Result of FASTA (omim) for
pF1KB6441
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6441, 314 aa
1>>>pF1KB6441 314 - 314 aa - 314 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6982+/-0.000362; mu= 14.0766+/- 0.022
mean_var=80.6806+/-16.197, 0's: 0 Z-trim(114.1): 55 B-trim: 36 in 1/50
Lambda= 0.142787
statistics sampled from 23778 (23833) to 23778 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.279), width: 16
Scan time: 6.720
The best scores are: opt bits E(85289)
NP_001307604 (OMIM: 603292) BCL2/adenovirus E1B 19 ( 376) 2105 443.3 3.6e-124
NP_004321 (OMIM: 603292) BCL2/adenovirus E1B 19 kD ( 435) 2105 443.3 4.1e-124
NP_001307603 (OMIM: 603292) BCL2/adenovirus E1B 19 ( 447) 2006 422.9 5.8e-118
XP_016869847 (OMIM: 610691) PREDICTED: protein pru ( 337) 1150 246.5 5.5e-65
NP_001294978 (OMIM: 610691) protein prune homolog ( 337) 1150 246.5 5.5e-65
NP_001294979 (OMIM: 610691) protein prune homolog ( 352) 1146 245.7 1e-64
NP_001317609 (OMIM: 610691) protein prune homolog ( 353) 1142 244.9 1.8e-64
XP_016869843 (OMIM: 610691) PREDICTED: protein pru ( 365) 1137 243.9 3.8e-64
NP_001294980 (OMIM: 610691) protein prune homolog ( 324) 1136 243.6 4e-64
XP_016869848 (OMIM: 610691) PREDICTED: protein pru ( 336) 1136 243.6 4.1e-64
XP_016869845 (OMIM: 610691) PREDICTED: protein pru ( 352) 1136 243.7 4.2e-64
NP_056040 (OMIM: 610691) protein prune homolog 2 i (3088) 1146 246.3 5.9e-64
XP_011516625 (OMIM: 610691) PREDICTED: protein pru (3089) 1142 245.5 1.1e-63
XP_006717049 (OMIM: 610691) PREDICTED: protein pru (3100) 1141 245.3 1.2e-63
XP_016869841 (OMIM: 610691) PREDICTED: protein pru (3071) 1140 245.1 1.4e-63
XP_016869835 (OMIM: 610691) PREDICTED: protein pru (3087) 1140 245.1 1.4e-63
XP_006717048 (OMIM: 610691) PREDICTED: protein pru (3101) 1137 244.4 2.2e-63
XP_005251811 (OMIM: 610691) PREDICTED: protein pru (3060) 1136 244.2 2.5e-63
XP_016869840 (OMIM: 610691) PREDICTED: protein pru (3072) 1136 244.2 2.5e-63
XP_005251807 (OMIM: 610691) PREDICTED: protein pru (3088) 1136 244.2 2.5e-63
XP_016869846 (OMIM: 610691) PREDICTED: protein pru ( 340) 1120 240.4 4e-63
XP_016869834 (OMIM: 610691) PREDICTED: protein pru (3091) 1130 243.0 5.8e-63
XP_005251802 (OMIM: 610691) PREDICTED: protein pru (3092) 1126 242.2 1e-62
XP_006717046 (OMIM: 610691) PREDICTED: protein pru (3103) 1125 242.0 1.2e-62
NP_001294976 (OMIM: 610691) protein prune homolog (3062) 1124 241.8 1.4e-62
XP_016869839 (OMIM: 610691) PREDICTED: protein pru (3074) 1124 241.8 1.4e-62
XP_016869838 (OMIM: 610691) PREDICTED: protein pru (3075) 1124 241.8 1.4e-62
XP_005251805 (OMIM: 610691) PREDICTED: protein pru (3090) 1124 241.8 1.4e-62
XP_011516628 (OMIM: 610691) PREDICTED: protein pru (3085) 1121 241.2 2.1e-62
XP_006717047 (OMIM: 610691) PREDICTED: protein pru (3101) 1121 241.2 2.1e-62
XP_006717045 (OMIM: 610691) PREDICTED: protein pru (3104) 1121 241.2 2.1e-62
