FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6437, 313 aa 1>>>pF1KB6437 313 - 313 aa - 313 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9365+/-0.00122; mu= 6.7785+/- 0.072 mean_var=104.2574+/-22.153, 0's: 0 Z-trim(104.8): 240 B-trim: 243 in 2/49 Lambda= 0.125609 statistics sampled from 7829 (8105) to 7829 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.249), width: 16 Scan time: 2.580 The best scores are: opt bits E(32554) CCDS4020.1 ANKRA2 gene_id:57763|Hs108|chr5 ( 313) 2056 383.5 1.1e-106 CCDS12395.1 RFXANK gene_id:8625|Hs108|chr19 ( 260) 795 155.0 5.8e-38 CCDS62611.1 RFXANK gene_id:8625|Hs108|chr19 ( 238) 650 128.7 4.4e-30 CCDS12396.1 RFXANK gene_id:8625|Hs108|chr19 ( 237) 642 127.3 1.2e-29 >>CCDS4020.1 ANKRA2 gene_id:57763|Hs108|chr5 (313 aa) initn: 2056 init1: 2056 opt: 2056 Z-score: 2028.7 bits: 383.5 E(32554): 1.1e-106 Smith-Waterman score: 2056; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313) 10 20 30 40 50 60 pF1KB6 MDTSTNLDIGAQLIVEECPSTYSLTGMPDIKIEHPLDPNSEEGSAQGVAMGMKFILPNRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 MDTSTNLDIGAQLIVEECPSTYSLTGMPDIKIEHPLDPNSEEGSAQGVAMGMKFILPNRF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DMNVCSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIHTSPSPGIQVRHVYTPSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 DMNVCSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIHTSPSPGIQVRHVYTPSTT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KHFSPIKQSTTLTNKHRGNEVSTTPLLANSLSVHQLAAQGEMLYLATRIEQENVINHTDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 KHFSPIKQSTTLTNKHRGNEVSTTPLLANSLSVHQLAAQGEMLYLATRIEQENVINHTDE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 EGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGKGRESALSLACSKGYTDIVKMLLDCGVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 EGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGKGRESALSLACSKGYTDIVKMLLDCGVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 VNEYDWNGGTPLLYAVHGNHVKCVKMLLESGADPTIETDSGYNSMDLAVALGYRSVQQVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 VNEYDWNGGTPLLYAVHGNHVKCVKMLLESGADPTIETDSGYNSMDLAVALGYRSVQQVI 250 260 270 280 290 300 310 pF1KB6 ESHLLKLLQNIKE ::::::::::::: CCDS40 ESHLLKLLQNIKE 310 >>CCDS12395.1 RFXANK gene_id:8625|Hs108|chr19 (260 aa) initn: 872 init1: 613 opt: 795 Z-score: 795.0 bits: 155.0 E(32554): 5.8e-38 Smith-Waterman score: 795; 58.6% identity (78.9% similar) in 227 aa overlap (86-310:35-252) 60 70 80 90 100 110 pF1KB6 LPNRFDMNVCSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIH-TSPSPGIQVRHV :: : : :: :. . ..: : .: CCDS12 QPAEDLIQTQQTPASELGDPEDPGEEAADGSDTVVLS-LFP--CTPEPVNPEPDASV--- 10 20 30 40 50 120 130 140 150 160 170 pF1KB6 YTPSTTKHFSPIKQSTTLTNKHRGNEVSTTPLLANSLSVHQLAAQGEMLYLATRIEQ-EN :. . : .:.::::::..::::::. : .:::.::::::::. : .... .: CCDS12 ---SSPQAGSSLKHSTTLTNRQRGNEVSALPATLDSLSIHQLAAQGELDQLKEHLRKGDN 60 70 80 90 100 110 180 190 200 210 220 230 pF1KB6 VINHTDEEGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGKGRESALSLACSKGYTDIVKM ..:. ::.:::::.::.: :.: .:.:::. ::::..:.: :::::::: . :::::: . CCDS12 LVNKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVGL 120 130 140 150 160 170 240 250 260 270 280 290 pF1KB6 LLDCGVDVNEYDWNGGTPLLYAVHGNHVKCVKMLLESGADPTIETDSGYNSMDLAVALGY ::. ::.: :::::::::::::.:::::::. :: ::: : :.::::. ::::::::: CCDS12 LLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGY 180 190 200 210 220 230 300 310 pF1KB6 RSVQQVIESHLLKLLQNIKE :.::::::.:.:::.:. CCDS12 RKVQQVIENHILKLFQSNLVPADPE 240 250 260 >>CCDS62611.1 RFXANK gene_id:8625|Hs108|chr19 (238 aa) initn: 801 init1: 613 opt: 650 Z-score: 653.6 bits: 128.7 E(32554): 4.4e-30 Smith-Waterman score: 682; 54.4% identity (72.6% similar) in 226 aa overlap (86-310:35-230) 60 70 80 90 100 110 pF1KB6 LPNRFDMNVCSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIH-TSPSPGIQVRHV :: : : :: :. . ..: : .: CCDS62 QPAEDLIQTQQTPASELGDPEDPGEEAADGSDTVVLS-LFP--CTPEPVNPEPDASV--- 10 20 30 40 50 120 130 140 150 160 170 pF1KB6 YTPSTTKHFSPIKQSTTLTNKHRGNEVSTTPLLANSLSVHQLAAQGEMLYLATRIEQENV :. . : .:.::::::..::::::. : :: .. .:. CCDS62 ---SSPQAGSSLKHSTTLTNRQRGNEVSALP--------------------AT-LDCDNL 60 70 80 90 180 190 200 210 220 230 pF1KB6 INHTDEEGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGKGRESALSLACSKGYTDIVKML .:. ::.:::::.::.: :.: .:.:::. ::::..:.: :::::::: . :::::: .: CCDS62 VNKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVGLL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB6 LDCGVDVNEYDWNGGTPLLYAVHGNHVKCVKMLLESGADPTIETDSGYNSMDLAVALGYR :. ::.: :::::::::::::.:::::::. :: ::: : :.::::. :::::::::: CCDS62 LERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYR 160 170 180 190 200 210 300 310 pF1KB6 SVQQVIESHLLKLLQNIKE .::::::.:.:::.:. CCDS62 KVQQVIENHILKLFQSNLVPADPE 220 230 >>CCDS12396.1 RFXANK gene_id:8625|Hs108|chr19 (237 aa) initn: 831 init1: 613 opt: 642 Z-score: 645.8 bits: 127.3 E(32554): 1.2e-29 Smith-Waterman score: 678; 59.9% identity (78.1% similar) in 187 aa overlap (124-310:64-229) 100 110 120 130 140 150 pF1KB6 LFKAECNIHTSPSPGIQVRHVYTPSTTKHFSPIKQSTTLTNKHRGNEVSTTPLLANSLSV : .:.::::::..::::::. : CCDS12 GSDTVVLSLFPCTPEPVNPEPDASVSSPQGSSLKHSTTLTNRQRGNEVSALP-------- 40 50 60 70 80 160 170 180 190 200 210 pF1KB6 HQLAAQGEMLYLATRIEQENVINHTDEEGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGK :: .. .:..:. ::.:::::.::.: :.: .:.:::. ::::..:.: CCDS12 ------------AT-LDCDNLVNKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAK 90 100 110 120 130 220 230 240 250 260 270 pF1KB6 GRESALSLACSKGYTDIVKMLLDCGVDVNEYDWNGGTPLLYAVHGNHVKCVKMLLESGAD :::::::: . :::::: .::. ::.: :::::::::::::.:::::::. :: ::: CCDS12 ERESALSLASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGAD 140 150 160 170 180 190 280 290 300 310 pF1KB6 PTIETDSGYNSMDLAVALGYRSVQQVIESHLLKLLQNIKE : :.::::. ::::::::::.::::::.:.:::.:. CCDS12 LTTEADSGYTPMDLAVALGYRKVQQVIENHILKLFQSNLVPADPE 200 210 220 230 313 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:16:26 2016 done: Sat Nov 5 08:16:27 2016 Total Scan time: 2.580 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]