Result of FASTA (omim) for pF1KB6448
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6448, 349 aa
  1>>>pF1KB6448 349 - 349 aa - 349 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2238+/-0.000361; mu= 17.3705+/- 0.022
 mean_var=68.5666+/-13.940, 0's: 0 Z-trim(114.3): 80  B-trim: 166 in 1/55
 Lambda= 0.154888
 statistics sampled from 24050 (24131) to 24050 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.283), width:  16
 Scan time:  6.900

The best scores are:                                      opt bits E(85289)
NP_060372 (OMIM: 606615) hypoxia-inducible factor  ( 349) 2427 551.2 1.3e-156
XP_011538242 (OMIM: 606615) PREDICTED: hypoxia-ind ( 369) 2048 466.5 4.1e-131
XP_011538243 (OMIM: 606615) PREDICTED: hypoxia-ind ( 242) 1721 393.3 2.9e-109
NP_078886 (OMIM: 608263) HSPB1-associated protein  ( 488)  325 81.5 4.1e-15
XP_011511432 (OMIM: 608263) PREDICTED: HSPB1-assoc ( 451)  316 79.5 1.6e-14
XP_016879169 (OMIM: 611917) PREDICTED: lysine-spec ( 164)  302 76.1   6e-14
XP_016879166 (OMIM: 611917) PREDICTED: lysine-spec ( 199)  302 76.2   7e-14
XP_016879167 (OMIM: 611917) PREDICTED: lysine-spec ( 199)  302 76.2   7e-14
XP_016879168 (OMIM: 611917) PREDICTED: lysine-spec ( 199)  302 76.2   7e-14
NP_079049 (OMIM: 611917) lysine-specific demethyla ( 416)  302 76.4 1.3e-13
NP_001138820 (OMIM: 611917) lysine-specific demeth ( 454)  302 76.4 1.4e-13
XP_016862668 (OMIM: 608263) PREDICTED: HSPB1-assoc ( 426)  283 72.1 2.5e-12
XP_011511434 (OMIM: 608263) PREDICTED: HSPB1-assoc ( 449)  283 72.1 2.6e-12
XP_005247819 (OMIM: 608263) PREDICTED: HSPB1-assoc ( 280)  226 59.3 1.2e-08
NP_001307657 (OMIM: 608263) HSPB1-associated prote ( 460)  215 57.0 9.8e-08
XP_016879165 (OMIM: 611917) PREDICTED: lysine-spec ( 385)  182 49.5 1.4e-05


>>NP_060372 (OMIM: 606615) hypoxia-inducible factor 1-al  (349 aa)
 initn: 2427 init1: 2427 opt: 2427  Z-score: 2932.9  bits: 551.2 E(85289): 1.3e-156
Smith-Waterman score: 2427; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349)

               10        20        30        40        50        60
pF1KB6 MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 PVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 EEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 QLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGA
              250       260       270       280       290       300

              310       320       330       340         
pF1KB6 PTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN
              310       320       330       340         

>>XP_011538242 (OMIM: 606615) PREDICTED: hypoxia-inducib  (369 aa)
 initn: 2048 init1: 2048 opt: 2048  Z-score: 2474.9  bits: 466.5 E(85289): 4.1e-131
Smith-Waterman score: 2377; 94.6% identity (94.6% similar) in 369 aa overlap (1-349:1-369)

               10        20        30        40        50          
pF1KB6 MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENE-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEV
               10        20        30        40        50        60

                         60        70        80        90       100
pF1KB6 -------------------EPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKF
                          :::::::::::::::::::::::::::::::::::::::::
XP_011 GGGAASKGRGGRYPVERSEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKF
               70        80        90       100       110       120

              110       120       130       140       150       160
pF1KB6 LYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVM
              130       140       150       160       170       180

              170       180       190       200       210       220
pF1KB6 DFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFP
              190       200       210       220       230       240

              230       240       250       260       270       280
pF1KB6 PDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHH
              250       260       270       280       290       300

              290       300       310       320       330       340
pF1KB6 IESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLL
              310       320       330       340       350       360

                
pF1KB6 NTMIKGRYN
       :::::::::
XP_011 NTMIKGRYN
                

>>XP_011538243 (OMIM: 606615) PREDICTED: hypoxia-inducib  (242 aa)
 initn: 1721 init1: 1721 opt: 1721  Z-score: 2082.6  bits: 393.3 E(85289): 2.9e-109
Smith-Waterman score: 1721; 100.0% identity (100.0% similar) in 242 aa overlap (108-349:1-242)

