Result of FASTA (omim) for
pF1KB6438
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6438, 340 aa
1>>>pF1KB6438 340 - 340 aa - 340 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4794+/-0.000331; mu= 17.1801+/- 0.020
mean_var=100.7394+/-20.558, 0's: 0 Z-trim(119.0): 231 B-trim: 1482 in 2/49
Lambda= 0.127783
statistics sampled from 32126 (32472) to 32126 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.381), width: 16
Scan time: 8.010
The best scores are: opt bits E(85289)
NP_009113 (OMIM: 211980,605082) ras association do ( 340) 2348 442.8 4.8e-124
NP_733832 (OMIM: 211980,605082) ras association do ( 344) 2320 437.7 1.7e-122
NP_733831 (OMIM: 211980,605082) ras association do ( 270) 1463 279.6 5.3e-75
XP_011531617 (OMIM: 211980,605082) PREDICTED: ras ( 270) 1463 279.6 5.3e-75
NP_733830 (OMIM: 211980,605082) ras association do ( 189) 1251 240.4 2.4e-63
XP_011531618 (OMIM: 211980,605082) PREDICTED: ras ( 189) 1251 240.4 2.4e-63
NP_001193886 (OMIM: 211980,605082) ras association ( 189) 1251 240.4 2.4e-63
NP_872604 (OMIM: 607020) ras association domain-co ( 418) 942 183.7 5.9e-46
NP_872606 (OMIM: 607020) ras association domain-co ( 265) 754 148.9 1.2e-35
NP_872605 (OMIM: 607020) ras association domain-co ( 336) 628 125.8 1.4e-28
XP_016874671 (OMIM: 607019) PREDICTED: ras associa ( 211) 430 89.1 9.5e-18
XP_011536497 (OMIM: 607019) PREDICTED: ras associa ( 226) 430 89.1 1e-17
XP_006719408 (OMIM: 607019) PREDICTED: ras associa ( 228) 430 89.1 1e-17
NP_835463 (OMIM: 607019) ras association domain-co ( 238) 430 89.1 1e-17
XP_016872247 (OMIM: 610559) PREDICTED: ras associa ( 185) 204 47.3 3e-05
XP_011538557 (OMIM: 610559) PREDICTED: ras associa ( 185) 204 47.3 3e-05
XP_016872245 (OMIM: 610559) PREDICTED: ras associa ( 185) 204 47.3 3e-05
XP_016872246 (OMIM: 610559) PREDICTED: ras associa ( 185) 204 47.3 3e-05
XP_005271892 (OMIM: 610559) PREDICTED: ras associa ( 259) 204 47.5 3.8e-05
NP_114412 (OMIM: 610559) ras association domain-co ( 321) 204 47.6 4.4e-05
XP_005271890 (OMIM: 610559) PREDICTED: ras associa ( 348) 204 47.6 4.7e-05
XP_006718077 (OMIM: 610559) PREDICTED: ras associa ( 352) 204 47.6 4.7e-05
XP_006718076 (OMIM: 610559) PREDICTED: ras associa ( 363) 204 47.6 4.8e-05
XP_016872244 (OMIM: 610559) PREDICTED: ras associa ( 379) 204 47.6 5e-05
XP_016872243 (OMIM: 610559) PREDICTED: ras associa ( 394) 204 47.7 5.1e-05
XP_016883640 (OMIM: 609492) PREDICTED: ras associa ( 326) 195 45.9 0.00014
XP_016883642 (OMIM: 609492) PREDICTED: ras associa ( 326) 195 45.9 0.00014
XP_005260952 (OMIM: 609492) PREDICTED: ras associa ( 326) 195 45.9 0.00014
NP_055552 (OMIM: 609492) ras association domain-co ( 326) 195 45.9 0.00014
NP_739580 (OMIM: 609492) ras association domain-co ( 326) 195 45.9 0.00014
XP_016883641 (OMIM: 609492) PREDICTED: ras associa ( 326) 195 45.9 0.00014
XP_016883639 (OMIM: 609492) PREDICTED: ras associa ( 326) 195 45.9 0.00014
XP_011527714 (OMIM: 609492) PREDICTED: ras associa ( 328) 195 45.9 0.00014
XP_016883638 (OMIM: 609492) PREDICTED: ras associa ( 328) 195 45.9 0.00014
XP_011527713 (OMIM: 609492) PREDICTED: ras associa ( 328) 195 45.9 0.00014
XP_011527712 (OMIM: 609492) PREDICTED: ras associa ( 328) 195 45.9 0.00014
XP_016863326 (OMIM: 612620) PREDICTED: ras associa ( 241) 191 45.1 0.00019
XP_016857292 (OMIM: 176982) PREDICTED: protein kin ( 358) 193 45.6 0.0002
XP_016877349 (OMIM: 603962) PREDICTED: RAS guanyl- ( 749) 197 46.6 0.0002
NP_001122074 (OMIM: 603962) RAS guanyl-releasing p ( 762) 197 46.7 0.0002
NP_005730 (OMIM: 603962) RAS guanyl-releasing prot ( 797) 197 46.7 0.00021
XP_011529992 (OMIM: 612620) PREDICTED: ras associa ( 279) 191 45.1 0.00021
XP_011529993 (OMIM: 612620) PREDICTED: ras associa ( 279) 191 45.1 0.00021
NP_002731 (OMIM: 600539) protein kinase C iota typ ( 596) 195 46.2 0.00022
XP_011540077 (OMIM: 176982) PREDICTED: protein kin ( 416) 193 45.7 0.00022
