FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6449, 317 aa 1>>>pF1KB6449 317 - 317 aa - 317 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5655+/-0.00042; mu= 10.4510+/- 0.026 mean_var=177.2545+/-36.773, 0's: 0 Z-trim(116.9): 510 B-trim: 83 in 1/50 Lambda= 0.096333 statistics sampled from 27726 (28360) to 27726 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.333), width: 16 Scan time: 7.040 The best scores are: opt bits E(85289) NP_065390 (OMIM: 164008,612132) NF-kappa-B inhibit ( 317) 2141 309.9 4.4e-84 NP_004547 (OMIM: 604548) NF-kappa-B inhibitor epsi ( 500) 483 79.7 1.4e-14 XP_011530310 (OMIM: 164011,616576) PREDICTED: nucl ( 916) 458 76.5 2.2e-13 NP_001158884 (OMIM: 164011,616576) nuclear factor ( 968) 458 76.6 2.3e-13 NP_001306155 (OMIM: 164011,616576) nuclear factor ( 968) 458 76.6 2.3e-13 NP_003989 (OMIM: 164011,616576) nuclear factor NF- ( 969) 458 76.6 2.3e-13 XP_011530308 (OMIM: 164011,616576) PREDICTED: nucl ( 976) 458 76.6 2.3e-13 XP_011538132 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 396 67.8 7.8e-11 XP_011538133 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 396 67.8 7.8e-11 NP_001309864 (OMIM: 164012,615577) nuclear factor ( 858) 396 67.9 8.5e-11 NP_002493 (OMIM: 164012,615577) nuclear factor NF- ( 899) 396 67.9 8.7e-11 NP_001248332 (OMIM: 164012,615577) nuclear factor ( 899) 396 67.9 8.7e-11 NP_001275653 (OMIM: 164012,615577) nuclear factor ( 899) 396 67.9 8.7e-11 NP_001070962 (OMIM: 164012,615577) nuclear factor ( 900) 396 67.9 8.7e-11 NP_001309863 (OMIM: 164012,615577) nuclear factor ( 900) 396 67.9 8.7e-11 XP_016871767 (OMIM: 164012,615577) PREDICTED: nucl (1081) 396 68.0 9.8e-11 XP_016882599 (OMIM: 109560) PREDICTED: B-cell lymp ( 356) 363 62.8 1.2e-09 XP_011525502 (OMIM: 109560) PREDICTED: B-cell lymp ( 378) 363 62.9 1.2e-09 XP_016882598 (OMIM: 109560) PREDICTED: B-cell lymp ( 434) 363 62.9 1.3e-09 NP_005169 (OMIM: 109560) B-cell lymphoma 3 protein ( 454) 363 63.0 1.4e-09 XP_011525499 (OMIM: 109560) PREDICTED: B-cell lymp ( 539) 363 63.1 1.5e-09 XP_011525500 (OMIM: 109560) PREDICTED: B-cell lymp ( 696) 363 63.2 1.8e-09 XP_016865994 (OMIM: 610583) PREDICTED: ankyrin rep ( 659) 287 52.6 2.6e-06 XP_011533901 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 286 52.5 3e-06 XP_006723290 (OMIM: 604495) PREDICTED: NF-kappa-B ( 351) 280 51.3 3.4e-06 NP_001229743 (OMIM: 610583) ankyrin repeat domain- ( 663) 269 50.1 1.5e-05 XP_011533902 (OMIM: 610583) PREDICTED: ankyrin rep ( 663) 269 50.1 1.5e-05 NP_001230045 (OMIM: 604495) NF-kappa-B inhibitor b ( 270) 263 48.8 1.5e-05 XP_006723289 (OMIM: 604495) PREDICTED: NF-kappa-B ( 324) 263 48.9 1.7e-05 NP_002494 (OMIM: 604495) NF-kappa-B inhibitor beta ( 356) 263 48.9 1.8e-05 XP_011512738 (OMIM: 608994) PREDICTED: ankyrin rep (1100) 269 50.4 2e-05 XP_005249021 (OMIM: 608994) PREDICTED: ankyrin rep (1155) 269 50.4 2.1e-05 XP_006715099 (OMIM: 608994) PREDICTED: ankyrin rep (1156) 269 50.4 2.1e-05 XP_011512735 (OMIM: 608994) PREDICTED: ankyrin rep (1162) 269 50.4 2.1e-05 XP_011512734 (OMIM: 608994) PREDICTED: ankyrin rep (1165) 269 50.4 2.1e-05 XP_011512733 (OMIM: 608994) PREDICTED: ankyrin rep (1166) 269 50.4 2.1e-05 NP_001138994 (OMIM: 606586) ankycorbin isoform b [ ( 951) 266 49.9 2.5e-05 XP_016864824 (OMIM: 606586) PREDICTED: ankycorbin ( 951) 266 49.9 2.5e-05 XP_016865992 (OMIM: 610583) PREDICTED: ankyrin rep ( 661) 262 49.1 2.9e-05 XP_011533899 (OMIM: 610583) PREDICTED: ankyrin rep ( 