FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6440, 345 aa 1>>>pF1KB6440 345 - 345 aa - 345 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6788+/-0.000332; mu= 15.5354+/- 0.021 mean_var=99.4799+/-19.604, 0's: 0 Z-trim(117.5): 183 B-trim: 0 in 0/54 Lambda= 0.128590 statistics sampled from 29414 (29618) to 29414 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.347), width: 16 Scan time: 8.060 The best scores are: opt bits E(85289) NP_000033 (OMIM: 138700) beta-2-glycoprotein 1 pre ( 345) 2474 469.1 6e-132 XP_005245495 (OMIM: 147050,173610) PREDICTED: P-se ( 790) 456 95.1 5.5e-19 XP_005245496 (OMIM: 147050,173610) PREDICTED: P-se ( 790) 456 95.1 5.5e-19 NP_002996 (OMIM: 147050,173610) P-selectin precurs ( 830) 456 95.1 5.7e-19 XP_005245493 (OMIM: 147050,173610) PREDICTED: P-se ( 830) 456 95.1 5.7e-19 XP_005245492 (OMIM: 147050,173610) PREDICTED: P-se ( 830) 456 95.1 5.7e-19 NP_000706 (OMIM: 120830) C4b-binding protein alpha ( 597) 431 90.4 1.1e-17 XP_005273309 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 431 90.4 1.1e-17 XP_005273308 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 431 90.4 1.1e-17 NP_000441 (OMIM: 131210,145500) E-selectin precurs ( 610) 427 89.6 1.9e-17 XP_005245497 (OMIM: 147050,173610) PREDICTED: P-se ( 768) 426 89.5 2.5e-17 NP_699197 (OMIM: 611691) sushi, von Willebrand fac (3571) 433 91.4 3.2e-17 XP_011533056 (OMIM: 608397) PREDICTED: CUB and sus (2238) 414 87.7 2.6e-16 XP_011533055 (OMIM: 608397) PREDICTED: CUB and sus (2595) 414 87.8 2.9e-16 XP_016869220 (OMIM: 608397) PREDICTED: CUB and sus (3327) 414 87.9 3.5e-16 XP_011533054 (OMIM: 608397) PREDICTED: CUB and sus (3549) 414 87.9 3.6e-16 NP_150094 (OMIM: 608397) CUB and sushi domain-cont (3564) 414 87.9 3.6e-16 NP_002104 (OMIM: 134371,235400,603075) complement ( 330) 388 82.1 1.8e-15 XP_011515117 (OMIM: 608399) PREDICTED: CUB and sus (2173) 391 83.4 4.9e-15 XP_016868501 (OMIM: 608399) PREDICTED: CUB and sus (3463) 391 83.6 6.9e-15 XP_016868500 (OMIM: 608399) PREDICTED: CUB and sus (3507) 391 83.6 6.9e-15 XP_016868499 (OMIM: 608399) PREDICTED: CUB and sus (3577) 391 83.6 7e-15 XP_011515118 (OMIM: 608399) PREDICTED: CUB and sus (3603) 391 83.6 7.1e-15 XP_016868498 (OMIM: 608399) PREDICTED: CUB and sus (3637) 391 83.6 7.1e-15 NP_937757 (OMIM: 608399) CUB and sushi domain-cont (3667) 391 83.6 7.2e-15 XP_016868497 (OMIM: 608399) PREDICTED: CUB and sus (3681) 391 83.6 7.2e-15 NP_937756 (OMIM: 608399) CUB and sushi domain-cont (3707) 391 83.6 7.2e-15 NP_443132 (OMIM: 608399) CUB and sushi domain-cont (3538) 387 82.9 1.2e-14 NP_000565 (OMIM: 125240,613793) complement decay-a ( 381) 370 78.9 2e-14 NP_001287833 (OMIM: 125240,613793) complement deca ( 384) 370 78.9 2.1e-14 XP_016855956 (OMIM: 125240,613793) PREDICTED: comp ( 412) 370 78.9 2.2e-14 NP_001287832 (OMIM: 125240,613793) complement deca ( 439) 370 78.9 2.3e-14 NP_001108224 (OMIM: 125240,613793) complement deca ( 440) 370 78.9 2.3e-14 NP_001287831 (OMIM: 125240,613793) complement deca ( 444) 370 78.9 2.3e-14 XP_011507586 (OMIM: 134580,613235) PREDICTED: coag ( 675) 371 79.3 2.7e-14 XP_011507588 (OMIM: 134580,613235) PREDICTED: coag ( 628) 369 78.9 3.3e-14 NP_001985 (OMIM: 134580,613235) coagulation factor ( 661) 369 78.9 3.5e-14 XP_011507585 (OMIM: 134580,613235) PREDICTED: coag ( 676) 369 78.9 3.5e-14 XP_016855679 (OMIM: 608398) PREDICTED: CUB and sus (3362) 378 81.2 3.6e-14 XP_016855678 (OMIM: 608398) PREDICTED: CUB and sus (3506) 378 81.2 3.7e-14 XP_016855683 (OMIM: 608398) PREDICTED: CUB and sus (3566) 378 81.2 3.7e-14 XP_016855677 (OMIM: 608398) PREDICTED: CUB and sus (3567) 378 81.2 3.7e-14 