FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6434, 344 aa 1>>>pF1KB6434 344 - 344 aa - 344 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2311+/-0.000358; mu= 16.4348+/- 0.022 mean_var=65.7030+/-13.416, 0's: 0 Z-trim(112.8): 17 B-trim: 0 in 0/54 Lambda= 0.158227 statistics sampled from 21790 (21800) to 21790 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.256), width: 16 Scan time: 7.990 The best scores are: opt bits E(85289) NP_060037 (OMIM: 606828) N-acetyl-D-glucosamine ki ( 390) 2311 536.5 3.6e-152 NP_001317355 (OMIM: 606828) N-acetyl-D-glucosamine ( 293) 1979 460.6 1.9e-129 XP_005264472 (OMIM: 606828) PREDICTED: N-acetyl-D- ( 293) 1979 460.6 1.9e-129 XP_011531259 (OMIM: 606828) PREDICTED: N-acetyl-D- ( 293) 1979 460.6 1.9e-129 NP_001317354 (OMIM: 606828) N-acetyl-D-glucosamine ( 293) 1979 460.6 1.9e-129 XP_005264470 (OMIM: 606828) PREDICTED: N-acetyl-D- ( 293) 1979 460.6 1.9e-129 XP_016859929 (OMIM: 606828) PREDICTED: N-acetyl-D- ( 263) 1299 305.4 9e-83 >>NP_060037 (OMIM: 606828) N-acetyl-D-glucosamine kinase (390 aa) initn: 2311 init1: 2311 opt: 2311 Z-score: 2852.9 bits: 536.5 E(85289): 3.6e-152 Smith-Waterman score: 2311; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:47-390) 10 20 30 pF1KB6 MAAIYGGVEGGGTRSEVLLVSEDGKILAEA :::::::::::::::::::::::::::::: NP_060 SGAVPRQLEGRRCQAGRDANGGTSSDGSSSMAAIYGGVEGGGTRSEVLLVSEDGKILAEA 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 DGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGGDQEDAGRILIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGGDQEDAGRILIEE 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 LRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSESGCGGWGHMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSESGCGGWGHMM 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB6 GDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGILTHLYRDFDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 GDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGILTHLYRDFDK 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB6 CRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGKIGLPILCVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 CRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGKIGLPILCVG 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB6 SVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGARHIGHLLPMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGARHIGHLLPMD 320 330 340 350 360 370 340 pF1KB6 YSANAIAFYSYTFS :::::::::::::: NP_060 YSANAIAFYSYTFS 380 390 >>NP_001317355 (OMIM: 606828) N-acetyl-D-glucosamine kin (293 aa) initn: 1979 init1: 1979 opt: 1979 Z-score: 2445.2 bits: 460.6 E(85289): 1.9e-129 Smith-Waterman score: 1979; 100.0% identity (100.0% similar) in 293 aa overlap (52-344:1-293) 30 40 50 60 70 80 pF1KB6 EDGKILAEADGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGGDQE :::::::::::::::::::::::::::::: NP_001 MVNRAKRKAGVDPLVPLRSLGLSLSGGDQE 10 20 30 90 100 110 120 130 140 pF1KB6 DAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSES 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 GCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGIL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 THLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGK 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 IGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGAR 220 230 240 250 260 270 330 340 pF1KB6 HIGHLLPMDYSANAIAFYSYTFS ::::::::::::::::::::::: NP_001 HIGHLLPMDYSANAIAFYSYTFS 280 290 >>XP_005264472 (OMIM: 606828) PREDICTED: N-acetyl-D-gluc (293 aa) initn: 1979 init1: 1979 opt: 1979 Z-score: 2445.2 bits: 460.6 E(85289): 1.9e-129 Smith-Waterman score: 1979; 100.0% identity (100.0% similar) in 293 aa overlap (52-344:1-293) 30 40 50 60 70 80 pF1KB6 EDGKILAEADGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGGDQE :::::::::::::::::::::::::::::: XP_005 MVNRAKRKAGVDPLVPLRSLGLSLSGGDQE 10 20 30 90 100 110 120 130 140 pF1KB6 DAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSES 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 GCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGIL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 THLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGK 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 IGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGAR 220 230 240 250 