NP_001294977 (OMIM: 610691) protein prune homolog (3063) 1120 240.9 2.4e-62
XP_011516630 (OMIM: 610691) PREDICTED: protein pru (3072) 1120 240.9 2.4e-62
XP_005251808 (OMIM: 610691) PREDICTED: protein pru (3075) 1120 240.9 2.4e-62
XP_016869837 (OMIM: 610691) PREDICTED: protein pru (3076) 1120 240.9 2.4e-62
XP_005251803 (OMIM: 610691) PREDICTED: protein pru (3091) 1120 240.9 2.4e-62
XP_016869836 (OMIM: 610691) PREDICTED: protein pru (3078) 1108 238.5 1.3e-61
XP_016869842 (OMIM: 610691) PREDICTED: protein pru (3068) 1104 237.6 2.4e-61
XP_011516629 (OMIM: 610691) PREDICTED: protein pru (3079) 1104 237.6 2.4e-61
NP_149053 (OMIM: 601238,608179) caytaxin [Homo sap ( 371) 971 209.7 7.5e-54
NP_612122 (OMIM: 611275) bcl-2/adenovirus E1B 19 k ( 357) 914 197.9 2.5e-50
NP_001153114 (OMIM: 611275) bcl-2/adenovirus E1B 1 ( 275) 908 196.6 4.8e-50
XP_016855909 (OMIM: 611275) PREDICTED: bcl-2/adeno ( 191) 823 179.0 6.6e-45
XP_011507538 (OMIM: 611275) PREDICTED: bcl-2/adeno ( 343) 704 154.7 2.5e-37
XP_011518397 (OMIM: 602732) PREDICTED: rho GTPase- ( 439) 400 92.1 2.2e-18
NP_004299 (OMIM: 602732) rho GTPase-activating pro ( 439) 400 92.1 2.2e-18
NP_001185655 (OMIM: 609405) rho GTPase-activating ( 305) 345 80.7 4.2e-15
NP_851852 (OMIM: 609405) rho GTPase-activating pro ( 433) 345 80.8 5.6e-15
XP_016873209 (OMIM: 602732) PREDICTED: rho GTPase- ( 395) 226 56.2 1.3e-07
NP_001017526 (OMIM: 609405) rho GTPase-activating ( 464) 183 47.4 6.6e-05
>>NP_001307604 (OMIM: 603292) BCL2/adenovirus E1B 19 kDa (376 aa)
initn: 2105 init1: 2105 opt: 2105 Z-score: 2350.2 bits: 443.3 E(85289): 3.6e-124
Smith-Waterman score: 2105; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:63-376)
10 20 30
pF1KB6 MEGVELKEEWQDEDFPIPLPEDDSIEADIL
::::::::::::::::::::::::::::::
NP_001 SWYRTKKLGLLDIGSLDYQEFVVDIESRLRMEGVELKEEWQDEDFPIPLPEDDSIEADIL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB6 AITGPEDQPGSLEVNGNKVRKKLMAPDISLTLDPSDGSVLSDDLDESGEIDLDGLDTPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AITGPEDQPGSLEVNGNKVRKKLMAPDISLTLDPSDGSVLSDDLDESGEIDLDGLDTPSE
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB6 NSNEFEWEDDLPKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSNEFEWEDDLPKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPY
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB6 KKVISHGGYYGDGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKVISHGGYYGDGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVY
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB6 LNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQ
280 290 300 310 320 330
280 290 300 310
pF1KB6 KIRYVFNLAELAELVPMEYVGIPECIKQVDQELNGKQDEPKNEQ
::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIRYVFNLAELAELVPMEYVGIPECIKQVDQELNGKQDEPKNEQ
340 350 360 370
>>NP_004321 (OMIM: 603292) BCL2/adenovirus E1B 19 kDa pr (435 aa)
initn: 2105 init1: 2105 opt: 2105 Z-score: 2349.2 bits: 443.3 E(85289): 4.1e-124