NP_001257321 (OMIM: 612620) ras association domain ( 325) 191 45.2 0.00024
NP_803876 (OMIM: 612620) ras association domain-co ( 337) 191 45.2 0.00024
XP_011529990 (OMIM: 612620) PREDICTED: ras associa ( 337) 191 45.2 0.00024
NP_001229803 (OMIM: 176982) protein kinase C zeta ( 488) 193 45.7 0.00024
XP_011540076 (OMIM: 176982) PREDICTED: protein kin ( 491) 193 45.7 0.00024
>>NP_009113 (OMIM: 211980,605082) ras association domain (340 aa)
initn: 2348 init1: 2348 opt: 2348 Z-score: 2348.0 bits: 442.8 E(85289): 4.8e-124
Smith-Waterman score: 2348; 100.0% identity (100.0% similar) in 340 aa overlap (1-340:1-340)
10 20 30 40 50 60
pF1KB6 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 THTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRCRALVCLDCCGPRDLGWEPAVERDTNVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 THTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRCRALVCLDCCGPRDLGWEPAVERDTNVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 KPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 KFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPE
250 260 270 280 290 300
310 320 330 340
pF1KB6 LHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
::::::::::::::::::::::::::::::::::::::::
NP_009 LHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
310 320 330 340
>>NP_733832 (OMIM: 211980,605082) ras association domain (344 aa)
initn: 1749 init1: 1749 opt: 2320 Z-score: 2320.0 bits: 437.7 E(85289): 1.7e-122
Smith-Waterman score: 2320; 98.5% identity (98.8% similar) in 344 aa overlap (1-340:1-344)
10 20 30 40 50 60
pF1KB6 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 THTWCDLCGDFIWGVVRKGLQCAH----CKFTCHYRCRALVCLDCCGPRDLGWEPAVERD
:::::::::::::::::::::::. ::::::::::::::::::::::::::::::::
NP_733 THTWCDLCGDFIWGVVRKGLQCARLSADCKFTCHYRCRALVCLDCCGPRDLGWEPAVERD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 TNVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 TNVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 PSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 PSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 DDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 DDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAF
250 260 270 280 290 300
300 310 320 330 340
pF1KB6 SMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
::::::::::::::::::::::::::::::::::::::::::::
NP_733 SMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
310 320 330 340
>>NP_733831 (OMIM: 211980,605082) ras association domain (270 aa)
initn: 1463 init1: 1463 opt: 1463 Z-score: 1467.5 bits: 279.6 E(85289): 5.3e-75
Smith-Waterman score: 1463; 100.0% identity (100.0% similar) in 221 aa overlap (120-340:50-270)
90 100 110 120 130 140
pF1KB6 HYRCRALVCLDCCGPRDLGWEPAVERDTNVDEPVEWETPDLSQAEIEQKIKEYNAQINSN
::::::::::::::::::::::::::::::
NP_733 GYCSQEDSDSELEQYFTARTSLARRPRRDQDEPVEWETPDLSQAEIEQKIKEYNAQINSN
20 30 40 50 60 70
150 160 170 180 190 200
pF1KB6 LFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 LFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKD
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB6 AVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 AVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLR
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB6 LLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 LLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQK
200 210 220 230 240 250
330 340
pF1KB6 IQEALHACPLG
:::::::::::
NP_733 IQEALHACPLG
260 270
>>XP_011531617 (OMIM: 211980,605082) PREDICTED: ras asso (270 aa)
initn: 1463 init1: 1463 opt: 1463 Z-score: 1467.5 bits: 279.6 E(85289): 5.3e-75
Smith-Waterman score: 1463; 100.0% identity (100.0% similar) in 221 aa overlap (120-340:50-270)
90 100 110 120 130 140
pF1KB6 HYRCRALVCLDCCGPRDLGWEPAVERDTNVDEPVEWETPDLSQAEIEQKIKEYNAQINSN
::::::::::::::::::::::::::::::