719) 262 49.2 3.1e-05 NP_065815 (OMIM: 612184) caskin-1 [Homo sapiens] (1431) 266 50.1 3.2e-05 XP_011512327 (OMIM: 606586) PREDICTED: ankycorbin ( 957) 263 49.5 3.3e-05 XP_006714532 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 263 49.5 3.4e-05 XP_011512323 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 263 49.5 3.4e-05 XP_011512324 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 263 49.5 3.4e-05 NP_056392 (OMIM: 606586) ankycorbin isoform a [Hom ( 980) 263 49.5 3.4e-05 XP_011512320 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 263 49.5 3.4e-05 XP_011512322 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 263 49.5 3.4e-05 NP_001138992 (OMIM: 606586) ankycorbin isoform a [ ( 980) 263 49.5 3.4e-05 NP_001138993 (OMIM: 606586) ankycorbin isoform a [ ( 980) 263 49.5 3.4e-05 >>NP_065390 (OMIM: 164008,612132) NF-kappa-B inhibitor a (317 aa) initn: 2141 init1: 2141 opt: 2141 Z-score: 1630.5 bits: 309.9 E(85289): 4.4e-84 Smith-Waterman score: 2141; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317) 10 20 30 40 50 60 pF1KB6 MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQEIRLEPQEVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQEIRLEPQEVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQSCTTPHLHSILKATN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQSCTTPHLHSILKATN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 YNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTE 250 260 270 280 290 300 310 pF1KB6 DELPYDDCVFGGQRLTL ::::::::::::::::: NP_065 DELPYDDCVFGGQRLTL 310 >>NP_004547 (OMIM: 604548) NF-kappa-B inhibitor epsilon (500 aa) initn: 457 init1: 237 opt: 483 Z-score: 382.9 bits: 79.7 E(85289): 1.4e-14 Smith-Waterman score: 483; 37.6% identity (65.6% similar) in 250 aa overlap (70-315:255-496) 40 50 60 70 80 90 pF1KB6 EEYEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKG ..::::...:::.::: :. . . . NP_004 GGPEAEDPAPRLPLPHVGALSPQQLEALTYISEDGDTLVHLAVIHEAPAVLLCCLALLPQ 230 240 250 260 270 280 100 110 120 130 140 150 pF1KB6 DLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS .. :..:::: :: ::::: .:: ..::. : . :.: .:.: ::.::.. :: NP_004 EV--LDIQNNLYQTALHLAVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLAC 290 300 310 320 330 340 160 170 180 190 200 210 pF1KB6 VGVLTQSCTTPHL---HSI-LKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPC . : .. : ::. :. :..: .:::.:... ..:::. :::...:: NP_004 ARCLLEGRPEPGRGTSHSLDLQLQNWQGLACLHIATLQKNQPLMELLLRNGADIDVQEGT 350 360 370 380 390 400 220 230 240 250 260 270 pF1KB6 NGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLE .:.:::::::. :. ::..::. ::.:. .: .: .:. :: :.. : . . NP_004 SGKTALHLAVETQERGLVQFLLQAGAQVDARMLNGCTPLHLAAGRGLMGISSTLCKAGAD 410 420 430 440 450 460 280 290 300 310 pF1KB6 NLQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL .: : . ::: : ...:: . ::.:: ..:. : NP_004 SL--LRNVEDE----TPQDLTEESLVLLPFDDLKISGKLLLCTD 470 480 490 500 >>XP_011530310 (OMIM: 164011,616576) PREDICTED: nuclear (916 aa) initn: 434 init1: 164 opt: 458 Z-score: 361.1 bits: 76.5 E(85289): 2.2e-13 Smith-Waterman score: 458; 40.9% identity (65.1% similar) in 235 aa overlap (72-302:489-715) 50 60 70 80 90 100 pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDL :.::: ::::::: .. :. .... ..: . XP_011 RHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLI 460 470 480 490 500 510 110 120 130 140 150 pF1KB6 A--FLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS . ..:..:.: ::::::::::.: ...: :: :: : : : ::. :::: ..: XP_011 SDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKV 520 530 540 550 560 570 160 170 180 190 200 210 pF1KB6 VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRT ...: . . : : : .: . .::: . . : . :::. :::::::: .::: XP_011 LSILLKHKKAALL---LDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRT 580 590 600 610 620 630 220 230 240 250 260 270 pF1KB6 ALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQ ::::::. .: .:.. :::. : :. .::.: .: ... :: :::. : . XP_011 ALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGAD--- 640 650 660 670 680 690 280 290 300 310 pF1KB6 MLPESEDEES-YDTESEFTEFTEDELPYDDCVFGGQRLTL : :. : :: .. . . ::: XP_011 --PLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMATSWQVFDILNGKPYEPEFTSDDL 700 710 720 730 740 750 >>NP_001158884 (OMIM: 164011,616576) nuclear factor NF-k (968 aa) initn: 434 init1: 164 opt: 458 Z-score: 360.8 bits: 76.6 E(85289): 2.3e-13 Smith-Waterman score: 458; 40.9% identity (65.1% similar) in 235 aa overlap (72-302:541-767) 50 60 70 80 90 100 pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDL :.::: ::::::: .. :. .... ..: . NP_001 RHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLI 520 530 540 550 560 570 110 120 130 140 150 pF1KB6 A--FLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS . ..:..:.: ::::::::::.: ...: :: :: : : : ::. :::: ..: NP_001 SDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKV 580 590 600 610 620 630 160 170 180 190 200 210 pF1KB6 VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRT ...: . . : : : .: . .::: . . : . :::. :::::::: .::: NP_001 LSILLKHKKAALL---LDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRT 640 650 660 670 680 220 230 240 250 260 270 pF1KB6 ALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQ ::::::. .: .:.. :::. : :. .::.: .: ... :: :::. : . NP_001 ALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGAD--- 690 700 710 720 730 740 280 290 300 310 pF1KB6 MLPESEDEES-YDTESEFTEFTEDELPYDDCVFGGQRLTL : :. : :: .. . . ::: NP_001 --PLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMATSWQVFDILNGKPYEPEFTSDDL 750 760 770 780 790 800 >>NP_001306155 (OMIM: 164011,616576) nuclear factor NF-k (968 aa) initn: 434 init1: 164 opt: 458 Z-score: 360.8 bits: 76.6 E(85289): 2.3e-13 Smith-Waterman score: 458; 40.9% identity (65.1% similar) in 235 aa overlap (72-302:541-767) 50 60 70 80 90 100 pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDL :.::: ::::::: .. :. .... ..: . NP_001 RHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLI 520 530 540 550 560 570 110 120 130 140 150 pF1KB6 A--FLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS . ..:..:.: ::::::::::.: ...: :: :: : : : ::. :::: ..: NP_001 SDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKV 580 590 600 610 620 630 160 170 180 190 200 210 pF1KB6 VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRT ...: . . : : : .: . .::: . . : . :::. :::::::: .::: NP_001 LSILLKHKKAALL---LDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRT 640 650 660 670 680 220 230 240 250 260 270 pF1KB6 ALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQ ::::::. .: .:.. :::. : :. .::.: .: ... :: :::. : . NP_001 ALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGAD--- 690 700 710 720 730 740 280 290 300 310 pF1KB6 MLPESEDEES-YDTESEFTEFTEDELPYDDCVFGGQRLTL : :. : :: .. . . ::: NP_001 --PLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMATSWQVFDILNGKPYEPEFTSDDL 750 760 770 780 790 800 >>NP_003989 (OMIM: 164011,616576) nuclear factor NF-kapp (969 aa) initn: 434 init1: 164 opt: 458 Z-score: 360.8 bits: 76.6 E(85289): 2.3e-13 Smith-Waterman score: 458; 40.9% identity (65.1% similar) in 235 aa overlap (72-302:542-768) 50 60 70 80 90 100 pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDL :.::: ::::::: .. :. .... ..: . NP_003 RHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLI 520 530 540 550 560 570 110 120 130 140 150 pF1KB6 A--FLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS . ..:..:.: ::::::::::.: ...: :: :: : : : ::. :::: ..: NP_003 SDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKV 580 590 600 610 620 630 160 170 180 190 200 210 pF1KB6 VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRT ...: . . : : : .: . .::: . . : . :::. :::::::: .::: NP_003 LSILLKHKKAALL---LDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRT 640 650 660 670 680 220 230 240 250 260 270 pF1KB6 ALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQ ::::::. .: .:.. :::. : :. .::.: .: ... :: :::. : . NP_003 ALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGAD--- 690 700 710 720 730 740 280 290 300 310 pF1KB6 MLPESEDEES-YDTESEFTEFTEDELPYDDCVFGGQRLTL : :. : :: .. . . ::: NP_003 --PLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMATSWQVFDILNGKPYEPEFTSDDL 750 760 770 780 790 800 >>XP_011530308 (OMIM: 164011,616576) PREDICTED: nuclear (976 aa) initn: 434 init1: 164 opt: 458 Z-score: 360.8 bits: 76.6 E(85289): 2.3e-13 Smith-Waterman score: 458; 40.9% identity (65.1% similar) in 235 aa overlap (72-302:549-775) 50 60 70 80 90 100 pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDL :.::: ::::::: .. :. .... ..: . XP_011 RHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLI 520 530 540 550 560 570 110 120 130 140 150 pF1KB6 A--FLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS . ..:..:.: ::::::::::.: ...: :: :: : : : ::. :::: ..: XP_011 SDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKV 580 590 600 610 620 630 160 170 180 190 200 210 pF1KB6 VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRT ...: . . : : : .: . .::: . . : . :::. :::::::: .::: XP_011 LSILLKHKKAALL---LDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRT 640 650 660 670 680 690 220 230 240 250 260 270 pF1KB6 ALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQ ::::::. .: .:.. :::. : :. .::.: .: ... :: :::. : . XP_011 ALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGAD--- 700 710 720 730 740 750 280 290 300 310 pF1KB6 MLPESEDEES-YDTESEFTEFTEDELPYDDCVFGGQRLTL : :. : :: .. . . ::: XP_011 --PLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMATSWQVFDILNGKPYEPEFTSDDL 760 770 780 790 800 810 >>XP_011538132 (OMIM: 164012,615577) PREDICTED: nuclear (755 aa) initn: 385 init1: 178 opt: 396 Z-score: 315.5 bits: 67.8 E(85289): 7.8e-11 Smith-Waterman score: 399; 37.8% identity (63.4% similar) in 238 aa overlap (72-297:341-576) 50 60 70 80 90 pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKG-- :.::. ::::::: . .. ... .. XP_011 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 320 330 340 350 360 370 100 110 120 130 140 150 pF1KB6 DLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS ::. .:. :.:.::::::::::.: .. :: .: :: : : .:.. .::: . : : XP_011 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 380 390 400 410 420 430 160 170 180 190 200 210 pF1KB6 --VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNG . .: :: .: . ..:. ...: .::: ..:::. ::.:.: : .: XP_011 ELLRALLQS-GAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGG 440 450 460 470 480 220 230 240 250 260 270 pF1KB6 RTALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLT--WGRPS-TRIQQQLG-QL :::::::..... ::. :. : :.:: :. : .: .:. : :. ::. . : .. XP_011 RTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADI 490 500 510 520 530 540 280 290 300 310 pF1KB6 TLEN---LQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL :: : :: .: :..:: : XP_011 HAENEEPLCPLPSPPTSDS-DSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNT 550 560 570 580 590 600 >>XP_011538133 (OMIM: 164012,615577) PREDICTED: nuclear (755 aa) initn: 385 init1: 178 opt: 396 Z-score: 315.5 bits: 67.8 E(85289): 7.8e-11 Smith-Waterman score: 399; 37.8% identity (63.4% similar) in 238 aa overlap (72-297:341-576) 50 60 70 80 90 pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKG-- :.::. ::::::: . .. ... .. XP_011 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 320 330 340 350 360 370 100 110 120 130 140 150 pF1KB6 DLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS ::. .:. :.:.::::::::::.: .. :: .: :: : : .:.. .::: . : : XP_011 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 380 390 400 410 420 430 160 170 180 190 200 210 pF1KB6 --VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNG . .: :: .: . ..:. ...: .::: ..:::. ::.:.: : .: XP_011 ELLRALLQS-GAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGG 440 450 460 470 480 220 230 240 250 260 270 pF1KB6 RTALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLT--WGRPS-TRIQQQLG-QL :::::::..... ::. :. : :.:: :. : .: .:. : :. ::. . : .. XP_011 RTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADI 490 500 510 520 530 540 280 290 300 310 pF1KB6 TLEN---LQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL :: : :: .: :..:: : XP_011 HAENEEPLCPLPSPPTSDS-DSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNT 550 560 570 580 590 600 >>NP_001309864 (OMIM: 164012,615577) nuclear factor NF-k (858 aa) initn: 385 init1: 178 opt: 396 Z-score: 314.9 bits: 67.9 E(85289): 8.5e-11 Smith-Waterman score: 399; 37.8% identity (63.4% similar) in 238 aa overlap (72-297:444-679) 50 60 70 80 90 pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKG-- :.::. ::::::: . .. ... .. NP_001 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 420 430 440 450 460 470 100 110 120 130 140 150 pF1KB6 DLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS ::. .:. :.:.::::::::::.: .. :: .: :: : : .:.. .::: . : : NP_001 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 480 490 500 510 520 530 160 170 180 190 200 210 pF1KB6 --VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNG . .: :: .: . ..:. ...: .::: ..:::. ::.:.: : .: NP_001 ELLRALLQS-GAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGG 540 550 560 570 580 590 220 230 240 250 260 270 pF1KB6 RTALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLT--WGRPS-TRIQQQLG-QL :::::::..... ::. :. : :.:: :. : .: .:. : :. ::. . : .. NP_001 RTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADI 600 610 620 630 640 650 280 290 300 310 pF1KB6 TLEN---LQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL :: : :: .: :..:: : NP_001 HAENEEPLCPLPSPPTSDS-DSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNT 660 670 680 690 700 710 317 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:31:52 2016 done: Fri Nov 4 17:31:54 2016 Total Scan time: 7.040 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]