        80        90       100       110       120       130       
pF1KB6 LEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQ
                                     ::::::::::::::::::::::::::::::
XP_011                               MANFQNFKPRSNREEMKFHEFVEKLQDIQQ
                                             10        20        30

       140       150       160       170       180       190       
pF1KB6 RGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTP
               40        50        60        70        80        90

       200       210       220       230       240       250       
pF1KB6 AHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQN
              100       110       120       130       140       150

       260       270       280       290       300       310       
pF1KB6 VVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVA
              160       170       180       190       200       210

       320       330       340         
pF1KB6 IMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN
       ::::::::::::::::::::::::::::::::
XP_011 IMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN
              220       230       240  

>>NP_078886 (OMIM: 608263) HSPB1-associated protein 1 is  (488 aa)
 initn: 282 init1: 160 opt: 325  Z-score: 392.3  bits: 81.5 E(85289): 4.1e-15
Smith-Waterman score: 329; 27.0% identity (55.3% similar) in 300 aa overlap (51-341:32-309)

               30        40        50         60        70         
pF1KB6 GALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIEN-EEPVVLTDTNLVYPALKWDLE
                                     .:.:.: . ..:... .  . .:: .:. .
NP_078 AAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNAK
              10        20        30        40        50        60 

      80        90       100       110       120       130         
pF1KB6 YLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRG
       ::..        :  ..  .:  .  :.:..  .:.   :  :  ..::.    : .. .
NP_078 YLSQ--------VLHGKQIRF-RMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSIS
                      70         80        90       100       110  

     140       150       160             170       180       190   
pF1KB6 GEERLYLQQTLNDTVGRKIVMDF------LGFNWNWINKQQGKRGWGQLTSNLLLIGMEG
       :  : : .. .   .  :  ...      :  . .: .     :. :: ..  : ::  :
NP_078 GPFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRN-GQEST--LWIGSLG
            120       130       140       150        160           

           200        210       220       230        240       250 
pF1KB6 NVTPAHYDEQQ-NFFAQIKGYKRCILFPPDQFECLYPYPV-HHPCDRQSQVDFDNPDYER
         :: : :    :.  :..: ::  ::::..   :::  . ..  .  :...  ::: .:
NP_078 AHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKR
     170       180       190       200       210       220         

             260       270       280       290       300       310 
pF1KB6 FPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLK
       ::.:...  . ....::.::..: .:::..::.    .:...: : .       .:    
NP_078 FPQFRKAQRHAVTLSPGQVLFVPRHWWHYVESI--DPVTVSINSWIE-------LEEDHL
     230       240       250       260         270              280

             320       330       340                               
pF1KB6 AHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN                      
       :. . :: : .   :  :  :::..   ::                              
NP_078 ARVEEAITRMLVCALKTAE-NPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTS
              290        300       310       320       330         

>>XP_011511432 (OMIM: 608263) PREDICTED: HSPB1-associate  (451 aa)
 initn: 311 init1: 160 opt: 316  Z-score: 381.9  bits: 79.5 E(85289): 1.6e-14
Smith-Waterman score: 320; 26.8% identity (54.6% similar) in 291 aa overlap (59-341:4-272)

       30        40        50        60        70        80        
pF1KB6 ESQLRSYSFPTRPIPRLSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNG
                                     ..:... .  . .:: .:. .::..     
XP_011                            MSLQQPAIFCNMVFDWPARHWNAKYLSQ-----
                                          10        20             

       90       100       110       120       130       140        
pF1KB6 DFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQ
          :  ..  .:  .  :.:..  .:.   :  :  ..::.    : .. .:  : : ..
XP_011 ---VLHGKQIRF-RMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDHS
          30         40        50        60        70        80    

      150       160             170       180       190       200  
pF1KB6 TLNDTVGRKIVMDF------LGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDE
        .   .  :  ...      :  . .: .     :. :: ..  : ::  :  :: : : 
XP_011 KFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRN-GQEST--LWIGSLGAHTPCHLDS
           90       100       110       120          130       140 