XP_011 GYCSQEDSDSELEQYFTARTSLARRPRRDQDEPVEWETPDLSQAEIEQKIKEYNAQINSN
20 30 40 50 60 70
150 160 170 180 190 200
pF1KB6 LFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKD
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB6 AVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLR
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB6 LLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQK
200 210 220 230 240 250
330 340
pF1KB6 IQEALHACPLG
:::::::::::
XP_011 IQEALHACPLG
260 270
>>NP_733830 (OMIM: 211980,605082) ras association domain (189 aa)
initn: 1251 init1: 1251 opt: 1251 Z-score: 1258.2 bits: 240.4 E(85289): 2.4e-63
Smith-Waterman score: 1251; 100.0% identity (100.0% similar) in 189 aa overlap (152-340:1-189)
130 140 150 160 170 180
pF1KB6 PVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKK
::::::::::::::::::::::::::::::
NP_733 MSLNKDGSYTGFIKVQLKLVRPVSVPSSKK
10 20 30
190 200 210 220 230 240
pF1KB6 PPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 PPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRK
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB6 FALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 FALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPEL
100 110 120 130 140 150
310 320 330 340
pF1KB6 HNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
:::::::::::::::::::::::::::::::::::::::
NP_733 HNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
160 170 180
>>XP_011531618 (OMIM: 211980,605082) PREDICTED: ras asso (189 aa)
initn: 1251 init1: 1251 opt: 1251 Z-score: 1258.2 bits: 240.4 E(85289): 2.4e-63
Smith-Waterman score: 1251; 100.0% identity (100.0% similar) in 189 aa overlap (152-340:1-189)
130 140 150 160 170 180
pF1KB6 PVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKK
::::::::::::::::::::::::::::::
XP_011 MSLNKDGSYTGFIKVQLKLVRPVSVPSSKK
10 20 30
190 200 210 220 230 240
pF1KB6 PPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRK
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB6 FALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPEL
100 110 120 130 140 150
310 320 330 340
pF1KB6 HNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
:::::::::::::::::::::::::::::::::::::::
XP_011 HNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
160 170 180
>>NP_001193886 (OMIM: 211980,605082) ras association dom (189 aa)
initn: 1251 init1: 1251 opt: 1251 Z-score: 1258.2 bits: 240.4 E(85289): 2.4e-63
Smith-Waterman score: 1251; 100.0% identity (100.0% similar) in 189 aa overlap (152-340:1-189)
130 140 150 160 170 180
pF1KB6 PVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKK
::::::::::::::::::::::::::::::
NP_001 MSLNKDGSYTGFIKVQLKLVRPVSVPSSKK
10 20 30
190 200 210 220 230 240
pF1KB6 PPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRK
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB6 FALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPEL
100 110 120 130 140 150
310 320 330 340
pF1KB6 HNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
:::::::::::::::::::::::::::::::::::::::
NP_001 HNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
160 170 180
>>NP_872604 (OMIM: 607020) ras association domain-contai (418 aa)
initn: 928 init1: 754 opt: 942 Z-score: 946.0 bits: 183.7 E(85289): 5.9e-46
Smith-Waterman score: 942; 47.3% identity (71.6% similar) in 338 aa overlap (11-334:81-410)
10 20 30 40
pF1KB6 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTAC
: : : : . : : : : .:.
NP_872 STAPGAREGRSARRAARGNLEPPPRASRPARPLRP-GLQQRLRRR-PGAPRPRDVRSIFE
60 70 80 90 100
50 60 70 80 90
pF1KB6 NPTRQLVP---GRGHRFQ----PAGPATHTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRC
.: :: :.:: : :.::. :::::: :.:..:.:..:::::: .:
NP_872 QPQDPRVPAERGEGHCFAELVLPGGPG---WCDLCGRE---VLRQALRCTNCKFTCHPEC
110 120 130 140 150 160
100 110 120 130 140
pF1KB6 RALVCLDCCGPRDLGWE-PAVER------DTNVDEPVEWETPDLSQAEIEQKIKEYNAQI
:.:. ::: . :. . :. : . :: .::: . ::.::: ::..