Smith-Waterman score: 2105; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:122-435)
10 20 30
pF1KB6 MEGVELKEEWQDEDFPIPLPEDDSIEADIL
::::::::::::::::::::::::::::::
NP_004 EEDEGAKASSGDIGSLDYQEFVVDIESRLRMEGVELKEEWQDEDFPIPLPEDDSIEADIL
100 110 120 130 140 150
40 50 60 70 80 90
pF1KB6 AITGPEDQPGSLEVNGNKVRKKLMAPDISLTLDPSDGSVLSDDLDESGEIDLDGLDTPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AITGPEDQPGSLEVNGNKVRKKLMAPDISLTLDPSDGSVLSDDLDESGEIDLDGLDTPSE
160 170 180 190 200 210
100 110 120 130 140 150
pF1KB6 NSNEFEWEDDLPKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NSNEFEWEDDLPKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPY
220 230 240 250 260 270
160 170 180 190 200 210
pF1KB6 KKVISHGGYYGDGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KKVISHGGYYGDGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVY
280 290 300 310 320 330
220 230 240 250 260 270
pF1KB6 LNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQ
340 350 360 370 380 390
280 290 300 310
pF1KB6 KIRYVFNLAELAELVPMEYVGIPECIKQVDQELNGKQDEPKNEQ
::::::::::::::::::::::::::::::::::::::::::::
NP_004 KIRYVFNLAELAELVPMEYVGIPECIKQVDQELNGKQDEPKNEQ
400 410 420 430
>>NP_001307603 (OMIM: 603292) BCL2/adenovirus E1B 19 kDa (447 aa)
initn: 2005 init1: 2005 opt: 2006 Z-score: 2238.9 bits: 422.9 E(85289): 5.8e-118
Smith-Waterman score: 2071; 96.3% identity (96.3% similar) in 326 aa overlap (1-314:122-447)
10 20 30
pF1KB6 MEGVELKEEWQDEDFPIPLPEDDSIEADIL
::::::::::::::::::::::::::::::
NP_001 EEDEGAKASSGDIGSLDYQEFVVDIESRLRMEGVELKEEWQDEDFPIPLPEDDSIEADIL
100 110 120 130 140 150
40 50 60 70 80 90
pF1KB6 AITGPEDQPGSLEVNGNKVRKKLMAPDISLTLDPSDGSVLSDDLDESGEIDLDGLDTPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AITGPEDQPGSLEVNGNKVRKKLMAPDISLTLDPSDGSVLSDDLDESGEIDLDGLDTPSE
160 170 180 190 200 210
100 110 120 130 140 150
pF1KB6 NSNEFEWEDDLPKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSNEFEWEDDLPKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPY
220 230 240 250 260 270
160 170 180 190 200 210
pF1KB6 KKVISHGGYYGDGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKVISHGGYYGDGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVY
280 290 300 310 320 330
220 230 240 250 260 270
pF1KB6 LNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQ
340 350 360 370 380 390
280 290 300 310
pF1KB6 KIRYVFNLAELAELVPMEYVGIPECIKQ------------VDQELNGKQDEPKNEQ
:::::::::::::::::::::::::::: ::::::::::::::::
NP_001 KIRYVFNLAELAELVPMEYVGIPECIKQYEEEKFKKKQKRVDQELNGKQDEPKNEQ
400 410 420 430 440
>>XP_016869847 (OMIM: 610691) PREDICTED: protein prune h (337 aa)
initn: 1074 init1: 968 opt: 1150 Z-score: 1287.7 bits: 246.5 E(85289): 5.5e-65
Smith-Waterman score: 1150; 57.5% identity (80.0% similar) in 315 aa overlap (1-311:1-312)
10 20 30 40 50
pF1KB6 MEGVELKEEWQDEDFPIPLPEDDSIEADILAITGPEDQPGSLEVNGNKVRK-KLMAPDIS
:.:.. :. .:: . .: .... . : :: :.::..: .. :. :: ::.:.