XP_016856798 (OMIM: 120920,612922) PREDICTED: memb ( 363) 365 77.9 3.8e-14 XP_016855676 (OMIM: 608398) PREDICTED: CUB and sus (3606) 378 81.2 3.8e-14 XP_016855674 (OMIM: 608398) PREDICTED: CUB and sus (3607) 378 81.2 3.8e-14 XP_016855675 (OMIM: 608398) PREDICTED: CUB and sus (3607) 378 81.2 3.8e-14 XP_011507866 (OMIM: 120920,612922) PREDICTED: memb ( 370) 365 77.9 3.8e-14 XP_016856799 (OMIM: 120920,612922) PREDICTED: memb ( 348) 363 77.5 4.7e-14 NP_758871 (OMIM: 120920,612922) membrane cofactor ( 355) 363 77.5 4.8e-14 XP_016856797 (OMIM: 120920,612922) PREDICTED: memb ( 378) 363 77.6 5e-14 >>NP_000033 (OMIM: 138700) beta-2-glycoprotein 1 precurs (345 aa) initn: 2474 init1: 2474 opt: 2474 Z-score: 2489.9 bits: 469.1 E(85289): 6e-132 Smith-Waterman score: 2474; 99.7% identity (100.0% similar) in 345 aa overlap (1-345:1-345) 10 20 30 40 50 60 pF1KB6 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 FGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 DGPEEIECTKLGNWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFC :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: NP_000 DGPEEIECTKLGNWSAMPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFC 250 260 270 280 290 300 310 320 330 340 pF1KB6 KNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC ::::::::::::::::::::::::::::::::::::::::::::: NP_000 KNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC 310 320 330 340 >>XP_005245495 (OMIM: 147050,173610) PREDICTED: P-select (790 aa) initn: 391 init1: 196 opt: 456 Z-score: 461.9 bits: 95.1 E(85289): 5.5e-19 Smith-Waterman score: 456; 30.8% identity (56.7% similar) in 263 aa overlap (13-264:318-572) 10 20 30 40 pF1KB6 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYE .:. :. . :.. .. : :: .: XP_005 CSFSCEEGFALVGPEVVQCTASGVWTAPAPVCK-AVQCQHLEAPSEGTMDCVHPLTAF-A 290 300 310 320 330 340 50 60 70 80 90 pF1KB6 PGEEITYSCKPGYVSRGGMRKFICPLTGLW--PINT---LKCTPRVCPFAGILENGAVRY : . :.::: :: . . : .: : :. : ..: : : : .. . XP_005 YGSSCKFECQPGYRVRG-LDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSP-SL 350 360 370 380 390 400 100 110 120 130 140 150 pF1KB6 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK .:.: .. :: : ::.: ::: ..: . :.:. ::: . : .:. : . . XP_005 RAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSH 410 420 430 440 450 460 160 170 180 190 200 210 pF1KB6 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP-ECREVKC-PFPSRPDNGF : .. :... : : . : ... : . :::...: ::. . : :. : :.:: XP_005 PFGAFR--YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS-PQNGT 470 480 490 500 510 520 220 230 240 250 260 270 pF1KB6 VNYPAKP--TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SCKLPVKKA .. ..: . ::. : : .::::.:::...::. : :. . : :.: .: XP_005 MTC-VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE 530 540 550 560 570 280 290 300 310 320 330 pF1KB6 TVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSS XP_005 QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG 580 590 600 610 620 630 >-- initn: 240 init1: 140 opt: 194 Z-score: 199.2 bits: 46.5 E(85289): 0.00023 Smith-Waterman score: 215; 27.9% identity (55.2% similar) in 154 aa overlap (109-256:167-314) 80 90 100 110 120 130 pF1KB6 CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNT-GFYLNGADSAKCT-EEGKWSPELPV ::. : :. . :. : ..:: XP_005 KSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPE--- 140 150 160 170 180 190 140 150 160 170 180 190 pF1KB6 CAPII-CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT : . : .: . . .: :: : . . :.: . . : . . : . : :: XP_005 CEYVRECGELELPQHVLMNCSHP-LGNFS-FNSQCSFHCTDGYQVNGPSKLECLASGIWT 200 210 220 230 240 250 200 210 220 230 240 250 