NP_872 RSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTRE
170 180 190 200 210 220
150 160 170 180 190 200
pF1KB6 NSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYL
.. : :.:..::.:::::::.::: :::.::.. .: :. :: . . .... .::::::
NP_872 KNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYL
230 240 250 260 270 280
210 220 230 240 250 260
pF1KB6 PKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPL
: ::.:.::. : : . :::..::.::.:::.:.:::::.: .. ::: ..:: ..::
NP_872 PLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPL
290 300 310 320 330 340
270 280 290 300 310 320
pF1KB6 RLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYC
:::::::. ..::::::::..:::.:::::.:::.::: ::..::.....:. .::.
NP_872 YLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKF
350 360 370 380 390 400
330 340
pF1KB6 RQKIQEALHACPLG
:::..:::
NP_872 RQKLEEALRESQGKPG
410
>>NP_872606 (OMIM: 607020) ras association domain-contai (265 aa)
initn: 754 init1: 754 opt: 754 Z-score: 761.2 bits: 148.9 E(85289): 1.2e-35
Smith-Waterman score: 754; 53.5% identity (81.6% similar) in 217 aa overlap (118-334:41-257)
90 100 110 120 130 140
pF1KB6 TCHYRCRALVCLDCCGPRDLGWEPAVERDTNVDEPVEWETPDLSQAEIEQKIKEYNAQIN
:: .::: . ::.::: ::.. .
NP_872 YCSLDEELEDCFFTAKTTFFRNAQSKHLSKNVCKPVEETQRPPTLQEIKQKIDSYNTREK
20 30 40 50 60 70
150 160 170 180 190 200
pF1KB6 SNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLP
. : :.:..::.:::::::.::: :::.::.. .: :. :: . . .... .:::::::
NP_872 NCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLP
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB6 KDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLR
::.:.::. : : . :::..::.::.:::.:.:::::.: .. ::: ..:: ..::
NP_872 LDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLY
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB6 LRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCR
:::::::. ..::::::::..:::.:::::.:::.::: ::..::.....:. .::. :
NP_872 LRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFR
200 210 220 230 240 250
330 340
pF1KB6 QKIQEALHACPLG
::..:::
NP_872 QKLEEALRESQGKPG
260
>>NP_872605 (OMIM: 607020) ras association domain-contai (336 aa)
initn: 614 init1: 440 opt: 628 Z-score: 634.3 bits: 125.8 E(85289): 1.4e-28
Smith-Waterman score: 628; 44.8% identity (67.2% similar) in 259 aa overlap (11-254:81-330)
10 20 30 40
pF1KB6 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTAC
: : : : . : : : : .:.
NP_872 STAPGAREGRSARRAARGNLEPPPRASRPARPLRP-GLQQRLRRR-PGAPRPRDVRSIFE
60 70 80 90 100
50 60 70 80 90
pF1KB6 NPTRQLVP---GRGHRFQ----PAGPATHTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRC
.: :: :.:: : :.::. :::::: :.:..:.:..:::::: .:
NP_872 QPQDPRVPAERGEGHCFAELVLPGGPG---WCDLCGRE---VLRQALRCTNCKFTCHPEC
110 120 130 140 150 160
100 110 120 130 140
pF1KB6 RALVCLDCCGPRDLGWE-PAVER------DTNVDEPVEW-ETPDLSQAEIEQKIKEYNAQ
:.:. ::: . :. . :. : . :: .::: . : : ::.::: ::..
NP_872 RSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQ-EIKQKIDSYNTR
170 180 190 200 210 220
150 160 170 180 190 200
pF1KB6 INSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFY
.. : :.:..::.:::::::.::: :::.::.. .: :. :: . . .... .:::::
NP_872 EKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFY
230 240 250 260 270 280
210 220 230 240 250 260
pF1KB6 LPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQP
:: ::.:.::. : : . :::..::.::.:::.:.:::::.: .. :::
NP_872 LPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVGCLLHP
290 300 310 320 330
270 280 290 300 310 320
pF1KB6 LRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSY
340 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:43:41 2016 done: Fri Nov 4 16:43:42 2016
Total Scan time: 8.010 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]