260 270 330 340 pF1KB6 HIGHLLPMDYSANAIAFYSYTFS ::::::::::::::::::::::: XP_005 HIGHLLPMDYSANAIAFYSYTFS 280 290 >>XP_011531259 (OMIM: 606828) PREDICTED: N-acetyl-D-gluc (293 aa) initn: 1979 init1: 1979 opt: 1979 Z-score: 2445.2 bits: 460.6 E(85289): 1.9e-129 Smith-Waterman score: 1979; 100.0% identity (100.0% similar) in 293 aa overlap (52-344:1-293) 30 40 50 60 70 80 pF1KB6 EDGKILAEADGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGGDQE :::::::::::::::::::::::::::::: XP_011 MVNRAKRKAGVDPLVPLRSLGLSLSGGDQE 10 20 30 90 100 110 120 130 140 pF1KB6 DAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSES 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 GCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGIL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 THLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGK 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 IGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGAR 220 230 240 250 260 270 330 340 pF1KB6 HIGHLLPMDYSANAIAFYSYTFS ::::::::::::::::::::::: XP_011 HIGHLLPMDYSANAIAFYSYTFS 280 290 >>NP_001317354 (OMIM: 606828) N-acetyl-D-glucosamine kin (293 aa) initn: 1979 init1: 1979 opt: 1979 Z-score: 2445.2 bits: 460.6 E(85289): 1.9e-129 Smith-Waterman score: 1979; 100.0% identity (100.0% similar) in 293 aa overlap (52-344:1-293) 30 40 50 60 70 80 pF1KB6 EDGKILAEADGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGGDQE :::::::::::::::::::::::::::::: NP_001 MVNRAKRKAGVDPLVPLRSLGLSLSGGDQE 10 20 30 90 100 110 120 130 140 pF1KB6 DAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSES 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 GCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGIL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 THLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGK 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 IGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGAR 220 230 240 250 260 270 330 340 pF1KB6 HIGHLLPMDYSANAIAFYSYTFS ::::::::::::::::::::::: NP_001 HIGHLLPMDYSANAIAFYSYTFS 280 290 >>XP_005264470 (OMIM: 606828) PREDICTED: N-acetyl-D-gluc (293 aa) initn: 1979 init1: 1979 opt: 1979 Z-score: 2445.2 bits: 460.6 E(85289): 1.9e-129 Smith-Waterman score: 1979; 100.0% identity (100.0% similar) in 293 aa overlap (52-344:1-293) 30 40 50 60 70 80 pF1KB6 EDGKILAEADGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGGDQE :::::::::::::::::::::::::::::: XP_005 MVNRAKRKAGVDPLVPLRSLGLSLSGGDQE 10 20 30 90 100 110 120 130 140 pF1KB6 DAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSES 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 GCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGIL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 THLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGK 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 IGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGAR 220 230 240 250 260 270 330 340 pF1KB6 HIGHLLPMDYSANAIAFYSYTFS ::::::::::::::::::::::: XP_005 HIGHLLPMDYSANAIAFYSYTFS 280 290 >>XP_016859929 (OMIM: 606828) PREDICTED: N-acetyl-D-gluc (263 aa) initn: 1319 init1: 1299 opt: 1299 Z-score: 1607.0 bits: 305.4 E(85289): 9e-83 Smith-Waterman score: 1299; 99.0% identity (99.5% similar) in 197 aa overlap (1-197:47-243) 10 20 30 pF1KB6 MAAIYGGVEGGGTRSEVLLVSEDGKILAEA :::::::::::::::::::::::::::::: XP_016 SGAVPRQLEGRRCQAGRDANGGTSSDGSSSMAAIYGGVEGGGTRSEVLLVSEDGKILAEA 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 DGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGGDQEDAGRILIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGGDQEDAGRILIEE 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 LRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSESGCGGWGHMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSESGCGGWGHMM 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB6 GDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGILTHLYRDFDK :::::::::::::::::::::::::::::::::::::::::::: .: XP_016 GDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVLSRETPFPAISSGRLG 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB6 CRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPVLFQGKIGLPILCVG XP_016 RCWADTS 260 344 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:58:52 2016 done: Fri Nov 4 22:58:53 2016 Total Scan time: 7.990 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]