             210       220       230        240       250       260
pF1KB6 QQ-NFFAQIKGYKRCILFPPDQFECLYPYPV-HHPCDRQSQVDFDNPDYERFPNFQNVVG
          :.  :..: ::  ::::..   :::  . ..  .  :...  ::: .:::.:...  
XP_011 YGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQR
             150       160       170       180       190       200 

              270       280       290       300       310       320
pF1KB6 YETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMR
       . ....::.::..: .:::..::.    .:...: : .       .:    :. . :: :
XP_011 HAVTLSPGQVLFVPRHWWHYVESI--DPVTVSINSWIE-------LEEDHLARVEEAITR
             210       220         230              240       250  

              330       340                                        
pF1KB6 NIEKMLGEALGNPQEVGPLLNTMIKGRYN                               
        .   :  :  :::..   ::                                       
XP_011 MLVCALKTAE-NPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALR
            260        270       280       290       300       310 

>>XP_016879169 (OMIM: 611917) PREDICTED: lysine-specific  (164 aa)
 initn: 288 init1: 165 opt: 302  Z-score: 371.4  bits: 76.1 E(85289): 6e-14
Smith-Waterman score: 302; 37.0% identity (69.4% similar) in 108 aa overlap (190-297:60-163)

     160       170       180       190       200       210         
pF1KB6 MDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILF
                                     : .:...: : : ::::..:. : :   :.
XP_016 IPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLY
      30        40        50        60        70        80         

     220       230       240       250       260       270         
pF1KB6 PPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWH
        :..   :::. .:      :::: .::: :.::.: ..     ...::..:.::. .::
XP_016 SPQESGALYPHDTHL-LHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWH
      90       100        110       120       130       140        

     280       290       300       310       320       330         
pF1KB6 HIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPL
       ....:    ....:.::.                                          
XP_016 YVRAL---DLSFSVSFWWS                                         
      150          160                                             

>>XP_016879166 (OMIM: 611917) PREDICTED: lysine-specific  (199 aa)
 initn: 333 init1: 165 opt: 302  Z-score: 370.2  bits: 76.2 E(85289): 7e-14
Smith-Waterman score: 309; 29.5% identity (56.2% similar) in 224 aa overlap (75-297:3-198)

           50        60        70        80        90       100    
pF1KB6 LSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYD
                                     ::.:::.::  :     :  .:     : :
XP_016                             MQKWSLEYIQEIAGCRTVPVEVGSR----YTD
                                           10        20            

          110       120       130       140        150       160   
pF1KB6 EKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYL-QQTLNDTVGRKIVMDFL
       :.   ..           :  .::. :    . :   .  :: :. : : .  .. .:. 
XP_016 EEWSQTL-----------MTVNEFISKYIVNEPR---DVGYLAQHQLFDQIP-ELKQDIS
       30                   40        50           60         70   

           170       180       190       200       210       220   
pF1KB6 GFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQ
         ..  ..  . .    ..: :  . : .:...: : : ::::..:. : :   :. :..
XP_016 IPDYCSLGDGEEE----EITINAWF-GPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQE
            80            90        100       110       120        

           230       240       250       260       270       280   
pF1KB6 FECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIES
          :::. .:      :::: .::: :.::.: ..     ...::..:.::. .::....
XP_016 SGALYPHDTHL-LHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRA
      130        140       150       160       170       180       

           290       300       310       320       330       340   
pF1KB6 LLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTM
       :    ....:.::.                                              
XP_016 L---DLSFSVSFWWS                                             
          190                                                      

>>XP_016879167 (OMIM: 611917) PREDICTED: lysine-specific  (199 aa)
 initn: 333 init1: 165 opt: 302  Z-score: 370.2  bits: 76.2 E(85289): 7e-14
Smith-Waterman score: 309; 29.5% identity (56.2% similar) in 224 aa overlap (75-297:3-198)

           50        60        70        80        90       100    
pF1KB6 LSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYD
                                     ::.:::.::  :     :  .:     : :
XP_016                             MQKWSLEYIQEIAGCRTVPVEVGSR----YTD
                                           10        20            

          110       120       130       140        150       160   
pF1KB6 EKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYL-QQTLNDTVGRKIVMDFL
       :.   ..           :  .::. :    . :   .  :: :. : : .  .. .:. 
XP_016 EEWSQTL-----------MTVNEFISKYIVNEPR---DVGYLAQHQLFDQIP-ELKQDIS
       30                   40        50           60         70   