pF1KB6 -KLPECREVKCPFPSRPDNGFVN--YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLG : :.: ..:: . :. : .. . :: .. .... .:.:..:..: ::: ..:: : XP_005 NKPPQCLAAQCPPLKIPERGNMTCLHSAK-AFQHQSSCSFSCEEGFALVGPEVVQCTASG 260 270 280 290 300 310 260 270 280 290 300 310 pF1KB6 NWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTED :.: XP_005 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 320 330 340 350 360 370 >>XP_005245496 (OMIM: 147050,173610) PREDICTED: P-select (790 aa) initn: 391 init1: 196 opt: 456 Z-score: 461.9 bits: 95.1 E(85289): 5.5e-19 Smith-Waterman score: 456; 30.8% identity (56.7% similar) in 263 aa overlap (13-264:318-572) 10 20 30 40 pF1KB6 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYE .:. :. . :.. .. : :: .: XP_005 CSFSCEEGFALVGPEVVQCTASGVWTAPAPVCK-AVQCQHLEAPSEGTMDCVHPLTAF-A 290 300 310 320 330 340 50 60 70 80 90 pF1KB6 PGEEITYSCKPGYVSRGGMRKFICPLTGLW--PINT---LKCTPRVCPFAGILENGAVRY : . :.::: :: . . : .: : :. : ..: : : : .. . XP_005 YGSSCKFECQPGYRVRG-LDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSP-SL 350 360 370 380 390 400 100 110 120 130 140 150 pF1KB6 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK .:.: .. :: : ::.: ::: ..: . :.:. ::: . : .:. : . . XP_005 RAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSH 410 420 430 440 450 460 160 170 180 190 200 210 pF1KB6 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP-ECREVKC-PFPSRPDNGF : .. :... : : . : ... : . :::...: ::. . : :. : :.:: XP_005 PFGAFR--YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS-PQNGT 470 480 490 500 510 520 220 230 240 250 260 270 pF1KB6 VNYPAKP--TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SCKLPVKKA .. ..: . ::. : : .::::.:::...::. : :. . : :.: .: XP_005 MTC-VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE 530 540 550 560 570 280 290 300 310 320 330 pF1KB6 TVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSS XP_005 QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG 580 590 600 610 620 630 >-- initn: 240 init1: 140 opt: 194 Z-score: 199.2 bits: 46.5 E(85289): 0.00023 Smith-Waterman score: 215; 27.9% identity (55.2% similar) in 154 aa overlap (109-256:167-314) 80 90 100 110 120 130 pF1KB6 CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNT-GFYLNGADSAKCT-EEGKWSPELPV ::. : :. . :. : ..:: XP_005 KSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPE--- 140 150 160 170 180 190 140 150 160 170 180 190 pF1KB6 CAPII-CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT : . : .: . . .: :: : . . :.: . . : . . : . : :: XP_005 CEYVRECGELELPQHVLMNCSHP-LGNFS-FNSQCSFHCTDGYQVNGPSKLECLASGIWT 200 210 220 230 240 250 200 210 220 230 240 250 pF1KB6 -KLPECREVKCPFPSRPDNGFVN--YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLG : :.: ..:: . :. : .. . :: .. .... .:.:..:..: ::: ..:: : XP_005 NKPPQCLAAQCPPLKIPERGNMTCLHSAK-AFQHQSSCSFSCEEGFALVGPEVVQCTASG 260 270 280 290 300 310 260 270 280 290 300 310 pF1KB6 NWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTED :.: XP_005 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 320 330 340 350 360 370 >>NP_002996 (OMIM: 147050,173610) P-selectin precursor [ (830 aa) initn: 391 init1: 196 opt: 456 Z-score: 461.6 bits: 95.1 E(85289): 5.7e-19 Smith-Waterman score: 456; 30.8% identity (56.7% similar) in 263 aa overlap (13-264:318-572) 10 20 30 40 pF1KB6 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYE .:. :. . :.. .. : :: .: NP_002 CSFSCEEGFALVGPEVVQCTASGVWTAPAPVCK-AVQCQHLEAPSEGTMDCVHPLTAF-A 290 300 310 320 330 340 50 60 70 80 90 pF1KB6 PGEEITYSCKPGYVSRGGMRKFICPLTGLW--PINT---LKCTPRVCPFAGILENGAVRY : . :.::: :: . . : .: : :. : ..: : : : .. . NP_002 