XP_016 MNGLRNKQ-LLSEDVGMDIPFEEGVLSPSAADMRPEP-PNSLDLNDTHPRRIKLTAPNIN
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 LTLDPSDGSVLSDD-LDESGEIDL--DGLDTPSENSNEFEWEDDLPKPKTTEVIRKGSIT
:.:: :.::.:::: :: :::. : ::::.: .. ::. : . .. ::
XP_016 LSLDQSEGSILSDDNLDSPDEIDINVDELDTPDE-ADSFEYTGHDPTANKDSGQESESIP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 EYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYGDGLNAIVVFAVCFMP
:::: ::.::.: :: ::::..:.:::.::::..:::::::::::::::.:::.::.:
XP_016 EYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 ESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKCYQQIDRR
.::. .:.:.:.::: :::.::::.:::.:::::::::: ::.::.:::..::::.::::
XP_016 DSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 LRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECI
:::::::.:::::::::::.:::::::::::::.::.:: .:.::. :.::. . ::: :
XP_016 LRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESI
240 250 260 270 280 290
300 310
pF1KB6 KQVDQELNGKQDEPKNEQ
..:.:: .. :
XP_016 IKLDEELREASEAAKTSCLYNDPEMSSMEKDIDLKLKEKP
300 310 320 330
>>NP_001294978 (OMIM: 610691) protein prune homolog 2 is (337 aa)
initn: 1074 init1: 968 opt: 1150 Z-score: 1287.7 bits: 246.5 E(85289): 5.5e-65
Smith-Waterman score: 1150; 57.5% identity (80.0% similar) in 315 aa overlap (1-311:1-312)
10 20 30 40 50
pF1KB6 MEGVELKEEWQDEDFPIPLPEDDSIEADILAITGPEDQPGSLEVNGNKVRK-KLMAPDIS
:.:.. :. .:: . .: .... . : :: :.::..: .. :. :: ::.:.
NP_001 MNGLRNKQ-LLSEDVGMDIPFEEGVLSPSAADMRPEP-PNSLDLNDTHPRRIKLTAPNIN
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 LTLDPSDGSVLSDD-LDESGEIDL--DGLDTPSENSNEFEWEDDLPKPKTTEVIRKGSIT
:.:: :.::.:::: :: :::. : ::::.: .. ::. : . .. ::
NP_001 LSLDQSEGSILSDDNLDSPDEIDINVDELDTPDE-ADSFEYTGHDPTANKDSGQESESIP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 EYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYGDGLNAIVVFAVCFMP
:::: ::.::.: :: ::::..:.:::.::::..:::::::::::::::.:::.::.:
NP_001 EYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 ESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKCYQQIDRR
.::. .:.:.:.::: :::.::::.:::.:::::::::: ::.::.:::..::::.::::
NP_001 DSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 LRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECI
:::::::.:::::::::::.:::::::::::::.::.:: .:.::. :.::. . ::: :
NP_001 LRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESI
240 250 260 270 280 290
300 310
pF1KB6 KQVDQELNGKQDEPKNEQ
..:.:: .. :
NP_001 IKLDEELREASEAAKTSCLYNDPEMSSMEKDIDLKLKEKP
300 310 320 330
>>NP_001294979 (OMIM: 610691) protein prune homolog 2 is (352 aa)
initn: 1074 init1: 968 opt: 1146 Z-score: 1282.9 bits: 245.7 E(85289): 1e-64
Smith-Waterman score: 1146; 58.7% identity (80.5% similar) in 303 aa overlap (13-311:27-327)
10 20 30 40
pF1KB6 MEGVELKEEWQDEDFPIPLPEDDSIEADILAITGPEDQPGSLEVNG
:: . .: .... . : :: :.::..:
NP_001 MLKSCSRASFSPSVRKPPLILRRLLSEDVGMDIPFEEGVLSPSAADMRPEP-PNSLDLND
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 NKVRK-KLMAPDISLTLDPSDGSVLSDD-LDESGEIDL--DGLDTPSENSNEFEWEDDLP
.. :. :: ::.:.:.:: :.::.:::: :: :::. : ::::.: .. ::. :
NP_001 THPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDE-ADSFEYTGHDP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 KPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYGD
. .. :: :::: ::.::.: :: ::::..:.:::.::::..::::::::::
NP_001 TANKDSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGD
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 GLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPS
:::::.:::.::.:.::. .:.:.:.::: :::.::::.:::.:::::::::: ::.::.