           170       180       190       200       210       220   
pF1KB6 GFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQ
         ..  ..  . .    ..: :  . : .:...: : : ::::..:. : :   :. :..
XP_016 IPDYCSLGDGEEE----EITINAWF-GPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQE
            80            90        100       110       120        

           230       240       250       260       270       280   
pF1KB6 FECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIES
          :::. .:      :::: .::: :.::.: ..     ...::..:.::. .::....
XP_016 SGALYPHDTHL-LHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRA
      130        140       150       160       170       180       

           290       300       310       320       330       340   
pF1KB6 LLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTM
       :    ....:.::.                                              
XP_016 L---DLSFSVSFWWS                                             
          190                                                      

>>XP_016879168 (OMIM: 611917) PREDICTED: lysine-specific  (199 aa)
 initn: 333 init1: 165 opt: 302  Z-score: 370.2  bits: 76.2 E(85289): 7e-14
Smith-Waterman score: 309; 29.5% identity (56.2% similar) in 224 aa overlap (75-297:3-198)

           50        60        70        80        90       100    
pF1KB6 LSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYD
                                     ::.:::.::  :     :  .:     : :
XP_016                             MQKWSLEYIQEIAGCRTVPVEVGSR----YTD
                                           10        20            

          110       120       130       140        150       160   
pF1KB6 EKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYL-QQTLNDTVGRKIVMDFL
       :.   ..           :  .::. :    . :   .  :: :. : : .  .. .:. 
XP_016 EEWSQTL-----------MTVNEFISKYIVNEPR---DVGYLAQHQLFDQIP-ELKQDIS
       30                   40        50           60         70   

           170       180       190       200       210       220   
pF1KB6 GFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQ
         ..  ..  . .    ..: :  . : .:...: : : ::::..:. : :   :. :..
XP_016 IPDYCSLGDGEEE----EITINAWF-GPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQE
            80            90        100       110       120        

           230       240       250       260       270       280   
pF1KB6 FECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIES
          :::. .:      :::: .::: :.::.: ..     ...::..:.::. .::....
XP_016 SGALYPHDTHL-LHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRA
      130        140       150       160       170       180       

           290       300       310       320       330       340   
pF1KB6 LLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTM
       :    ....:.::.                                              
XP_016 L---DLSFSVSFWWS                                             
          190                                                      

>>NP_079049 (OMIM: 611917) lysine-specific demethylase 8  (416 aa)
 initn: 333 init1: 165 opt: 302  Z-score: 365.5  bits: 76.4 E(85289): 1.3e-13
Smith-Waterman score: 335; 28.2% identity (56.1% similar) in 262 aa overlap (40-297:182-415)

      10        20        30        40        50          60       
pF1KB6 ASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRA--EELIENEEPVVLTDT
                                     . .::: . . .   :...   .::.:  .
NP_079 KRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPSLQHFREQFLVPGRPVILKGV
             160       170       180       190       200       210 

        70         80        90       100       110       120      
pF1KB6 NLVYPAL-KWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFH
          .: . ::.:::.::  :     :  .:     : ::.            ..  :  .
NP_079 ADHWPCMQKWSLEYIQEIAGCRTVPVEVGSR----YTDEEW-----------SQTLMTVN
             220       230       240                      250      

        130       140        150       160       170       180     
pF1KB6 EFVEKLQDIQQRGGEERLYL-QQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSN
       ::. :    . :   .  :: :. : : .  .. .:.   ..  ..  . .    ..: :
NP_079 EFISKYIVNEPR---DVGYLAQHQLFDQIP-ELKQDISIPDYCSLGDGEEE----EITIN
        260          270       280        290       300            

         190       200       210       220       230       240     
pF1KB6 LLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFD
         . : .:...: : : ::::..:. : :   :. :..   :::. .:      :::: .
NP_079 AWF-GPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHL-LHNTSQVDVE
      310        320       330       340       350        360      

         250       260       270       280       290       300     
pF1KB6 NPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKR
       ::: :.::.: ..     ...::..:.::. .::....:    ....:.::.        
NP_079 NPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRAL---DLSFSVSFWWS       
        370       380       390       400          410             

         310       320       330       340         
pF1KB6 IEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN




349 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 17:32:57 2016 done: Fri Nov  4 17:32:58 2016
 Total Scan time:  6.900 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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