YGSSCKFECQPGYRVRG-LDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSP-SL 350 360 370 380 390 400 100 110 120 130 140 150 pF1KB6 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK .:.: .. :: : ::.: ::: ..: . :.:. ::: . : .:. : . . NP_002 RAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSH 410 420 430 440 450 460 160 170 180 190 200 210 pF1KB6 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP-ECREVKC-PFPSRPDNGF : .. :... : : . : ... : . :::...: ::. . : :. : :.:: NP_002 PFGAFR--YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS-PQNGT 470 480 490 500 510 520 220 230 240 250 260 270 pF1KB6 VNYPAKP--TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SCKLPVKKA .. ..: . ::. : : .::::.:::...::. : :. . : :.: .: NP_002 MTC-VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE 530 540 550 560 570 280 290 300 310 320 330 pF1KB6 TVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSS NP_002 QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG 580 590 600 610 620 630 >-- initn: 240 init1: 140 opt: 194 Z-score: 198.9 bits: 46.5 E(85289): 0.00024 Smith-Waterman score: 215; 27.9% identity (55.2% similar) in 154 aa overlap (109-256:167-314) 80 90 100 110 120 130 pF1KB6 CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNT-GFYLNGADSAKCT-EEGKWSPELPV ::. : :. . :. : ..:: NP_002 KSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPE--- 140 150 160 170 180 190 140 150 160 170 180 190 pF1KB6 CAPII-CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT : . : .: . . .: :: : . . :.: . . : . . : . : :: NP_002 CEYVRECGELELPQHVLMNCSHP-LGNFS-FNSQCSFHCTDGYQVNGPSKLECLASGIWT 200 210 220 230 240 250 200 210 220 230 240 250 pF1KB6 -KLPECREVKCPFPSRPDNGFVN--YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLG : :.: ..:: . :. : .. . :: .. .... .:.:..:..: ::: ..:: : NP_002 NKPPQCLAAQCPPLKIPERGNMTCLHSAK-AFQHQSSCSFSCEEGFALVGPEVVQCTASG 260 270 280 290 300 310 260 270 280 290 300 310 pF1KB6 NWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTED :.: NP_002 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 320 330 340 350 360 370 >>XP_005245493 (OMIM: 147050,173610) PREDICTED: P-select (830 aa) initn: 391 init1: 196 opt: 456 Z-score: 461.6 bits: 95.1 E(85289): 5.7e-19 Smith-Waterman score: 456; 30.8% identity (56.7% similar) in 263 aa overlap (13-264:318-572) 10 20 30 40 pF1KB6 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYE .:. :. . :.. .. : :: .: XP_005 CSFSCEEGFALVGPEVVQCTASGVWTAPAPVCK-AVQCQHLEAPSEGTMDCVHPLTAF-A 290 300 310 320 330 340 50 60 70 80 90 pF1KB6 PGEEITYSCKPGYVSRGGMRKFICPLTGLW--PINT---LKCTPRVCPFAGILENGAVRY : . :.::: :: . . : .: : :. : ..: : : : .. . XP_005 YGSSCKFECQPGYRVRG-LDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSP-SL 350 360 370 380 390 400 100 110 120 130 140 150 pF1KB6 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK .:.: .. :: : ::.: ::: ..: . :.:. ::: . : .:. : . . XP_005 RAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSH 410 420 430 440 450 460 160 170 180 190 200 210 pF1KB6 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP-ECREVKC-PFPSRPDNGF : .. :... : : . : ... : . :::...: ::. . : :. : :.:: XP_005 PFGAFR--YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS-PQNGT 470 480 490 500 510 520 220 230 240 250 260 270 pF1KB6 VNYPAKP--TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SCKLPVKKA .. ..: . ::. : : .::::.:::...::. : :. . : :.: .: XP_005 MTC-VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE 530 540 550 560 570 280 290 300 310 320 330 pF1KB6 TVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSS XP_005 QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG 580 590 600 610 620 