Result of FASTA (omim) for
pF1KB6436
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6436, 311 aa
1>>>pF1KB6436 311 - 311 aa - 311 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1684+/-0.000279; mu= 18.0599+/- 0.018
mean_var=80.5318+/-16.019, 0's: 0 Z-trim(120.4): 85 B-trim: 0 in 0/51
Lambda= 0.142919
statistics sampled from 35517 (35607) to 35517 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.417), width: 16
Scan time: 8.190
The best scores are: opt bits E(85289)
NP_001186391 (OMIM: 600866) programmed cell death ( 311) 2221 466.8 2.6e-131
NP_002589 (OMIM: 600866) programmed cell death pro ( 344) 2036 428.7 8.4e-120
XP_016866415 (OMIM: 600866) PREDICTED: programmed ( 298) 1678 354.8 1.3e-97
NP_001186392 (OMIM: 600866) programmed cell death ( 195) 1377 292.6 4.4e-79
NP_001186393 (OMIM: 600866) programmed cell death ( 188) 1372 291.5 8.8e-79
NP_659005 (OMIM: 600866) programmed cell death pro ( 228) 1192 254.5 1.5e-67
NP_001186390 (OMIM: 600866) programmed cell death ( 221) 1187 253.4 3e-67
NP_115722 (OMIM: 615661) programmed cell death pro ( 358) 243 59.0 1.7e-08
XP_005273224 (OMIM: 606425,609070,609820) PREDICTE ( 345) 150 39.8 0.0097
>>NP_001186391 (OMIM: 600866) programmed cell death prot (311 aa)
initn: 2221 init1: 2221 opt: 2221 Z-score: 2478.6 bits: 466.8 E(85289): 2.6e-131
Smith-Waterman score: 2221; 100.0% identity (100.0% similar) in 311 aa overlap (1-311:1-311)
10 20 30 40 50 60
pF1KB6 MAAAGARPVELGFAESAPAWRLRSEQFPSKVYAPLPGRPDAFHRCIFLFCCREQPCCAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAGARPVELGFAESAPAWRLRSEQFPSKVYAPLPGRPDAFHRCIFLFCCREQPCCAGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RVFRNQLPRKNDFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVFRNQLPRKNDFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 YCSKEHQTLDWRLGHKQACAQPDHLDHIIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCSKEHQTLDWRLGHKQACAQPDHLDHIIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EIIGSMGEALEEELDSMAKHESREDKIFQKFKTQIALEPEQILRYGRGIAPIWISGENIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIIGSMGEALEEELDSMAKHESREDKIFQKFKTQIALEPEQILRYGRGIAPIWISGENIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QEKDIPDCPCGAKRILEFQVMPQLLNYLKADRLGKSIDWGILAVFTCAESCSLGTGYTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEKDIPDCPCGAKRILEFQVMPQLLNYLKADRLGKSIDWGILAVFTCAESCSLGTGYTEE
250 260 270 280 290 300
310
pF1KB6 FVWKQDVTDTP
:::::::::::
NP_001 FVWKQDVTDTP
310
>>NP_002589 (OMIM: 600866) programmed cell death protein (344 aa)
initn: 2022 init1: 2022 opt: 2036 Z-score: 2271.8 bits: 428.7 E(85289): 8.4e-120
Smith-Waterman score: 2138; 90.4% identity (90.4% similar) in 343 aa overlap (2-311:2-344)
10 20 30
pF1KB6 MAAAGARPVELGFAESAPAWRLRSEQFPSKV-----------------------------
::::::::::::::::::::::::::::::
NP_002 MAAAGARPVELGFAESAPAWRLRSEQFPSKVGGRPAWLGAAGLPGPQALACELCGRPLSF
10 20 30 40 50 60
40 50 60 70 80
pF1KB6 ----YAPLPGRPDAFHRCIFLFCCREQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LLQVYAPLPGRPDAFHRCIFLFCCREQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPET
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB6 GESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDH
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB6 IIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYSEIIGSMGEALEEELDSMAKHESREDKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYSEIIGSMGEALEEELDSMAKHESREDKI
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB6 FQKFKTQIALEPEQILRYGRGIAPIWISGENIPQEKDIPDCPCGAKRILEFQVMPQLLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FQKFKTQIALEPEQILRYGRGIAPIWISGENIPQEKDIPDCPCGAKRILEFQVMPQLLNY
250 260 270 280 290 300
270 280 290 300 310
pF1KB6 LKADRLGKSIDWGILAVFTCAESCSLGTGYTEEFVWKQDVTDTP
::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKADRLGKSIDWGILAVFTCAESCSLGTGYTEEFVWKQDVTDTP
310 320 330 340
>>XP_016866415 (OMIM: 600866) PREDICTED: programmed cell (298 aa)