NP_001 GLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 LGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELA
:::..::::.:::::::::::.:::::::::::.:::::::::::::.::.:: .:.::.
NP_001 LGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELS
240 250 260 270 280 290
290 300 310
pF1KB6 ELVPMEYVGIPECIKQVDQELNGKQDEPKNEQ
:.::. . ::: : ..:.:: .. :
NP_001 GLIPMDCIHIPESIIKLDEELREASEAAKTSCLYNDPEMSSMEKDIDLKLKEKP
300 310 320 330 340 350
>>NP_001317609 (OMIM: 610691) protein prune homolog 2 is (353 aa)
initn: 1093 init1: 987 opt: 1142 Z-score: 1278.5 bits: 244.9 E(85289): 1.8e-64
Smith-Waterman score: 1142; 58.9% identity (80.9% similar) in 304 aa overlap (13-311:27-328)
10 20 30 40
pF1KB6 MEGVELKEEWQDEDFPIPLPEDDSIEADILAITGPEDQPGSLEVNG
:: . .: .... . : :: :.::..:
NP_001 MLKSCSRASFSPSVRKPPLILRRLLSEDVGMDIPFEEGVLSPSAADMRPEP-PNSLDLND
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 NKVRK-KLMAPDISLTLDPSDGSVLSDD-LDESGEIDL--DGLDTPSE-NSNEFEWEDDL
.. :. :: ::.:.:.:: :.::.:::: :: :::. : ::::.: .: :. ..:
NP_001 THPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHED-
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 PKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYG
: . .. :: :::: ::.::.: :: ::::..:.:::.::::..:::::::::
NP_001 PTANKDSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 DGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMP
::::::.:::.::.:.::. .:.:.:.::: :::.::::.:::.:::::::::: ::.::
NP_001 DGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 SLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAEL
.:::..::::.:::::::::::.:::::::::::.:::::::::::::.::.:: .:.::
NP_001 GLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSEL
240 250 260 270 280 290
290 300 310
pF1KB6 AELVPMEYVGIPECIKQVDQELNGKQDEPKNEQ
. :.::. . ::: : ..:.:: .. :
NP_001 SGLIPMDCIHIPESIIKLDEELREASEAAKTSCLYNDPEMSSMEKDIDLKLKEKP
300 310 320 330 340 350
>>XP_016869843 (OMIM: 610691) PREDICTED: protein prune h (365 aa)
initn: 1071 init1: 965 opt: 1137 Z-score: 1272.7 bits: 243.9 E(85289): 3.8e-64
Smith-Waterman score: 1137; 58.3% identity (80.8% similar) in 307 aa overlap (13-314:27-331)
10 20 30 40
pF1KB6 MEGVELKEEWQDEDFPIPLPEDDSIEADILAITGPEDQPGSLEVNG
:: . .: .... . : :: :.::..:
XP_016 MLKSCSRASFSPSVRKPPLILRRLLSEDVGMDIPFEEGVLSPSAADMRPEP-PNSLDLND
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 NKVRK-KLMAPDISLTLDPSDGSVLSDD-LDESGEIDL--DGLDTPSE-NSNEFEWEDDL
.. :. :: ::.:.:.:: :.::.:::: :: :::. : ::::.: .: :. ..:
XP_016 THPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHED-
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 PKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYG
: . .. :: :::: ::.::.: :: ::::..:.:::.::::..:::::::::
XP_016 PTANKDSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 DGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMP
::::::.:::.::.:.::. .:.:.:.::: :::.::::.:::.:::::::::: ::.::
XP_016 DGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 SLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAEL
.:::..::::.:::::::::::.:::::::::::.:::::::::::::.::.:: .:.::
XP_016 GLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSEL
240 250 260 270 280 290
290 300 310
pF1KB6 AELVPMEYVGIPECIKQVDQELNGKQDEPKNEQ
. :.::. . ::: : . :.: . :.. .:.