630 >-- initn: 240 init1: 140 opt: 194 Z-score: 198.9 bits: 46.5 E(85289): 0.00024 Smith-Waterman score: 215; 27.9% identity (55.2% similar) in 154 aa overlap (109-256:167-314) 80 90 100 110 120 130 pF1KB6 CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNT-GFYLNGADSAKCT-EEGKWSPELPV ::. : :. . :. : ..:: XP_005 KSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPE--- 140 150 160 170 180 190 140 150 160 170 180 190 pF1KB6 CAPII-CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT : . : .: . . .: :: : . . :.: . . : . . : . : :: XP_005 CEYVRECGELELPQHVLMNCSHP-LGNFS-FNSQCSFHCTDGYQVNGPSKLECLASGIWT 200 210 220 230 240 250 200 210 220 230 240 250 pF1KB6 -KLPECREVKCPFPSRPDNGFVN--YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLG : :.: ..:: . :. : .. . :: .. .... .:.:..:..: ::: ..:: : XP_005 NKPPQCLAAQCPPLKIPERGNMTCLHSAK-AFQHQSSCSFSCEEGFALVGPEVVQCTASG 260 270 280 290 300 310 260 270 280 290 300 310 pF1KB6 NWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTED :.: XP_005 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 320 330 340 350 360 370 >>XP_005245492 (OMIM: 147050,173610) PREDICTED: P-select (830 aa) initn: 391 init1: 196 opt: 456 Z-score: 461.6 bits: 95.1 E(85289): 5.7e-19 Smith-Waterman score: 456; 30.8% identity (56.7% similar) in 263 aa overlap (13-264:318-572) 10 20 30 40 pF1KB6 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYE .:. :. . :.. .. : :: .: XP_005 CSFSCEEGFALVGPEVVQCTASGVWTAPAPVCK-AVQCQHLEAPSEGTMDCVHPLTAF-A 290 300 310 320 330 340 50 60 70 80 90 pF1KB6 PGEEITYSCKPGYVSRGGMRKFICPLTGLW--PINT---LKCTPRVCPFAGILENGAVRY : . :.::: :: . . : .: : :. : ..: : : : .. . XP_005 YGSSCKFECQPGYRVRG-LDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSP-SL 350 360 370 380 390 400 100 110 120 130 140 150 pF1KB6 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK .:.: .. :: : ::.: ::: ..: . :.:. ::: . : .:. : . . XP_005 RAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSH 410 420 430 440 450 460 160 170 180 190 200 210 pF1KB6 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP-ECREVKC-PFPSRPDNGF : .. :... : : . : ... : . :::...: ::. . : :. : :.:: XP_005 PFGAFR--YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS-PQNGT 470 480 490 500 510 520 220 230 240 250 260 270 pF1KB6 VNYPAKP--TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SCKLPVKKA .. ..: . ::. : : .::::.:::...::. : :. . : :.: .: XP_005 MTC-VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE 530 540 550 560 570 280 290 300 310 320 330 pF1KB6 TVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSS XP_005 QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG 580 590 600 610 620 630 >-- initn: 240 init1: 140 opt: 194 Z-score: 198.9 bits: 46.5 E(85289): 0.00024 Smith-Waterman score: 215; 27.9% identity (55.2% similar) in 154 aa overlap (109-256:167-314) 80 90 100 110 120 130 pF1KB6 CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNT-GFYLNGADSAKCT-EEGKWSPELPV ::. : :. . :. : ..:: XP_005 KSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPE--- 140 150 160 170 180 190 140 150 160 170 180 190 pF1KB6 CAPII-CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT : . : .: . . .: :: : . . :.: . . : . . : . : :: XP_005 CEYVRECGELELPQHVLMNCSHP-LGNFS-FNSQCSFHCTDGYQVNGPSKLECLASGIWT 200 210 220 230 240 250 200 210 220 230 240 250 pF1KB6 -KLPECREVKCPFPSRPDNGFVN--YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLG : :.: ..:: . :. : .. . :: .. .... .:.:..:..: ::: ..:: : XP_005 NKPPQCLAAQCPPLKIPERGNMTCLHSAK-AFQHQSSCSFSCEEGFALVGPEVVQCTASG 260 270 280 290 300 310 260 270 280 290 300 310 pF1KB6 NWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTED :.: XP_005 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 320 330 340 350 360 370 >>NP_000706 (OMIM: 120830) C4b-binding protein alpha cha (597 aa) initn: 285 init1: 120 opt: 431 Z-score: 438.4 bits: 90.4 E(85289): 1.1e-17 Smith-Waterman score: 431; 30.7% identity (53.7% similar) in 270 aa overlap (17-267:45-303) 10 20 30 40 pF1KB6 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPL---KTFYEP :. : .: : : :.. . . .: .. NP_000 RKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLG-NCGPPPTLSFAAPMDITLTETRFKT 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB6 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTT-FEY : . :.: :::: . . . : : : ::. : . : : :.:: :. : . . NP_000 GTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTF-CIYKRCRHPGELRNGQVEIKTDLSF 80 90 100 110 120 130 110 120 130 140 150 pF1KB6 PNTISFSCNTGFYLNGADSAKCTEEGK---WSPELPVCAPIIC-PPPSIPTFATLRVYKP . : :::. ::.: :. ...: . . :: :: : . : :::.: : . NP_000 GSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDI------RNGRH 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 SAGNNSL-YRDTAVFECLPQHAMFGNDTITCT----THGNWTKLPE-CREVKCPFPSRPD :. .: : .... : :. ...:. .:.:: : : : : :... : .:: NP_000 SGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITC---RKPD 190 200 210 220 230 240 220 230 240 250 260 pF1KB6 --NGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SC-KLP .: . : ::: .: :. :. : : :.: ..:. . :.:. :: .:: NP_000 VSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLP 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB6 VKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFK NP_000 DIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEAL 310 320 330 340 350 360 >-- initn: 159 init1: 96 opt: 286 Z-score: 293.0 bits: 63.5 E(85289): 1.4e-09 Smith-Waterman score: 286; 27.1% identity (49.2% similar) in 240 aa overlap (36-261:316-539) 10 20 30 40 50 60 pF1KB6 LILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKT-FYEPGEEITYSCKPGYV-SRGGMRK : : : : . : :.::: . NP_000 KWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTT 290 300 310 320 330 340 70 80 90 100 110 pF1KB6 FICPLTGLW-PINTLKCTPRVCPFAGILENGAVR---------YTTFEYPNTISFSCNTG :: . : : . : :: :.:: . . .. : . :::::. NP_000 VICQKNLRWTPYQ--GCEALCCP-EPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHET 350 360 370 380 390 400 120 130 140 150 160 170 pF1KB6 FYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFE . :: : .: :::. : :. : ::.: :: :. . :.... ..: NP_000 SRF----SAICQGDGTWSPRTPSCGDICNFPPKIAHGH----YKQSS-SYSFFKEEIIYE 410 420 430 440 450 180 190 200 210 220 230 pF1KB6 CLPQHAMFGNDTITCTTHGNWTK-LPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATF : . . :. ..:. ...:. :.:. . : : :: .. : ...:. NP_000 CDKGYILVGQAKLSCS-YSHWSAPAPQCKAL-CRKPELV-NGRLSVD-KDQYVEPENVTI 460 470 480 490 500 240 250 260 270 280 290 pF1KB6 GCHDGYSLDGPEEIECTKLGNW-SAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGML : .::.. ::. : :. .: .:.:. NP_000 QCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKRLMQCLPNPEDVKMAL 510 520 530 540 550 560 >>XP_005273309 (OMIM: 120830) PREDICTED: C4b-binding pro (597 aa) initn: 285 init1: 120 opt: 431 Z-score: 438.4 bits: 90.4 E(85289): 1.1e-17 Smith-Waterman score: 431; 30.7% identity (53.7% similar) in 270 aa overlap (17-267:45-303) 10 20 30 40 pF1KB6 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPL---KTFYEP :. : .: : : :.. . . .: .. XP_005 RKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLG-NCGPPPTLSFAAPMDITLTETRFKT 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB6 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTT-FEY : . :.: :::: . . . : : : ::. : . : : :.:: :. : . . XP_005 GTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTF-CIYKRCRHPGELRNGQVEIKTDLSF 80 90 100 110 120 130 110 120 130 140 150 pF1KB6 PNTISFSCNTGFYLNGADSAKCTEEGK---WSPELPVCAPIIC-PPPSIPTFATLRVYKP . : :::. ::.: :. ...: . . :: :: : . : :::.: : . XP_005 GSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDI------RNGRH 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 SAGNNSL-YRDTAVFECLPQHAMFGNDTITCT----THGNWTKLPE-CREVKCPFPSRPD :. .: : .... : :. ...:. .:.:: : : : : :... : .:: XP_005 SGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITC---RKPD 190 200 210 220 230 240 220 230 240 250 260 pF1KB6 --NGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SC-KLP .: . : ::: .: :. :. : : :.: ..:. . :.:. :: .:: XP_005 VSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLP 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB6 VKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFK XP_005 DIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEAL 310 320 330 340 350 360 >-- initn: 159 init1: 96 opt: 286 Z-score: 293.0 bits: 63.5 E(85289): 1.4e-09 Smith-Waterman score: 286; 27.1% identity (49.2% similar) in 240 aa overlap (36-261:316-539) 10 20 30 40 50 60 pF1KB6 LILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKT-FYEPGEEITYSCKPGYV-SRGGMRK : : : : . : :.::: . XP_005 KWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTT 290 300 310 320 330 340 70 80 90 100 110 pF1KB6 FICPLTGLW-PINTLKCTPRVCPFAGILENGAVR---------YTTFEYPNTISFSCNTG :: . : : . : :: :.:: . . .. : . :::::. XP_005 VICQKNLRWTPYQ--GCEALCCP-EPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHET 350 360 370 380 390 400 120 130 140 150 160 170 pF1KB6 FYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFE . :: : .: :::. : :. : ::.: :: :. . :.... ..: XP_005 SRF----SAICQGDGTWSPRTPSCGDICNFPPKIAHGH----YKQSS-SYSFFKEEIIYE 410 420 430 440 450 180 190 200 210 220 230 pF1KB6 CLPQHAMFGNDTITCTTHGNWTK-LPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATF : . . :. ..:. ...:. :.:. . : : :: .. : ...:. XP_005 CDKGYILVGQAKLSCS-YSHWSAPAPQCKAL-CRKPELV-NGRLSVD-KDQYVEPENVTI 460 470 480 490 500 240 250 260 270 280 290 pF1KB6 GCHDGYSLDGPEEIECTKLGNW-SAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGML : .::.. ::. : :. .: .:.:. XP_005 QCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKRLMQCLPNPEDVKMAL 510 520 530 540 550 560 >>XP_005273308 (OMIM: 120830) PREDICTED: C4b-binding pro (597 aa) initn: 285 init1: 120 opt: 431 Z-score: 438.4 bits: 90.4 E(85289): 1.1e-17 Smith-Waterman score: 431; 30.7% identity (53.7% similar) in 270 aa overlap (17-267:45-303) 10 20 30 40 pF1KB6 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPL---KTFYEP :. : .: : : :.. . . .: .. XP_005 RKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLG-NCGPPPTLSFAAPMDITLTETRFKT 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB6 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTT-FEY : . :.: :::: . . . : : : ::. : . : : :.:: :. : . . XP_005 GTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTF-CIYKRCRHPGELRNGQVEIKTDLSF 80 90 100 110 120 130 110 120 130 140 150 pF1KB6 PNTISFSCNTGFYLNGADSAKCTEEGK---WSPELPVCAPIIC-PPPSIPTFATLRVYKP . : :::. ::.: :. ...: . . :: :: : . : :::.: : . XP_005 GSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDI------RNGRH 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 SAGNNSL-YRDTAVFECLPQHAMFGNDTITCT----THGNWTKLPE-CREVKCPFPSRPD :. .: : .... : :. ...:. .:.:: : : : : :... : .:: XP_005 SGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITC---RKPD 190 200 210 220 230 240 220 230 240 250 260 pF1KB6 --NGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SC-KLP .: . : ::: .: :. :. : : :.: ..:. . :.:. :: .:: XP_005 VSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLP 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB6 VKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFK XP_005 DIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEAL 310 320 330 340 350 360 >-- initn: 159 init1: 96 opt: 286 Z-score: 293.0 bits: 63.5 E(85289): 1.4e-09 Smith-Waterman score: 286; 27.1% identity (49.2% similar) in 240 aa overlap (36-261:316-539) 10 20 30 40 50 60 pF1KB6 LILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKT-FYEPGEEITYSCKPGYV-SRGGMRK : : : : . : :.::: . XP_005 KWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTT 290 300 310 320 330 340 70 80 90 100 110 pF1KB6 FICPLTGLW-PINTLKCTPRVCPFAGILENGAVR---------YTTFEYPNTISFSCNTG :: . : : . : :: :.:: . . .. : . :::::. XP_005 VICQKNLRWTPYQ--GCEALCCP-EPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHET 350 360 370 380 390 400 120 130 140 150 160 170 pF1KB6 FYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFE . :: : .: :::. : :. : ::.: :: :. . :.... ..: XP_005 SRF----SAICQGDGTWSPRTPSCGDICNFPPKIAHGH----YKQSS-SYSFFKEEIIYE 410 420 430 440 450 180 190 200 210 220 230 pF1KB6 CLPQHAMFGNDTITCTTHGNWTK-LPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATF : . . :. ..:. ...:. :.:. . : : :: .. : ...:. XP_005 CDKGYILVGQAKLSCS-YSHWSAPAPQCKAL-CRKPELV-NGRLSVD-KDQYVEPENVTI 460 470 480 490 500 240 250 260 270 280 290 pF1KB6 GCHDGYSLDGPEEIECTKLGNW-SAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGML : .::.. ::. : :. .: .:.:. XP_005 QCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKRLMQCLPNPEDVKMAL 510 520 530 540 550 560 >>NP_000441 (OMIM: 131210,145500) E-selectin precursor [ (610 aa) initn: 454 init1: 158 opt: 427 Z-score: 434.3 bits: 89.6 E(85289): 1.9e-17 Smith-Waterman score: 427; 27.0% identity (54.8% similar) in 341 aa overlap (9-333:169-497) 10 20 30 pF1KB6 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLK ::.. :. . . .:. . :: NP_000 YTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLG 140 150 160 170 180 190 40 50 60 70 80 90 pF1KB6 TF-YEPGEEITYSCKPGYVSRGGMRKFICPLTGLW--PI---NTLKCTPRVCPFAGILEN .: :. . : :: ::. ..:. . : .: : :: :...: . : :..: NP_000 NFSYNSSCSI--SCDRGYLP-SSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 200 210 220 230 240 250 100 110 120 130 140 150 pF1KB6 GAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFAT .: . .: .:.:. :: : ::.: .:: :.:. : :.: . : : .. NP_000 FQ-NPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGS 260 270 280 290 300 310 160 170 180 190 200 210 pF1KB6 LRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTK-LPECREVKCPFPSRP .: . ::. . .... : : . : . :::.:.::. .: :. .: : : NP_000 VRCSHSPAGEFT-FKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNP 320 330 340 350 360 370 220 230 240 250 260 pF1KB6 DNGFVN-YP-AKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNW-SAMPSCKASCKLPV . :..: : :. .. : .. :.:..:. : : ....: :.: . :.:.: NP_000 ERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAV----- 380 390 400 410 420 270 280 290 300 310 320 pF1KB6 KKATVVYQGER--VKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDG---TIEVP . .:.: . :. .. . . . .. .: :.. . . :. .: . : ::: NP_000 -RCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQ-LECTSQGQWTEEVP 430 440 450 460 470 480 330 340 pF1KB6 KC-FKEHSSLAFWKTDASDVKPC .: . :::: NP_000 SCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPT 490 500 510 520 530 540 345 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:40:40 2016 done: Sat Nov 5 16:40:41 2016 Total Scan time: 8.060 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]