPGAGPRGCREEPGPLRRREAAAEARKSHSPVKRPRK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 AQRLRVAYEGSDSEKGEGAEPLKVPVWEPQDWQQQLVNIRAMRNKKDAPVDHLGTEHCYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQRLRVAYEGSDSEKGEGAEPLKVPVWEPQDWQQQLVNIRAMRNKKDAPVDHLGTEHCYD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 SSAPPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLIYPVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAPPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLIYPVG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 FWRSKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWRSKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 HVHRIANRLRWTKKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHAC
       ::::::::::::::::::::::::::::::::   .:  :   ::  .   :..:   . 
XP_016 HVHRIANRLRWTKKATKSPEETRAALEEWLPR---YEYVG---GFLGRRAHPARPL--SA
              250       260       270             280       290    

              310                                                  
pF1KB6 LNQALCPAAQGL                                                
       :.:   :  ::                                                 
XP_016 LTQP--PPPQGAVARDQWTLGGLRPADLSACAPSLPRLPQPSPLPGRPGSLMAAWLWPRC
              300       310       320       330       340       350

>>NP_001305123 (OMIM: 602656,616415) endonuclease III-li  (194 aa)
 initn: 1254 init1: 1254 opt: 1254  Z-score: 1318.0  bits: 251.3 E(85289): 1.1e-66
Smith-Waterman score: 1254; 100.0% identity (100.0% similar) in 187 aa overlap (126-312:8-194)

         100       110       120       130       140       150     
pF1KB6 LVNIRAMRNKKDAPVDHLGTEHCYDSSAPPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLR
                                     ::::::::::::::::::::::::::::::
NP_001                        MRARTVRKVRRYQVLLSLMLSSQTKDQVTAGAMQRLR
                                      10        20        30       

         160       170       180       190       200       210     
pF1KB6 ARGLTVDSILQTDDATLGKLIYPVGFWRSKVKYIKQTSAILQQHYGGDIPASVAELVALP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARGLTVDSILQTDDATLGKLIYPVGFWRSKVKYIKQTSAILQQHYGGDIPASVAELVALP
        40        50        60        70        80        90       

         220       230       240       250       260       270     
pF1KB6 GVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANRLRWTKKATKSPEETRAALEEWLPRELW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANRLRWTKKATKSPEETRAALEEWLPRELW
       100       110       120       130       140       150       

         280       290       300       310  
pF1KB6 HEINGLLVGFGQQTCLPVHPRCHACLNQALCPAAQGL
       :::::::::::::::::::::::::::::::::::::
NP_001 HEINGLLVGFGQQTCLPVHPRCHACLNQALCPAAQGL
       160       170       180       190    

>>NP_001305122 (OMIM: 602656,616415) endonuclease III-li  (255 aa)
 initn: 890 init1: 890 opt: 890  Z-score: 936.7  bits: 181.2 E(85289): 2e-45
Smith-Waterman score: 1641; 81.7% identity (81.7% similar) in 312 aa overlap (1-312:1-255)

               10        20        30        40        50        60
pF1KB6 MCSPQESGMTALSARMLTRSRSLGPGAGPRGCREEPGPLRRREAAAEARKSHSPVKRPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MCSPQESGMTALSARMLTRSRSLGPGAGPRGCREEPGPLRRREAAAEARKSHSPVKRPRK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 AQRLRVAYEGSDSEKGEGAEPLKVPVWEPQDWQQQLVNIRAMRNKKDAPVDHLGTEHCYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQRLRVAYEGSDSEKGEGAEPLKVPVWEPQDWQQQLVNIRAMRNKKDAPVDHLGTEHCYD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 SSAPPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLIYPVG
       ::::::                                                      
NP_001 SSAPPK------------------------------------------------------
                                                                   

              190       200       210       220       230       240
pF1KB6 FWRSKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDT
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---SKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDT
           130       140       150       160       170       180   

              250       260       270       280       290       300
pF1KB6 HVHRIANRLRWTKKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVHRIANRLRWTKKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHAC
           190       200       210       220       230       240   

              310  
pF1KB6 LNQALCPAAQGL
       ::::::::::::
NP_001 LNQALCPAAQGL
           250     




312 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 17:37:24 2016 done: Fri Nov  4 17:37:25 2016
 Total Scan time:  7.880 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]