XP_016 SGLIPMDCIHIPESIIKYDEERSYKRSVRLDEELREASEAAKTSCLYNDPEMSSMEKDID
300 310 320 330 340 350
XP_016 LKLKEKP
360
>>NP_001294980 (OMIM: 610691) protein prune homolog 2 is (324 aa)
initn: 1092 init1: 967 opt: 1136 Z-score: 1272.3 bits: 243.6 E(85289): 4e-64
Smith-Waterman score: 1136; 59.5% identity (81.6% similar) in 299 aa overlap (13-306:27-323)
10 20 30 40
pF1KB6 MEGVELKEEWQDEDFPIPLPEDDSIEADILAITGPEDQPGSLEVNG
:: . .: .... . : :: :.::..:
NP_001 MLKSCSRASFSPSVRKPPLILRRLLSEDVGMDIPFEEGVLSPSAADMRPEP-PNSLDLND
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 NKVRK-KLMAPDISLTLDPSDGSVLSDD-LDESGEIDL--DGLDTPSE-NSNEFEWEDDL
.. :. :: ::.:.:.:: :.::.:::: :: :::. : ::::.: .: :. ..:
NP_001 THPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHED-
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 PKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYG
: . .. :: :::: ::.::.: :: ::::..:.:::.::::..:::::::::
NP_001 PTANKDSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 DGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMP
::::::.:::.::.:.::. .:.:.:.::: :::.::::.:::.:::::::::: ::.::
NP_001 DGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 SLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAEL
.:::..::::.:::::::::::.:::::::::::.:::::::::::::.::.:: .:.::
NP_001 GLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSEL
240 250 260 270 280 290
290 300 310
pF1KB6 AELVPMEYVGIPECIKQVDQELNGKQDEPKNEQ
. :.::. . ::: : ..: .:. :
NP_001 SGLIPMDCIHIPESIINIDLKLKEKP
300 310 320
>>XP_016869848 (OMIM: 610691) PREDICTED: protein prune h (336 aa)
initn: 1090 init1: 965 opt: 1136 Z-score: 1272.1 bits: 243.6 E(85289): 4.1e-64
Smith-Waterman score: 1136; 59.3% identity (81.3% similar) in 300 aa overlap (13-307:27-324)
10 20 30 40
pF1KB6 MEGVELKEEWQDEDFPIPLPEDDSIEADILAITGPEDQPGSLEVNG
:: . .: .... . : :: :.::..:
XP_016 MLKSCSRASFSPSVRKPPLILRRLLSEDVGMDIPFEEGVLSPSAADMRPEP-PNSLDLND
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 NKVRK-KLMAPDISLTLDPSDGSVLSDD-LDESGEIDL--DGLDTPSE-NSNEFEWEDDL
.. :. :: ::.:.:.:: :.::.:::: :: :::. : ::::.: .: :. ..:
XP_016 THPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHED-
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 PKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYG
: . .. :: :::: ::.::.: :: ::::..:.:::.::::..:::::::::
XP_016 PTANKDSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 DGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMP
::::::.:::.::.:.::. .:.:.:.::: :::.::::.:::.:::::::::: ::.::
XP_016 DGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 SLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAEL
.:::..::::.:::::::::::.:::::::::::.:::::::::::::.::.:: .:.::
XP_016 GLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSEL
240 250 260 270 280 290
290 300 310
pF1KB6 AELVPMEYVGIPECIKQVDQELNGKQDEPKNEQ
. :.::. . ::: : . :.: . :.
XP_016 SGLIPMDCIHIPESIIKYDEERSYKRSVSIDLKLKEKP
300 310 320 330
314 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:45:06 2016 done: Sat Nov 5 18:45:07 2016
Total Scan time: 6.720 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]