initn: 1664 init1: 1664 opt: 1678 Z-score: 1873.7 bits: 354.8 E(85289): 1.3e-97
Smith-Waterman score: 1780; 88.7% identity (88.7% similar) in 291 aa overlap (2-259:2-292)
10 20 30
pF1KB6 MAAAGARPVELGFAESAPAWRLRSEQFPSKV-----------------------------
::::::::::::::::::::::::::::::
XP_016 MAAAGARPVELGFAESAPAWRLRSEQFPSKVGGRPAWLGAAGLPGPQALACELCGRPLSF
10 20 30 40 50 60
40 50 60 70 80
pF1KB6 ----YAPLPGRPDAFHRCIFLFCCREQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLQVYAPLPGRPDAFHRCIFLFCCREQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPET
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB6 GESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDH
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB6 IIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYSEIIGSMGEALEEELDSMAKHESREDKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYSEIIGSMGEALEEELDSMAKHESREDKI
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB6 FQKFKTQIALEPEQILRYGRGIAPIWISGENIPQEKDIPDCPCGAKRILEFQVMPQLLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQKFKTQIALEPEQILRYGRGIAPIWISGENIPQEKDIPDCPCGAKRILEFQFSDTVY
250 260 270 280 290
270 280 290 300 310
pF1KB6 LKADRLGKSIDWGILAVFTCAESCSLGTGYTEEFVWKQDVTDTP
>>NP_001186392 (OMIM: 600866) programmed cell death prot (195 aa)
initn: 1394 init1: 1377 opt: 1377 Z-score: 1540.8 bits: 292.6 E(85289): 4.4e-79
Smith-Waterman score: 1377; 97.4% identity (99.5% similar) in 192 aa overlap (1-192:1-192)
10 20 30 40 50 60
pF1KB6 MAAAGARPVELGFAESAPAWRLRSEQFPSKVYAPLPGRPDAFHRCIFLFCCREQPCCAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAGARPVELGFAESAPAWRLRSEQFPSKVYAPLPGRPDAFHRCIFLFCCREQPCCAGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RVFRNQLPRKNDFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVFRNQLPRKNDFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 YCSKEHQTLDWRLGHKQACAQPDHLDHIIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCSKEHQTLDWRLGHKQACAQPDHLDHIIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EIIGSMGEALEEELDSMAKHESREDKIFQKFKTQIALEPEQILRYGRGIAPIWISGENIP
:::::::. ...
NP_001 EIIGSMGKQFQDFIH
190
>>NP_001186393 (OMIM: 600866) programmed cell death prot (188 aa)
initn: 1372 init1: 1372 opt: 1372 Z-score: 1535.4 bits: 291.5 E(85289): 8.8e-79
Smith-Waterman score: 1372; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187)
10 20 30 40 50 60
pF1KB6 MAAAGARPVELGFAESAPAWRLRSEQFPSKVYAPLPGRPDAFHRCIFLFCCREQPCCAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAGARPVELGFAESAPAWRLRSEQFPSKVYAPLPGRPDAFHRCIFLFCCREQPCCAGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RVFRNQLPRKNDFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVFRNQLPRKNDFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 YCSKEHQTLDWRLGHKQACAQPDHLDHIIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCSKEHQTLDWRLGHKQACAQPDHLDHIIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EIIGSMGEALEEELDSMAKHESREDKIFQKFKTQIALEPEQILRYGRGIAPIWISGENIP
:::::::
NP_001 EIIGSMGI
>>NP_659005 (OMIM: 600866) programmed cell death protein (228 aa)
initn: 1368 init1: 1176 opt: 1192 Z-score: 1333.7 bits: 254.5 E(85289): 1.5e-67
Smith-Waterman score: 1294; 83.0% identity (84.8% similar) in 224 aa overlap (2-192:2-225)
10 20 30
pF1KB6 MAAAGARPVELGFAESAPAWRLRSEQFPSKV-----------------------------
::::::::::::::::::::::::::::::
NP_659 MAAAGARPVELGFAESAPAWRLRSEQFPSKVGGRPAWLGAAGLPGPQALACELCGRPLSF
10 20 30 40 50 60
40 50 60 70 80
pF1KB6 ----YAPLPGRPDAFHRCIFLFCCREQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 LLQVYAPLPGRPDAFHRCIFLFCCREQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPET
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB6 GESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 GESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDH
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB6 IIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYSEIIGSMGEALEEELDSMAKHESREDKI
::::::::::::::::::::::::::::::::::::::::. ...
NP_659 IIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYSEIIGSMGKQFQDFIH
190 200 210 220
210 220 230 240 250 260
pF1KB6 FQKFKTQIALEPEQILRYGRGIAPIWISGENIPQEKDIPDCPCGAKRILEFQVMPQLLNY
>>NP_001186390 (OMIM: 600866) programmed cell death prot (221 aa)
initn: 1173 init1: 1173 opt: 1187 Z-score: 1328.3 bits: 253.4 E(85289): 3e-67
Smith-Waterman score: 1289; 84.9% identity (84.9% similar) in 219 aa overlap (2-187:2-220)
10 20 30
pF1KB6 MAAAGARPVELGFAESAPAWRLRSEQFPSKV-----------------------------
::::::::::::::::::::::::::::::
NP_001 MAAAGARPVELGFAESAPAWRLRSEQFPSKVGGRPAWLGAAGLPGPQALACELCGRPLSF
10 20 30 40 50 60
40 50 60 70 80
pF1KB6 ----YAPLPGRPDAFHRCIFLFCCREQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLQVYAPLPGRPDAFHRCIFLFCCREQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPET
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB6 GESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDH
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB6 IIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYSEIIGSMGEALEEELDSMAKHESREDKI
::::::::::::::::::::::::::::::::::::::::
NP_001 IIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYSEIIGSMGI
190 200 210 220
210 220 230 240 250 260
pF1KB6 FQKFKTQIALEPEQILRYGRGIAPIWISGENIPQEKDIPDCPCGAKRILEFQVMPQLLNY
>>NP_115722 (OMIM: 615661) programmed cell death protein (358 aa)
initn: 265 init1: 218 opt: 243 Z-score: 273.6 bits: 59.0 E(85289): 1.7e-08
Smith-Waterman score: 296; 28.9% identity (50.2% similar) in 305 aa overlap (30-309:61-353)
10 20 30 40 50
pF1KB6 MAAAGARPVELGFAESAPAWRLRSEQFPSKVYAPLPGRPDAFHRCIFLFCCREQPCCAG
.:: :: : : ::: . .: : : .:
NP_115 KLGGIPDALPTVAAPRPVCQRCGQPLALVVQVYCPLEGSP--FHRLLHVFACACPGCSTG
40 50 60 70 80
60 70 80 90 100 110
pF1KB6 ----LRVFRNQ---LPRKNDFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCLGPKT
.:::.: .:... . ... ..:. : :: ::.
NP_115 GARSWKVFRSQCLQVPEREA----QDAQKQGNSLAAEDWC----EGADDWGSDTEEGPSP
90 100 110 120 130 140
120 130 140 150 160 170
pF1KB6 CSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLD--HIIPDHNFLFPEFEIVIETEDEIM
. :. . .:: .. : : : .: :: . : . ::.
NP_115 QFTLDFGNDASSA-KDVDWTARLQDLRLQDAVLGAAHPVPPGLPLFLPYYICVADEDDYR
150 160 170 180 190
180 190 200 210
pF1KB6 PEVVEKE------DYSEIIG-SMGEALEEEL--DSMAKHESR----EDKIFQKFKTQIAL
: . ::.. : .: . : . : :. :.:. :. : :: .::
NP_115 DFVNLDHAHSLLRDYQQREGIAMDQLLSQSLPNDGDEKYEKTIIKSGDQTFYKFMKRIAA
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB6 EPEQILRYGRGIAPIWISGENIPQEKDIPDCP-CGAKRILEFQVMPQLLNYLKADRLGKS
::::::. . :.... . . ..: : ::..::.:::.:: :...::. :: :
NP_115 CQEQILRYSWSGEPLFLTCPT-SEVTELPACSQCGGQRIFEFQLMPALVSMLKSANLGLS
260 270 280 290 300 310
280 290 300 310
pF1KB6 IDWGILAVFTCAESCSLGTGYT--EEFVWKQDVTDTP
...: . :.:: .:: . : ::: :. :
NP_115 VEFGTILVYTCEKSCWPPNHQTPMEEFCIIQEDPDELLFK
320 330 340 350
>>XP_005273224 (OMIM: 606425,609070,609820) PREDICTED: e (345 aa)
initn: 135 init1: 115 opt: 150 Z-score: 170.2 bits: 39.8 E(85289): 0.0097
Smith-Waterman score: 150; 37.9% identity (60.3% similar) in 58 aa overlap (102-157:21-77)
80 90 100 110 120 130
pF1KB6 DFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCL-GPKTCSRCHKAYYCSKEHQTLD
:..:: . . ::::....:: :::: :
XP_005 MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQD
10 20 30 40 50
140 150 160 170 180
pF1KB6 WRLGHKQACAQPDH-LDHIIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYSEIIGSMGEA
:. :: .: . : : . :. :
XP_005 WK-KHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNASGDAAK
60 70 80 90 100
311 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:28:54 2016 done: Sat Nov 5 21:28:56 2016
Total Scan time: 8.190 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]